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Missoula

$165+ Cheap flights from South Carolina to Missoula (MSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MSO
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Cheap flight deals from South Carolina to Missoula

Cheapest flights from South Carolina to Missoula
Explore the most affordable flight options available from South Carolina to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:46 am
GSP
-
MSO
1 stop6h 48m
United Airlines
Tue 9/112:40 pm
MSO
-
GSP
1 stop6h 31m
United Airlines
Deal found 2/17$309
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:18 pm
CLT
-
MSO
1 stop8h 19m
Delta
Mon 5/255:15 am
MSO
-
CLT
1 stop9h 13m
Delta
Deal found 2/15$309
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
CLT
-
MSO
2 stops10h 40m
Delta
Fri 6/53:30 pm
MSO
-
CLT
1 stop6h 25m
Delta
Deal found 2/17$314
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:55 pm
CLT
-
MSO
2 stops9h 29m
Delta
Wed 7/156:10 pm
MSO
-
CLT
2 stops12h 37m
Delta
Deal found 2/16$319
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:06 am
CLT
-
MSO
1 stop7h 32m
American Airlines
Mon 5/41:08 pm
MSO
-
CLT
1 stop8h 43m
American Airlines
Deal found 2/17$320
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:22 pm
CLT
-
MSO
1 stop7h 04m
United Airlines
Sat 8/1512:40 pm
MSO
-
CLT
1 stop6h 43m
United Airlines
Deal found 2/15$327
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
CLT
-
MSO
2 stops10h 40m
Delta
Sun 5/175:15 am
MSO
-
CLT
1 stop9h 13m
Delta
Deal found 2/16$329
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/134:00 pm
CHS
-
MSO
1 stop7h 57m
United Airlines
Tue 3/176:15 am
MSO
-
CHS
2 stops13h 01m
United Airlines
Deal found 2/16$334
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:15 am
CLT
-
MSO
2 stops11h 51m
United Airlines
Tue 5/56:15 am
MSO
-
CLT
2 stops13h 24m
United Airlines
Deal found 2/14$337
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:06 am
CLT
-
MSO
1 stop7h 32m
American Airlines
Sun 5/31:08 pm
MSO
-
CLT
1 stop8h 43m
American Airlines
Deal found 2/15$344
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:18 pm
CLT
-
MSO
1 stop8h 19m
Delta
Sun 5/175:15 am
MSO
-
CLT
1 stop9h 13m
Delta
Deal found 2/16$349
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:18 pm
CLT
-
MSO
1 stop8h 19m
Delta
Wed 6/106:10 pm
MSO
-
CLT
2 stops12h 37m
Delta
Deal found 2/16$354

Find flight deals from South Carolina to Missoula

Keep the following information in mind while searching for South Carolina to Missoula flight deals. Data was last updated February 18, 2026.

Round-trip from

$309
(Delta)

One-way from

$165
(United Airlines)
From South Carolina to Missoula Johnson-Bell Field
Search Deals
One-way flight from South Carolina to Missoula Johnson-Bell Field
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from South Carolina to Missoula that are best for you.

Fly from

South Carolina

Fly to

Missoula

Route

Depart

Return

Price

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Tue 4/28

8:06 am-1:32 pm

1 stop7h 26m

Missoula Johnson-Bell Field

Tue 5/5

2:37 pm-10:50 pm

1 stop6h 13m

$309

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Fri 5/29

7:09 pm-11:37 pm

1 stop6h 28m

Missoula Johnson-Bell Field

Fri 6/5

3:30 pm-11:55 pm

1 stop6h 25m

$309

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Thu 5/21

5:18 pm-11:37 pm

1 stop8h 19m

Missoula Johnson-Bell Field

Mon 5/25

5:15 am-4:28 pm

1 stop9h 13m

$309

CharlotteMissoula

CLT - MSO

CLTMSO

Charlotte Douglas

Thu 6/4

7:09 pm-11:37 pm

1 stop6h 28m

Missoula Johnson-Bell Field

Tue 6/9

6:10 pm-8:47 am

2 stops12h 37m

$314

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Fri 3/13

4:00 pm-9:57 pm

1 stop7h 57m

Missoula Johnson-Bell Field

Tue 3/17

6:15 am-9:16 pm

2 stops13h 01m

$334

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Tue 3/3

7:10 am-12:50 pm

1 stop7h 40m

Missoula Johnson-Bell Field

Sat 3/7

1:20 pm-11:51 pm

2 stops8h 31m

$394

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Fri 3/13

6:32 pm-12:21 pm

1 stop19h 49m

Missoula Johnson-Bell Field

Tue 3/17

1:39 pm-5:53 pm

1 stop26h 14m

$404

CharlestonMissoula

CHS - MSO

CHSMSO

Charleston

Wed 3/11

3:55 pm-9:57 pm

1 stop8h 02m

Missoula Johnson-Bell Field

Wed 3/18

6:15 am-2:59 pm

1 stop6h 44m

$404

AugustaMissoula

AGS - MSO

AGSMSO

Augusta Bush Field

Tue 8/11

12:55 pm-11:28 pm

2 stops12h 33m

Missoula Johnson-Bell Field

Mon 8/17

1:51 pm-10:43 pm

1 stop6h 52m

$459

AugustaMissoula

AGS - MSO

AGSMSO

Augusta Bush Field

Tue 8/11

12:55 pm-11:28 pm

2 stops12h 33m

Missoula Johnson-Bell Field

Sat 8/15

1:51 pm-10:43 pm

1 stop6h 52m

$459

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/16

Showing 1-10 of 47 results
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Best time to book a flight from South Carolina to Missoula

Have a flexible travel schedule? Discover the best time to fly to Missoula from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missoula

What is the cheapest time of day to fly from SC to MSO?

Find hourly flight availability from South Carolina to Missoula. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 18, 2026.

One of the essential ways to save on airfare from South Carolina to Missoula is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 35% on airfare.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Missoula from South Carolina?

    For a flight from South Carolina to Missoula, you will be flying into Johnson-Bell Field. Missoula Johnson-Bell Field (MSO) is just 5.5 mi from the center of the city.

  • How long is the flight from South Carolina to Missoula?

    United Airlines, Delta, and American Airlines can get you from South Carolina to Missoula in just under 6h 28m. Your travel time can differ by up to 1h 12m. There are 1887 mi between South Carolina and Missoula. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Missoula?

    When deciding which route to take from South Carolina to Missoula consider Charlotte Douglas - Missoula Johnson-Bell Field, Charleston - Missoula Johnson-Bell Field or Greenville - Missoula Johnson-Bell Field as they are the most popular.

  • Can I find deals for flights from South Carolina to Missoula that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missoula flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missoula?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missoula.

  • Can I find deals for business class flights from South Carolina to Missoula?

    Yes. Cheapflights offers flight deals from South Carolina to Missoula by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Missoula

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Missoula

Discover the top 2 airlines that operate flights from South Carolina to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$530FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$358Average$542FlexibilityNo cancel feeOn-time69%

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