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$103+ Cheap flights from Islip, NY (ISP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — STL
ago. 4 — ago. 111
lun. 8/4
lun. 8/11
1 adult, Economy
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Cheap flight deals from Islip to Missouri

Keep the following information in mind while searching for Islip to Missouri flight deals. Data was last updated julio 30, 2025.

Round-trip from

$222
(Southwest)

One-way from

$103
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$398
From Islip Long Island to Missouri
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One-way flight from Islip Long Island to Missouri
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Highest demand for flights based on searches. 14% potential increase in price ($63 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Islip to Missouri

Cheapest flights from Islip to Missouri
Explore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/166:05 amISP - STL
1 stop4h 30mSouthwest
sáb. 9/2012:30 pmSTL - ISP
1 stop8h 10mSouthwest
Deal found 7/29$222
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/58:00 amISP - STL
1 stop16h 47mFrontier
mar. 8/125:40 pmSTL - ISP
1 stop25h 12mFrontier
Deal found 7/28$265

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
Use the filters below to find and compare flights from Islip to Missouri that are best for you.

Fly from

Islip

Fly to

Missouri

Route

Depart

Return

Price

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

mar. 9/16

6:05 am-9:35 am

1 stop4h 30m

Lambert-St Louis

sáb. 9/20

12:30 pm-9:40 pm

1 stop8h 10m

$222

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

jue. 8/14

6:00 am-11:47 pm

1 stop18h 47m

Lambert-St Louis

dom. 8/17

5:40 pm-7:52 pm

1 stop25h 12m

$275

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

sáb. 10/25

11:40 am-4:53 pm

1 stop6h 13m

$103

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

jue. 10/2

5:35 pm-11:00 pm

1 stop6h 25m

$164

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

jue. 10/2

11:40 am-10:18 am

3 stops23h 38m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Islip to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Missouri

What is the cheapest month to book a flight from Islip, New York to Missouri?

Currently, August is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $311). Flying from Islip, New York to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to MO?

Find hourly flight availability from Islip to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Islip, New York to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated julio 30, 2025.
Peruse reviews from past customers who have flown with Southwest and Frontier from Islip to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,237 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Islip to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Missouri?

    If you book a flight to Missouri from Islip, you will be flying from Long Island, which is the city’s only airport. Islip Long Island (ISP) is located 7.2 mi from the center of Islip.

  • What are the most popular routes from Islip, New York to Missouri?

    While some choose either Islip Long Island - Kansas City or Islip Long Island - Columbia Regional, Islip Long Island - Lambert-St Louis is the most popular route from Islip, New York to Missouri.

  • Can I find deals for flights from Islip to Missouri that include hotel bookings?

    Yes. In addition to deals on Islip to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Missouri.

  • Can I find deals for business class flights from Islip to Missouri?

    Yes. Cheapflights offers flight deals from Islip to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $311). Flying from Islip, New York to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Islip to Missouri

Discover the top airline that operate flights from Islip to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$304Average$386FlexibilityNo cancel feeOn-time63%

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