Mexico City

$372+ Cheap flights from Santa Cruz de la Sierra (VVI) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MEX
Mar 5 — Mar 121
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Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Cheapest flights from Santa Cruz de la Sierra to Mexico City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:25 am
VVI
-
MEX
1 stop10h 25m
LATAM Airlines
Sun 4/123:10 pm
MEX
-
VVI
1 stop11h 25m
LATAM Airlines
Deal found 2/2$658
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/73:40 am
VVI
-
MEX
1 stop16h 30m
Avianca
Sun 3/151:50 pm
MEX
-
VVI
1 stop10h 45m
Avianca
Deal found 2/2$660
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/183:40 am
VVI
-
MEX
1 stop16h 30m
Avianca
Wed 3/251:50 pm
MEX
-
VVI
1 stop10h 45m
Avianca
Deal found 2/3$673
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/13:40 am
VVI
-
MEX
1 stop10h 30m
Avianca
Mon 3/91:50 pm
MEX
-
VVI
1 stop10h 45m
Avianca
Deal found 2/3$674
This Copa Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:15 am
VVI
-
MEX
1 stop19h 50m
Copa Airlines
Fri 4/171:10 pm
MEX
-
VVI
1 stop12h 30m
Copa Airlines
Deal found 2/1$685
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/103:40 am
VVI
-
MEX
1 stop10h 30m
Avianca
Tue 3/171:50 pm
MEX
-
VVI
1 stop10h 45m
Avianca
Deal found 2/2$696
This LATAM Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:25 am
VVI
-
MEX
2 stops26h 05m
Multiple Airlines
Thu 3/194:00 pm
MEX
-
VVI
1 stop10h 35m
Multiple Airlines
Deal found 1/31$704
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:14 am
VVI
-
MEX
1 stop15h 16m
Copa Airlines
Sat 4/412:25 am
MEX
-
VVI
1 stop20h 17m
Copa Airlines
Deal found 2/2$708
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:40 am
VVI
-
MEX
1 stop16h 30m
Avianca
Sat 3/141:50 pm
MEX
-
VVI
1 stop10h 45m
Avianca
Deal found 2/2$715
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/93:40 am
VVI
-
MEX
1 stop25h 20m
Avianca
Tue 2/1711:10 pm
MEX
-
VVI
1 stop25h 25m
Avianca
Deal found 2/1$719
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:40 am
VVI
-
MEX
1 stop21h 15m
Avianca
Wed 2/1811:10 pm
MEX
-
VVI
1 stop25h 25m
Avianca
Deal found 2/1$733

Find flight deals from Santa Cruz de la Sierra to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$658
(FlightHub)

One-way from

$372
(Avianca)

Popular in

January

Cheapest in

September

Average price

$662
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Mexico City Benito Juarez flights.
From Santa Cruz de la Sierra Viru Viru Intl to Mexico City Benito Juarez
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Mexico City Benito Juarez
Highest demand for flights based on searches. 5% potential increase in price ($36 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Mexico City

Route

Depart

Return

Price

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Wed 3/18

3:40 am-6:10 pm

1 stop16h 30m

Mexico City Benito Juarez

Wed 3/25

1:50 pm-2:35 am

1 stop10h 45m

$673

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/31

1:15 am-7:05 pm

1 stop19h 50m

Mexico City Benito Juarez

Fri 4/17

1:10 pm-3:40 am

1 stop12h 30m

$685

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/14

11:48 am-10:05 pm

1 stop12h 17m

Mexico City Benito Juarez

Sat 6/13

1:20 am-10:38 pm

1 stop19h 18m

$685

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/31

1:15 am-7:05 pm

1 stop19h 50m

Mexico City Benito Juarez

Fri 4/10

1:10 pm-3:40 am

1 stop12h 30m

$685

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

3:40 am-12:10 pm

1 stop10h 30m

Mexico City Benito Juarez

Tue 3/17

1:50 pm-2:35 am

1 stop10h 45m

$696

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Fri 3/6

5:25 am-5:30 am

2 stops26h 05m

Mexico City Benito Juarez

Thu 3/19

4:00 pm-4:35 am

1 stop10h 35m

$704

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

1:14 am-12:10 pm

1 stop12h 56m

Mexico City Benito Juarez

Sat 4/4

1:20 am-10:42 pm

1 stop19h 22m

$708

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/5

3:40 am-12:10 pm

1 stop10h 30m

Mexico City Benito Juarez

Fri 3/13

1:50 pm-2:35 am

1 stop10h 45m

$715

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

3:40 am-12:10 pm

1 stop10h 30m

Mexico City Benito Juarez

Thu 3/12

11:10 pm-2:35 am

1 stop25h 25m

$715

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

3:35 am-12:10 pm

1 stop10h 35m

$372

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of $276). Flying from Santa Cruz de la Sierra to Mexico City in November is currently the most expensive (average of $557). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated February 3, 2026.
Get a feel of what it's like to fly with Copa Airlines, LATAM Airlines, and Avianca from Santa Cruz de la Sierra to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.8

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Entertainment

6.8

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Entertainment

6.8

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Entertainment

6.8

Overall

7.6

Comfort

7.4

Boarding

7.8

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    Avianca and Copa Airlines can get you from Santa Cruz de la Sierra to Mexico City in just under 16h 30m. Your travel time can differ by up to 3h 20m. The distance between Santa Cruz de la Sierra and Mexico City is about 3534 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Mexico City round-trip?

    According to our current data, Avianca ($530), LATAM Airlines ($587), and Copa Airlines ($605) offers the cheapest pricing from Santa Cruz de la Sierra to Mexico City. Users have found that Avianca is 19% cheaper than the other options available to this destination.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of $276). Flying from Santa Cruz de la Sierra to Mexico City in November is currently the most expensive (average of $557). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Taxco

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Alternative routes for Santa Cruz de la Sierra to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Santa Cruz de la Sierra to Mexico City

Discover the top 3 airlines that operate flights from Santa Cruz de la Sierra to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$530Average$640FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$587Average$787FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$605Average$799FlexibilityNo cancel feeOn-time70%

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