$127+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
May 7 — May 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
PWM
- PHX
1 stop8h 02m
American Airlines
Sun 5/1011:59 pm
PHX
- PWM
1 stop8h 16m
American Airlines
Deal found 4/7![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:48 am
PWM
- PHX
2 stops9h 21m
Delta
Fri 6/1910:57 pm
PHX
- PWM
2 stops12h 22m
Delta
Deal found 4/6![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:10 am
PWM
- PHX
2 stops9h 50m
Southwest
Sat 5/911:45 am
PHX
- PWM
1 stop8h 25m
Southwest
Deal found 4/6![Southwest logo]()
$323
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:51 pm
PWM
- PHX
2 stops11h 33m
Delta
Sat 5/95:45 am
PHX
- PWM
1 stop15h 58m
Delta
Deal found 4/5![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:50 pm
PWM
- PHX
1 stop10h 00m
Southwest
Tue 5/125:55 am
PHX
- PWM
1 stop6h 25m
Southwest
Deal found 4/6![Southwest logo]()
$326
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Fri 5/85:45 am
PHX
- PWM
1 stop15h 58m
Delta
Deal found 4/5![Delta logo]()
$330
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:45 pm
PWM
- PHX
2 stops10h 10m
Southwest
Tue 5/125:55 am
PHX
- PWM
1 stop6h 25m
Southwest
Deal found 4/6![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
PWM
- PHX
1 stop8h 02m
American Airlines
Wed 5/610:22 am
PHX
- PWM
1 stop9h 24m
American Airlines
Deal found 4/6![American Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:48 am
PWM
- PHX
2 stops9h 21m
Delta
Sun 6/1412:41 am
PHX
- PWM
1 stop7h 02m
Delta
Deal found 4/7![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:50 am
PWM
- PHX
1 stop10h 30m
American Airlines
Wed 5/611:32 pm
PHX
- PWM
1 stop7h 46m
American Airlines
Deal found 4/4![American Airlines logo]()
$334
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:50 pm
PWM
- PHX
1 stop10h 00m
Southwest
Mon 5/185:05 am
PHX
- PWM
1 stop8h 10m
Southwest
Deal found 4/7![Southwest logo]()
$346
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:50 pm
PWM
- PHX
1 stop10h 03m
United Airlines
Mon 5/1811:30 pm
PHX
- PWM
1 stop7h 53m
United Airlines
Deal found 4/5![United Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:21 am
PWM
- PHX
2 stops13h 57m
Delta
Wed 5/610:35 pm
PHX
- PWM
2 stops10h 20m
Delta
Deal found 4/6![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:30 am
PWM
- PHX
2 stops12h 10m
United Airlines
Tue 5/1211:47 pm
PHX
- PWM
1 stop7h 31m
United Airlines
Deal found 4/3![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:10 am
PWM
- PHX
2 stops9h 55m
Southwest
Wed 6/310:30 pm
PHX
- PWM
1 stop8h 15m
Southwest
Deal found 4/4![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:20 pm
PWM
- PHX
1 stop9h 15m
Southwest
Fri 6/511:55 pm
PHX
- PWM
1 stop13h 20m
Southwest
Deal found 4/4![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:50 pm
PWM
- PHX
1 stop10h 03m
United Airlines
Wed 5/66:44 pm
PHX
- PWM
2 stops11h 05m
United Airlines
Deal found 4/4![United Airlines logo]()
$421
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:45 pm
PWM
- PHX
2 stops10h 10m
Southwest
Sun 5/312:05 pm
PHX
- PWM
2 stops9h 00m
Southwest
Deal found 4/6![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:45 pm
PWM
- PHX
2 stops10h 10m
Southwest
Sun 5/1710:50 am
PHX
- PWM
2 stops10h 15m
Southwest
Deal found 4/6![Southwest logo]()
$493
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated April 7, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:55 pm
PWM
- PHX
1 stop9h 00m
Southwest
Sat 5/911:45 am
PHX
- PWM
1 stop8h 25m
Southwest
Deal found 4/6![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:45 pm
PWM
- PHX
2 stops10h 10m
Southwest
Tue 5/125:55 am
PHX
- PWM
1 stop6h 25m
Southwest
Deal found 4/6![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Mon 5/410:55 pm
PHX
- PWM
1 stop22h 51m
Delta
Deal found 4/5![Delta logo]()
$330
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Wed 5/610:35 pm
PHX
- PWM
2 stops10h 25m
Delta
Deal found 4/3![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:51 pm
PWM
- PHX
2 stops11h 33m
Delta
Sat 5/95:45 am
PHX
- PWM
1 stop15h 58m
Delta
Deal found 4/5![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:50 am
PWM
- PHX
1 stop10h 30m
American Airlines
Wed 5/611:32 pm
PHX
- PWM
1 stop7h 46m
American Airlines
Deal found 4/4![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
PWM
- PHX
1 stop8h 02m
American Airlines
Sun 5/1011:59 pm
PHX
- PWM
1 stop8h 16m
American Airlines
Deal found 4/7![American Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
PWM
- PHX
1 stop8h 02m
American Airlines
Wed 5/610:22 am
PHX
- PWM
1 stop9h 24m
American Airlines
Deal found 4/6![American Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:50 pm
