$47+ Cheap flights from Knoxville (TYS) to Mississippi
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Aug 29 — Sep 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Mississippi
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MississippiExplore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Booking.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:45 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Sun 10/183:21 pm
MEM
- TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/26![Allegiant Air logo]()
$84
This Expedia deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:47 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Sun 11/86:46 pm
MEM
- TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/29![Allegiant Air logo]()
$90
This Booking.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:48 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Sun 9/276:47 pm
MEM
- TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/27![Allegiant Air logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:35 am
TYS
- MEM
1 stop11h 43m
Multiple Airlines
Sun 11/86:46 pm
MEM
- TYS
Nonstop1h 12m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:47 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Mon 11/98:55 am
MEM
- TYS
1 stop26h 40m
Allegiant Air
Deal found 7/29![Allegiant Air logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:17 pm
TYS
- MEM
2 stops27h 01m
Multiple Airlines
Sun 9/276:47 pm
MEM
- TYS
Nonstop1h 12m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:11 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Thu 10/81:55 pm
MEM
- TYS
1 stop16h 48m
Allegiant Air
Deal found 7/27![Allegiant Air logo]()
$207
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:06 pm
TYS
- JAN
1 stop5h 46m
American Airlines
Sat 9/193:27 pm
JAN
- TYS
1 stop4h 39m
American Airlines
Deal found 7/29![American Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:40 am
TYS
- JAN
1 stop5h 57m
Delta
Sat 8/298:00 am
JAN
- TYS
1 stop3h 28m
Delta
Deal found 7/27![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:05 am
TYS
- JAN
2 stops11h 00m
Southwest
Tue 9/11:30 pm
JAN
- TYS
1 stop4h 25m
Southwest
Deal found 7/28![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:50 am
TYS
- JAN
1 stop8h 05m
Southwest
Sat 9/196:00 am
JAN
- TYS
2 stops6h 15m
Southwest
Deal found 7/29![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:55 pm
TYS
- JAN
2 stops6h 50m
Southwest
Wed 9/21:30 pm
JAN
- TYS
1 stop4h 25m
Southwest
Deal found 7/28![Southwest logo]()
$291
Best flights from Knoxville to MississippiDiscover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:35 am
TYS
- JAN
1 stop4h 37m
Delta
Tue 9/15:01 pm
JAN
- TYS
1 stop5h 51m
Delta
Deal found 7/28![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:02 pm
TYS
- MEM
1 stop6h 16m
United Airlines
Sat 8/292:37 pm
MEM
- TYS
1 stop5h 16m
United Airlines
Deal found 7/25![United Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:25 pm
TYS
- MEM
1 stop4h 25m
American Airlines
Mon 8/318:15 am
MEM
- TYS
1 stop6h 42m
American Airlines
Deal found 7/27![American Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:45 pm
TYS
- MEM
1 stop5h 15m
Southwest
Tue 9/88:15 am
MEM
- TYS
1 stop2h 50m
Southwest
Deal found 7/28![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:45 pm
TYS
- MEM
1 stop5h 15m
Southwest
Sat 9/199:20 am
MEM
- TYS
2 stops7h 25m
Southwest
Deal found 7/25![Southwest logo]()
$280
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:30 am
TYS
- JAN
1 stop4h 07m
Delta
Thu 8/205:01 pm
JAN
- TYS
1 stop3h 59m
Delta
Deal found 7/29![Delta logo]()
$298
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:55 pm
TYS
- MEM
1 stop3h 10m
Southwest
Sat 8/299:20 am
MEM
- TYS
2 stops9h 00m
Southwest
Deal found 7/25![Southwest logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 pm
TYS
- JAN
1 stop5h 34m
American Airlines
Sun 8/307:25 am
JAN
- TYS
1 stop6h 48m
American Airlines
Deal found 7/29![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am
TYS
- MEM
1 stop3h 07m
Delta
Sat 9/196:10 pm
MEM
- TYS
1 stop3h 17m
Delta
Deal found 7/25![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:40 pm
TYS
- AEX
1 stop5h 20m
United Airlines
Sun 8/164:08 pm
AEX
- TYS
1 stop4h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:55 pm
TYS
- JAN
2 stops6h 50m
Southwest
Thu 8/205:55 am
JAN
- TYS
2 stops6h 30m
Southwest
Deal found 7/29![Southwest logo]()
$296
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:05 pm
TYS
- GPT
1 stop5h 25m
American Airlines
Sat 8/291:50 pm
GPT
- TYS
1 stop4h 10m
American Airlines
Deal found 7/27![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:12 pm
TYS
- GPT
1 stop5h 09m
Delta
Sun 8/236:00 pm
GPT
- TYS
1 stop4h 52m
Delta
Deal found 7/26![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:15 am
TYS
- JAN
1 stop7h 21m
