$115+ Cheap flights from Islip, NY (ISP) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — STL
Jun 3 — Jun 101
Round-trip
1 adult, Economy
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Find cheap flights from Islip to Missouri with Cheapflights
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Cheapest flights from Islip to MissouriExplore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
Explore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:28 pm
ISP
- STL
2 stops28h 02m
Multiple Airlines
Tue 9/14:10 pm
STL
- ISP
1 stop16h 53m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Multiple Airlines
Mon 6/85:27 pm
STL
- ISP
2 stops24h 11m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Thu 6/46:33 pm
STL
- ISP
2 stops38h 42m
Frontier
Deal found 5/1![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Thu 6/117:38 pm
STL
- ISP
2 stops24h 19m
Frontier
Deal found 4/29![Frontier logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:57 am
ISP
- STL
2 stops12h 52m
Multiple Airlines
Sun 6/214:17 pm
STL
- ISP
1 stop27h 40m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- STL
1 stop13h 57m
Frontier
Sun 6/74:19 pm
STL
- ISP
1 stop16h 46m
Frontier
Deal found 5/1![Frontier logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Mon 6/84:19 pm
STL
- ISP
1 stop22h 37m
Frontier
Deal found 4/29![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:12 am
ISP
- STL
1 stop14h 09m
Frontier
Thu 5/214:19 pm
STL
- ISP
1 stop16h 46m
Frontier
Deal found 5/2![Frontier logo]()
$337
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:00 pm
ISP
- STL
1 stop6h 25m
Southwest
Tue 9/11:40 pm
STL
- ISP
1 stop6h 25m
Southwest
Deal found 5/1![Southwest logo]()
$343
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:50 pm
ISP
- STL
1 stop6h 20m
Southwest
Thu 6/114:30 pm
STL
- ISP
1 stop6h 10m
Southwest
Deal found 4/29![Southwest logo]()
$344
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:55 pm
ISP
- MCI
1 stop4h 35m
Southwest
Sat 10/34:10 pm
MCI
- ISP
1 stop4h 40m
Southwest
Deal found 4/29![Southwest logo]()
$384
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am
ISP
- MCI
1 stop5h 00m
Southwest
Sun 10/189:55 am
MCI
- ISP
1 stop6h 15m
Southwest
Deal found 4/30![Southwest logo]()
$427
Best flights from Islip to MissouriDiscover carefully curated flight deals from Islip to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
Discover carefully curated flight deals from Islip to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:28 pm
ISP
- STL
2 stops28h 02m
Multiple Airlines
Tue 9/14:10 pm
STL
- ISP
1 stop16h 53m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Thu 6/46:33 pm
STL
- ISP
2 stops38h 42m
Frontier
Deal found 5/1![Frontier logo]()
$279
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:00 pm
ISP
- STL
1 stop6h 25m
Southwest
Tue 9/11:40 pm
STL
- ISP
1 stop6h 25m
Southwest
Deal found 5/1![Southwest logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Thu 6/117:38 pm
STL
- ISP
2 stops24h 19m
Frontier
Deal found 4/29![Frontier logo]()
$309
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:50 pm
ISP
- STL
1 stop6h 20m
Southwest
Thu 6/114:30 pm
STL
- ISP
1 stop6h 10m
Southwest
Deal found 4/29![Southwest logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Mon 6/84:19 pm
STL
- ISP
1 stop22h 37m
Frontier
Deal found 4/29![Frontier logo]()
$320
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:30 pm
ISP
- STL
2 stops7h 00m
Southwest
Sun 6/75:50 am
STL
- ISP
1 stop9h 50m
Southwest
Deal found 5/1![Southwest logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:12 am
ISP
- STL
1 stop14h 09m
Frontier
Thu 5/214:19 pm
STL
- ISP
1 stop16h 46m
Frontier
Deal found 5/2![Frontier logo]()
$337
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
ISP
- MCI
1 stop4h 45m
Southwest
Sun 7/263:00 pm
MCI
- ISP
1 stop8h 15m
Southwest
Deal found 5/2![Southwest logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:12 am
