$113+ Cheap flights from Knoxville (TYS) to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Jun 3 — Jun 101
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to MississippiExplore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
- MEM
1 stop21h 09m
Allegiant Air
Mon 5/188:05 am
MEM
- TYS
1 stop13h 19m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:03 pm
TYS
- MEM
1 stop19h 29m
Multiple Airlines
Fri 6/55:04 pm
MEM
- TYS
1 stop14h 31m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:55 pm
TYS
- MEM
2 stops23h 39m
Multiple Airlines
Mon 6/15:04 pm
MEM
- TYS
1 stop22h 11m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:06 pm
TYS
- MEM
1 stop18h 43m
Allegiant Air
Mon 7/204:49 pm
MEM
- TYS
1 stop22h 21m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 am
TYS
- MEM
1 stop11h 19m
Allegiant Air
Mon 5/188:05 am
MEM
- TYS
1 stop13h 19m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:05 pm
TYS
- MEM
1 stop18h 41m
Allegiant Air
Mon 6/85:04 pm
MEM
- TYS
1 stop22h 08m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
TYS
- MEM
2 stops11h 23m
Multiple Airlines
Mon 5/188:05 am
MEM
- TYS
1 stop13h 19m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:36 pm
TYS
- MEM
1 stop22h 58m
Allegiant Air
Mon 6/15:04 pm
MEM
- TYS
1 stop22h 11m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
TYS
- MEM
1 stop4h 55m
Southwest
Wed 6/39:45 am
MEM
- TYS
1 stop6h 25m
Southwest
Deal found 4/29![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:56 am
TYS
- JAN
1 stop3h 19m
Delta
Fri 6/127:00 pm
JAN
- TYS
1 stop3h 54m
Delta
Deal found 4/29![Delta logo]()
$308
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:26 am
TYS
- BTR
1 stop3h 21m
Delta
Mon 6/227:08 pm
BTR
- TYS
1 stop3h 46m
Delta
Deal found 4/30![Delta logo]()
$323
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:59 pm
TYS
- JAN
1 stop6h 19m
Delta
Fri 6/57:23 pm
JAN
- TYS
1 stop3h 33m
Delta
Deal found 4/30![Delta logo]()
$337
Best flights from Knoxville to MississippiDiscover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
Discover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:20 pm
TYS
- MEM
1 stop11h 03m
Allegiant Air
Mon 6/85:04 pm
MEM
- TYS
1 stop22h 08m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$278
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:25 am
TYS
- JAN
1 stop4h 50m
Delta
Fri 6/125:30 am
JAN
- TYS
1 stop3h 08m
Delta
Deal found 5/3![Delta logo]()
$308
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:45 pm
TYS
- MEM
1 stop5h 15m
Southwest
Sat 5/302:45 pm
MEM
- TYS
1 stop2h 45m
Southwest
Deal found 5/1![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:15 am
TYS
- JAN
1 stop4h 58m
United Airlines
Wed 8/192:06 pm
JAN
- TYS
1 stop6h 24m
United Airlines
Deal found 5/3![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:10 pm
TYS
- GPT
1 stop6h 46m
American Airlines
Tue 7/217:04 am
GPT
- TYS
1 stop4h 30m
American Airlines
Deal found 5/3![American Airlines logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:30 am
TYS
- GPT
2 stops13h 40m
Multiple Airlines
Thu 5/217:50 pm
GPT
- TYS
1 stop26h 47m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:33 pm
TYS
- MEM
1 stop4h 39m
Delta
Wed 5/274:11 pm
MEM
- TYS
1 stop3h 21m
Delta
Deal found 4/29![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:45 pm
TYS
- MEM
1 stop5h 10m
Southwest
Mon 6/82:30 pm
MEM
- TYS
2 stops5h 40m
Southwest
Deal found 5/3![Southwest logo]()
$328
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:26 am
TYS
- BTR
1 stop3h 21m
Delta
Mon 6/227:08 pm
BTR
- TYS
1 stop3h 46m
Delta
Deal found 4/30![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:05 pm
TYS
- MEM
2 stops7h 25m
Southwest
Mon 9/149:35 am
MEM
- TYS
1 stop6h 35m
Southwest
Deal found 4/30![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:40 am
TYS
- GPT
1 stop4h 41m
Delta
Tue 7/76:00 pm
GPT
- TYS
1 stop4h 52m
Delta
Deal found 4/29![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:05 pm
TYS
- MEM
2 stops7h 25m
Southwest
Mon 9/289:35 am
MEM
- TYS
1 stop6h 35m
Southwest
Deal found 5/1![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:40 am
TYS
- MOB
1 stop3h 51m
Delta
Sun 7/196:55 pm
MOB
- TYS
1 stop3h 57m
Delta
Deal found 5/1![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:35 am
TYS
- MEM
2 stops9h 55m
Southwest
Fri 6/52:30 pm
MEM
- TYS
2 stops5h 40m
Southwest
Deal found 4/29![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:40 am
TYS
- MOB
1 stop3h 55m
Delta
Mon 6/1512:44 pm
MOB
- TYS
1 stop5h 01m
Delta
Deal found 5/3![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:40 am
