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$149+ Cheap flights from Portland, ME (PWM) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — JAN
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Portland to Mississippi

Keep the following information in mind while searching for Portland to Mississippi flight deals. Data was last updated July 30, 2025.

Round-trip from

$276
(Delta)

One-way from

$149
(American Airlines)
From Portland to Mississippi
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One-way flight from Portland to Mississippi
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Find flight deals from Portland to Mississippi

Cheapest flights from Portland to Mississippi
Explore the most affordable flight options available from Portland to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/34:50 pmPWM - MOB
2 stops7h 26mDelta
Sat 9/66:00 amMOB - PWM
1 stop5h 29mDelta
Deal found 7/27$274
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:00 amPWM - BTR
1 stop7h 53mDelta
Tue 9/96:00 amBTR - PWM
2 stops9h 10mDelta
Deal found 7/29$276
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/212:48 pmPWM - MEM
1 stop7h 15mAmerican Airlines
Wed 8/278:50 amMEM - PWM
1 stop5h 12mAmerican Airlines
Deal found 7/29$296
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:00 amPWM - MEM
1 stop6h 41mDelta
Sun 8/244:50 pmMEM - PWM
1 stop6h 13mDelta
Deal found 7/29$297
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:31 amPWM - GPT
2 stops16h 07mDelta
Tue 8/265:00 pmGPT - PWM
1 stop6h 03mDelta
Deal found 7/27$312
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:41 pmPWM - MEM
1 stop6h 23mUnited Airlines
Sun 10/197:30 amMEM - PWM
1 stop6h 03mUnited Airlines
Deal found 7/29$328
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/238:00 amPWM - GPT
2 stops11h 20mAmerican Airlines
Tue 8/266:30 amGPT - PWM
2 stops8h 00mAmerican Airlines
Deal found 7/27$384
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/133:53 pmPWM - BTR
1 stop8h 08mAmerican Airlines
Sun 8/176:59 amBTR - PWM
1 stop5h 37mAmerican Airlines
Deal found 7/29$421
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:00 amPWM - MOB
2 stops11h 07mUnited Airlines
Tue 11/1111:35 amMOB - PWM
2 stops10h 42mUnited Airlines
Deal found 7/28$467
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:41 amPWM - MOB
2 stops12h 06mAmerican Airlines
Wed 11/126:33 amMOB - PWM
2 stops9h 06mAmerican Airlines
Deal found 7/28$472
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:35 amPWM - GPT
2 stops11h 39mUnited Airlines
Sun 8/177:00 amGPT - PWM
2 stops10h 26mUnited Airlines
Deal found 7/29$555
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/288:25 amPWM - MEM
2 stops10h 20mSouthwest
Fri 8/293:35 pmMEM - PWM
2 stops6h 45mSouthwest
Deal found 7/28$564

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Portland to Mississippi that are best for you.

Fly from

Portland

Fly to

Mississippi

Route

Depart

Return

Price

PortlandMobile

PWM - MOB

PWMMOB

Portland

Wed 9/3

4:50 pm-11:16 pm

2 stops7h 26m

Mobile

Sat 9/6

6:00 am-12:29 pm

1 stop5h 29m

$274

PortlandBaton Rouge

PWM - BTR

PWMBTR

Portland

Sat 9/6

6:00 am-12:53 pm

1 stop7h 53m

Baton Rouge Ryan

Tue 9/9

6:00 am-4:10 pm

2 stops9h 10m

$276

PortlandMemphis

PWM - MEM

PWMMEM

Portland

Thu 8/21

2:48 pm-9:03 pm

1 stop7h 15m

Memphis

Wed 8/27

8:50 am-3:02 pm

1 stop5h 12m

$296

PortlandMemphis

PWM - MEM

PWMMEM

Portland

Wed 8/20

6:00 am-11:41 am

1 stop6h 41m

Memphis

Sun 8/24

4:50 pm-12:03 am

1 stop6h 13m

$297

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 8/23

6:31 am-9:38 pm

2 stops16h 07m

Gulfport Biloxi Regional

Tue 8/26

5:00 pm-12:03 am

1 stop6h 03m

$312

PortlandMemphis

PWM - MEM

PWMMEM

Portland

Thu 10/16

5:41 pm-11:04 pm

1 stop6h 23m

Memphis

Sun 10/19

7:30 am-2:33 pm

1 stop6h 03m

$328

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 8/23

8:00 am-6:20 pm

2 stops11h 20m

Gulfport Biloxi Regional

Tue 8/26

6:30 am-3:30 pm

2 stops8h 00m

$384

PortlandBaton Rouge

PWM - BTR

PWMBTR

Portland

Wed 8/13

3:53 pm-11:01 pm

1 stop8h 08m

Baton Rouge Ryan

Sun 8/17

6:59 am-1:36 pm

1 stop5h 37m

$421

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 8/13

5:35 am-4:14 pm

2 stops11h 39m

Gulfport Biloxi Regional

Sun 8/17

7:00 am-6:26 pm

2 stops10h 26m

$555

PortlandMemphis

PWM - MEM

PWMMEM

Portland

Thu 8/28

8:25 am-5:45 pm

2 stops10h 20m

Memphis

Fri 8/29

3:35 pm-11:20 pm

2 stops6h 45m

$564

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 19 results
1
2

Best time to book a flight from Portland to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Mississippi

What is the cheapest month to book a flight from Portland, Maine to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Mississippi (average of $371). Flying from Portland, Maine to Mississippi in March is currently the most expensive (average of $449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown Southwest, Delta, and Breeze Airways from Portland to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Breeze Airways
8.0
Very good
191 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Portland to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Mississippi?

    For a flight from Portland to Mississippi, you will be flying from Portland. Portland (PWM) is just 2.9 mi from the center of the city.

  • What are the cheapest airlines to fly from Portland, Maine to Mississippi one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $149. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Portland, Maine to Mississippi for a low price.

  • What are the most popular routes from Portland, Maine to Mississippi?

    Most travelers choose Portland - Memphis, Portland - Mobile or Portland - Gulfport Biloxi Regional when deciding on the best route from Portland, Maine to Mississippi.

  • Can I find deals for flights from Portland to Mississippi that include hotel bookings?

    Yes. In addition to deals on Portland to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Mississippi.

  • Can I find deals for business class flights from Portland to Mississippi?

    Yes. Cheapflights offers flight deals from Portland to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Mississippi (average of $371). Flying from Portland, Maine to Mississippi in March is currently the most expensive (average of $449). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Portland to Mississippi

Discover the top 2 airlines that operate flights from Portland to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$291Average$469FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$353Average$498FlexibilityNo cancel feeOn-time71%

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