ISP
- STL
1 stop14h 09m
Frontier
Mon 5/189:18 pm
STL
- ISP
2 stops35h 47m
Frontier
Deal found 4/29![Frontier logo]()
$389
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:30 pm
ISP
- MCI
1 stop11h 10m
Southwest
Sat 5/305:25 pm
MCI
- ISP
1 stop4h 55m
Southwest
Deal found 5/3![Southwest logo]()
$431
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:50 pm
ISP
- MCI
2 stops7h 20m
Southwest
Wed 8/59:40 am
MCI
- ISP
2 stops6h 15m
Southwest
Deal found 5/2![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:45 pm
ISP
- MCI
2 stops9h 40m
Southwest
Mon 6/226:05 pm
MCI
- ISP
1 stop4h 30m
Southwest
Deal found 4/30![Southwest logo]()
$501
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:50 pm
ISP
- MCI
2 stops7h 40m
Southwest
Sun 6/216:00 am
MCI
- ISP
1 stop9h 40m
Southwest
Deal found 4/30![Southwest logo]()
$570
Last-minute flights from Islip to MissouriDiscover last-minute flight deals from Islip to Missouri. Data last updated May 4, 2026 and is based on user searches.
Discover last-minute flight deals from Islip to Missouri. Data last updated May 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:07 pm
ISP
- MCI
1 stop25h 59m
Multiple Airlines
Fri 5/810:35 am
MCI
- ISP
2 stops29h 54m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$699
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:07 pm
ISP
- MCI
1 stop18h 22m
Multiple Airlines
Sun 5/1010:35 am
MCI
- ISP
1 stop22h 30m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$668
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:12 am
ISP
- STL
1 stop14h 09m
Frontier
Mon 5/189:18 pm
STL
- ISP
2 stops35h 47m
Frontier
Deal found 4/29![Frontier logo]()
$389
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:10 pm
ISP
- STL
1 stop7h 30m
Southwest
Mon 5/185:00 am
STL
- ISP
1 stop5h 50m
Southwest
Deal found 4/29![Southwest logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:12 am
ISP
- STL
1 stop14h 09m
Frontier
Thu 5/214:19 pm
STL
- ISP
1 stop16h 46m
Frontier
Deal found 5/2![Frontier logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2211:00 am
ISP
- STL
1 stop13h 57m
Frontier
Tue 5/266:33 pm
STL
- ISP
2 stops38h 32m
Frontier
Deal found 4/29![Frontier logo]()
$350
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:30 pm
ISP
- MCI
1 stop11h 10m
Southwest
Sat 5/305:25 pm
MCI
- ISP
1 stop4h 55m
Southwest
Deal found 5/3![Southwest logo]()
$431
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Multiple Airlines
Mon 6/85:27 pm
STL
- ISP
2 stops24h 11m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Thu 6/46:33 pm
STL
- ISP
2 stops38h 42m
Frontier
Deal found 5/1![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Mon 6/84:19 pm
STL
- ISP
1 stop22h 37m
Frontier
Deal found 4/29![Frontier logo]()
$320
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
ISP
- STL
2 stops8h 15m
Southwest
Thu 6/44:35 pm
STL
- ISP
2 stops6h 00m
Southwest
Deal found 4/29![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:30 pm
ISP
- STL
2 stops7h 45m
Southwest
Mon 6/84:25 pm
STL
- ISP
2 stops6h 10m
Southwest
Deal found 4/29![Southwest logo]()
$417
One-way flights from Islip to MissouriSearch for one-way flight options from Islip to Missouri. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
Search for one-way flight options from Islip to Missouri. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
This Frontier deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:41 pm
ISP
- STL
1 stop8h 08m
Frontier
Deal found 5/2![Frontier logo]()
$115
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:00 am
ISP
- STL
1 stop13h 57m
Frontier
Deal found 4/29![Frontier logo]()
$134
This eDestinos deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:00 am
ISP
- STL
1 stop13h 57m
Frontier
Deal found 5/1![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:57 am
ISP
- STL
2 stops13h 24m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:57 am
ISP
- STL
