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Mesa

$146+ Cheap flights from Portland, ME (PWM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Portland to Mesa

Cheapest flights from Portland to Mesa
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
PWM
-
PHX
1 stop8h 02m
American Airlines
Wed 5/611:32 pm
PHX
-
PWM
1 stop7h 46m
American Airlines
Deal found 3/18$328
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:48 pm
PWM
-
PHX
1 stop8h 06m
Delta
Wed 4/1511:05 pm
PHX
-
PWM
2 stops12h 06m
Delta
Deal found 3/18$331
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/54:43 pm
PWM
-
PHX
2 stops9h 45m
Delta
Fri 5/810:55 pm
PHX
-
PWM
2 stops12h 03m
Delta
Deal found 3/18$337
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:43 pm
PWM
-
PHX
1 stop7h 57m
Delta
Wed 5/610:35 pm
PHX
-
PWM
2 stops10h 25m
Delta
Deal found 3/19$350
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:33 pm
PWM
-
PHX
1 stop8h 23m
United Airlines
Wed 4/297:04 pm
PHX
-
PWM
2 stops10h 45m
United Airlines
Deal found 3/21$353
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:57 am
PWM
-
PHX
1 stop9h 07m
American Airlines
Sun 5/1011:32 pm
PHX
-
PWM
1 stop7h 46m
American Airlines
Deal found 3/20$361
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:50 pm
PWM
-
PHX
1 stop12h 00m
Southwest
Thu 4/1612:50 pm
PHX
-
PWM
1 stop7h 35m
Southwest
Deal found 3/18$366
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
PWM
-
PHX
1 stop8h 02m
American Airlines
Mon 6/15:00 am
PHX
-
PWM
1 stop9h 07m
American Airlines
Deal found 3/18$368
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:01 pm
PWM
-
PHX
1 stop8h 58m
American Airlines
Wed 4/2911:32 pm
PHX
-
PWM
1 stop7h 51m
American Airlines
Deal found 3/18$370

Find flight deals from Portland to Mesa

Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated March 23, 2026.

Round-trip from

$328
(American Airlines)

One-way from

$146
(United Airlines)

Popular in

May

Cheapest in

July

Average price

$456
From Portland to Mesa
Search Deals
One-way flight from Portland to Mesa
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Mon 4/20

6:33 pm-11:56 pm

1 stop8h 23m

Phoenix Sky Harbor Intl

Wed 4/29

7:04 pm-8:49 am

2 stops10h 45m

$353
Quickest round-trip

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 5/9

9:20 am-3:15 pm

1 stop8h 55m

Phoenix Sky Harbor Intl

Tue 5/12

11:47 pm-10:18 am

1 stop7h 31m

$401

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 8/8

6:30 am-2:45 pm

2 stops11h 15m

Phoenix Sky Harbor Intl

Sat 8/15

10:00 am-10:33 pm

1 stop9h 33m

$416

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Fri 5/15

12:45 pm-7:55 pm

2 stops10h 10m

Phoenix Sky Harbor Intl

Tue 5/19

9:50 am-10:35 pm

2 stops9h 45m

$421

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 4/11

2:30 pm-11:46 pm

2 stops12h 16m

Phoenix Sky Harbor Intl

Wed 4/15

10:35 pm-2:11 pm

2 stops12h 36m

$423

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Fri 5/1

12:45 pm-8:15 pm

2 stops10h 30m

Phoenix Sky Harbor Intl

Sun 5/10

9:00 am-12:05 am

2 stops12h 05m

$440

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Fri 4/10

6:00 am-11:02 am

1 stop8h 02m

Phoenix Sky Harbor Intl

Mon 4/13

11:59 pm-12:38 pm

1 stop9h 39m

$447

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Wed 6/24

7:10 pm-11:10 pm

1 stop7h 00m

Phoenix Sky Harbor Intl

Wed 7/1

9:05 am-10:55 pm

2 stops10h 50m

$451

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 4/4

1:10 pm-6:20 pm

1 stop8h 10m

Phoenix Sky Harbor Intl

Mon 4/13

11:55 pm-12:20 pm

2 stops9h 25m

$452

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Mon 4/20

4:50 pm-11:50 pm

1 stop10h 00m

Phoenix Sky Harbor Intl

Wed 4/29

9:50 am-10:35 pm

2 stops9h 45m

$464

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Portland to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Mesa

How far ahead should I book a flight from Portland, Maine to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Mesa. Price data was last updated on March 13, 2026.

Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland, Maine to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland, Maine to Mesa?

Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Mesa (average of $135). Flying from Portland, Maine to Mesa in August is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 23, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,319 reviews
Southwest
8.0
Very good
4,324 reviews

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,461 reviews
Southwest
8.0
Very good
4,324 reviews

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,489 reviews
Southwest
8.0
Very good
4,324 reviews

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Mesa?

    Located just 2.9 mi from the city center, Portland is the airport most travelers will use when flying to Mesa from Portland. Booking flights from Portland (PWM) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 4 different airlines.

  • How long is the flight from Portland, Maine to Mesa?

    There are many flights that can get you from Portland, Maine to Mesa in 8h 23m. Fly via United Airlines, Delta, or Southwest to get the fastest option. The distance between Portland, Maine and Mesa is about 2332 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $108. Users have also found prices from $125 and $138 on United Airlines and Southwest, respectively.

  • Can I find deals for flights from Portland to Mesa that include hotel bookings?

    Yes. In addition to deals on Portland to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Mesa.

  • Can I find deals for business class flights from Portland to Mesa?

    Yes. Cheapflights offers flight deals from Portland to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Mesa?

    Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Mesa (average of $135). Flying from Portland, Maine to Mesa in August is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Portland to Mesa

Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$230Average$417FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$367FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$263Average$451FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$291Average$495FlexibilityNo cancel feeOn-time63%

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