$181+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Jun 3 — Jun 101
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
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Best
Last-minute
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Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:58 am
PWM
- PHX
1 stop7h 59m
American Airlines
Wed 6/105:06 am
PHX
- PWM
1 stop10h 19m
American Airlines
Deal found 4/30![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:42 am
PWM
- PHX
1 stop9h 10m
American Airlines
Fri 5/291:02 pm
PHX
- PWM
1 stop7h 49m
American Airlines
Deal found 5/1![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:15 am
PWM
- PHX
1 stop10h 24m
American Airlines
Fri 5/2911:36 pm
PHX
- PWM
1 stop7h 15m
American Airlines
Deal found 5/1![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:48 am
PWM
- PHX
1 stop7h 29m
Delta
Tue 6/1611:51 am
PHX
- PWM
2 stops10h 01m
Delta
Deal found 4/29![Delta logo]()
$366
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Tue 6/1612:15 pm
PHX
- PWM
1 stop7h 31m
American Airlines
Deal found 4/30![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
PWM
- PHX
1 stop9h 03m
Delta
Mon 8/1011:15 pm
PHX
- PWM
1 stop21h 44m
Delta
Deal found 4/29![Delta logo]()
$377
This deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:50 pm
PWM
- PHX
1 stop7h 53m
Delta
Tue 6/166:00 am
PHX
- PWM
1 stop6h 55m
Delta
Deal found 5/2![Delta logo]()
$380
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:29 pm
PWM
- PHX
1 stop10h 02m
American Airlines
Sat 11/712:59 am
PHX
- PWM
1 stop8h 50m
American Airlines
Deal found 5/1![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
PWM
- PHX
2 stops13h 04m
Delta
Mon 8/106:00 am
PHX
- PWM
1 stop14h 59m
Delta
Deal found 4/29![Delta logo]()
$382
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:36 pm
PWM
- PHX
1 stop8h 57m
American Airlines
Mon 6/85:00 am
PHX
- PWM
1 stop9h 06m
American Airlines
Deal found 5/4![American Airlines logo]()
$384
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:55 pm
PWM
- PHX
1 stop10h 04m
Delta
Tue 6/169:43 am
PHX
- PWM
2 stops12h 09m
Delta
Deal found 4/30![Delta logo]()
$366
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:10 am
PWM
- PHX
1 stop9h 05m
Southwest
Fri 5/2910:45 am
PHX
- PWM
2 stops9h 40m
Southwest
Deal found 5/1![Southwest logo]()
$405
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
PWM
- PHX
1 stop8h 01m
United Airlines
Wed 9/29:00 am
PHX
- PWM
1 stop10h 01m
United Airlines
Deal found 5/3![United Airlines logo]()
$471
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:50 pm
PWM
- PHX
1 stop7h 53m
Delta
Sat 6/69:33 am
PHX
- PWM
2 stops12h 10m
Delta
Deal found 5/2![Delta logo]()
$366
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:48 am
PWM
- PHX
1 stop7h 29m
Delta
Tue 6/1611:51 am
PHX
- PWM
2 stops10h 01m
Delta
Deal found 4/29![Delta logo]()
$366
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:55 am
PWM
- PHX
2 stops9h 00m
Southwest
Fri 9/411:10 pm
PHX
- PWM
1 stop9h 35m
Southwest
Deal found 5/1![Southwest logo]()
$454
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:00 pm
PWM
- PHX
2 stops10h 47m
Delta
Tue 10/612:05 pm
PHX
- PWM
1 stop7h 18m
Delta
Deal found 4/30![Delta logo]()
$465
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated May 4, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated May 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:54 pm
PWM
- PHX
1 stop8h 04m
American Airlines
Mon 5/2511:05 pm
PHX
- PWM
1 stop8h 27m
American Airlines
Deal found 4/30![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:03 pm
PWM
- PHX
1 stop8h 12m
United Airlines
Sat 5/3011:50 pm
PHX
- PWM
2 stops10h 35m
United Airlines
Deal found 5/1![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:40 am
PWM
- PHX
2 stops15h 35m
Southwest
Mon 6/111:55 pm
PHX
- PWM
2 stops9h 25m
Southwest
Deal found 5/1![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:05 pm
PWM
- PHX
1 stop7h 37m
American Airlines
Mon 6/15:00 am
PHX
- PWM
1 stop9h 07m
American Airlines
Deal found 5/1![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:15 am
PWM
- PHX
1 stop8h 48m
American Airlines
Fri 5/291:02 pm
PHX
- PWM
1 stop7h 49m
American Airlines
Deal found 4/30![American Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:50 pm
PWM
- PHX
