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Missoula

$291+ Cheap flights from South Carolina to Missoula (MSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MSO
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from South Carolina to Missoula

Keep the following information in mind while searching for South Carolina to Missoula flight deals. Data was last updated September 15, 2025.

Round-trip from

$303
(United Airlines)

One-way from

$291
(American Airlines)
From South Carolina to Missoula Johnson-Bell Field
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One-way flight from South Carolina to Missoula Johnson-Bell Field
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Find flight deals from South Carolina to Missoula

Cheapest flights from South Carolina to Missoula
Explore the most affordable flight options available from South Carolina to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:27 pmCLT - MSO
1 stop6h 58mUnited Airlines
Tue 10/212:33 pmMSO - CLT
1 stop6h 41mUnited Airlines
Deal found 9/14$303
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:15 amGSP - MSO
1 stop7h 45mAmerican Airlines
Sat 10/41:51 pmMSO - GSP
1 stop6h 39mAmerican Airlines
Deal found 9/15$339
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/214:20 pmCLT - MSO
2 stops21h 58mAlaska Airlines
Fri 10/246:40 pmMSO - CLT
2 stops15h 37mAlaska Airlines
Deal found 9/15$389
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:30 pmGSP - MSO
1 stop6h 52mUnited Airlines
Sat 9/276:25 amMSO - GSP
1 stop6h 43mUnited Airlines
Deal found 9/15$419
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:32 pmCAE - MSO
2 stops8h 45mDelta
Tue 11/48:00 amMSO - CAE
2 stops11h 20mDelta
Deal found 9/15$424
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/214:27 pmCLT - MSO
1 stop6h 58mUnited Airlines
Fri 10/245:25 pmMSO - CLT
2 stops15h 09mUnited Airlines
Deal found 9/15$458
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:20 amCAE - MSO
2 stops13h 27mUnited Airlines
Sat 11/16:20 amMSO - CAE
2 stops13h 10mUnited Airlines
Deal found 9/14$479
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:30 amCLT - MSO
1 stop9h 30mAmerican Airlines
Fri 10/312:50 pmMSO - CLT
1 stop7h 14mAmerican Airlines
Deal found 9/14$481
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:20 pmCLT - MSO
2 stops8h 58mDelta
Fri 10/35:45 amMSO - CLT
1 stop8h 35mDelta
Deal found 9/14$486
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:29 amCLT - MSO
1 stop6h 58mUnited Airlines
Tue 10/76:25 amMSO - CLT
1 stop14h 49mUnited Airlines
Deal found 9/15$488
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2910:34 amCAE - MSO
2 stops13h 13mUnited Airlines
Tue 11/42:35 pmMSO - CAE
3 stops21h 12mUnited Airlines
Deal found 9/15$570
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:20 amCAE - MSO
2 stops13h 27mUnited Airlines
Sun 11/25:20 amMSO - CAE
2 stops25h 39mUnited Airlines
Deal found 9/14$639

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from South Carolina to Missoula that are best for you.

Fly from

South Carolina

Fly to

Missoula

Route

Depart

Return

Price

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Tue 10/14

4:27 pm-9:25 pm

1 stop6h 58m

Missoula Johnson-Bell Field

Tue 10/21

2:33 pm-11:14 pm

1 stop6h 41m

$303

GreenvilleMissoula

GSP - MSO

GSPMSO

Greenville

Tue 9/30

7:15 am-1:00 pm

1 stop7h 45m

Missoula Johnson-Bell Field

Sat 10/4

1:51 pm-10:30 pm

1 stop6h 39m

$339

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Tue 10/21

4:20 pm-12:18 pm

2 stops21h 58m

Missoula Johnson-Bell Field

Fri 10/24

6:40 pm-12:17 pm

2 stops15h 37m

$389

ColumbiaMissoula

CAE - MSO

CAEMSO

Columbia Metropolitan

Wed 10/29

5:40 am-12:27 pm

2 stops8h 47m

Missoula Johnson-Bell Field

Tue 11/4

8:00 am-9:20 pm

2 stops11h 20m

$424

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Tue 3/3

4:00 pm-9:30 pm

1 stop7h 30m

Missoula Johnson-Bell Field

Wed 3/4

6:15 am-11:25 pm

2 stops15h 10m

$442

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Tue 10/21

4:27 pm-9:25 pm

1 stop6h 58m

Missoula Johnson-Bell Field

Fri 10/24

2:33 pm-3:13 pm

1 stop22h 40m

$462

ColumbiaMissoula

CAE - MSO

CAEMSO

Columbia Metropolitan

Tue 10/28

10:20 am-9:47 pm

2 stops13h 27m

Missoula Johnson-Bell Field

Sat 11/1

6:20 am-9:30 pm

2 stops13h 10m

$479

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Mon 9/29

5:30 am-1:00 pm

1 stop9h 30m

Missoula Johnson-Bell Field

Fri 10/3

12:50 pm-10:04 pm

1 stop7h 14m

$481

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Mon 9/29

5:20 pm-12:18 am

2 stops8h 58m

Missoula Johnson-Bell Field

Fri 10/3

5:45 am-4:20 pm

1 stop8h 35m

$486

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Fri 10/3

11:27 am-9:25 pm

2 stops11h 58m

Missoula Johnson-Bell Field

Tue 10/7

5:10 pm-3:13 pm

1 stop20h 03m

$493

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 27 results
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Best time to book a flight from South Carolina to Missoula

Have a flexible travel schedule? Discover the best time to fly to Missoula from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missoula

What is the cheapest month to book a flight from South Carolina to Missoula?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Missoula (average of $365). Flying from South Carolina to Missoula in March is currently the most expensive (average of $505). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MSO?

Find hourly flight availability from South Carolina to Missoula. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from South Carolina to Missoula, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Missoula from South Carolina?

    For a flight from South Carolina to Missoula, you will be flying into Johnson-Bell Field. Missoula Johnson-Bell Field (MSO) is just 5.5 mi from the center of the city.

  • How long is the flight from South Carolina to Missoula?

    United Airlines, American Airlines, and Alaska Airlines can get you from South Carolina to Missoula in just under 6h 58m. Your travel time can differ by up to 15h. There are 1887 mi between South Carolina and Missoula. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Missoula one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $291. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from South Carolina to Missoula for a low price.

  • What are the most popular routes from South Carolina to Missoula?

    When deciding which route to take from South Carolina to Missoula consider Charlotte Douglas - Missoula Johnson-Bell Field, Charleston - Missoula Johnson-Bell Field or Columbia Metropolitan - Missoula Johnson-Bell Field as they are the most popular.

  • Can I find deals for flights from South Carolina to Missoula that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missoula flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missoula?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missoula.

  • Can I find deals for business class flights from South Carolina to Missoula?

    Yes. Cheapflights offers flight deals from South Carolina to Missoula by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Missoula?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Missoula (average of $365). Flying from South Carolina to Missoula in March is currently the most expensive (average of $505). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Missoula

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Top 2 airlines flying from South Carolina to Missoula

Discover the top 2 airlines that operate flights from South Carolina to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$288Average$561FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$568FlexibilityNo cancel feeOn-time71%

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