2 stops37h 24m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:38 pm
ISP
- MCI
1 stop16h 51m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:00 am
ISP
- MCI
1 stop23h 29m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$186
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:05 pm
ISP
- STL
2 stops6h 45m
Southwest
Deal found 4/29![Southwest logo]()
$194
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/284:41 pm
ISP
- STL
1 stop8h 18m
Frontier
Deal found 4/30![Frontier logo]()
$200
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:15 pm
ISP
- STL
1 stop6h 20m
Southwest
Deal found 5/4![Southwest logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:38 pm
ISP
- MCI
2 stops24h 51m
Frontier
Deal found 4/29![Frontier logo]()
$226
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:10 pm
ISP
- MCI
1 stop6h 20m
Southwest
Deal found 4/29![Southwest logo]()
$234
Find flight deals from Islip to Missouri
Keep the following information in mind while searching for Islip to Missouri flight deals. Data was last updated May 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Kiwi.com) |
One-way from | $115 (Frontier) |
Popular in | November |
Cheapest in | August |
Average price | $358 |
Cheapflights Fare Finder
Customize your flight search to find flights from Islip to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Islip to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Mon 8/24
2:28 pm-5:30 pm
2 stops28h 02m
Lambert-St Louis
Tue 9/1
4:10 pm-10:03 am
1 stop16h 53m
$243
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Thu 5/28
11:00 am-11:57 pm
1 stop13h 57m
Lambert-St Louis
Thu 6/4
6:33 pm-10:15 am
2 stops38h 42m
$279
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Mon 6/8
11:00 am-11:57 pm
1 stop13h 57m
Lambert-St Louis
Thu 6/11
7:38 pm-8:57 pm
2 stops24h 19m
$309
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Thu 5/28
11:00 am-11:57 pm
1 stop13h 57m
Lambert-St Louis
Mon 6/8
4:19 pm-3:56 pm
1 stop22h 37m
$320
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Sun 5/17
11:12 am-12:21 am
1 stop14h 09m
Lambert-St Louis
Thu 5/21
4:19 pm-10:05 am
1 stop16h 46m
$337
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Mon 8/24
5:00 pm-10:25 pm
1 stop6h 25m
Lambert-St Louis
Tue 9/1
1:40 pm-9:05 pm
1 stop6h 25m
$343
Quickest round-trip
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Mon 6/8
5:50 pm-11:10 pm
1 stop6h 20m
Lambert-St Louis
Thu 6/11
4:30 pm-11:40 pm
1 stop6h 10m
$344
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Fri 6/5
12:30 pm-6:30 pm
2 stops7h 00m
Lambert-St Louis
Sun 6/7
5:50 am-4:40 pm
1 stop9h 50m
$356
IslipSt. Louis
ISP - STL
ISPSTL
Islip Long Island
Thu 5/14
11:12 am-12:21 am
1 stop14h 09m
Lambert-St Louis
Mon 5/18
9:18 pm-10:05 am
2 stops35h 47m
$389
IslipKansas City
ISP - MCI
ISPMCI
Islip Long Island
Wed 7/22
6:00 am-9:45 am
1 stop4h 45m
Kansas City
Sun 7/26
3:00 pm-12:15 am
1 stop8h 15m
$427
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Islip to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Islip with our price prediction graph.
ISP-STL
ISP-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Islip to Missouri
ISP-USMO
ISP-STL
ISP-MCI
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 4, 2026.
Peruse reviews from past customers who have flown with Southwest from Islip to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Islip to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Islip to Missouri
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Complete your trip
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Islip and Missouri flights
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Islip to Missouri flights
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Top airline flying from Islip to Missouri
Discover the top airline that operate flights from Islip to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$366 | FlexibilityNo cancel fee | On-time63% |