Mississippi

$113+ Cheap flights from Knoxville (TYS) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Jun 3 — Jun 101
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Cheap flight deals from Knoxville to Mississippi

Cheapest flights from Knoxville to Mississippi
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:40 pm
TYS
-
MEM
1 stop21h 09m
Allegiant Air
Mon 5/188:05 am
MEM
-
TYS
1 stop13h 19m
Allegiant Air
Deal found 4/29$202
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:03 pm
TYS
-
MEM
1 stop19h 29m
Multiple Airlines
Fri 6/55:04 pm
MEM
-
TYS
1 stop14h 31m
Multiple Airlines
Deal found 5/1$230
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:55 pm
TYS
-
MEM
2 stops23h 39m
Multiple Airlines
Mon 6/15:04 pm
MEM
-
TYS
1 stop22h 11m
Multiple Airlines
Deal found 5/2$243
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:06 pm
TYS
-
MEM
1 stop18h 43m
Allegiant Air
Mon 7/204:49 pm
MEM
-
TYS
1 stop22h 21m
Allegiant Air
Deal found 5/3$255
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 am
TYS
-
MEM
1 stop11h 19m
Allegiant Air
Mon 5/188:05 am
MEM
-
TYS
1 stop13h 19m
Allegiant Air
Deal found 5/3$270
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:05 pm
TYS
-
MEM
1 stop18h 41m
Allegiant Air
Mon 6/85:04 pm
MEM
-
TYS
1 stop22h 08m
Allegiant Air
Deal found 5/1$272
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
TYS
-
MEM
2 stops11h 23m
Multiple Airlines
Mon 5/188:05 am
MEM
-
TYS
1 stop13h 19m
Multiple Airlines
Deal found 5/3$287
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:36 pm
TYS
-
MEM
1 stop22h 58m
Allegiant Air
Mon 6/15:04 pm
MEM
-
TYS
1 stop22h 11m
Allegiant Air
Deal found 5/2$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
TYS
-
MEM
1 stop4h 55m
Southwest
Wed 6/39:45 am
MEM
-
TYS
1 stop6h 25m
Southwest
Deal found 4/29$295
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:56 am
TYS
-
JAN
1 stop3h 19m
Delta
Fri 6/127:00 pm
JAN
-
TYS
1 stop3h 54m
Delta
Deal found 4/29$308
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:26 am
TYS
-
BTR
1 stop3h 21m
Delta
Mon 6/227:08 pm
BTR
-
TYS
1 stop3h 46m
Delta
Deal found 4/30$323
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:59 pm
TYS
-
JAN
1 stop6h 19m
Delta
Fri 6/57:23 pm
JAN
-
TYS
1 stop3h 33m
Delta
Deal found 4/30$337

Find flight deals from Knoxville to Mississippi

Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated May 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$202
(Kiwi.com)

One-way from

$113
(Kiwi.com)

Popular in

September

Cheapest in

June
Provider with most accurate pricing for Knoxville McGhee Tyson-Jackson-Evers Intl flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Jackson-Evers Intl flights.
From Knoxville McGhee Tyson to Mississippi
One-way flight from Knoxville McGhee Tyson to Mississippi
Highest demand for flights based on searches. 9% potential increase in price ($46 potential increase over avg. RT price).
Cheapest flight prices on average. 9% potential price decrease ($37 potential savings vs. average RT price).

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Thu 6/4

9:20 pm-7:23 am

1 stop11h 03m

Memphis

Mon 6/8

5:04 pm-4:12 pm

1 stop22h 08m

$278

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Tue 6/2

10:25 am-2:15 pm

1 stop4h 50m

Jackson-Evers Intl

Fri 6/12

5:30 am-9:38 am

1 stop3h 08m

$308

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Tue 5/26

7:33 pm-11:12 pm

1 stop4h 39m

Memphis

Wed 5/27

4:11 pm-8:32 pm

1 stop3h 21m

$311

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Mon 5/25

6:45 pm-11:00 pm

1 stop5h 15m

Memphis

Sat 5/30

2:45 pm-6:30 pm

1 stop2h 45m

$323
Quickest round-trip

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Thu 6/18

10:26 am-12:47 pm

1 stop3h 21m

Baton Rouge Ryan

Mon 6/22

7:08 pm-11:54 pm

1 stop3h 46m

$323

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Thu 6/4

7:45 pm-11:55 pm

1 stop5h 10m

Memphis

Mon 6/8

2:30 pm-9:10 pm

2 stops5h 40m

$328

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

Tue 6/30

5:40 am-9:21 am

1 stop4h 41m

Gulfport Biloxi Regional

Tue 7/7

6:00 pm-11:52 pm

1 stop4h 52m

$347

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Tue 8/18

7:15 am-11:13 am

1 stop4h 58m

Jackson-Evers Intl

Wed 8/19

2:06 pm-9:30 pm

1 stop6h 24m

$349

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 7/15

5:40 am-8:31 am

1 stop3h 51m

Mobile

Sun 7/19

6:55 pm-11:52 pm

1 stop3h 57m

$357

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Fri 9/11

2:05 pm-8:30 pm

2 stops7h 25m

Memphis

Mon 9/14

9:35 am-5:10 pm

1 stop6h 35m

$362

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mississippi

What is the cheapest month to book a flight from Knoxville to Mississippi?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated May 4, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Mississippi?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Mississippi. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Mississippi?

    For as low as $308, Allegiant Air can have you in Mississippi from Knoxville in 4h 50m. The distance between Knoxville and Mississippi is about 424 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Mississippi?

  • Can I find deals for flights from Knoxville to Mississippi that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mississippi.

  • Can I find deals for business class flights from Knoxville to Mississippi?

    Yes. Cheapflights offers flight deals from Knoxville to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mississippi?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Knoxville to Mississippi

Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$209Average$442FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$233Average$366FlexibilityNo cancel feeOn-time71%

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