$181+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
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Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:48 am
PWM
- PHX
1 stop8h 06m
Delta
Tue 7/710:14 am
PHX
- PWM
1 stop10h 00m
Delta
Deal found 5/9![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:54 pm
PWM
- PHX
1 stop8h 04m
American Airlines
Sat 6/205:06 am
PHX
- PWM
1 stop10h 19m
American Airlines
Deal found 5/7![American Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
PWM
- PHX
1 stop9h 17m
Delta
Mon 6/88:09 pm
PHX
- PWM
2 stops11h 34m
Delta
Deal found 5/11![Delta logo]()
$366
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:54 pm
PWM
- PHX
1 stop8h 04m
American Airlines
Tue 6/165:00 am
PHX
- PWM
1 stop9h 06m
American Airlines
Deal found 5/11![American Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:54 pm
PWM
- PHX
1 stop9h 45m
American Airlines
Mon 10/55:00 am
PHX
- PWM
1 stop8h 43m
American Airlines
Deal found 5/10![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:50 pm
PWM
- PHX
1 stop8h 16m
American Airlines
Mon 9/2811:49 pm
PHX
- PWM
1 stop8h 59m
American Airlines
Deal found 5/7![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:24 pm
PWM
- PHX
1 stop10h 36m
American Airlines
Wed 6/31:12 pm
PHX
- PWM
1 stop7h 39m
American Airlines
Deal found 5/10![American Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:15 am
PWM
- PHX
1 stop8h 48m
American Airlines
Sat 5/3012:50 am
PHX
- PWM
1 stop7h 56m
American Airlines
Deal found 5/7![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Mon 6/85:00 am
PHX
- PWM
1 stop9h 06m
American Airlines
Deal found 5/11![American Airlines logo]()
$383
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:05 am
PWM
- PHX
2 stops12h 38m
Delta
Mon 6/88:09 pm
PHX
- PWM
2 stops11h 34m
Delta
Deal found 5/11![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:10 pm
PWM
- PHX
1 stop7h 00m
Southwest
Fri 6/1211:35 am
PHX
- PWM
2 stops9h 30m
Southwest
Deal found 5/8![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:48 am
PWM
- PHX
2 stops9h 23m
Delta
Mon 6/1510:57 pm
PHX
- PWM
2 stops12h 22m
Delta
Deal found 5/11![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:55 pm
PWM
- PHX
1 stop8h 25m
Southwest
Sun 6/710:25 pm
PHX
- PWM
1 stop8h 20m
Southwest
Deal found 5/11![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:55 pm
PWM
- PHX
1 stop10h 04m
Delta
Tue 6/167:15 am
PHX
- PWM
2 stops13h 14m
Delta
Deal found 5/9![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:48 am
PWM
- PHX
1 stop7h 29m
Delta
Tue 6/167:15 am
PHX
- PWM
2 stops13h 14m
Delta
Deal found 5/10![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:40 pm
PWM
- PHX
2 stops10h 30m
Delta
Sat 6/209:45 am
PHX
- PWM
2 stops12h 07m
Delta
Deal found 5/10![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/64:49 pm
PWM
- PHX
1 stop7h 18m
Delta
Sat 6/139:45 am
PHX
- PWM
2 stops12h 07m
Delta
Deal found 5/7![Delta logo]()
$435
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated May 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:57 am
PWM
- PHX
1 stop10h 28m
American Airlines
Fri 5/2910:55 pm
PHX
- PWM
1 stop7h 56m
American Airlines
Deal found 5/10![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:24 pm
PWM
- PHX
1 stop10h 36m
American Airlines
Wed 6/31:12 pm
PHX
- PWM
1 stop7h 39m
American Airlines
Deal found 5/10![American Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:15 am
PWM
- PHX
1 stop8h 48m
American Airlines
Sat 5/3012:50 am
PHX
- PWM
1 stop7h 56m
American Airlines
Deal found 5/7![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
PWM
- PHX
1 stop9h 17m
Delta
Mon 6/88:09 pm
PHX
- PWM
2 stops11h 34m
Delta
Deal found 5/11![Delta logo]()
$366
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Mon 6/85:06 am
PHX
- PWM
1 stop10h 19m
American Airlines
Deal found 5/11![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Mon 6/85:00 am
PHX
- PWM
1 stop9h 06m
American Airlines
Deal found 5/11![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:55 pm
PWM
- PHX
1 stop9h 35m
Southwest
Sat 6/131:35 pm
PHX
- PWM
