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Mesa

$181+ Cheap flights from Portland, ME (PWM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Jun 17 — Jun 241
Wed 6/17
Wed 6/24
1 adult, Economy
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Cheap flight deals from Portland to Mesa

Cheapest flights from Portland to Mesa
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.

This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:15 am
PWM
-
PHX
1 stop10h 17m
American Airlines
Tue 7/75:00 am
PHX
-
PWM
1 stop9h 10m
American Airlines
Deal found 5/13$361
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:24 pm
PWM
-
PHX
1 stop10h 36m
American Airlines
Mon 6/85:06 am
PHX
-
PWM
1 stop10h 19m
American Airlines
Deal found 5/15$371
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:36 pm
PWM
-
PHX
1 stop8h 57m
American Airlines
Tue 6/165:00 am
PHX
-
PWM
1 stop9h 06m
American Airlines
Deal found 5/13$374
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:58 am
PWM
-
PHX
1 stop7h 59m
American Airlines
Mon 6/85:00 am
PHX
-
PWM
1 stop9h 06m
American Airlines
Deal found 5/15$384
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:46 am
PWM
-
PHX
2 stops11h 22m
American Airlines
Thu 12/102:24 pm
PHX
-
PWM
1 stop7h 13m
American Airlines
Deal found 5/13$386
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:59 pm
PWM
-
PHX
1 stop8h 00m
American Airlines
Wed 7/225:00 am
PHX
-
PWM
1 stop9h 10m
American Airlines
Deal found 5/14$389
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:45 am
PWM
-
PHX
2 stops9h 45m
Southwest
Tue 8/1812:25 pm
PHX
-
PWM
1 stop6h 40m
Southwest
Deal found 5/14$395
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:45 am
PWM
-
PHX
2 stops9h 45m
Southwest
Tue 9/297:25 am
PHX
-
PWM
2 stops10h 45m
Southwest
Deal found 5/13$400
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:54 pm
PWM
-
PHX
1 stop8h 04m
American Airlines
Tue 6/235:00 am
PHX
-
PWM
1 stop9h 06m
American Airlines
Deal found 5/17$402
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:54 pm
PWM
-
PHX
1 stop8h 04m
American Airlines
Sat 6/205:00 am
PHX
-
PWM
1 stop9h 06m
American Airlines
Deal found 5/16$407

Find flight deals from Portland to Mesa

Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated May 18, 2026.

Round-trip from

$361
(American Airlines)

One-way from

$181
(United Airlines)

Popular in

May

Cheapest in

January

Average price

$507
From Portland to Mesa
Search Deals
One-way flight from Portland to Mesa
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Mon 10/5

6:30 am-12:40 pm

1 stop9h 10m

Phoenix Sky Harbor Intl

Mon 10/12

5:10 pm-9:45 am

1 stop13h 35m

$424

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Fri 6/5

5:20 pm-12:10 am

2 stops9h 50m

Phoenix Sky Harbor Intl

Sun 6/7

11:55 pm-12:20 pm

2 stops9h 25m

$469

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Thu 7/2

5:20 pm-12:10 am

2 stops9h 50m

Phoenix Sky Harbor Intl

Sun 7/5

2:40 pm-9:45 am

2 stops16h 05m

$475

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 9/26

6:00 am-12:33 pm

1 stop9h 33m

Phoenix Sky Harbor Intl

Mon 10/5

6:41 pm-9:23 am

2 stops11h 42m

$476

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 6/6

12:35 pm-8:45 pm

2 stops11h 10m

Phoenix Sky Harbor Intl

Mon 6/8

10:25 pm-9:55 am

1 stop8h 30m

$481
Quickest round-trip

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Tue 8/11

7:45 am-1:00 pm

2 stops8h 15m

Phoenix Sky Harbor Intl

Fri 8/21

10:05 am-10:25 pm

2 stops9h 20m

$489

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Tue 6/16

3:45 pm-10:50 pm

2 stops10h 05m

Phoenix Sky Harbor Intl

Fri 6/19

11:35 am-12:05 am

2 stops9h 30m

$514

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Fri 6/5

2:37 pm-10:53 pm

1 stop11h 16m

Phoenix Sky Harbor Intl

Mon 6/8

11:58 pm-1:35 pm

1 stop10h 37m

$528

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Tue 6/9

6:00 am-5:40 pm

2 stops14h 40m

Phoenix Sky Harbor Intl

Tue 6/16

6:50 am-11:51 pm

2 stops14h 01m

$533

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Mon 6/8

5:00 pm-11:37 pm

1 stop9h 37m

Phoenix Sky Harbor Intl

Tue 6/16

6:50 am-11:51 pm

2 stops14h 01m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/16

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Portland to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Mesa

How much does it cost to fly round-trip from Portland, Maine to Mesa?

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated May 18, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,287 reviews

Entertainment

7.5

Overall

7.9

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,287 reviews
Southwest
7.9
Good
4,287 reviews

Entertainment

7.5

Overall

7.9

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,447 reviews
Southwest
7.9
Good
4,287 reviews

Entertainment

7.5

Overall

7.9

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,737 reviews
Southwest
7.9
Good
4,287 reviews

Entertainment

7.5

Overall

7.9

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,648 reviews
Southwest
7.9
Good
4,287 reviews

Entertainment

7.5

Overall

7.9

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Mesa?

    Located just 2.9 mi from the city center, Portland is the airport most travelers will use when flying to Mesa from Portland. Booking flights from Portland (PWM) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 4 different airlines.

  • How long is the flight from Portland, Maine to Mesa?

    There are many flights that can get you from Portland, Maine to Mesa in 9h 10m. Fly via Southwest or United Airlines to get the fastest option. The distance between Portland, Maine and Mesa is about 2332 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $108. Users have also found prices from $116 and $125 on Southwest and United Airlines, respectively.

  • Can I find deals for flights from Portland to Mesa that include hotel bookings?

    Yes. In addition to deals on Portland to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Mesa.

  • Can I find deals for business class flights from Portland to Mesa?

    Yes. Cheapflights offers flight deals from Portland to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Portland to Mesa

Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$230Average$417FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$252Average$468FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$409FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$276Average$478FlexibilityNo cancel feeOn-time63%

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