TYS
- AEX
2 stops11h 57m
American Airlines
Wed 5/206:00 am
AEX
- TYS
1 stop5h 30m
American Airlines
Deal found 5/1![American Airlines logo]()
$562
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:35 am
TYS
- MEM
2 stops10h 15m
Southwest
Mon 6/112:30 pm
MEM
- TYS
2 stops6h 50m
Southwest
Deal found 5/2![Southwest logo]()
$393
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:59 pm
TYS
- MEM
1 stop3h 24m
Delta
Mon 5/2512:44 pm
MEM
- TYS
1 stop4h 58m
Delta
Deal found 5/2![Delta logo]()
$376
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:25 pm
TYS
- AEX
1 stop24h 25m
United Airlines
Tue 5/264:00 pm
AEX
- TYS
1 stop6h 12m
United Airlines
Deal found 5/2![United Airlines logo]()
$632
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:40 am
TYS
- GPT
1 stop4h 41m
Delta
Wed 6/31:55 pm
GPT
- TYS
1 stop5h 37m
Delta
Deal found 4/29![Delta logo]()
$397
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:45 am
TYS
- MOB
1 stop15h 32m
United Airlines
Sat 8/225:10 pm
MOB
- TYS
1 stop17h 07m
United Airlines
Deal found 5/3![United Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:22 pm
TYS
- BTR
2 stops7h 33m
American Airlines
Wed 8/126:00 am
BTR
- TYS
1 stop5h 56m
American Airlines
Deal found 4/29![American Airlines logo]()
$649
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:15 am
TYS
- MOB
1 stop15h 14m
United Airlines
Tue 8/1812:58 pm
MOB
- TYS
1 stop24h 39m
United Airlines
Deal found 4/30![United Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:57 pm
TYS
- MOB
1 stop5h 58m
Delta
Mon 9/79:10 am
MOB
- TYS
1 stop4h 57m
Delta
Deal found 5/3![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:15 pm
TYS
- JAN
2 stops9h 45m
Southwest
Tue 5/191:00 pm
JAN
- TYS
1 stop5h 40m
Southwest
Deal found 4/29![Southwest logo]()
$492
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:45 am
TYS
- MOB
1 stop15h 40m
United Airlines
Thu 6/1112:50 pm
MOB
- TYS
1 stop10h 04m
United Airlines
Deal found 4/29![United Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
TYS
- JAN
1 stop4h 14m
Delta
Wed 5/205:00 pm
JAN
- TYS
1 stop5h 56m
Delta
Deal found 5/1![Delta logo]()
$437
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:59 pm
TYS
- GPT
1 stop5h 02m
American Airlines
Tue 5/2610:39 am
GPT
- TYS
2 stops10h 20m
American Airlines
Deal found 4/30![American Airlines logo]()
$811
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:40 am
TYS
- JAN
1 stop5h 24m
Delta
Mon 5/187:23 pm
JAN
- TYS
1 stop3h 33m
Delta
Deal found 5/1![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:45 pm
TYS
- GPT
2 stops20h 40m
United Airlines
Fri 7/105:19 pm
GPT
- TYS
2 stops28h 15m
United Airlines
Deal found 5/2![United Airlines logo]()
$722
Last-minute flights from Knoxville to MississippiDiscover last-minute flight deals from Knoxville to Mississippi. Data last updated May 4, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mississippi. Data last updated May 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
- MEM
1 stop21h 09m
Allegiant Air
Mon 5/188:05 am
MEM
- TYS
1 stop13h 19m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 am
TYS
- MEM
1 stop11h 19m
Allegiant Air
Mon 5/188:05 am
MEM
- TYS
1 stop13h 19m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
TYS
- MEM
2 stops11h 23m
Multiple Airlines
Mon 5/188:05 am
MEM
- TYS
1 stop13h 19m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 am
TYS
- MEM
1 stop11h 19m
Multiple Airlines
Sun 5/175:37 pm
MEM
- TYS
1 stop22h 53m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:33 pm
TYS
- MEM
1 stop4h 39m
Delta
Wed 5/274:11 pm
MEM
- TYS
1 stop3h 21m
Delta
Deal found 4/29![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
TYS
- MEM
1 stop4h 55m
Southwest
Wed 6/39:45 am
MEM
- TYS
1 stop6h 25m
Southwest
Deal found 4/29![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:35 am
TYS
- MOB
1 stop4h 30m
Delta
Thu 6/44:44 pm
MOB
- TYS
1 stop6h 12m
Delta
Deal found 4/30![Delta logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:03 pm
TYS
- MEM
1 stop19h 29m
Multiple Airlines
Fri 6/55:04 pm
MEM
- TYS
1 stop14h 31m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:55 pm
TYS
- MEM
2 stops23h 39m
Multiple Airlines
Mon 6/15:04 pm
MEM
- TYS
1 stop22h 11m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:36 pm
TYS
- MEM
1 stop22h 58m
Allegiant Air
Mon 6/15:04 pm
MEM
- TYS
1 stop22h 11m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$289
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:59 pm
TYS
- JAN
1 stop6h 19m
Delta
Fri 6/57:23 pm
JAN
- TYS
1 stop3h 33m
