$228+ Cheap flights from Missoula (MSO) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missoula to South CarolinaExplore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop7h 34m
Sat 10/312:40 pm -
1 stop7h 14m
Deal found 9/9![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop7h 34m
Fri 10/307:04 am -
2 stops12h 39m
Deal found 9/9![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops11h 14m
Sun 11/17:04 am -
2 stops12h 41m
Deal found 9/9![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:30 am -
1 stop9h 04m
Mon 11/25:44 pm -
1 stop7h 07m
Deal found 9/9![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:38 am -
1 stop8h 53m
Mon 9/286:45 am -
1 stop6h 39m
Deal found 9/6![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops9h 25m
Mon 11/22:23 pm -
2 stops10h 28m
Deal found 9/6![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:35 pm -
1 stop6h 05m
Mon 9/287:16 pm -
1 stop6h 26m
Deal found 9/9![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:28 pm -
1 stop6h 47m
Wed 10/148:46 am -
1 stop6h 46m
Deal found 9/7![United Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:40 pm -
1 stop6h 49m
Sat 9/2612:30 pm -
2 stops11h 02m
Deal found 9/9![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am -
1 stop9h 10m
Sat 9/265:13 pm -
1 stop8h 29m
Deal found 9/9![Delta logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:06 pm -
2 stops20h 33m
Thu 12/2412:45 pm -
2 stops10h 02m
Deal found 9/9![American Airlines logo]()
$766
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:50 am -
2 stops13h 54m
Sat 12/1911:08 am -
2 stops13h 25m
Deal found 9/8![American Airlines logo]()
$810
Best flights from Missoula to South CarolinaDiscover carefully curated flight deals from Missoula to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Missoula to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:30 am -
1 stop9h 04m
Mon 11/22:23 pm -
2 stops10h 28m
Deal found 9/9![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:40 pm -
1 stop6h 49m
Sat 9/2612:30 pm -
2 stops11h 02m
Deal found 9/9![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:30 am -
1 stop9h 04m
Sun 11/17:04 am -
2 stops12h 41m
Deal found 9/9![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:30 am -
1 stop9h 04m
Sat 10/316:02 am -
2 stops15h 52m
Deal found 9/9![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops10h 01m
Thu 10/295:44 pm -
1 stop8h 47m
Deal found 9/9![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:15 am -
1 stop6h 54m
Tue 1/264:05 pm -
1 stop7h 21m
Deal found 9/10![United Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/201:42 pm -
2 stops19h 57m
Sun 12/276:18 pm -
2 stops20h 54m
Deal found 9/9![American Airlines logo]()
$939
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops9h 25m
Sat 10/312:40 pm -
1 stop7h 14m
Deal found 9/6![Delta logo]()
$384
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:33 am -
1 stop7h 52m
Sun 11/15:44 pm -
1 stop7h 07m
Deal found 9/6![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:35 pm -
1 stop6h 05m
Mon 9/287:16 pm -
1 stop6h 26m
Deal found 9/9![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/262:27 pm -
2 stops18h 20m
Sat 1/3011:28 am -
2 stops11h 58m
Deal found 9/10![United Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:50 am -
2 stops13h 54m
Sat 12/197:25 am -
1 stop17h 08m
Deal found 9/8![American Airlines logo]()
$1,014
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:50 am -
1 stop13h 44m
Thu 12/2412:45 pm -
2 stops10h 02m
Deal found 9/9![American Airlines logo]()
$1,109
Last-minute flights from Missoula to South CarolinaDiscover last-minute flight deals from Missoula to South Carolina. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to South Carolina. Data last updated September 11, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:40 pm -
1 stop6h 49m
Sat 9/2612:30 pm -
2 stops11h 02m
Deal found 9/9![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am -
1 stop9h 10m
Sat 9/265:13 pm -
1 stop8h 29m
Deal found 9/9![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:38 am -
1 stop8h 53m
Mon 9/286:45 am -
1 stop6h 39m
Deal found 9/6![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:35 pm -
1 stop6h 05m
Mon 9/287:16 pm -
1 stop6h 26m
Deal found 9/9![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:28 pm -
1 stop6h 47m
Wed 10/148:46 am -
1 stop6h 46m
Deal found 9/7![United Airlines logo]()
$432
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop7h 34m
Sun 11/15:44 pm -
1 stop7h 07m
Deal found 9/9![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop7h 34m
Fri 10/307:04 am -
2 stops12h 39m
Deal found 9/9![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops9h 25m
Sat 10/312:40 pm -
1 stop7h 14m
Deal found 9/6![Delta logo]()
$384
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop7h 34m
