What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?

For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $126. Users have also found prices from $136 and $150 on United Airlines and Delta, respectively.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Portland, Maine to Mesa?

The most popular airlines flying from Portland, Maine to Mesa are American Airlines, United Airlines and Southwest. Something to consider prior to booking your flight.

What is the cheapest time of day to fly from PWM to MS9?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Portland, Maine to Mesa as you normally would.

What airport do you fly from for flights from Portland to Mesa?

Located just 2.9 mi from the city center, Portland is the airport most travelers will use when flying to Mesa from Portland. Booking flights from Portland (PWM) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 5 different airlines.

Can I find deals for flights from Portland to Mesa that include hotel bookings?

Yes. In addition to deals on Portland to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to Mesa?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Mesa.

Can I find deals for business class flights from Portland to Mesa?

Yes. Cheapflights offers flight deals from Portland to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Portland, ME to Mesa

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Find flight deals from Portland to Mesa

Popular in	June
Cheapest in	February
Average price	$432

Highest demand for flights based on searches. 14% potential increase in price ($80 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Reviews of airlines servicing Mesa

See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,219 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Southwest

7.9

Good

4,219 reviews

Southwest

7.9

Good

4,219 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Delta

7.8

Good

8,659 reviews

Southwest

7.9

Good

4,219 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

United Airlines

7.4

Good

10,370 reviews

Southwest

7.9

Good

4,219 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

JetBlue

7.1

Good

3,057 reviews

Southwest

7.9

Good

4,219 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

American Airlines

7.0

Good

12,169 reviews

Southwest

7.9

Good

4,219 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

What airport do you fly from for flights from Portland to Mesa?
Located just 2.9 mi from the city center, Portland is the airport most travelers will use when flying to Mesa from Portland. Booking flights from Portland (PWM) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 5 different airlines.
What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?
For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $126. Users have also found prices from $136 and $150 on United Airlines and Delta, respectively.
Can I find deals for flights from Portland to Mesa that include hotel bookings?
Yes. In addition to deals on Portland to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to Mesa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Mesa.
Can I find deals for business class flights from Portland to Mesa?
Yes. Cheapflights offers flight deals from Portland to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 5 airlines flying from Portland to Mesa

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$173	Average$482	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$217	Average$466	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$252	Average$494	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$275	Average$449	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$292	Average$517	FlexibilityNo cancel fee	On-time63%

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Find cheap flights from Portland to Mesa with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Portland to Mesa

Popular in

Cheapest in

Average price

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated October 16, 2026.

See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Portland to Mesa?

What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?

Can I find deals for flights from Portland to Mesa that include hotel bookings?

How can I find direct flights from Portland to Mesa?

Can I find deals for business class flights from Portland to Mesa?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Portland to Mesa by cabin class

Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Portland and Mesa flights

Browse other Portland and Mesa flight options. Last updated on October 16, 2026.

Other flights from Portland

Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on October 16, 2026.

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Portland to Mesa flights

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Cheap flights from Portland, ME (PWM) to Mesa, AZ

Find cheap flights from Portland to Mesa with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Portland to Mesa

Popular in

Cheapest in

Average price

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated October 16, 2026.

See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Portland to Mesa?

What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?

Can I find deals for flights from Portland to Mesa that include hotel bookings?

How can I find direct flights from Portland to Mesa?

Can I find deals for business class flights from Portland to Mesa?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Portland to Mesa by cabin class

Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Portland and Mesa flights

Browse other Portland and Mesa flight options. Last updated on October 16, 2026.

Other flights from Portland

Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on October 16, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Portland to Mesa flights

Consider these flights traveling from Portland to Mesa.

Top 5 airlines flying from Portland to Mesa

100% Free

Book with Flexibility

Travel Smart