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Missouri

$78+ Cheap flights from Islip, NY (ISP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — STL
Sep 1 — Sep 81
Tue 9/1
Tue 9/8
1 adult, Economy
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Cheap flight deals from Islip to Missouri

Cheapest flights from Islip to Missouri
Explore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.

This Trip.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:57 am
ISP
-
STL
1 stop6h 14m
Frontier
Thu 9/106:39 pm
STL
-
ISP
1 stop21h 19m
Frontier
Deal found 7/31$225
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:05 pm
ISP
-
STL
1 stop6h 35m
Southwest
Wed 9/301:40 pm
STL
-
ISP
1 stop6h 30m
Southwest
Deal found 7/30$255
This Trip.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:43 pm
ISP
-
STL
1 stop23h 51m
Frontier
Sun 9/135:19 pm
STL
-
ISP
1 stop22h 39m
Frontier
Deal found 7/28$261
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:10 pm
ISP
-
STL
1 stop6h 20m
Southwest
Mon 10/126:45 am
STL
-
ISP
1 stop6h 45m
Southwest
Deal found 7/30$304
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:10 am
ISP
-
STL
1 stop6h 25m
Southwest
Thu 9/1011:40 am
STL
-
ISP
2 stops8h 55m
Southwest
Deal found 7/31$314
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:05 pm
ISP
-
STL
2 stops7h 05m
Southwest
Sun 9/137:20 am
STL
-
ISP
1 stop7h 35m
Southwest
Deal found 7/28$315
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:40 am
ISP
-
STL
1 stop7h 55m
Southwest
Wed 12/26:20 am
STL
-
ISP
2 stops8h 55m
Southwest
Deal found 8/2$336
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:35 am
ISP
-
MCI
1 stop5h 30m
Southwest
Thu 12/36:25 am
MCI
-
ISP
1 stop4h 20m
Southwest
Deal found 8/2$431
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 am
ISP
-
MCI
2 stops8h 55m
Southwest
Fri 8/212:00 pm
MCI
-
ISP
1 stop7h 05m
Southwest
Deal found 7/30$469
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:55 pm
ISP
-
MCI
1 stop4h 35m
Southwest
Thu 8/132:00 pm
MCI
-
ISP
1 stop7h 05m
Southwest
Deal found 7/29$742
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:55 pm
ISP
-
MCI
1 stop4h 35m
Southwest
Sun 8/161:30 pm
MCI
-
ISP
2 stops8h 05m
Southwest
Deal found 8/1$748
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:20 am
ISP
-
MCI
1 stop5h 00m
Southwest
Wed 8/1211:20 am
MCI
-
ISP
1 stop4h 35m
Southwest
Deal found 7/29$842

Find flight deals from Islip to Missouri

Keep the following information in mind while searching for Islip to Missouri flight deals. Data was last updated August 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$225
(Trip.com)

One-way from

$78
(Frontier)

Popular in

July

Cheapest in

January

Average price

$359
Provider with most accurate pricing for New York (NYC)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Lambert-St Louis flights.
Search Deals
From Islip Long Island to Missouri
Search Deals
One-way flight from Islip Long Island to Missouri
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from Islip to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 9/3

10:57 am-4:11 pm

1 stop6h 14m

Lambert-St Louis

Thu 9/10

6:39 pm-4:58 pm

1 stop21h 19m

$225

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 8/27

4:05 pm-10:05 pm

2 stops7h 00m

Lambert-St Louis

Wed 9/30

12:50 pm-9:10 pm

2 stops7h 20m

$265

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Wed 9/30

3:20 pm-9:45 pm

2 stops7h 25m

Lambert-St Louis

Wed 11/4

6:20 am-4:20 pm

2 stops9h 00m

$265

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Mon 10/5

7:10 pm-12:30 am

1 stop6h 20m

Lambert-St Louis

Mon 10/12

6:45 am-2:30 pm

1 stop6h 45m

$304

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 9/3

6:10 am-11:35 am

1 stop6h 25m

Lambert-St Louis

Thu 9/10

11:40 am-9:35 pm

2 stops8h 55m

$314

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 9/10

4:05 pm-10:10 pm

2 stops7h 05m

Lambert-St Louis

Sun 9/13

7:20 am-3:55 pm

1 stop7h 35m

$315

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Tue 11/24

5:40 am-12:35 pm

1 stop7h 55m

Lambert-St Louis

Wed 12/2

6:20 am-4:15 pm

2 stops8h 55m

$336
Quickest round-trip

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Fri 11/27

5:35 am-10:05 am

1 stop5h 30m

Kansas City

Thu 12/3

6:25 am-11:45 am

1 stop4h 20m

$431

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Sat 8/15

11:55 am-7:30 pm

1 stop8h 35m

Kansas City

Fri 8/21

2:00 pm-10:05 pm

1 stop7h 05m

$469

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Fri 11/27

7:30 am-7:55 pm

3 stops13h 25m

Kansas City

Thu 12/3

11:30 am-10:58 am

2 stops22h 28m

$1,064

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Islip to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Missouri

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 2, 2026.
Peruse reviews from past customers who have flown with Southwest from Islip to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,229 reviews

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,229 reviews
Southwest
8.0
Very good
4,229 reviews

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Islip to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Missouri?

    If you book a flight to Missouri from Islip, you will be flying from Long Island, which is the city’s only airport. Islip Long Island (ISP) is located 7.2 mi from the center of Islip.

  • How long is the flight from Islip, New York to Missouri?

    There are many flights that can get you from Islip, New York to Missouri in 6h 14m. Fly via Frontier or Southwest to get the fastest option. Airlines will cover a distance of 926 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Islip, New York to Missouri?

    While some choose either Islip Long Island - Kansas City or Islip Long Island - Columbia Regional, Islip Long Island - Lambert-St Louis is the most popular route from Islip, New York to Missouri.

  • Can I find deals for flights from Islip to Missouri that include hotel bookings?

    Yes. In addition to deals on Islip to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Missouri.

  • Can I find deals for business class flights from Islip to Missouri?

    Yes. Cheapflights offers flight deals from Islip to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Islip to Missouri

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Top airline flying from Islip to Missouri

Discover the top airline that operate flights from Islip to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$246Average$359FlexibilityNo cancel feeOn-time63%

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