PWM
- PHX
1 stop10h 00m
Southwest
Tue 5/125:55 am
PHX
- PWM
1 stop6h 25m
Southwest
Deal found 4/6![Southwest logo]()
$326
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:57 am
PWM
- PHX
1 stop10h 37m
American Airlines
Deal found 4/6![American Airlines logo]()
$127
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Deal found 4/6![Delta logo]()
$129
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:40 am
PWM
- PHX
2 stops10h 00m
Southwest
Deal found 4/7![Southwest logo]()
$132
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
- PHX
2 stops9h 55m
Delta
Deal found 4/6![Delta logo]()
$134
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
PWM
- PHX
2 stops15h 35m
Southwest
Deal found 4/6![Southwest logo]()
$138
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:43 pm
PWM
- PHX
1 stop7h 57m
Delta
Deal found 4/7![Delta logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:49 pm
PWM
- PHX
1 stop26h 12m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$142
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:51 pm
PWM
- PHX
2 stops11h 33m
Delta
Deal found 4/7![Delta logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:06 pm
PWM
- PHX
3 stops21h 03m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:01 pm
PWM
- PHX
2 stops32h 20m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:57 am
PWM
- PHX
1 stop15h 13m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$168
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:30 pm
PWM
- PHX
1 stop9h 55m
Southwest
Deal found 4/3![Southwest logo]()
$172
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated April 7, 2026.
Round-trip from | $310 (American Airlines) |
|---|---|
One-way from | $127 (American Airlines) |
Popular in | May |
Cheapest in | June |
Average price | $455 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/15
4:50 pm-11:50 pm
1 stop10h 00m
Phoenix Sky Harbor Intl
Mon 5/18
5:05 am-4:15 pm
1 stop8h 10m
$346
Quickest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/15
4:50 pm-11:53 pm
1 stop10h 03m
Phoenix Sky Harbor Intl
Mon 5/18
11:30 pm-10:23 am
1 stop7h 53m
$363
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 5/9
5:30 am-2:40 pm
2 stops12h 10m
Phoenix Sky Harbor Intl
Tue 5/12
11:47 pm-10:18 am
1 stop7h 31m
$368
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 6/2
6:10 am-1:05 pm
2 stops9h 55m
Phoenix Sky Harbor Intl
Wed 6/3
10:30 pm-9:45 am
1 stop8h 15m
$381
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 6/4
5:20 pm-11:35 pm
1 stop9h 15m
Phoenix Sky Harbor Intl
Fri 6/5
11:55 pm-4:15 pm
1 stop13h 20m
$397
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sun 5/3
5:21 am-4:18 pm
2 stops13h 57m
Phoenix Sky Harbor Intl
Wed 5/6
10:35 pm-11:55 am
2 stops10h 20m
$419
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sun 5/3
4:50 pm-11:53 pm
1 stop10h 03m
Phoenix Sky Harbor Intl
Wed 5/6
6:44 pm-8:49 am
2 stops11h 05m
$421
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/1
12:45 pm-7:55 pm
2 stops10h 10m
Phoenix Sky Harbor Intl
Sun 5/3
12:05 pm-12:05 am
2 stops9h 00m
$428
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/15
12:45 pm-7:55 pm
2 stops10h 10m
Phoenix Sky Harbor Intl
Sun 5/17
10:50 am-12:05 am
2 stops10h 15m
$493
Cheapest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/15
4:50 pm-11:50 pm
1 stop10h 00m
$127
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How far ahead should I book a flight from Portland, Maine to Mesa?
Use this chart to determine the optimal time to book a round-trip flight from Portland to Mesa. Price data was last updated on April 3, 2026.
Booking 76 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland, Maine to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Portland, Maine to Mesa?
Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Mesa (average of $135). Flying from Portland, Maine to Mesa in August is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated April 7, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Portland
Popular flights
Top destinations
Alternative routes for Portland to Mesa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Mesa by cabin class
Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on April 7, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on April 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 4 airlines flying from Portland to Mesa
Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$403 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$251 | Average$383 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$263 | Average$463 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$495 | FlexibilityNo cancel fee | On-time63% |