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$337+ Cheap flights from Santa Cruz de la Sierra (VVI) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MEX
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Mexico City Benito Juarez are usually found in September or August, booked 78 days in advance, depart on a Monday or Saturday and return on a Sunday

Find flight deals from Santa Cruz de la Sierra to Mexico City

Cheapest flights from Santa Cruz de la Sierra to Mexico City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/171:09 amVVI - MEX
1 stop15h 21mCopa Airlines
Wed 11/261:10 pmMEX - VVI
1 stop12h 26mCopa Airlines
Deal found 10/29$558
This Avianca deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/193:40 amVVI - MEX
1 stop16h 30mAvianca
Thu 12/41:50 pmMEX - VVI
1 stop10h 45mAvianca
Deal found 10/30$609
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:40 amVVI - MEX
1 stop15h 20mCopa Airlines
Mon 11/175:55 amMEX - VVI
1 stop19h 41mCopa Airlines
Deal found 10/30$611
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:40 amVVI - MEX
1 stop12h 25mCopa Airlines
Mon 11/109:25 amMEX - VVI
1 stop16h 11mCopa Airlines
Deal found 10/28$623
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:40 amVVI - MEX
1 stop12h 25mCopa Airlines
Wed 12/31:10 pmMEX - VVI
1 stop12h 26mCopa Airlines
Deal found 10/30$639
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:40 amVVI - MEX
1 stop10h 30mAvianca
Sat 11/291:50 pmMEX - VVI
1 stop10h 45mAvianca
Deal found 10/29$653
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/261:09 amVVI - MEX
1 stop13h 01mCopa Airlines
Wed 1/285:55 amMEX - VVI
1 stop14h 55mCopa Airlines
Deal found 10/28$679
This LATAM Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:25 amVVI - MEX
2 stops16h 50mMultiple Airlines
Fri 12/56:50 pmMEX - VVI
2 stops31h 45mMultiple Airlines
Deal found 10/29$682
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/191:09 amVVI - MEX
1 stop20h 11mCopa Airlines
Wed 12/32:00 amMEX - VVI
1 stop18h 46mCopa Airlines
Deal found 10/30$688

Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$558
(Copa Airlines)

One-way from

$337
(Avianca)

Popular in

January

Cheapest in

September

Average price

$686
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Mexico City Benito Juarez flights.
Search Deals
From Santa Cruz de la Sierra Viru Viru Intl to Mexico City Benito Juarez
Search Deals
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Mexico City Benito Juarez
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Mexico City

Route

Depart

Return

Price

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/29

11:40 am-10:00 pm

1 stop12h 20m

Mexico City Benito Juarez

Wed 12/31

9:25 am-10:46 pm

1 stop11h 21m

$558

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/17

1:09 am-7:20 pm

1 stop20h 11m

Mexico City Benito Juarez

Tue 11/25

2:00 am-10:46 pm

1 stop18h 46m

$558

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/29

11:40 am-10:00 pm

1 stop12h 20m

Mexico City Benito Juarez

Sat 11/29

2:00 am-10:46 pm

1 stop18h 46m

$558

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Wed 11/19

3:40 am-6:10 pm

1 stop16h 30m

Mexico City Benito Juarez

Thu 12/4

1:50 pm-2:35 am

1 stop10h 45m

$609

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/18

11:40 am-10:05 pm

1 stop12h 25m

Mexico City Benito Juarez

Mon 11/24

1:20 am-10:46 pm

1 stop19h 26m

$611

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/13

11:40 am-1:00 am

1 stop15h 20m

Mexico City Benito Juarez

Mon 11/17

5:55 am-3:36 am

1 stop19h 41m

$611

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/18

11:40 am-7:20 pm

1 stop9h 40m

Mexico City Benito Juarez

Wed 12/24

3:30 pm-3:36 am

1 stop10h 06m

$623

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/20

11:40 am-1:00 am

1 stop15h 20m

Mexico City Benito Juarez

Thu 12/4

5:55 am-10:46 pm

1 stop14h 51m

$623

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Fri 1/23

3:40 am-6:10 pm

1 stop16h 30m

$337

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Fri 1/23

3:40 am-10:45 am

3 stops33h 05m

$460

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 15 results
1
2

Compare providers for flights from Santa Cruz de la Sierra to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to Mexico City in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Mexico City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Cruz de la Sierra-Mexico City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Mexico City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

How far ahead should I book a flight from Santa Cruz de la Sierra to Mexico City?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Mexico City. Price data was last updated on October 24, 2025.

The price you pay for your flight from Santa Cruz de la Sierra to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 78 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of $276). Flying from Santa Cruz de la Sierra to Mexico City in February is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Copa Airlines, LATAM Airlines, and Avianca from Santa Cruz de la Sierra to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,873 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,467 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    Copa Airlines and Avianca can get you from Santa Cruz de la Sierra to Mexico City in just under 16h 30m. Your travel time can differ by up to 3h 41m. The distance between Santa Cruz de la Sierra and Mexico City is about 3534 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Mexico City round-trip?

    According to our current data, Avianca ($530), Copa Airlines ($554), and LATAM Airlines ($588) offers the cheapest pricing from Santa Cruz de la Sierra to Mexico City. Users have found that Avianca is 20% cheaper than the other options available to this destination.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of $276). Flying from Santa Cruz de la Sierra to Mexico City in February is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santa Cruz de la Sierra to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.
La Paz to Mexico City flights

Top 3 airlines flying from Santa Cruz de la Sierra to Mexico City

Discover the top 3 airlines that operate flights from Santa Cruz de la Sierra to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$530Average$642FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$554Average$676FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$588Average$781FlexibilityNo cancel feeOn-time81%

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