$131+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Jul 21 — Jul 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Sat 9/511:06 pm
PHX
- PWM
1 stop10h 15m
JetBlue
Deal found 6/18![JetBlue logo]()
$241
This flygcity.se deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:49 pm
PWM
- PHX
1 stop9h 54m
JetBlue
Sun 8/1611:06 pm
PHX
- PWM
1 stop10h 15m
JetBlue
Deal found 6/18![JetBlue logo]()
$247
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Sat 8/2911:06 pm
PHX
- PWM
1 stop10h 15m
JetBlue
Deal found 6/19![JetBlue logo]()
$355
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:00 am
PWM
- PHX
1 stop7h 59m
American Airlines
Sat 8/2211:45 pm
PHX
- PWM
1 stop8h 53m
American Airlines
Deal found 6/20![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:15 pm
PWM
- PHX
1 stop7h 05m
Southwest
Wed 8/2610:35 am
PHX
- PWM
2 stops8h 30m
Southwest
Deal found 6/17![Southwest logo]()
$382
This JetBlue deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
PWM
- PHX
1 stop9h 25m
JetBlue
Sat 10/31:20 pm
PHX
- PWM
1 stop7h 32m
JetBlue
Deal found 6/19![JetBlue logo]()
$387
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:45 am
PWM
- PHX
2 stops8h 15m
Southwest
Sat 8/2211:10 pm
PHX
- PWM
1 stop8h 25m
Southwest
Deal found 6/20![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:40 pm
PWM
- PHX
2 stops9h 15m
Southwest
Sat 8/299:45 am
PHX
- PWM
1 stop8h 15m
Southwest
Deal found 6/19![Southwest logo]()
$395
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Wed 7/2911:06 pm
PHX
- PWM
1 stop22h 10m
JetBlue
Deal found 6/18![JetBlue logo]()
$396
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:30 am
PWM
- PHX
2 stops9h 20m
Southwest
Tue 10/2012:35 am
PHX
- PWM
2 stops9h 15m
Southwest
Deal found 6/18![Southwest logo]()
$400
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:46 am
PWM
- PHX
1 stop9h 35m
American Airlines
Thu 12/1011:10 am
PHX
- PWM
1 stop9h 24m
American Airlines
Deal found 6/20![American Airlines logo]()
$403
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:00 am
PWM
- PHX
1 stop7h 59m
American Airlines
Sat 8/2211:45 pm
PHX
- PWM
1 stop8h 53m
American Airlines
Deal found 6/20![American Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:15 pm
PWM
- PHX
1 stop7h 05m
Southwest
Wed 8/2610:35 am
PHX
- PWM
2 stops8h 30m
Southwest
Deal found 6/17![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:15 am
PWM
- PHX
2 stops10h 11m
United Airlines
Mon 7/278:50 am
PHX
- PWM
1 stop7h 37m
United Airlines
Deal found 6/19![United Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:45 am
PWM
- PHX
2 stops8h 15m
Southwest
Sat 8/2211:10 pm
PHX
- PWM
1 stop8h 25m
Southwest
Deal found 6/20![Southwest logo]()
$390
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:59 pm
PWM
- PHX
1 stop8h 00m
American Airlines
Mon 7/2012:15 pm
PHX
- PWM
1 stop7h 21m
American Airlines
Deal found 6/16![American Airlines logo]()
$432
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:45 am
PWM
- PHX
1 stop14h 20m
Southwest
Tue 8/1110:35 am
PHX
- PWM
2 stops8h 30m
Southwest
Deal found 6/20![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:40 am
PWM
- PHX
2 stops12h 30m
United Airlines
Sat 9/511:28 am
PHX
- PWM
1 stop6h 55m
United Airlines
Deal found 6/18![United Airlines logo]()
$500
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 am
PWM
- PHX
2 stops9h 30m
Southwest
Mon 7/278:20 pm
PHX
- PWM
2 stops10h 35m
Southwest
Deal found 6/19![Southwest logo]()
$483
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:30 am
PWM
- PHX
2 stops10h 10m
Southwest
Mon 7/208:20 pm
PHX
- PWM
2 stops10h 35m
Southwest
Deal found 6/16![Southwest logo]()
$497
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated June 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:24 pm
PWM
- PHX
1 stop14h 08m
American Airlines
Tue 7/1411:52 pm
PHX
- PWM
1 stop9h 19m
American Airlines
Deal found 6/16![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:24 pm
PWM
- PHX
1 stop7h 50m
American Airlines
Tue 7/2112:15 pm
PHX
- PWM
1 stop7h 21m
American Airlines
Deal found 6/18![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:59 pm
PWM
- PHX
1 stop8h 00m
American Airlines
Mon 7/206:20 am
PHX
- PWM
1 stop7h 49m
American Airlines
Deal found 6/17![American Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:56 pm
PWM
- PHX
1 stop7h 41m
American Airlines
Wed 7/225:00 am
PHX
- PWM
1 stop9h 09m
American Airlines
Deal found 6/18![American Airlines logo]()
$468
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:00 am
PWM
- PHX
1 stop9h 03m
Delta
Fri 7/2411:40 am
PHX
- PWM
1 stop10h 19m
Delta
Deal found 6/17![Delta logo]()
$487
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:35 am
PWM
- PHX
2 stops10h 00m
Southwest
Thu 7/2310:55 am
PHX
- PWM
2 stops10h 15m
Southwest
Deal found 6/16![Southwest logo]()
$490
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Wed 7/2911:06 pm
PHX
- PWM
1 stop22h 10m
JetBlue
Deal found 6/18![JetBlue logo]()
$396
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:15 am
