Mississippi

$85+ Cheap flights from Knoxville (TYS) to Mississippi

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Aug 2 — Aug 91
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Cheap flight deals from Knoxville to Mississippi

Cheapest flights from Knoxville to Mississippi
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.

This Booking.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:45 pm
TYS
-
MEM
Nonstop1h 19m
Allegiant Air
Sun 10/183:21 pm
MEM
-
TYS
Nonstop1h 12m
Allegiant Air
Deal found 7/1$85
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:48 pm
TYS
-
MEM
Nonstop1h 19m
Multiple Airlines
Mon 9/287:58 pm
MEM
-
TYS
1 stop18h 21m
Multiple Airlines
Deal found 6/29$167
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/262:08 pm
TYS
-
MEM
1 stop18h 41m
Multiple Airlines
Sun 8/27:10 pm
MEM
-
TYS
1 stop27h 23m
Multiple Airlines
Deal found 6/28$226
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:26 am
TYS
-
MEM
1 stop23h 48m
Allegiant Air
Sun 8/168:34 am
MEM
-
TYS
1 stop23h 02m
Allegiant Air
Deal found 6/28$227
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/192:08 pm
TYS
-
MEM
1 stop18h 41m
Allegiant Air
Thu 7/238:40 pm
MEM
-
TYS
1 stop25h 39m
Allegiant Air
Deal found 6/30$232
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:30 am
TYS
-
MEM
1 stop10h 53m
Multiple Airlines
Sun 8/28:22 am
MEM
-
TYS
1 stop13h 41m
Multiple Airlines
Deal found 6/28$247
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:30 am
TYS
-
JAN
1 stop5h 35m
Delta
Sat 12/55:35 pm
JAN
-
TYS
1 stop5h 11m
Delta
Deal found 6/30$301
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 am
TYS
-
JAN
1 stop8h 05m
Southwest
Mon 9/75:55 am
JAN
-
TYS
2 stops6h 30m
Southwest
Deal found 6/28$312
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:37 am
TYS
-
BTR
1 stop6h 21m
American Airlines
Sun 8/26:28 pm
BTR
-
TYS
1 stop4h 23m
American Airlines
Deal found 6/30$329
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:15 am
TYS
-
GPT
2 stops25h 26m
Multiple Airlines
Thu 8/67:25 pm
GPT
-
TYS
1 stop26h 19m
Multiple Airlines
Deal found 6/30$335
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm
TYS
-
JAN
1 stop4h 52m
Delta
Mon 9/75:01 pm
JAN
-
TYS
1 stop5h 51m
Delta
Deal found 6/28$337
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:26 am
TYS
-
BTR
1 stop5h 43m
Delta
Mon 7/207:04 pm
BTR
-
TYS
1 stop3h 48m
Delta
Deal found 6/28$345

Find flight deals from Knoxville to Mississippi

Keep the following information in mind while searching for Knoxville to Mississippi flight deals. Data was last updated July 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$85
(Booking.com)

Popular in

September

Cheapest in

August

Average price

$477
Provider with most accurate pricing for Knoxville McGhee Tyson-Jackson-Evers Intl flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Jackson-Evers Intl flights.
From Knoxville McGhee Tyson to Mississippi
High demand for flights, 1% potential price rise
Cheapest flight prices on average. 6% potential price decrease ($32 potential savings vs. average RT price).
Average for round-trip flights in July 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Knoxville to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Sat 8/15

6:02 pm-11:18 pm

1 stop6h 16m

Memphis

Sat 8/22

9:47 am-4:58 pm

1 stop6h 11m

$275

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Tue 7/28

12:45 pm-10:50 pm

2 stops11h 05m

Memphis

Tue 8/4

2:35 pm-6:55 pm

1 stop3h 20m

$280

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Wed 8/12

1:55 pm-9:45 pm

2 stops8h 50m

Memphis

Sat 8/15

6:45 am-2:40 pm

1 stop6h 55m

$280

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Tue 7/21

8:10 am-3:00 pm

1 stop7h 50m

Memphis

Sat 7/25

6:35 am-7:40 pm

2 stops12h 05m

$286

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Sat 8/8

6:00 am-11:05 am

1 stop6h 05m

Memphis

Mon 8/10

2:22 pm-8:44 pm

1 stop5h 22m

$288

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Sat 8/8

4:55 pm-7:05 pm

1 stop3h 10m

Memphis

Mon 8/10

11:20 am-7:55 pm

1 stop7h 35m

$288

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Mon 8/10

5:15 am-9:33 am

1 stop5h 18m

Memphis

Mon 8/10

5:52 pm-10:58 pm

1 stop4h 06m

$301

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Sat 11/21

5:30 am-10:05 am

1 stop5h 35m

Jackson-Evers Intl

Sat 12/5

5:35 pm-11:46 pm

1 stop5h 11m

$301

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Sat 8/15

12:30 pm-7:05 pm

2 stops7h 35m

Memphis

Mon 8/17

5:15 am-12:20 pm

2 stops6h 05m

$312

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Sat 9/5

5:00 pm-8:52 pm

1 stop4h 52m

Jackson-Evers Intl

Mon 9/7

5:01 pm-11:52 pm

1 stop5h 51m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mississippi

What is the cheapest month to book a flight from Knoxville to Mississippi?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated July 3, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Mississippi. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.8

Boarding

8.1

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.8

Boarding

8.1

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Food

7.2

Entertainment

7.8

Crew

8.5

Comfort

7.8

Boarding

8.1

Overall

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Mississippi?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Mississippi. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Mississippi?

    For as low as $85, Allegiant Air can have you in Mississippi from Knoxville in 1h 19m. The distance between Knoxville and Mississippi is about 341 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Knoxville to Mississippi?

  • Can I find deals for flights from Knoxville to Mississippi that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mississippi.

  • Can I find deals for business class flights from Knoxville to Mississippi?

    Yes. Cheapflights offers flight deals from Knoxville to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mississippi?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $149). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Knoxville to Mississippi

Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$450FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$278Average$416FlexibilityNo cancel feeOn-time71%

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