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$151+ Cheap flights from Islip, NY (ISP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — STL
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Islip to Missouri

Cheapest flights from Islip to Missouri
Explore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:10 am
ISP
-
STL
1 stop6h 25m
Southwest
Sun 8/96:00 am
STL
-
ISP
1 stop8h 55m
Southwest
Deal found 3/12$402
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:15 pm
ISP
-
STL
1 stop8h 25m
Southwest
Fri 4/34:45 pm
STL
-
ISP
1 stop6h 10m
Southwest
Deal found 3/15$411
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:40 pm
ISP
-
STL
1 stop7h 35m
Southwest
Thu 4/27:15 am
STL
-
ISP
1 stop8h 15m
Southwest
Deal found 3/14$434
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:10 pm
ISP
-
MCI
1 stop6h 50m
Southwest
Mon 5/255:35 pm
MCI
-
ISP
1 stop4h 55m
Southwest
Deal found 3/15$476
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:55 pm
ISP
-
STL
1 stop6h 10m
Southwest
Sun 4/55:50 am
STL
-
ISP
1 stop4h 55m
Southwest
Deal found 3/15$481
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:10 am
ISP
-
STL
1 stop8h 45m
Southwest
Sun 4/53:50 pm
STL
-
ISP
1 stop6h 05m
Southwest
Deal found 3/15$495
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:55 pm
ISP
-
MCI
1 stop8h 58m
Multiple Airlines
Sun 4/125:45 am
MCI
-
ISP
2 stops37h 20m
Multiple Airlines
Deal found 3/16$582
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:01 pm
ISP
-
MCI
1 stop8h 52m
Multiple Airlines
Sun 4/1212:24 pm
MCI
-
ISP
2 stops32h 14m
Multiple Airlines
Deal found 3/16$632
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:30 pm
ISP
-
MCI
1 stop7h 10m
Southwest
Sun 4/126:15 am
MCI
-
ISP
1 stop4h 35m
Southwest
Deal found 3/16$768

Find flight deals from Islip to Missouri

Keep the following information in mind while searching for Islip to Missouri flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$402
(Southwest)

One-way from

$151
(Southwest)

Popular in

November

Cheapest in

August

Average price

$361
Provider with most accurate pricing for New York (NYC)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Lambert-St Louis flights.
Search Deals
From Islip Long Island to Missouri
Search Deals
One-way flight from Islip Long Island to Missouri
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Islip to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Mon 3/30

5:15 pm-12:40 am

1 stop8h 25m

Lambert-St Louis

Fri 4/3

4:45 pm-11:55 pm

1 stop6h 10m

$411

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Fri 8/7

4:05 pm-11:05 pm

2 stops8h 00m

Lambert-St Louis

Sun 8/9

6:00 am-3:55 pm

1 stop8h 55m

$415

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Sun 3/29

5:40 pm-12:15 am

1 stop7h 35m

Lambert-St Louis

Thu 4/2

7:15 am-4:30 pm

1 stop8h 15m

$434

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Fri 5/22

5:10 pm-11:00 pm

1 stop6h 50m

Kansas City

Mon 5/25

5:35 pm-11:30 pm

1 stop4h 55m

$476
Quickest round-trip

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 4/2

5:55 pm-11:05 pm

1 stop6h 10m

Lambert-St Louis

Sun 4/5

5:50 am-11:45 am

1 stop4h 55m

$481

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Wed 4/1

6:10 am-1:55 pm

1 stop8h 45m

Lambert-St Louis

Sun 4/5

3:50 pm-10:55 pm

1 stop6h 05m

$495

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Fri 4/10

4:01 pm-11:53 pm

1 stop8h 52m

Kansas City

Sun 4/12

12:24 pm-9:38 pm

2 stops32h 14m

$632

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Fri 4/10

4:30 pm-10:40 pm

1 stop7h 10m

Kansas City

Sun 4/12

6:15 am-11:50 am

1 stop4h 35m

$768
Cheapest one-way
Quickest one-way

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 4/30

4:30 pm-11:25 pm

1 stop7h 55m

$151

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Mon 4/20

4:07 pm-11:19 pm

1 stop8h 12m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Islip to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Missouri

What is the cheapest month to book a flight from Islip, New York to Missouri?

Currently, March is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $109). Flying from Islip, New York to Missouri in February is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 17, 2026.
Peruse reviews from past customers who have flown with Southwest from Islip to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,320 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..
Southwest
8.0
Very good
4,320 reviews
Southwest
8.0
Very good
4,320 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Islip to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Missouri?

    If you book a flight to Missouri from Islip, you will be flying from Long Island, which is the city’s only airport. Islip Long Island (ISP) is located 7.2 mi from the center of Islip.

  • How long is the flight from Islip, New York to Missouri?

    There are many flights that can get you from Islip, New York to Missouri in 8h 25m. Fly via Southwest to get the fastest option. Airlines will cover a distance of 926 mi.

  • What are the most popular routes from Islip, New York to Missouri?

    While some choose either Islip Long Island - Kansas City or Islip Long Island - Columbia Regional, Islip Long Island - Lambert-St Louis is the most popular route from Islip, New York to Missouri.

  • Can I find deals for flights from Islip to Missouri that include hotel bookings?

    Yes. In addition to deals on Islip to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Missouri.

  • Can I find deals for business class flights from Islip to Missouri?

    Yes. Cheapflights offers flight deals from Islip to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Missouri?

    Currently, March is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $109). Flying from Islip, New York to Missouri in February is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Islip to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Islip to Missouri

Discover the top airline that operate flights from Islip to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$317Average$482FlexibilityNo cancel feeOn-time63%

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