South Carolina

$256+ Cheap flights from Missoula (MSO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
mai 24 — mai 311
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Cheap flight deals from Missoula to South Carolina

Cheapest flights from Missoula to South Carolina
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 24, 2026.

This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/45:35 am
MSO
-
CLT
1 stop9h 07m
Delta
lun. 8/105:25 pm
CLT
-
MSO
1 stop8h 59m
Delta
Deal found 4/21$369
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/2212:34 pm
MSO
-
CLT
1 stop6h 55m
United Airlines
sam. 5/309:55 am
CLT
-
MSO
2 stops13h 39m
United Airlines
Deal found 4/21$374
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/272:18 pm
MSO
-
MYR
1 stop7h 33m
American Airlines
sam. 5/306:33 am
MYR
-
MSO
1 stop8h 55m
American Airlines
Deal found 4/19$389
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/55:20 am
MSO
-
CLT
2 stops10h 49m
Delta
lun. 5/117:19 pm
CLT
-
MSO
1 stop6h 21m
Delta
Deal found 4/21$399
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 8/55:35 am
MSO
-
CLT
1 stop9h 07m
Delta
mer. 8/125:25 pm
CLT
-
MSO
1 stop8h 59m
Delta
Deal found 4/21$421
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 8/55:35 am
MSO
-
CLT
1 stop9h 07m
Delta
mar. 8/113:00 pm
CLT
-
MSO
2 stops11h 24m
Delta
Deal found 4/21$426
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/304:44 pm
MSO
-
CLT
1 stop10h 25m
American Airlines
sam. 7/47:05 am
CLT
-
MSO
1 stop11h 06m
American Airlines
Deal found 4/21$430
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/196:15 am
MSO
-
CLT
2 stops13h 24m
United Airlines
sam. 5/234:08 pm
CLT
-
MSO
1 stop7h 26m
United Airlines
Deal found 4/22$444
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 9/212:40 pm
MSO
-
CLT
1 stop6h 50m
United Airlines
sam. 9/56:15 am
CLT
-
MSO
1 stop7h 19m
United Airlines
Deal found 4/19$469
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 4/235:20 am
MSO
-
CLT
1 stop8h 44m
Delta
dim. 4/265:15 pm
CLT
-
MSO
1 stop9h 01m
Delta
Deal found 4/20$473
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/274:19 pm
MSO
-
MYR
2 stops15h 40m
United Airlines
sam. 5/3011:25 am
MYR
-
MSO
2 stops13h 13m
United Airlines
Deal found 4/19$474
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/282:18 pm
MSO
-
MYR
1 stop7h 33m
American Airlines
dim. 5/316:33 am
MYR
-
MSO
1 stop8h 55m
American Airlines
Deal found 4/19$490

Find flight deals from Missoula to South Carolina

Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated avril 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(Delta)

One-way from

$256
(Kiwi.com)
Provider with most accurate pricing for Missoula Johnson-Bell Field-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Missoula Johnson-Bell Field-Myrtle Beach Intl flights.
From Missoula Johnson-Bell Field to South Carolina
One-way flight from Missoula Johnson-Bell Field to South Carolina

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated avril 24, 2026.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

ven. 7/31

5:35 am-4:42 pm

1 stop9h 07m

Charlotte Douglas

lun. 8/10

5:25 pm-12:24 am

1 stop8h 59m

$369

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

mer. 5/27

2:18 pm-11:51 pm

1 stop7h 33m

Myrtle Beach Intl

sam. 5/30

6:33 am-1:28 pm

1 stop8h 55m

$389

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mar. 5/5

5:20 am-6:09 pm

2 stops10h 49m

Charlotte Douglas

lun. 5/11

7:19 pm-11:40 pm

1 stop6h 21m

$399

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mer. 9/2

12:40 pm-9:30 pm

1 stop6h 50m

Charlotte Douglas

sam. 9/5

6:15 am-11:34 am

1 stop7h 19m

$469

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mar. 8/4

6:27 pm-8:52 am

2 stops12h 25m

Charlotte Douglas

mer. 8/12

5:25 pm-12:24 am

1 stop8h 59m

$479

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mar. 5/19

6:15 am-3:15 pm

1 stop7h 00m

Charlotte Douglas

sam. 5/23

4:08 pm-9:34 pm

1 stop7h 26m

$487

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

sam. 5/30

4:44 pm-8:41 am

2 stops13h 57m

Myrtle Beach Intl

jeu. 6/4

4:38 pm-10:38 pm

1 stop8h 00m

$506
Quickest round-trip

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

mar. 6/9

2:26 pm-11:08 pm

1 stop6h 42m

Charlotte Douglas

jeu. 6/11

6:15 am-11:32 am

1 stop7h 17m

$516

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

lun. 5/4

3:55 pm-10:23 am

2 stops16h 28m

Charlotte Douglas

ven. 5/8

3:23 pm-12:28 pm

2 stops23h 05m

$539

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

sam. 5/30

1:14 pm-11:58 pm

2 stops8h 44m

Myrtle Beach Intl

jeu. 6/4

3:21 pm-12:22 am

2 stops11h 01m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/19

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Missoula to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated avril 24, 2026.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Missoula to South Carolina?

    Missoula Johnson-Bell Field (MSO), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Missoula to South Carolina.

  • How long is the flight from Missoula to South Carolina?

    Airlines like Delta, United Airlines, and American Airlines fly from Missoula to South Carolina in about 6h 50m. The time it takes to get you to your destination can typically vary by up to 7h 07m. Missoula and South Carolina are separated by a distance of 1887 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missoula to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missoula to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to South Carolina.

  • Can I find deals for business class flights from Missoula to South Carolina?

    Yes. Cheapflights offers flight deals from Missoula to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Missoula to South Carolina

Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated avril 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$476FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$312Average$521FlexibilityNo cancel feeOn-time69%

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