American Airlines
Sun 8/307:25 am
JAN
- TYS
1 stop6h 48m
American Airlines
Deal found 7/25![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:15 am
TYS
- BTR
1 stop4h 58m
United Airlines
Sat 8/2912:00 pm
BTR
- TYS
1 stop5h 17m
United Airlines
Deal found 7/25![United Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:45 pm
TYS
- MEM
2 stops10h 00m
Southwest
Fri 8/215:45 am
MEM
- TYS
2 stops5h 35m
Southwest
Deal found 7/27![Southwest logo]()
$317
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:41 pm
TYS
- JAN
1 stop4h 30m
Delta
Sun 8/301:00 pm
JAN
- TYS
1 stop6h 10m
Delta
Deal found 7/28![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:55 pm
TYS
- MEM
2 stops6h 55m
Southwest
Fri 8/219:35 am
MEM
- TYS
2 stops8h 00m
Southwest
Deal found 7/27![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:00 am
TYS
- BTR
1 stop5h 04m
United Airlines
Sat 1/95:00 am
BTR
- TYS
1 stop7h 20m
United Airlines
Deal found 7/27![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:12 pm
TYS
- BTR
1 stop4h 49m
Delta
Sun 8/2310:26 am
BTR
- TYS
1 stop4h 04m
Delta
Deal found 7/27![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:45 pm
TYS
- MEM
1 stop5h 15m
Southwest
Mon 9/711:20 am
MEM
- TYS
1 stop7h 40m
Southwest
Deal found 7/25![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:50 pm
TYS
- AEX
1 stop5h 09m
American Airlines
Sun 8/165:00 am
AEX
- TYS
2 stops11h 35m
American Airlines
Deal found 7/28![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:15 am
TYS
- GPT
1 stop7h 09m
United Airlines
Mon 8/312:00 pm
GPT
- TYS
1 stop6h 45m
United Airlines
Deal found 7/29![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:41 pm
TYS
- GPT
1 stop3h 40m
Delta
Thu 8/206:30 am
GPT
- TYS
1 stop3h 41m
Delta
Deal found 7/27![Delta logo]()
$350
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:25 am
TYS
- JAN
2 stops12h 45m
Southwest
Wed 9/27:05 am
JAN
- TYS
2 stops11h 45m
Southwest
Deal found 7/28![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/229:15 am
TYS
- GPT
1 stop7h 47m
United Airlines
Mon 1/251:54 pm
GPT
- TYS
1 stop4h 40m
United Airlines
Deal found 7/25![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:06 pm
TYS
- MOB
1 stop4h 48m
American Airlines
Sat 10/317:15 am
MOB
- TYS
1 stop4h 13m
American Airlines
Deal found 7/28![American Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:38 pm
TYS
- MOB
1 stop4h 02m
Delta
Sun 10/116:00 am
MOB
- TYS
1 stop3h 54m
Delta
Deal found 7/27![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:05 pm
TYS
- JAN
2 stops7h 05m
Southwest
Mon 8/3112:40 pm
JAN
- TYS
1 stop4h 55m
Southwest
Deal found 7/27![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:23 pm
TYS
- MOB
1 stop5h 49m
Delta
Tue 10/136:00 am
MOB
- TYS
1 stop3h 54m
Delta
Deal found 7/25![Delta logo]()
$367
Last-minute flights from Knoxville to MississippiDiscover last-minute flight deals from Knoxville to Mississippi. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mississippi. Data last updated July 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:55 pm
TYS
- JAN
2 stops6h 50m
Southwest
Thu 8/205:55 am
JAN
- TYS
2 stops6h 30m
Southwest
Deal found 7/29![Southwest logo]()
$296
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:30 am
TYS
- JAN
1 stop4h 07m
Delta
Thu 8/205:01 pm
JAN
- TYS
1 stop3h 59m
Delta
Deal found 7/29![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:15 am
TYS
- MEM
1 stop5h 18m
American Airlines
Fri 8/218:15 am
MEM
- TYS
1 stop4h 16m
American Airlines
Deal found 7/27![American Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:52 pm
TYS
- MEM
2 stops26h 31m
Multiple Airlines
Mon 8/247:03 pm
MEM
- TYS
1 stop13h 37m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:05 pm
TYS
- MEM
2 stops7h 25m
Southwest
Mon 8/249:35 am
MEM
- TYS
2 stops8h 00m
Southwest
Deal found 7/26![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:02 pm
TYS
- MEM
1 stop6h 16m
United Airlines
Sat 8/292:37 pm
MEM
- TYS
1 stop5h 16m
United Airlines
Deal found 7/25![United Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:55 pm
TYS
- MEM
1 stop3h 10m
Southwest
Sat 8/299:20 am
MEM
- TYS
2 stops9h 00m
Southwest
Deal found 7/25![Southwest logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/234:52 pm
TYS
- MEM
2 stops26h 31m
Multiple Airlines
Sun 8/303:57 pm
MEM
- TYS
1 stop25h 07m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:05 am
TYS
- JAN
2 stops11h 00m
Southwest
Tue 9/11:30 pm
JAN
- TYS
1 stop4h 25m
Southwest
Deal found 7/28![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:45 pm
TYS
- MEM
2 stops10h 00m
Southwest
Thu 8/275:45 am
MEM
- TYS
2 stops6h 40m
Southwest
Deal found 7/25![Southwest logo]()
$285
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:21 pm
TYS
- JAN
1 stop6h 44m
United Airlines
Sat 8/292:05 pm
JAN
- TYS
1 stop6h 40m
United Airlines
Deal found 7/27![United Airlines logo]()
