HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$65+ Cheap flights from Islip, NY (ISP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — STL
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Islip to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Islip to Missouri

Cheapest flights from Islip to Missouri
Explore the most affordable flight options available from Islip to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:58 pmISP - STL
1 stop21h 19mFrontier
Sun 11/162:12 pmSTL - ISP
1 stop19h 25mFrontier
Deal found 10/28$198
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:37 pmISP - STL
1 stop16h 43mFrontier
Sun 11/162:12 pmSTL - ISP
1 stop19h 25mFrontier
Deal found 10/30$236
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:58 pmISP - MCI
1 stop20h 30mMultiple Airlines
Wed 11/126:00 amMCI - ISP
2 stops35h 56mMultiple Airlines
Deal found 10/29$439
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:40 pmISP - MCI
1 stop5h 10mSouthwest
Wed 11/122:40 pmMCI - ISP
1 stop6h 25mSouthwest
Deal found 10/29$682
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:20 pmISP - STL
1 stop11h 13mFrontier
Fri 1/210:40 amSTL - ISP
1 stop8h 00mFrontier
Deal found 10/29$1,080
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:04 pmISP - STL
1 stop9h 29mFrontier
Fri 1/210:40 amSTL - ISP
1 stop8h 00mFrontier
Deal found 10/29$1,140
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/282:04 pmISP - STL
1 stop9h 29mFrontier
Fri 1/210:40 amSTL - ISP
1 stop8h 00mFrontier
Deal found 10/29$1,300

Cheap flight deals from Islip to Missouri

Keep the following information in mind while searching for Islip to Missouri flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$198
(Mytrip)

One-way from

$65
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$397
Provider with most accurate pricing for New York (NYC)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Lambert-St Louis flights.
Search Deals
From Islip Long Island to Missouri
Search Deals
One-way flight from Islip Long Island to Missouri
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Islip to Missouri that are best for you.

Fly from

Islip

Fly to

Missouri

Route

Depart

Return

Price

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Wed 11/12

4:58 pm-1:17 pm

1 stop21h 19m

Lambert-St Louis

Sun 11/16

2:12 pm-10:37 am

1 stop19h 25m

$198

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 11/13

6:37 pm-10:20 am

1 stop16h 43m

Lambert-St Louis

Sun 11/16

2:12 pm-10:37 am

1 stop19h 25m

$236

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Fri 2/27

1:10 pm-7:11 pm

1 stop7h 01m

Lambert-St Louis

Sun 3/1

8:45 am-4:06 pm

1 stop6h 21m

$430

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Tue 12/30

12:20 pm-10:33 pm

1 stop11h 13m

Lambert-St Louis

Fri 1/2

10:40 am-7:40 pm

1 stop8h 00m

$1,080

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Mon 12/29

2:04 pm-10:33 pm

1 stop9h 29m

Lambert-St Louis

Fri 1/2

10:40 am-7:40 pm

1 stop8h 00m

$1,140

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Sun 12/28

2:04 pm-10:33 pm

1 stop9h 29m

Lambert-St Louis

Fri 1/2

10:40 am-7:40 pm

1 stop8h 00m

$1,300

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 11/13

6:37 pm-4:20 pm

1 stop22h 43m

$65

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Sat 1/10

3:34 pm-12:39 pm

1 stop22h 05m

$91

IslipSt. Louis

ISP - STL

ISPSTL

Islip Long Island

Thu 11/13

11:40 am-10:20 am

2 stops23h 40m

$132

IslipKansas City

ISP - MCI

ISPMCI

Islip Long Island

Sat 11/22

6:00 am-4:52 pm

1 stop11h 52m

$141

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 14 results
1
2

Best time to book a flight from Islip to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Missouri

What is the cheapest month to book a flight from Islip, New York to Missouri?

Currently, March is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $61). Flying from Islip, New York to Missouri in July is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to MO?

Find hourly flight availability from Islip to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from Islip, New York to Missouri at noon. Doing so could potentially save you 35% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Southwest from Islip to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Islip to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Missouri?

    If you book a flight to Missouri from Islip, you will be flying from Long Island, which is the city’s only airport. Islip Long Island (ISP) is located 7.2 mi from the center of Islip.

  • How long is the flight from Islip, New York to Missouri?

    There are many flights that can get you from Islip, New York to Missouri in 21h 19m. Fly via Frontier to get the fastest option. Airlines will cover a distance of 926 mi.

  • What are the most popular routes from Islip, New York to Missouri?

    While some choose either Islip Long Island - Kansas City or Islip Long Island - Columbia Regional, Islip Long Island - Lambert-St Louis is the most popular route from Islip, New York to Missouri.

  • Can I find deals for flights from Islip to Missouri that include hotel bookings?

    Yes. In addition to deals on Islip to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Missouri.

  • Can I find deals for business class flights from Islip to Missouri?

    Yes. Cheapflights offers flight deals from Islip to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Missouri?

    Currently, March is the cheapest month in which you can book a flight from Islip, New York to Missouri (average of $61). Flying from Islip, New York to Missouri in July is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Islip to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
Newark to Miami flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Los Angeles flights
Newark to Fort Lauderdale flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
John F Kennedy Intl to Dallas/Fort Worth flights
LaGuardia to Dallas/Fort Worth flights
Newark to Dallas/Fort Worth flights
John F Kennedy Intl to Las Vegas flights
Newark to Los Angeles flights
John F Kennedy Intl to O'Hare Intl flights
John F Kennedy Intl to San Francisco flights
John F Kennedy Intl to West Palm Beach flights
Newark to Orlando flights
Newark to Las Vegas flights
John F Kennedy Intl to Tampa flights
LaGuardia to Hobby flights
John F Kennedy Intl to Atlanta flights
Newark to San Francisco flights
LaGuardia to Orlando flights
LaGuardia to Tampa flights
Newark to West Palm Beach flights
Newark to Tampa flights
John F Kennedy Intl to Hobby flights
Newark to Hobby flights
LaGuardia to Los Angeles flights
John F Kennedy Intl to Denver flights
John F Kennedy Intl to Sky Harbor Intl flights
Newark to New Orleans flights
Newark to Sky Harbor Intl flights
John F Kennedy Intl to New Orleans flights
LaGuardia to O'Hare Intl flights
John F Kennedy Intl to Seattle flights
Newark to O'Hare Intl flights
LaGuardia to West Palm Beach flights
Newark to Atlanta flights
LaGuardia to New Orleans flights
John F Kennedy Intl to Austin flights
John F Kennedy Intl to Nashville flights
LaGuardia to Las Vegas flights
LaGuardia to Atlanta flights
Newark to George Bush Intcntl flights
John F Kennedy Intl to George Bush Intcntl flights
Newark to Denver flights
LaGuardia to San Francisco flights
John F Kennedy Intl to San Diego flights
LaGuardia to George Bush Intcntl flights

Top airline flying from Islip to Missouri

Discover the top airline that operate flights from Islip to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$304Average$394FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.