$160+ Cheap flights from Knoxville (TYS) to Mississippi
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Oct 29 — Nov 51
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mississippi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to MississippiExplore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:14 pm -
2 stops41h 37m
Sun 10/257:45 pm -
1 stop14h 29m
Deal found 9/24![Multiple Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:45 am -
2 stops9h 00m
Sun 11/2211:45 am -
1 stop7h 50m
Deal found 9/24![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:04 pm -
1 stop4h 57m
Sat 11/215:49 pm -
1 stop5h 10m
Deal found 9/26![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 am -
1 stop7h 10m
Sat 10/242:00 pm -
1 stop6h 55m
Deal found 9/26![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop4h 37m
Mon 11/96:04 pm -
1 stop4h 55m
Deal found 9/25![Delta logo]()
$397
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:29 am -
1 stop3h 32m
Sun 10/256:26 am -
1 stop6h 14m
Deal found 9/24![Delta logo]()
$400
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:12 pm -
1 stop7h 29m
Tue 11/31:48 pm -
1 stop3h 56m
Deal found 9/28![American Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:33 pm -
1 stop21h 33m
Mon 11/96:46 pm -
2 stops21h 32m
Deal found 9/25![Multiple Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
2 stops14h 05m
Sun 11/17:45 pm -
1 stop14h 29m
Deal found 9/27![Multiple Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:05 pm -
1 stop5h 04m
Sun 11/226:30 pm -
1 stop4h 29m
Deal found 9/24![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:06 pm -
1 stop6h 14m
Sun 11/16:26 am -
1 stop6h 05m
Deal found 9/27![Delta logo]()
$468
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:13 pm -
1 stop5h 36m
Sat 10/176:42 pm -
1 stop4h 13m
Deal found 9/28![American Airlines logo]()
$477
Best flights from Knoxville to MississippiDiscover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Knoxville to Mississippi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/712:00 pm -
1 stop5h 02m
Tue 1/121:54 pm -
1 stop7h 20m
Deal found 9/26![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:45 am -
2 stops9h 00m
Sun 11/2211:45 am -
1 stop7h 50m
Deal found 9/24![Southwest logo]()
$388
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop4h 37m
Sun 11/86:26 am -
1 stop3h 28m
Deal found 9/24![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:12 pm -
1 stop7h 29m
Tue 11/31:48 pm -
1 stop3h 56m
Deal found 9/28![American Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:20 pm -
1 stop4h 58m
Wed 2/31:57 pm -
1 stop7h 17m
Deal found 9/27![United Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:23 pm -
1 stop4h 53m
Sun 11/16:26 am -
1 stop6h 05m
Deal found 9/27![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:05 pm -
1 stop5h 04m
Sun 11/226:30 pm -
1 stop4h 29m
Deal found 9/24![American Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/267:00 am -
1 stop7h 26m
Sat 1/301:54 pm -
1 stop7h 20m
Deal found 9/27![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:06 pm -
1 stop6h 14m
Sun 11/16:26 am -
1 stop6h 05m
Deal found 9/27![Delta logo]()
$468
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:15 am -
2 stops13h 30m
Thu 10/1512:00 pm -
2 stops8h 35m
Deal found 9/26![Southwest logo]()
$623
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:50 pm -
2 stops9h 05m
Fri 10/165:55 am -
2 stops14h 40m
Deal found 9/27![Southwest logo]()
$659
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/295:38 pm -
2 stops23h 24m
Mon 2/11:54 pm -
1 stop7h 20m
Deal found 9/27![United Airlines logo]()
$656
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/912:00 pm -
1 stop4h 53m
Wed 2/105:20 pm -
2 stops20h 16m
Deal found 9/24![United Airlines logo]()
$737
Last-minute flights from Knoxville to MississippiDiscover last-minute flight deals from Knoxville to Mississippi. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mississippi. Data last updated September 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:09 pm -
1 stop6h 03m
Sun 10/47:00 am -
1 stop7h 16m
Deal found 9/28![American Airlines logo]()
$565
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:14 pm -
2 stops41h 37m
Sun 10/117:45 pm -
1 stop14h 29m
Deal found 9/25![Multiple Airlines logo]()
$533
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:20 am -
2 stops10h 40m
Sat 10/1011:25 am -
1 stop5h 30m
Deal found 9/24![Southwest logo]()
$608
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:15 am -
2 stops13h 30m
Thu 10/1512:00 pm -
1 stop9h 45m
Deal found 9/26![Southwest logo]()
$619
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:06 pm -
1 stop5h 11m
Fri 10/167:29 pm -
1 stop3h 30m
Deal found 9/27![Delta logo]()
$503
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:13 pm -
1 stop5h 36m
Sat 10/176:42 pm -
1 stop4h 13m
Deal found 9/28![American Airlines logo]()
$477
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:14 pm -
2 stops41h 37m
Sun 10/257:45 pm -
1 stop14h 29m
Deal found 9/24![Multiple Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 am -
1 stop7h 10m
Sat 10/242:00 pm -
1 stop6h 55m
Deal found 9/26![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:29 am -
1 stop3h 32m
Sun 10/256:26 am -
1 stop6h 14m