PWM
- PHX
2 stops11h 24m
United Airlines
Wed 7/2911:12 am
PHX
- PWM
1 stop7h 29m
United Airlines
Deal found 6/20![United Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 am
PWM
- PHX
2 stops10h 00m
Southwest
Wed 7/297:25 am
PHX
- PWM
2 stops8h 05m
Southwest
Deal found 6/20![Southwest logo]()
$476
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:15 am
PWM
- PHX
2 stops10h 11m
United Airlines
Mon 7/278:50 am
PHX
- PWM
1 stop7h 37m
United Airlines
Deal found 6/19![United Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 am
PWM
- PHX
2 stops9h 30m
Southwest
Mon 7/278:20 pm
PHX
- PWM
2 stops10h 35m
Southwest
Deal found 6/19![Southwest logo]()
$483
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This JetBlue deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:17 pm
PWM
- PHX
1 stop11h 26m
JetBlue
Deal found 6/16![JetBlue logo]()
$131
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Deal found 6/19![JetBlue logo]()
$146
This JetBlue deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:17 pm
PWM
- PHX
1 stop11h 26m
JetBlue
Deal found 6/16![JetBlue logo]()
$156
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:45 am
PWM
- PHX
1 stop9h 30m
Southwest
Deal found 6/17![Southwest logo]()
$189
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Deal found 6/18![JetBlue logo]()
$194
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
PWM
- PHX
1 stop9h 11m
American Airlines
Deal found 6/19![American Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:00 am
PWM
- PHX
2 stops32h 59m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:15 am
PWM
- PHX
2 stops10h 11m
United Airlines
Deal found 6/19![United Airlines logo]()
$207
This Sun Country Air deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:15 pm
PWM
- PHX
1 stop7h 23m
Sun Country Air
Deal found 6/18![Sun Country Air logo]()
$233
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:15 am
PWM
- PHX
2 stops11h 24m
United Airlines
Deal found 6/18![United Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:45 am
PWM
- PHX
2 stops8h 15m
Southwest
Deal found 6/20![Southwest logo]()
$235
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated June 21, 2026.
Round-trip from | $241 (JetBlue) |
|---|---|
One-way from | $131 (JetBlue) |
Popular in | June |
Cheapest in | January |
Average price | $583 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 8/19
8:00 am-12:59 pm
1 stop7h 59m
Phoenix Sky Harbor Intl
Sat 8/22
11:45 pm-11:38 am
1 stop8h 53m
$377
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 8/19
6:15 pm-10:20 pm
1 stop7h 05m
Phoenix Sky Harbor Intl
Wed 8/26
10:35 am-10:05 pm
2 stops8h 30m
$382
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 8/19
7:45 am-1:00 pm
2 stops8h 15m
Phoenix Sky Harbor Intl
Sat 8/22
11:10 pm-10:35 am
1 stop8h 25m
$390
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 8/4
5:45 am-5:05 pm
1 stop14h 20m
Phoenix Sky Harbor Intl
Tue 8/11
10:35 am-10:05 pm
2 stops8h 30m
$396
Quickest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 7/14
6:59 pm-11:59 pm
1 stop8h 00m
Phoenix Sky Harbor Intl
Mon 7/20
12:15 pm-10:36 pm
1 stop7h 21m
$432
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 7/23
5:15 am-12:26 pm
2 stops10h 11m
Phoenix Sky Harbor Intl
Mon 7/27
8:50 am-7:27 pm
1 stop7h 37m
$478
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 7/23
5:35 am-12:05 pm
2 stops9h 30m
Phoenix Sky Harbor Intl
Mon 7/27
8:20 pm-9:55 am
2 stops10h 35m
$483
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 7/14
5:30 am-12:40 pm
2 stops10h 10m
Phoenix Sky Harbor Intl
Mon 7/20
8:20 pm-9:55 am
2 stops10h 35m
$497
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 9/2
7:40 am-5:10 pm
2 stops12h 30m
Phoenix Sky Harbor Intl
Sat 9/5
11:28 am-9:23 pm
1 stop6h 55m
$500
Cheapest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 8/25
1:17 pm-9:43 pm
1 stop11h 26m
$131
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated June 21, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
7.9
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Overall
7.9
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Overall
7.9
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Overall
7.9
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Overall
7.9
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Portland
Popular flights
Top destinations
Alternative routes for Portland to Mesa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Mesa by cabin class
Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on June 21, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on June 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 4 airlines flying from Portland to Mesa
Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$456 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$477 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$263 | Average$423 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$482 | FlexibilityNo cancel fee | On-time63% |