1 stop7h 05m
Southwest
Deal found 5/7![Southwest logo]()
$390
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:54 pm
PWM
- PHX
1 stop8h 04m
American Airlines
Tue 6/165:00 am
PHX
- PWM
1 stop9h 06m
American Airlines
Deal found 5/11![American Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:54 pm
PWM
- PHX
1 stop8h 04m
American Airlines
Sat 6/205:06 am
PHX
- PWM
1 stop10h 19m
American Airlines
Deal found 5/7![American Airlines logo]()
$364
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:31 pm
PWM
- PHX
1 stop9h 28m
United Airlines
Deal found 5/9![United Airlines logo]()
$181
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:05 pm
PWM
- PHX
2 stops12h 24m
Delta
Deal found 5/9![Delta logo]()
$186
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 am
PWM
- PHX
1 stop8h 04m
American Airlines
Deal found 5/7![American Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
PWM
- PHX
1 stop9h 12m
Delta
Deal found 5/7![Delta logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:44 pm
PWM
- PHX
3 stops32h 46m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Deal found 5/7![American Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:20 pm
PWM
- PHX
2 stops9h 50m
Southwest
Deal found 5/11![Southwest logo]()
$238
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:36 pm
PWM
- PHX
2 stops12h 57m
American Airlines
Deal found 5/7![American Airlines logo]()
$241
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:20 pm
PWM
- PHX
2 stops9h 50m
Southwest
Deal found 5/7![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:15 am
PWM
- PHX
2 stops10h 11m
United Airlines
Deal found 5/7![United Airlines logo]()
$246
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:45 pm
PWM
- PHX
2 stops10h 05m
Southwest
Deal found 5/7![Southwest logo]()
$249
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated May 12, 2026.
Round-trip from | $361 (Delta) |
|---|---|
One-way from | $181 (United Airlines) |
Popular in | May |
Cheapest in | January |
Average price | $507 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 6/6
8:05 am-5:43 pm
2 stops12h 38m
Phoenix Sky Harbor Intl
Mon 6/8
8:09 pm-10:43 am
2 stops11h 34m
$372
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Mon 6/8
11:48 am-6:11 pm
2 stops9h 23m
Phoenix Sky Harbor Intl
Mon 6/15
10:57 pm-2:19 pm
2 stops12h 22m
$372
Quickest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 6/10
7:10 pm-11:10 pm
1 stop7h 00m
Phoenix Sky Harbor Intl
Fri 6/12
11:35 am-12:05 am
2 stops9h 30m
$395
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 6/6
3:55 pm-9:20 pm
1 stop8h 25m
Phoenix Sky Harbor Intl
Sun 6/7
10:25 pm-9:45 am
1 stop8h 20m
$395
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 6/11
1:55 pm-8:59 pm
1 stop10h 04m
Phoenix Sky Harbor Intl
Tue 6/16
7:15 am-11:29 pm
2 stops13h 14m
$395
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 6/9
11:48 am-4:17 pm
1 stop7h 29m
Phoenix Sky Harbor Intl
Tue 6/16
7:15 am-11:29 pm
2 stops13h 14m
$395
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 6/16
12:40 pm-8:10 pm
2 stops10h 30m
Phoenix Sky Harbor Intl
Sat 6/20
9:45 am-12:52 am
2 stops12h 07m
$424
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 6/6
4:49 pm-9:07 pm
1 stop7h 18m
Phoenix Sky Harbor Intl
Sat 6/13
9:45 am-12:52 am
2 stops12h 07m
$435
Cheapest one-way
Quickest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 6/17
7:10 pm-11:10 pm
1 stop7h 00m
$181
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 6/5
2:38 pm-11:29 pm
2 stops11h 51m
$186
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated May 12, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on May 12, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on May 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 4 airlines flying from Portland to Mesa
Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$417 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$468 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$253 | Average$409 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$478 | FlexibilityNo cancel fee | On-time63% |