$136+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
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Best
Last-minute
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Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:50 pm -
1 stop9h 57m
Fri 11/1312:20 am -
1 stop9h 33m
Deal found 9/14![American Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:03 pm -
1 stop9h 47m
Sat 11/148:00 am -
2 stops14h 19m
Deal found 9/14![Delta logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop8h 55m
Sat 11/2110:55 pm -
1 stop9h 43m
Deal found 9/14![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:03 pm -
1 stop9h 47m
Sat 11/2111:59 pm -
2 stops11h 02m
Deal found 9/14![Delta logo]()
$362
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:30 am -
1 stop8h 37m
Sat 10/311:21 pm -
1 stop7h 22m
Deal found 9/10![JetBlue logo]()
$373
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:30 am -
1 stop8h 37m
Tue 11/32:30 pm -
1 stop7h 13m
Deal found 9/10![JetBlue logo]()
$375
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:42 pm -
2 stops12h 03m
Sat 11/712:59 am -
1 stop7h 51m
Deal found 9/14![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop8h 55m
Sat 11/1412:20 am -
1 stop9h 15m
Deal found 9/14![American Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
1 stop10h 52m
Tue 11/37:34 am -
1 stop8h 43m
Deal found 9/10![American Airlines logo]()
$385
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:00 pm -
1 stop10h 04m
Thu 12/108:17 pm -
2 stops13h 40m
Deal found 9/10![Delta logo]()
$390
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:26 pm -
1 stop7h 33m
Sun 10/1811:15 pm -
1 stop8h 48m
Deal found 9/14![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:50 am -
2 stops11h 27m
Tue 12/157:00 am -
2 stops11h 42m
Deal found 9/10![United Airlines logo]()
$505
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:45 pm -
2 stops12h 10m
Fri 11/2012:59 am -
2 stops10h 09m
Deal found 9/13![Delta logo]()
$413
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:42 pm -
2 stops12h 39m
Tue 10/276:20 am -
1 stop6h 42m
Deal found 9/11![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop9h 50m
Mon 11/1611:30 am -
2 stops10h 49m
Deal found 9/12![Delta logo]()
$468
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated September 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:26 pm -
1 stop7h 33m
Sun 10/1811:15 pm -
1 stop8h 48m
Deal found 9/14![American Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:26 pm -
1 stop7h 33m
Sat 10/317:16 am -
1 stop6h 59m
Deal found 9/10![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:45 pm -
1 stop9h 59m
Mon 10/2612:36 am -
1 stop8h 55m
Deal found 9/11![American Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:42 pm -
2 stops12h 39m
Tue 10/276:20 am -
1 stop6h 42m
Deal found 9/11![Delta logo]()
$428
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:30 am -
1 stop8h 37m
Mon 11/22:30 pm -
1 stop7h 13m
Deal found 9/12![JetBlue logo]()
$447
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:30 am -
1 stop8h 37m
Sat 10/311:21 pm -
1 stop7h 22m
Deal found 9/10![JetBlue logo]()
$373
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:30 am -
1 stop8h 37m
Tue 11/32:30 pm -
1 stop7h 13m
Deal found 9/10![JetBlue logo]()
$375
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
1 stop10h 52m
Tue 11/37:34 am -
1 stop8h 43m
Deal found 9/10![American Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:05 pm -
1 stop9h 35m
Mon 11/212:30 am -
2 stops9h 40m
Deal found 9/10![Southwest logo]()
$390
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:03 am -
2 stops15h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$136
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:33 pm -
1 stop9h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$137
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:26 pm -
1 stop7h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$143
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:33 pm -
1 stop9h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$149
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:15 pm -
1 stop9h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$156
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:01 am -
1 stop9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$174
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:09 pm -
1 stop7h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:10 pm -
1 stop9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$182
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:08 pm -
1 stop8h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$186
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated September 15, 2026.
Round-trip from | $292 (American Airlines) |
|---|---|
One-way from | $136 (Delta) |
Popular in | June |
Cheapest in | January |
Average price | $480 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Sat 10/31
6:03 am-3:19 pm
2 stops12h 16m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$142
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Wed 12/16
3:25 pm-11:35 pm
2 stops10h 10m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$143
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Fri 10/30
4:47 pm-11:21 pm
2 stops9h 34m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$179
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Thu 12/17
5:10 pm-12:50 am
1 stop9h 40m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$182
Quickest round-trip
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Tue 11/3
5:08 pm-11:42 pm
1 stop8h 34m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$186
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Sat 11/14
6:00 am-4:40 pm
2 stops12h 40m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$198
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Tue 11/3
6:30 am-1:17 pm
1 stop8h 47m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$202
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Sat 10/31
6:30 am-12:07 pm
1 stop8h 37m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$202
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Sat 10/31
6:00 am-8:25 pm
3 stops17h 25m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$202
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Wed 11/11
6:00 am-7:45 pm
2 stops15h 45m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$207
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Airfare is below average for this route at the moment.
Portland, Maine to Mesa flights typically cost between $409 and $517 in November.The cheapest round-trip price found within the last 5 days was $292 on American Airlines (Nov 9-Nov 13).
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated September 15, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on September 15, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 5 airlines flying from Portland to Mesa
Discover the top 5 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$173 | Average$482 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$252 | Average$492 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$256 | Average$497 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$275 | Average$446 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$291 | Average$502 | FlexibilityNo cancel fee | On-time63% |