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$159+ Cheap flights from Islip, NY (ISP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — STL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Islip to Missouri

Keep the following information in mind while searching for Islip to Missouri flight deals. Data was last updated June 12, 2025.

Round-trip from

$289
(Southwest)

One-way from

$159
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$385
From Islip Long Island to Missouri
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One-way flight from Islip Long Island to Missouri
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Highest demand for flights based on searches. 16% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Islip to Missouri

Cheapest flights from Islip to Missouri
Explore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:00 amISP - STL
1 stop6h 30mSouthwest
Mon 8/255:30 amSTL - ISP
1 stop5h 30mSouthwest
Deal found 6/12$289
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/95:40 amISP - MCI
1 stop6h 25mSouthwest
Mon 8/114:35 pmMCI - ISP
1 stop5h 10mSouthwest
Deal found 6/11$353
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/258:21 pmISP - STL
1 stop28h 32mFrontier
Sun 6/292:36 pmSTL - ISP
2 stops52h 00mFrontier
Deal found 6/10$518
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1110:44 amISP - STL
3 stops28h 55mMultiple Airlines
Sun 7/1310:47 amSTL - ISP
3 stops22h 17mMultiple Airlines
Deal found 6/10$627
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/247:39 pmISP - MCI
3 stops22h 59mMultiple Airlines
Thu 8/287:39 pmMCI - ISP
2 stops18h 40mMultiple Airlines
Deal found 6/10$665

Cheapflights Fare Finder

Customize your flight search to find flights from Islip to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Islip to Missouri that are best for you.

Fly from

Islip

Fly to

Missouri

Route

Depart

Return

Price

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Fri 8/22

6:00 am-11:30 am

1 stop6h 30m

Lambert-St Louis

Mon 8/25

5:30 am-12:00 pm

1 stop5h 30m

$289

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Sat 8/9

5:40 am-11:05 am

1 stop6h 25m

Kansas City

Mon 8/11

4:35 pm-10:45 pm

1 stop5h 10m

$353

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Wed 6/25

8:21 pm-11:53 pm

1 stop28h 32m

Lambert-St Louis

Sun 6/29

2:36 pm-7:36 pm

2 stops52h 00m

$518

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Fri 7/11

10:44 am-2:39 pm

3 stops28h 55m

Lambert-St Louis

Sun 7/13

10:47 am-10:04 am

3 stops22h 17m

$627

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Sun 8/24

7:39 pm-5:38 pm

3 stops22h 59m

Kansas City

Thu 8/28

7:39 pm-3:19 pm

2 stops18h 40m

$665

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Mon 8/25

8:59 am-2:21 pm

1 stop6h 22m

$159

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Sun 8/3

6:00 am-12:00 pm

1 stop7h 00m

$189

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Sun 8/3

2:19 pm-2:37 pm

3 stops25h 18m

$1,024

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Islip to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Missouri

What is the cheapest month to book a flight from Islip, New York to Missouri?

Currently, August is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $311). Flying from Islip, New York to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to MO?

Find hourly flight availability from Islip to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Islip, New York to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 12, 2025.
To help decide which airline to fly from Islip to Missouri, see what other customers have to say about Southwest and Frontier. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Frontier
5.9
Fair
3,295 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Crew

8.6

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Islip to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Missouri?

    If you book a flight to Missouri from Islip, you will be flying from Long Island, which is the city’s only airport. Islip Long Island (ISP) is located 7.2 mi from the center of Islip.

  • What are the most popular routes from Islip, New York to Missouri?

    While some choose either Islip Long Island - Joplin or Islip Long Island - Lambert-St Louis, Islip Long Island - Kansas City is the most popular route from Islip, New York to Missouri.

  • Can I find deals for flights from Islip to Missouri that include hotel bookings?

    Yes. In addition to deals on Islip to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Missouri.

  • Can I find deals for business class flights from Islip to Missouri?

    Yes. Cheapflights offers flight deals from Islip to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $311). Flying from Islip, New York to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Islip to Missouri

Discover the top airline that operate flights from Islip to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$348Average$391FlexibilityNo cancel feeOn-time63%

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