$200+ Cheap flights from Missoula (MSO) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — CHS
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missoula to South CarolinaExplore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Missoula to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:21 pm -
1 stop22h 34m
Tue 11/105:58 pm -
1 stop20h 24m
Deal found 10/22![Alaska Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
1 stop6h 53m
Wed 11/116:30 am -
2 stops11h 56m
Deal found 10/23![United Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:25 pm -
2 stops13h 00m
Tue 11/105:34 pm -
2 stops8h 46m
Deal found 10/22![Delta logo]()
$509
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:50 am -
2 stops13h 54m
Wed 11/111:52 pm -
2 stops24h 44m
Deal found 10/23![American Airlines logo]()
$741
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:06 pm -
1 stop8h 49m
Fri 11/64:44 pm -
1 stop21h 52m
Deal found 10/22![American Airlines logo]()
$813
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:37 pm -
3 stops17h 44m
Wed 11/1111:27 am -
2 stops12h 20m
Deal found 10/23![United Airlines logo]()
$935
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:33 am -
2 stops11h 41m
Fri 11/65:40 am -
2 stops8h 54m
Deal found 10/24![Delta logo]()
$945
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:30 am -
2 stops10h 35m
Thu 12/310:52 am -
2 stops11h 10m
Deal found 10/21![Delta logo]()
$964
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am -
2 stops12h 47m
Fri 11/610:16 am -
2 stops13h 31m
Deal found 10/23![United Airlines logo]()
$993
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 am -
1 stop9h 32m
Mon 12/286:44 pm -
1 stop20h 14m
Deal found 10/22![American Airlines logo]()
$1,010
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:28 pm -
1 stop8h 27m
Mon 12/288:34 pm -
2 stops18h 24m
Deal found 10/24![American Airlines logo]()
$1,046
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:23 pm -
2 stops13h 57m
Mon 12/284:31 pm -
2 stops10h 11m
Deal found 10/22![Delta logo]()
$1,132
Best flights from Missoula to South CarolinaDiscover carefully curated flight deals from Missoula to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Missoula to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Alaska Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/247:41 am -
1 stop7h 38m
Wed 1/276:22 pm -
1 stop20h 00m
Deal found 10/23![Alaska Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/248:25 am -
1 stop6h 37m
Wed 1/2711:00 am -
2 stops10h 55m
Deal found 10/26![Delta logo]()
$404
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:10 am -
1 stop6h 50m
Wed 1/2712:50 pm -
2 stops11h 02m
Deal found 10/23![United Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/101:08 pm -
1 stop8h 00m
Sat 4/175:13 am -
2 stops9h 25m
Deal found 10/24![American Airlines logo]()
$450
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/106:10 pm -
2 stops13h 32m
Sat 4/174:30 pm -
2 stops10h 01m
Deal found 10/22![Delta logo]()
$439
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:21 pm -
1 stop22h 34m
Tue 11/105:58 pm -
1 stop20h 24m
Deal found 10/22![Alaska Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
1 stop6h 53m
Wed 11/116:30 am -
2 stops11h 56m
Deal found 10/23![United Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:18 pm -
2 stops12h 25m
Fri 11/133:23 pm -
1 stop6h 34m
Deal found 10/25![Delta logo]()
$484
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:10 pm -
2 stops13h 15m
Thu 4/85:40 am -
2 stops8h 56m
Deal found 10/21![Delta logo]()
$539
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/269:45 am -
2 stops30h 03m
Sat 1/3011:27 am -
2 stops12h 25m
Deal found 10/22![United Airlines logo]()
$663
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:50 am -
2 stops13h 54m
Wed 11/111:52 pm -
2 stops24h 44m
Deal found 10/23![American Airlines logo]()
$741
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:30 am -
2 stops10h 35m
Thu 12/310:52 am -
2 stops11h 10m
Deal found 10/21![Delta logo]()
$964
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/181:23 pm -
1 stop8h 32m
Mon 12/288:34 pm -
2 stops18h 24m
Deal found 10/24![American Airlines logo]()
$1,179
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:15 am -
2 stops8h 45m
Thu 4/810:20 am -
3 stops13h 06m
Deal found 10/21![United Airlines logo]()
$1,156
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:00 am -
1 stop8h 50m
Sun 12/278:34 pm -
2 stops18h 24m
Deal found 10/21![American Airlines logo]()
$1,287
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop7h 16m
Sun 12/274:17 pm -