Thu 10/295:44 pm -
1 stop8h 47m
Deal found 9/6![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops9h 25m
Mon 11/22:23 pm -
2 stops10h 28m
Deal found 9/6![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:30 am -
1 stop9h 04m
Sun 11/15:44 pm -
1 stop7h 07m
Deal found 9/9![Delta logo]()
$389
One-way flights from Missoula to South CarolinaSearch for one-way flight options from Missoula to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Missoula to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:23 pm -
2 stops12h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$228
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:35 pm -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:05 pm -
3 stops39h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$253
This deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:48 pm -
1 stop8h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$268
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:38 am -
1 stop8h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:49 pm -
2 stops34h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop5h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$300
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:17 pm -
2 stops12h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:15 pm -
2 stops15h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:15 pm -
2 stops15h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:17 am -
3 stops44h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1111:37 am -
3 stops44h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$378
Find flight deals from Missoula to South Carolina
Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (Delta) |
One-way from | $228 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Tue 9/29
3:35 pm-11:40 pm
1 stop6h 05m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$252
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Tue 10/20
1:48 pm-11:59 pm
1 stop8h 11m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$268
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Mon 10/19
10:38 am-9:31 pm
1 stop8h 53m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$271
Quickest round-trip
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Sun 10/4
6:00 am-1:59 pm
1 stop5h 59m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$300
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Tue 9/29
12:21 pm-9:15 pm
1 stop6h 54m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$312
MissoulaMyrtle Beach
MSO Missoula Johnson-Bell Field - MYR Myrtle Beach Intl
MSOMYR
Missoula Johnson-Bell Field
Fri 10/16
4:15 pm-9:44 am
2 stops15h 29m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$330
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Tue 10/6
12:28 pm-9:15 pm
1 stop6h 47m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$340
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Tue 9/29
7:00 am-9:42 pm
2 stops12h 42m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$348
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Sun 10/25
5:30 am-4:34 pm
1 stop9h 04m
Charlotte Douglas
Mon 11/2
2:23 pm-10:51 pm
2 stops10h 28m
$364
MissoulaCharlotte
MSO Missoula Johnson-Bell Field - CLT Charlotte Douglas
MSOCLT
Missoula Johnson-Bell Field
Sun 10/25
5:30 am-4:34 pm
1 stop9h 04m
Charlotte Douglas
Sun 11/1
7:04 am-5:45 pm
2 stops12h 41m
$364
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Missoula to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missoula to South Carolina
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What is the cheapest month to book a flight from Missoula to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Missoula to South Carolina (average of $379). Flying from Missoula to South Carolina in May is currently the most expensive (average of $986). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 11, 2026.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Food
6.7
Overall
7.4
Boarding
7.7
Crew
8.1
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Food
6.7
Overall
7.4
Boarding
7.7
Crew
8.1
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Food
6.7
Overall
7.4
Boarding
7.7
Crew
8.1
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missoula to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Missoula and South Carolina flights
Browse other Missoula and South Carolina flight options. Last updated on September 11, 2026.
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Missoula to South Carolina flights
Consider these flights traveling from Missoula to South Carolina.
Top 2 airlines flying from Missoula to South Carolina
Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$337 | Average$484 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$356 | Average$560 | FlexibilityNo cancel fee | On-time69% |