Missoula

$241+ Cheap flights from South Carolina to Missoula (MSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MSO
Jan 22 — Jan 291
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Cheap flight deals from South Carolina to Missoula

Cheapest flights from South Carolina to Missoula
Explore the most affordable flight options available from South Carolina to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:40 amCHS - MSO
2 stops12h 01mUnited Airlines
Sun 1/46:00 amMSO - CHS
1 stop7h 09mUnited Airlines
Deal found 12/21$818
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:40 amCHS - MSO
2 stops12h 01mUnited Airlines
Fri 1/26:00 amMSO - CHS
1 stop7h 09mUnited Airlines
Deal found 12/21$855
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:56 pmCHS - MSO
2 stops9h 37mDelta
Sun 1/46:15 pmMSO - CHS
2 stops13h 04mDelta
Deal found 12/21$859
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:20 amCLT - MSO
2 stops17h 21mUnited Airlines
Mon 1/56:00 amMSO - CLT
2 stops13h 59mUnited Airlines
Deal found 12/21$967
This Mytrip deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:00 amCLT - MSO
3 stops32h 30mMultiple Airlines
Mon 1/54:20 pmMSO - CLT
3 stops29h 09mMultiple Airlines
Deal found 12/21$1,012
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:56 pmCHS - MSO
2 stops9h 37mDelta
Sat 1/38:10 amMSO - CHS
2 stops10h 41mDelta
Deal found 12/21$1,049
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amCHS - MSO
1 stop8h 48mAmerican Airlines
Fri 1/21:18 pmMSO - CHS
1 stop8h 39mAmerican Airlines
Deal found 12/21$1,061
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:26 pmCLT - MSO
1 stop8h 07mDelta
Mon 1/55:00 amMSO - CLT
1 stop9h 00mDelta
Deal found 12/22$1,061
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:05 amCHS - MSO
2 stops9h 31mUnited Airlines
Sun 1/46:00 amMSO - CHS
1 stop7h 09mUnited Airlines
Deal found 12/21$1,078
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:50 pmCHS - MSO
1 stop8h 50mDelta
Sat 1/38:10 amMSO - CHS
2 stops10h 41mDelta
Deal found 12/21$1,113
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:05 amCHS - MSO
2 stops9h 31mUnited Airlines
Fri 1/26:00 amMSO - CHS
1 stop7h 09mUnited Airlines
Deal found 12/21$1,115

Find flight deals from South Carolina to Missoula

Keep the following information in mind while searching for South Carolina to Missoula flight deals. Data was last updated December 23, 2025.

Round-trip from

$309
(American Airlines)

One-way from

$241
(Delta)
From South Carolina to Missoula Johnson-Bell Field
One-way flight from South Carolina to Missoula Johnson-Bell Field

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from South Carolina to Missoula that are best for you.

Fly from

South Carolina

Fly to

Missoula

Route

Depart

Return

Price

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Wed 3/4

4:25 pm-9:57 pm

1 stop7h 32m

Missoula Johnson-Bell Field

Mon 3/9

2:35 pm-10:38 pm

1 stop6h 03m

$309

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Sun 1/18

7:50 am-12:50 pm

1 stop7h 00m

Missoula Johnson-Bell Field

Sun 1/25

1:21 pm-10:54 pm

1 stop7h 33m

$309

GreenvilleMissoula

GSP - MSO

GSPMSO

Greenville

Thu 2/5

10:32 am-8:45 pm

2 stops12h 13m

Missoula Johnson-Bell Field

Sun 2/8

1:21 pm-11:59 pm

1 stop8h 38m

$314

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Wed 3/4

9:59 am-8:01 pm

2 stops12h 02m

Missoula Johnson-Bell Field

Mon 3/9

6:04 pm-8:40 am

2 stops12h 36m

$319

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Thu 1/8

5:10 pm-12:29 am

1 stop9h 19m

Missoula Johnson-Bell Field

Mon 1/12

5:00 am-4:00 pm

1 stop9h 00m

$334

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Wed 1/21

7:22 pm-12:23 pm

1 stop19h 01m

Missoula Johnson-Bell Field

Wed 1/28

4:20 pm-6:22 pm

1 stop24h 02m

$336

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Wed 1/21

10:15 am-9:51 pm

2 stops13h 36m

Missoula Johnson-Bell Field

Wed 1/28

6:00 am-3:05 pm

1 stop7h 05m

$342

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Wed 1/21

11:28 am-8:14 pm

2 stops10h 46m

Missoula Johnson-Bell Field

Wed 1/28

7:55 am-9:06 pm

2 stops11h 11m

$347

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Fri 5/29

5:25 pm-12:24 am

1 stop8h 59m

Missoula Johnson-Bell Field

Fri 6/5

8:00 am-6:58 pm

1 stop8h 58m

$364

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Wed 6/3

4:55 pm-12:24 am

2 stops9h 29m

Missoula Johnson-Bell Field

Wed 6/10

6:10 pm-8:47 am

2 stops12h 37m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 25 results
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Best time to book a flight from South Carolina to Missoula

Have a flexible travel schedule? Discover the best time to fly to Missoula from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missoula

What is the cheapest month to book a flight from South Carolina to Missoula?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Missoula (average of $288). Flying from South Carolina to Missoula in December is currently the most expensive (average of $898). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MSO?

Find hourly flight availability from South Carolina to Missoula. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

One of the essential ways to save on airfare from South Carolina to Missoula is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 47% on airfare.

What is the cheapest day to fly from South Carolina to Missoula?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Missoula. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Missoula flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Missoula from South Carolina?

    For a flight from South Carolina to Missoula, you will be flying into Johnson-Bell Field. Missoula Johnson-Bell Field (MSO) is just 5.5 mi from the center of the city.

  • How long is the flight from South Carolina to Missoula?

    United Airlines, American Airlines, and Delta can get you from South Carolina to Missoula in just under 7h. Your travel time can differ by up to 5h 02m. There are 1887 mi between South Carolina and Missoula. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Missoula?

  • Can I find deals for flights from South Carolina to Missoula that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missoula flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missoula?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missoula.

  • Can I find deals for business class flights from South Carolina to Missoula?

    Yes. Cheapflights offers flight deals from South Carolina to Missoula by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Missoula?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Missoula (average of $288). Flying from South Carolina to Missoula in December is currently the most expensive (average of $898). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Missoula

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Missoula

Discover the top 2 airlines that operate flights from South Carolina to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$543FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$382Average$573FlexibilityNo cancel feeOn-time69%

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