South Carolina

$246+ Cheap flights from Missoula (MSO) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
Jul 11 — Jul 181
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Cheap flight deals from Missoula to South Carolina

Cheapest flights from Missoula to South Carolina
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.

This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
MSO
-
CLT
1 stop5h 57m
Delta
Mon 8/175:52 pm
CLT
-
MSO
1 stop8h 26m
Delta
Deal found 6/10$349
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
MSO
-
CLT
1 stop5h 57m
Delta
Wed 8/197:18 pm
CLT
-
MSO
1 stop6h 29m
Delta
Deal found 6/10$384
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:25 pm
MSO
-
CLT
1 stop8h 23m
American Airlines
Tue 8/187:35 am
CLT
-
MSO
1 stop7h 00m
American Airlines
Deal found 6/10$411
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:05 am
MSO
-
CLT
1 stop7h 07m
United Airlines
Tue 7/71:06 pm
CLT
-
MSO
2 stops12h 50m
United Airlines
Deal found 6/8$436
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am
MSO
-
CLT
1 stop6h 59m
United Airlines
Tue 10/278:15 am
CLT
-
MSO
1 stop9h 55m
United Airlines
Deal found 6/7$449
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:36 pm
MSO
-
CLT
1 stop6h 01m
Delta
Mon 8/177:18 pm
CLT
-
MSO
1 stop6h 29m
Delta
Deal found 6/9$464
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:34 pm
MSO
-
CLT
1 stop6h 55m
United Airlines
Tue 7/71:06 pm
CLT
-
MSO
2 stops12h 50m
United Airlines
Deal found 6/8$467
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:36 pm
MSO
-
CLT
1 stop6h 01m
Delta
Tue 8/182:38 pm
CLT
-
MSO
2 stops11h 09m
Delta
Deal found 6/9$469
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am
MSO
-
MYR
2 stops33h 34m
United Airlines
Tue 11/311:25 am
MYR
-
MSO
2 stops12h 01m
United Airlines
Deal found 6/9$664
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:55 am
MSO
-
MYR
2 stops13h 55m
Delta
Tue 7/215:30 pm
MYR
-
MSO
2 stops8h 58m
Delta
Deal found 6/8$698
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:55 am
MSO
-
MYR
2 stops13h 55m
Delta
Sat 7/185:45 pm
MYR
-
MSO
2 stops31h 59m
Delta
Deal found 6/8$820
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:55 am
MSO
-
MYR
2 stops13h 55m
Delta
Fri 7/175:30 pm
MYR
-
MSO
2 stops8h 58m
Delta
Deal found 6/8$837

Find flight deals from Missoula to South Carolina

Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated June 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(Delta)

One-way from

$246
(Delta)
Provider with most accurate pricing for Missoula Johnson-Bell Field-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Missoula Johnson-Bell Field-Myrtle Beach Intl flights.
From Missoula Johnson-Bell Field to South Carolina
One-way flight from Missoula Johnson-Bell Field to South Carolina

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 8/12

6:00 am-1:57 pm

1 stop5h 57m

Charlotte Douglas

Mon 8/17

2:51 pm-12:18 am

2 stops11h 27m

$354
Quickest round-trip

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Wed 8/12

6:00 am-1:57 pm

1 stop5h 57m

Charlotte Douglas

Wed 8/19

7:18 pm-11:47 pm

1 stop6h 29m

$384

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Tue 10/27

2:27 pm-10:47 pm

1 stop6h 20m

Charlotte Douglas

Sat 10/31

4:05 pm-9:26 pm

1 stop7h 21m

$449

MissoulaCharlotte

MSO - CLT

MSOCLT

Missoula Johnson-Bell Field

Sat 10/24

6:15 am-3:14 pm

1 stop6h 59m

Charlotte Douglas

Tue 10/27

8:15 am-4:10 pm

1 stop9h 55m

$449

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Sat 10/31

6:15 am-5:49 pm

2 stops33h 34m

Myrtle Beach Intl

Tue 11/3

11:25 am-9:26 pm

2 stops12h 01m

$664

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Tue 6/30

5:55 am-9:50 pm

2 stops13h 55m

Myrtle Beach Intl

Tue 7/21

5:30 pm-12:28 am

2 stops8h 58m

$698

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Tue 6/30

5:55 am-9:50 pm

2 stops13h 55m

Myrtle Beach Intl

Sat 7/18

5:45 pm-11:44 pm

2 stops31h 59m

$820

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Tue 6/30

5:55 am-9:50 pm

2 stops13h 55m

Myrtle Beach Intl

Fri 7/17

5:30 pm-12:28 am

2 stops8h 58m

$837

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Tue 6/30

5:55 am-9:50 pm

2 stops13h 55m

Myrtle Beach Intl

Thu 7/16

7:59 pm-12:28 am

2 stops30h 29m

$890

MissoulaMyrtle Beach

MSO - MYR

MSOMYR

Missoula Johnson-Bell Field

Tue 6/30

5:55 am-9:50 pm

2 stops13h 55m

Myrtle Beach Intl

Sun 7/19

5:30 pm-11:44 pm

1 stop8h 14m

$987

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/8

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Missoula to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 11, 2026.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.6

Overall

7.4

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Food

6.6

Overall

7.4

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Food

6.6

Overall

7.4

Entertainment

7.1

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Missoula to South Carolina?

    Missoula Johnson-Bell Field (MSO), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Missoula to South Carolina.

  • How long is the flight from Missoula to South Carolina?

    Airlines like Delta and United Airlines fly from Missoula to South Carolina in about 5h 57m. The time it takes to get you to your destination can typically vary by up to 1h 10m. Missoula and South Carolina are separated by a distance of 1887 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missoula to South Carolina that include hotel bookings?

    Yes. In addition to deals on Missoula to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to South Carolina.

  • Can I find deals for business class flights from Missoula to South Carolina?

    Yes. Cheapflights offers flight deals from Missoula to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Missoula to South Carolina

Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$449FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$312Average$507FlexibilityNo cancel feeOn-time69%

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