1 stop7h 23m
Deal found 10/23![United Airlines logo]()
$1,405
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
2 stops13h 08m
Sun 12/276:15 am -
2 stops9h 18m
Deal found 10/25![United Airlines logo]()
$1,444
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop6h 47m
Sat 11/286:00 am -
2 stops9h 31m
Deal found 10/21![United Airlines logo]()
$1,447
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:50 am -
1 stop7h 37m
Sun 11/296:27 pm -
1 stop20h 21m
Deal found 10/21![American Airlines logo]()
$1,757
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:30 am -
2 stops8h 15m
Sat 11/287:20 am -
2 stops12h 18m
Deal found 10/21![Delta logo]()
$1,730
This Alaska Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:00 am -
2 stops12h 56m
Sun 12/2711:43 am -
3 stops14h 16m
Deal found 10/23![Alaska Airlines logo]()
$2,665
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop6h 47m
Sun 11/296:20 am -
2 stops9h 11m
Deal found 10/21![United Airlines logo]()
$1,701
This Travelocity deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:22 am -
2 stops13h 41m
Sat 11/2811:37 am -
3 stops13h 23m
Deal found 10/21![Alaska Airlines logo]()
$3,843
This Travelocity deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:04 pm -
3 stops20h 03m
Sun 11/2911:37 am -
3 stops13h 23m
Deal found 10/21![Alaska Airlines logo]()
$3,948
Last-minute flights from Missoula to South CarolinaDiscover last-minute flight deals from Missoula to South Carolina. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to South Carolina. Data last updated October 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:06 pm -
1 stop8h 49m
Fri 11/64:44 pm -
1 stop21h 52m
Deal found 10/22![American Airlines logo]()
$813
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:33 am -
2 stops11h 41m
Fri 11/65:40 am -
2 stops8h 54m
Deal found 10/25![Delta logo]()
$945
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am -
2 stops12h 47m
Fri 11/610:16 am -
2 stops13h 31m
Deal found 10/23![United Airlines logo]()
$993
This Alaska Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:21 pm -
1 stop22h 34m
Tue 11/105:58 pm -
1 stop20h 24m
Deal found 10/22![Alaska Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:25 pm -
2 stops13h 00m
Tue 11/105:34 pm -
2 stops8h 46m
Deal found 10/22![Delta logo]()
$509
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
1 stop6h 53m
Wed 11/116:30 am -
2 stops11h 56m
Deal found 10/23![United Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:50 am -
2 stops13h 54m
Wed 11/111:52 pm -
2 stops24h 44m
Deal found 10/23![American Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:37 pm -
3 stops17h 44m
Wed 11/1111:27 am -
2 stops12h 20m
Deal found 10/23![United Airlines logo]()
$935
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop6h 47m
Sat 11/286:00 am -
2 stops9h 31m
Deal found 10/21![United Airlines logo]()
$1,447
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop6h 47m
Sun 11/296:20 am -
2 stops9h 11m
Deal found 10/21![United Airlines logo]()
$1,701
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:50 am -
2 stops10h 56m
Sun 11/298:35 pm -
2 stops18h 13m
Deal found 10/21![American Airlines logo]()
$1,717
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:30 am -
2 stops10h 35m
Thu 12/310:52 am -
2 stops11h 10m
Deal found 10/21![Delta logo]()
$964
One-way flights from Missoula to South CarolinaSearch for one-way flight options from Missoula to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Missoula to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:06 pm -
1 stop9h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![American Airlines logo]()
$200
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:25 pm -
2 stops13h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$205
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:18 pm -
2 stops13h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/181:23 pm -
1 stop8h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$280
This Priceline deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:00 am -
1 stop8h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Alaska Airlines logo]()
$286
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:18 pm -
2 stops13h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$305
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:25 pm -
2 stops12h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$318
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:25 am -
2 stops12h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:15 pm -
3 stops40h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:19 pm -
