$127+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Apr 16 — Apr 231
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:33 pm
PWM
- PHX
1 stop8h 23m
United Airlines
Wed 4/297:04 pm
PHX
- PWM
2 stops10h 45m
United Airlines
Deal found 3/16![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Wed 6/105:00 am
PHX
- PWM
1 stop9h 07m
American Airlines
Deal found 3/17![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Tue 4/2811:05 pm
PHX
- PWM
2 stops12h 06m
Delta
Deal found 3/15![Delta logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:40 pm
PWM
- PHX
1 stop8h 10m
American Airlines
Wed 4/810:10 pm
PHX
- PWM
1 stop9h 13m
American Airlines
Deal found 3/16![American Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:33 pm
PWM
- PHX
1 stop8h 23m
United Airlines
Tue 4/2811:18 pm
PHX
- PWM
1 stop7h 07m
United Airlines
Deal found 3/14![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Wed 5/69:35 am
PHX
- PWM
2 stops12h 11m
Delta
Deal found 3/16![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:30 pm
PWM
- PHX
1 stop9h 55m
Southwest
Fri 5/810:45 am
PHX
- PWM
2 stops9h 40m
Southwest
Deal found 3/13![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
PWM
- PHX
2 stops11h 28m
United Airlines
Tue 4/2111:18 pm
PHX
- PWM
1 stop7h 07m
United Airlines
Deal found 3/17![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
PWM
- PHX
1 stop10h 00m
American Airlines
Wed 5/137:00 am
PHX
- PWM
1 stop8h 58m
American Airlines
Deal found 3/16![American Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:30 pm
PWM
- PHX
1 stop9h 55m
Southwest
Fri 5/112:50 pm
PHX
- PWM
1 stop7h 35m
Southwest
Deal found 3/15![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:50 pm
PWM
- PHX
1 stop12h 00m
Southwest
Thu 4/1611:00 am
PHX
- PWM
2 stops9h 25m
Southwest
Deal found 3/17![Southwest logo]()
$333
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:42 am
PWM
- PHX
2 stops12h 29m
Delta
Tue 5/510:35 pm
PHX
- PWM
2 stops12h 36m
Delta
Deal found 3/17![Delta logo]()
$328
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:55 pm
PWM
- PHX
2 stops9h 50m
Southwest
Wed 5/139:00 am
PHX
- PWM
2 stops10h 35m
Southwest
Deal found 3/16![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:51 pm
PWM
- PHX
2 stops10h 51m
Delta
Tue 4/2110:35 pm
PHX
- PWM
2 stops12h 36m
Delta
Deal found 3/17![Delta logo]()
$328
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:45 pm
PWM
- PHX
2 stops10h 10m
Southwest
Sun 5/109:00 am
PHX
- PWM
2 stops12h 05m
Southwest
Deal found 3/12![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Fri 5/812:57 am
PHX
- PWM
2 stops12h 10m
Delta
Deal found 3/13![Delta logo]()
$343
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:30 am
PWM
- PHX
2 stops10h 55m
Southwest
Tue 4/1411:55 pm
PHX
- PWM
2 stops9h 25m
Southwest
Deal found 3/17![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:30 am
PWM
- PHX
1 stop20h 16m
Delta
Tue 4/2811:55 pm
PHX
- PWM
2 stops11h 16m
Delta
Deal found 3/14![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:35 am
PWM
- PHX
2 stops10h 00m
Southwest
Fri 6/1911:35 am
PHX
- PWM
2 stops9h 30m
Southwest
Deal found 3/13![Southwest logo]()
$489
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:50 pm
PWM
- PHX
2 stops9h 51m
Delta
Mon 9/77:25 pm
PHX
- PWM
2 stops12h 24m
Delta
Deal found 3/12![Delta logo]()
$460
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:45 am
PWM
- PHX
2 stops9h 55m
Southwest
Thu 6/119:30 am
PHX
- PWM
1 stop11h 35m
Southwest
Deal found 3/12![Southwest logo]()
$544
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:35 pm
PWM
- PHX
1 stop10h 30m
Southwest
Wed 4/16:05 am
PHX
- PWM
1 stop6h 50m
Southwest
Deal found 3/12![Southwest logo]()
$581
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated March 17, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated March 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:40 pm
PWM
- PHX
1 stop8h 10m
American Airlines
Wed 4/810:10 pm
PHX
- PWM
1 stop9h 13m
American Airlines
Deal found 3/16![American Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:50 pm
PWM
- PHX
1 stop12h 00m
Southwest
Thu 4/1611:00 am
PHX
- PWM
2 stops9h 25m
Southwest
Deal found 3/17![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
PWM
- PHX
2 stops11h 28m
United Airlines
Tue 4/2111:18 pm
PHX
- PWM
1 stop7h 07m
United Airlines
Deal found 3/17![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:46 pm
PWM
- PHX
1 stop7h 47m
Delta
Tue 4/2112:10 pm
PHX
- PWM
1 stop9h 36m
Delta
Deal found 3/14![Delta logo]()
$338
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:33 pm
PWM
- PHX
1 stop8h 23m
United Airlines
Tue 4/2811:18 pm
PHX
- PWM
1 stop7h 07m
United Airlines
Deal found 3/14![United Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:33 pm
PWM
- PHX
1 stop8h 23m
United Airlines
Wed 4/297:04 pm
PHX
- PWM
2 stops10h 45m
United Airlines
Deal found 3/16![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:01 pm
PWM
- PHX
1 stop8h 58m
American Airlines
Wed 4/2911:59 pm
PHX
- PWM
1 stop8h 16m
American Airlines
Deal found 3/16![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Tue 4/2811:05 pm