Deal found 9/24![Delta logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
2 stops14h 05m
Sun 11/17:45 pm -
1 stop14h 29m
Deal found 9/27![Multiple Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:06 pm -
1 stop6h 14m
Sun 11/16:26 am -
1 stop6h 05m
Deal found 9/27![Delta logo]()
$468
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:23 pm -
1 stop4h 53m
Sun 11/16:26 am -
1 stop6h 05m
Deal found 9/27![Delta logo]()
$397
One-way flights from Knoxville to MississippiSearch for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from Knoxville to Mississippi. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:14 pm -
2 stops41h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$160
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
1 stop4h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:37 pm -
2 stops16h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$201
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:04 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$202
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:40 am -
1 stop4h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:17 pm -
3 stops54h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:04 pm -
3 stops52h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$234
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:13 pm -
1 stop5h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:18 pm -
1 stop4h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:10 am -
2 stops7h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:00 am -
2 stops29h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$408
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:50 am -
1 stop3h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$480
Find flight deals from Knoxville to Mississippi
Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $310 (Kiwi.com) |
One-way from | $160 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $559 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGulfport
TYS Knoxville McGhee Tyson - GPT Gulfport Biloxi Regional
TYSGPT
Knoxville McGhee Tyson
Wed 10/28
5:40 am-9:17 am
1 stop4h 37m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$200
KnoxvilleGulfport
TYS Knoxville McGhee Tyson - GPT Gulfport Biloxi Regional
TYSGPT
Knoxville McGhee Tyson
Fri 11/13
8:04 pm-11:59 pm
1 stop4h 55m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$213
KnoxvilleGulfport
TYS Knoxville McGhee Tyson - GPT Gulfport Biloxi Regional
TYSGPT
Knoxville McGhee Tyson
Fri 11/13
5:40 am-9:19 am
1 stop4h 39m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$213
KnoxvilleGulfport
TYS Knoxville McGhee Tyson - GPT Gulfport Biloxi Regional
TYSGPT
Knoxville McGhee Tyson
Thu 11/12
1:50 pm-8:51 am
3 stops20h 01m
Gulfport Biloxi Regional
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$289
KnoxvilleJackson
TYS Knoxville McGhee Tyson - JAN Jackson-Evers Intl
TYSJAN
Knoxville McGhee Tyson
Sat 10/3
7:18 pm-10:52 pm
1 stop4h 34m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$299
KnoxvilleGulfport
TYS Knoxville McGhee Tyson - GPT Gulfport Biloxi Regional
TYSGPT
Knoxville McGhee Tyson
Thu 1/7
12:00 pm-4:02 pm
1 stop5h 02m
Gulfport Biloxi Regional
Tue 1/12
1:54 pm-10:14 pm
1 stop7h 20m
$334
KnoxvilleJackson
TYS Knoxville McGhee Tyson - JAN Jackson-Evers Intl
TYSJAN
Knoxville McGhee Tyson
Tue 2/2
5:20 pm-9:18 pm
1 stop4h 58m
Jackson-Evers Intl
Wed 2/3
1:57 pm-10:14 pm
1 stop7h 17m
$363
KnoxvilleJackson
TYS Knoxville McGhee Tyson - JAN Jackson-Evers Intl
TYSJAN
Knoxville McGhee Tyson
Sat 10/3
8:10 am-2:45 pm
2 stops7h 35m
Jackson-Evers Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$369
KnoxvilleJackson
TYS Knoxville McGhee Tyson - JAN Jackson-Evers Intl
TYSJAN
Knoxville McGhee Tyson
Fri 11/20
11:45 am-7:45 pm
2 stops9h 00m
Jackson-Evers Intl
Sun 11/22
11:45 am-8:35 pm
1 stop7h 50m
$388
KnoxvilleGulfport
TYS Knoxville McGhee Tyson - GPT Gulfport Biloxi Regional
TYSGPT
Knoxville McGhee Tyson
Thu 11/5
5:40 am-9:17 am
1 stop4h 37m
Gulfport Biloxi Regional
Sun 11/8
6:26 am-10:54 am
1 stop3h 28m
$397
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mississippi
Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
TYS-GPT
TYS-JAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mississippi
TYS-USMS
TYS-GPT
TYS-JAN
What is the cheapest month to book a flight from Knoxville to Mississippi?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $319). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $734). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mississippi
Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 29, 2026.
Read reviews from past customers who have flown Delta from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Overall
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Mississippi
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Complete your trip
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Knoxville and Mississippi flights
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Knoxville to Mississippi flights
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Top airline flying from Knoxville to Mississippi
Discover the top airline that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$306 | Average$447 | FlexibilityNo cancel fee | On-timeN/A |