1 stop7h 53m
Delta
Fri 5/2910:55 pm
PHX
- PWM
2 stops9h 20m
Delta
Deal found 4/30![Delta logo]()
$366
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:10 am
PWM
- PHX
1 stop9h 05m
Southwest
Sat 5/3011:25 am
PHX
- PWM
2 stops8h 45m
Southwest
Deal found 4/30![Southwest logo]()
$414
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:15 am
PWM
- PHX
1 stop10h 24m
American Airlines
Fri 5/2911:36 pm
PHX
- PWM
1 stop7h 15m
American Airlines
Deal found 5/1![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:10 am
PWM
- PHX
1 stop9h 05m
Southwest
Fri 5/2910:45 am
PHX
- PWM
2 stops9h 40m
Southwest
Deal found 5/1![Southwest logo]()
$405
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:50 pm
PWM
- PHX
1 stop8h 50m
Southwest
Mon 6/111:55 pm
PHX
- PWM
2 stops9h 25m
Southwest
Deal found 4/30![Southwest logo]()
$395
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:25 pm
PWM
- PHX
1 stop8h 12m
United Airlines
Deal found 4/30![United Airlines logo]()
$181
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 am
PWM
- PHX
2 stops11h 24m
United Airlines
Deal found 5/3![United Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:16 pm
PWM
- PHX
3 stops32h 17m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$188
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:59 pm
PWM
- PHX
1 stop8h 00m
American Airlines
Deal found 5/3![American Airlines logo]()
$191
This JetBlue deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:37 pm
PWM
- PHX
1 stop11h 16m
JetBlue
Deal found 5/1![JetBlue logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
PWM
- PHX
3 stops31h 42m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:56 pm
PWM
- PHX
2 stops27h 37m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:27 am
PWM
- PHX
1 stop10h 01m
American Airlines
Deal found 5/2![American Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:34 pm
PWM
- PHX
1 stop7h 40m
American Airlines
Deal found 5/3![American Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:16 pm
PWM
- PHX
3 stops35h 13m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$203
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated May 4, 2026.
Round-trip from | $361 (American Airlines) |
|---|---|
One-way from | $181 (United Airlines) |
Popular in | May |
Cheapest in | July |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 6/11
1:55 pm-8:59 pm
1 stop10h 04m
Phoenix Sky Harbor Intl
Tue 6/16
9:43 am-12:52 am
2 stops12h 09m
$366
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 5/30
12:50 pm-5:43 pm
1 stop7h 53m
Phoenix Sky Harbor Intl
Sat 6/6
9:33 am-12:43 am
2 stops12h 10m
$366
Quickest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 6/9
11:48 am-4:17 pm
1 stop7h 29m
Phoenix Sky Harbor Intl
Tue 6/16
11:51 am-12:52 am
2 stops10h 01m
$366
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 5/27
6:10 am-12:15 pm
1 stop9h 05m
Phoenix Sky Harbor Intl
Fri 5/29
10:45 am-11:25 pm
2 stops9h 40m
$405
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Mon 8/31
5:55 am-11:55 am
2 stops9h 00m
Phoenix Sky Harbor Intl
Fri 9/4
11:10 pm-11:45 am
1 stop9h 35m
$454
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 9/26
3:00 pm-10:47 pm
2 stops10h 47m
Phoenix Sky Harbor Intl
Tue 10/6
12:05 pm-10:23 pm
1 stop7h 18m
$465
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 9/1
6:00 am-11:01 am
1 stop8h 01m
Phoenix Sky Harbor Intl
Wed 9/2
9:00 am-10:01 pm
1 stop10h 01m
$471
Cheapest one-way
Quickest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 6/23
7:10 pm-11:10 pm
1 stop7h 00m
$181
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 5/22
6:25 pm-11:37 pm
1 stop8h 12m
$181
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sat 6/6
12:50 pm-9:21 pm
2 stops11h 31m
$186
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated May 4, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Portland to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on May 4, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on May 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 4 airlines flying from Portland to Mesa
Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$417 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$252 | Average$463 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$482 | FlexibilityNo cancel fee | On-time63% |