PHX
- PWM
2 stops12h 06m
Delta
Deal found 3/15![Delta logo]()
$313
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:30 pm
PWM
- PHX
1 stop9h 55m
Southwest
Fri 5/112:50 pm
PHX
- PWM
1 stop7h 35m
Southwest
Deal found 3/15![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Wed 5/69:35 am
PHX
- PWM
2 stops12h 11m
Delta
Deal found 3/16![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
PWM
- PHX
1 stop10h 00m
American Airlines
Wed 5/137:00 am
PHX
- PWM
1 stop8h 58m
American Airlines
Deal found 3/16![American Airlines logo]()
$331
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:28 pm
PWM
- PHX
1 stop8h 52m
United Airlines
Deal found 3/17![United Airlines logo]()
$127
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:50 pm
PWM
- PHX
1 stop12h 00m
Southwest
Deal found 3/13![Southwest logo]()
$132
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:55 pm
PWM
- PHX
2 stops10h 31m
Delta
Deal found 3/16![Delta logo]()
$144
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:00 am
PWM
- PHX
1 stop8h 02m
American Airlines
Deal found 3/15![American Airlines logo]()
$146
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:01 pm
PWM
- PHX
1 stop8h 58m
American Airlines
Deal found 3/17![American Airlines logo]()
$157
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:30 pm
PWM
- PHX
2 stops12h 09m
Delta
Deal found 3/17![Delta logo]()
$165
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:50 pm
PWM
- PHX
1 stop8h 16m
American Airlines
Deal found 3/17![American Airlines logo]()
$181
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 am
PWM
- PHX
2 stops11h 15m
Delta
Deal found 3/16![Delta logo]()
$186
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:51 pm
PWM
- PHX
2 stops11h 23m
Delta
Deal found 3/17![Delta logo]()
$195
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:50 pm
PWM
- PHX
1 stop8h 16m
American Airlines
Deal found 3/16![American Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:49 pm
PWM
- PHX
2 stops26h 23m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$210
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:30 am
PWM
- PHX
2 stops10h 10m
Southwest
Deal found 3/17![Southwest logo]()
$211
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated March 17, 2026.
Round-trip from | $309 (United Airlines) |
|---|---|
One-way from | $127 (Southwest) |
Popular in | May |
Cheapest in | July |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 4/28
11:42 am-9:11 pm
2 stops12h 29m
Phoenix Sky Harbor Intl
Tue 5/5
10:35 pm-2:11 pm
2 stops12h 36m
$328
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 4/14
2:51 pm-10:42 pm
2 stops10h 51m
Phoenix Sky Harbor Intl
Tue 4/21
10:35 pm-2:11 pm
2 stops12h 36m
$328
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 4/29
3:55 pm-10:45 pm
2 stops9h 50m
Phoenix Sky Harbor Intl
Wed 5/13
9:00 am-10:35 pm
2 stops10h 35m
$332
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 5/2
4:43 pm-9:40 pm
1 stop7h 57m
Phoenix Sky Harbor Intl
Fri 5/8
12:57 am-4:07 pm
2 stops12h 10m
$343
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/1
12:45 pm-7:55 pm
2 stops10h 10m
Phoenix Sky Harbor Intl
Sun 5/10
9:00 am-12:05 am
2 stops12h 05m
$362
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 4/23
6:30 am-11:46 pm
1 stop20h 16m
Phoenix Sky Harbor Intl
Tue 4/28
11:55 pm-2:11 pm
2 stops11h 16m
$370
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sun 4/5
5:30 am-1:25 pm
2 stops10h 55m
Phoenix Sky Harbor Intl
Tue 4/14
11:55 pm-12:20 pm
2 stops9h 25m
$386
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 9/3
4:50 pm-11:41 pm
2 stops9h 51m
Phoenix Sky Harbor Intl
Mon 9/7
7:25 pm-10:49 am
2 stops12h 24m
$460
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Mon 6/15
5:35 am-12:35 pm
2 stops10h 00m
Phoenix Sky Harbor Intl
Fri 6/19
11:35 am-12:05 am
2 stops9h 30m
$489
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sun 6/7
6:45 am-1:40 pm
2 stops9h 55m
Phoenix Sky Harbor Intl
Thu 6/11
9:30 am-12:05 am
1 stop11h 35m
$544
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How far ahead should I book a flight from Portland, Maine to Mesa?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Mesa. Price data was last updated on March 13, 2026.
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland, Maine to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Portland, Maine to Mesa?
Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Mesa (average of $135). Flying from Portland, Maine to Mesa in August is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 17, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Mesa by cabin class
Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on March 17, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on March 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 4 airlines flying from Portland to Mesa
Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$250 | Average$364 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$450 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$277 | Average$496 | FlexibilityNo cancel fee | On-time63% |