3 stops57h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$347
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:18 pm -
2 stops13h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Delta logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:28 pm -
3 stops36h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$380
Find flight deals from Missoula to South Carolina
Keep the following information in mind while searching for Missoula to South Carolina flight deals. Data was last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $399 (Alaska Airlines) |
One-way from | $200 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Missoula to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaCharleston
MSO Missoula Johnson-Bell Field - CHS Charleston
MSOCHS
Missoula Johnson-Bell Field
Fri 12/18
6:25 pm-10:20 am
2 stops13h 55m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$205
MissoulaMyrtle Beach
MSO Missoula Johnson-Bell Field - MYR Myrtle Beach Intl
MSOMYR
Missoula Johnson-Bell Field
Tue 11/10
6:18 pm-10:07 am
2 stops13h 49m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$277
MissoulaMyrtle Beach
MSO Missoula Johnson-Bell Field - MYR Myrtle Beach Intl
MSOMYR
Missoula Johnson-Bell Field
Fri 11/13
6:18 pm-10:07 am
2 stops13h 49m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$277
MissoulaCharleston
MSO Missoula Johnson-Bell Field - CHS Charleston
MSOCHS
Missoula Johnson-Bell Field
Fri 12/18
1:23 pm-12:20 am
1 stop8h 57m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$280
MissoulaMyrtle Beach
MSO Missoula Johnson-Bell Field - MYR Myrtle Beach Intl
MSOMYR
Missoula Johnson-Bell Field
Mon 11/9
6:18 pm-10:07 am
2 stops13h 49m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$305
MissoulaGreenville
MSO Missoula Johnson-Bell Field - GSP Greenville
MSOGSP
Missoula Johnson-Bell Field
Fri 12/18
6:25 pm-9:24 am
2 stops12h 59m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$318
MissoulaCharleston
MSO Missoula Johnson-Bell Field - CHS Charleston
MSOCHS
Missoula Johnson-Bell Field
Thu 12/17
7:28 pm-9:48 am
3 stops36h 20m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$380
MissoulaCharleston
MSO Missoula Johnson-Bell Field - CHS Charleston
MSOCHS
Missoula Johnson-Bell Field
Sun 1/24
7:41 am-5:19 pm
1 stop7h 38m
Charleston
Wed 1/27
6:22 pm-12:22 pm
1 stop20h 00m
$399
MissoulaGreenville
MSO Missoula Johnson-Bell Field - GSP Greenville
MSOGSP
Missoula Johnson-Bell Field
Fri 12/18
10:19 pm-7:53 am
3 stops31h 34m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$403
MissoulaCharleston
MSO Missoula Johnson-Bell Field - CHS Charleston
MSOCHS
Missoula Johnson-Bell Field
Sun 1/24
8:25 am-5:02 pm
1 stop6h 37m
Charleston
Wed 1/27
11:00 am-7:55 pm
2 stops10h 55m
$404
Showing 1-10 of 38 resultsSorted by cheapest first
Best time to book a flight from Missoula to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Missoula with our price prediction graph.
MSO-CHS
MSO-MYR
MSO-CAE
MSO-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missoula to South Carolina
MSO-USSC
MSO-CHS
MSO-MYR
MSO-CAE
MSO-GSP
What is the cheapest month to book a flight from Missoula to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Missoula to South Carolina (average of $379). Flying from Missoula to South Carolina in May is currently the most expensive (average of $986). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 26, 2026.
See what other customers who have flown with United Airlines and American Airlines from Missoula to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.3
Food
6.7
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Overall
7.3
Food
6.7
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Overall
7.3
Food
6.7
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Missoula to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missoula to South Carolina
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Complete your trip
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Missoula and South Carolina flights
Browse other Missoula and South Carolina flight options. Last updated on October 26, 2026.
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Missoula to South Carolina flights
Consider these flights traveling from Missoula to South Carolina.
Top 2 airlines flying from Missoula to South Carolina
Discover the top 2 airlines that operate flights from Missoula to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$337 | Average$480 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$379 | Average$628 | FlexibilityNo cancel fee | On-time69% |