Delta
Deal found 4/30![Delta logo]()
$337
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:07 pm
TYS
- GPT
1 stop6h 54m
American Airlines
Mon 6/16:38 pm
GPT
- TYS
1 stop4h 09m
American Airlines
Deal found 5/2![American Airlines logo]()
$362
One-way flights from Knoxville to MississippiSearch for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
Search for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
- MEM
1 stop21h 09m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:25 pm
TYS
- MEM
1 stop26h 30m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:24 pm
TYS
- MEM
1 stop22h 08m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$135
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:27 am
TYS
- JAN
1 stop3h 37m
Delta
Deal found 4/29![Delta logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:15 am
TYS
- MEM
1 stop12h 28m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$141
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:40 am
TYS
- JAN
1 stop4h 14m
Delta
Deal found 5/3![Delta logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:56 pm
TYS
- GPT
2 stops43h 45m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
- MEM
2 stops21h 43m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/283:54 pm
TYS
- MEM
1 stop5h 41m
Delta
Deal found 5/3![Delta logo]()
$178
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:45 pm
TYS
- MEM
2 stops11h 00m
Southwest
Deal found 5/3![Southwest logo]()
$183
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:40 am
TYS
- MOB
1 stop3h 58m
Delta
Deal found 4/29![Delta logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:55 pm
TYS
- MEM
2 stops47h 04m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$196
Find flight deals from Knoxville to Mississippi
Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated May 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $202 (Kiwi.com) |
One-way from | $113 (Kiwi.com) |
Popular in | September |
Cheapest in | June |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Thu 6/4
9:20 pm-7:23 am
1 stop11h 03m
Memphis
Mon 6/8
5:04 pm-4:12 pm
1 stop22h 08m
$278
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Tue 6/2
10:25 am-2:15 pm
1 stop4h 50m
Jackson-Evers Intl
Fri 6/12
5:30 am-9:38 am
1 stop3h 08m
$308
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Tue 5/26
7:33 pm-11:12 pm
1 stop4h 39m
Memphis
Wed 5/27
4:11 pm-8:32 pm
1 stop3h 21m
$311
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Mon 5/25
6:45 pm-11:00 pm
1 stop5h 15m
Memphis
Sat 5/30
2:45 pm-6:30 pm
1 stop2h 45m
$323
Quickest round-trip
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
Thu 6/18
10:26 am-12:47 pm
1 stop3h 21m
Baton Rouge Ryan
Mon 6/22
7:08 pm-11:54 pm
1 stop3h 46m
$323
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Thu 6/4
7:45 pm-11:55 pm
1 stop5h 10m
Memphis
Mon 6/8
2:30 pm-9:10 pm
2 stops5h 40m
$328
KnoxvilleGulfport
TYS - GPT
TYSGPT
Knoxville McGhee Tyson
Tue 6/30
5:40 am-9:21 am
1 stop4h 41m
Gulfport Biloxi Regional
Tue 7/7
6:00 pm-11:52 pm
1 stop4h 52m
$347
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Tue 8/18
7:15 am-11:13 am
1 stop4h 58m
Jackson-Evers Intl
Wed 8/19
2:06 pm-9:30 pm
1 stop6h 24m
$349
KnoxvilleMobile
TYS - MOB
TYSMOB
Knoxville McGhee Tyson
Wed 7/15
5:40 am-8:31 am
1 stop3h 51m
Mobile
Sun 7/19
6:55 pm-11:52 pm
1 stop3h 57m
$357
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Fri 9/11
2:05 pm-8:30 pm
2 stops7h 25m
Memphis
Mon 9/14
9:35 am-5:10 pm
1 stop6h 35m
$362
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
TYS-MEM
TYS-JAN
TYS-BTR
TYS-GPT
TYS-MOB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mississippi
TYS-USMS
TYS-MEM
TYS-JAN
TYS-BTR
TYS-GPT
What is the cheapest month to book a flight from Knoxville to Mississippi?
Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated May 4, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Mississippi
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Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Knoxville to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Mississippi flights
Browse other Knoxville and Mississippi flight options. Last updated on May 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Mississippi flights
Consider these flights traveling from Knoxville to Mississippi.
Top 2 airlines flying from Knoxville to Mississippi
Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$209 | Average$442 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$233 | Average$366 | FlexibilityNo cancel fee | On-time71% |