$273
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:15 am
TYS
- GPT
1 stop7h 09m
United Airlines
Sat 8/292:00 pm
GPT
- TYS
1 stop6h 45m
United Airlines
Deal found 7/27![United Airlines logo]()
$299
One-way flights from Knoxville to MississippiSearch for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:48 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$47
This Gotogate deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:38 pm
TYS
- MEM
Nonstop1h 19m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:28 am
TYS
- MEM
1 stop6h 02m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:54 am
TYS
- MEM
1 stop29h 15m
Allegiant Air
Deal found 7/27![Allegiant Air logo]()
$133
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:45 pm
TYS
- MEM
1 stop5h 15m
Southwest
Deal found 7/29![Southwest logo]()
$138
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
TYS
- MEM
2 stops7h 40m
Southwest
Deal found 7/27![Southwest logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:29 pm
TYS
- MEM
1 stop20h 45m
Allegiant Air
Deal found 7/29![Allegiant Air logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/234:52 pm
TYS
- MEM
2 stops26h 31m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:49 pm
TYS
- GPT
2 stops40h 52m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$151
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:50 pm
TYS
- MEM
1 stop9h 55m
Southwest
Deal found 7/28![Southwest logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:26 am
TYS
- MEM
1 stop23h 48m
Allegiant Air
Deal found 7/29![Allegiant Air logo]()
$163
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:10 am
TYS
- MEM
1 stop2h 50m
Southwest
Deal found 7/28![Southwest logo]()
$170
Find flight deals from Knoxville to Mississippi
Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated July 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $84 (Booking.com) |
One-way from | $47 (Kiwi.com) |
Popular in | September |
Cheapest in | January |
Average price | $477 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Tue 9/1
8:35 am-12:12 pm
1 stop4h 37m
Jackson-Evers Intl
Tue 9/1
5:01 pm-11:52 pm
1 stop5h 51m
$273
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Sat 8/22
6:02 pm-11:18 pm
1 stop6h 16m
Memphis
Sat 8/29
2:37 pm-8:53 pm
1 stop5h 16m
$275
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Mon 8/24
7:25 pm-10:50 pm
1 stop4h 25m
Memphis
Mon 8/31
8:15 am-3:57 pm
1 stop6h 42m
$275
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Thu 9/3
5:45 pm-10:00 pm
1 stop5h 15m
Memphis
Tue 9/8
8:15 am-12:05 pm
1 stop2h 50m
$275
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Thu 9/17
5:45 pm-10:00 pm
1 stop5h 15m
Memphis
Sat 9/19
9:20 am-5:45 pm
2 stops7h 25m
$280
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Sat 8/22
4:55 pm-7:05 pm
1 stop3h 10m
Memphis
Sat 8/29
9:20 am-7:20 pm
2 stops9h 00m
$280
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Tue 8/18
1:55 pm-7:45 pm
2 stops6h 50m
Jackson-Evers Intl
Thu 8/20
5:55 am-1:25 pm
2 stops6h 30m
$296
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Tue 8/18
7:30 am-10:37 am
1 stop4h 07m
Jackson-Evers Intl
Thu 8/20
5:01 pm-10:00 pm
1 stop3h 59m
$298
Quickest round-trip
KnoxvilleMemphis
TYS - MEM
TYSMEM
Knoxville McGhee Tyson
Thu 9/17
5:40 am-7:47 am
1 stop3h 07m
Memphis
Sat 9/19
6:10 pm-10:27 pm
1 stop3h 17m
$305
KnoxvilleJackson
TYS - JAN
TYSJAN
Knoxville McGhee Tyson
Thu 8/27
6:05 pm-10:39 pm
1 stop5h 34m
Jackson-Evers Intl
Sun 8/30
7:25 am-3:13 pm
1 stop6h 48m
$310
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
TYS-MEM
TYS-JAN
TYS-GPT
TYS-BTR
TYS-MOB
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mississippi
TYS-USMS
TYS-MEM
TYS-JAN
TYS-GPT
TYS-BTR
What is the cheapest month to book a flight from Knoxville to Mississippi?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $319). Flying from Knoxville to Mississippi in September is currently the most expensive (average of $813). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 30, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Entertainment
7.8
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Knoxville to Mississippi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mississippi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Mississippi by cabin class
Find flights from Knoxville to Mississippi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Mississippi flights
Browse other Knoxville and Mississippi flight options. Last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Mississippi flights
Consider these flights traveling from Knoxville to Mississippi.
Top 2 airlines flying from Knoxville to Mississippi
Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$454 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$416 | FlexibilityNo cancel fee | On-time71% |