$165+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
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Best
Last-minute
One-way
Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This JetBlue deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
PWM
- PHX
1 stop9h 34m
JetBlue
Tue 10/201:20 pm
PHX
- PWM
1 stop7h 32m
JetBlue
Deal found 7/27![JetBlue logo]()
$329
This Justfly.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Wed 9/161:32 pm
PHX
- PWM
1 stop7h 22m
JetBlue
Deal found 7/29![JetBlue logo]()
$331
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:09 pm
PWM
- PHX
1 stop10h 36m
Delta
Tue 11/107:00 am
PHX
- PWM
1 stop6h 58m
Delta
Deal found 7/29![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:45 am
PWM
- PHX
1 stop9h 30m
Southwest
Tue 9/18:20 am
PHX
- PWM
2 stops9h 50m
Southwest
Deal found 7/28![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:45 pm
PWM
- PHX
1 stop9h 49m
American Airlines
Tue 10/2012:31 am
PHX
- PWM
1 stop8h 40m
American Airlines
Deal found 7/26![American Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:48 pm
PWM
- PHX
1 stop11h 12m
American Airlines
Tue 11/1011:25 am
PHX
- PWM
2 stops9h 08m
American Airlines
Deal found 7/26![American Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:25 pm
PWM
- PHX
2 stops9h 35m
Southwest
Sun 11/11:35 am
PHX
- PWM
2 stops9h 30m
Southwest
Deal found 7/25![Southwest logo]()
$348
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:03 am
PWM
- PHX
1 stop8h 05m
United Airlines
Thu 8/2711:32 am
PHX
- PWM
2 stops9h 27m
United Airlines
Deal found 7/28![United Airlines logo]()
$356
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This JetBlue deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Wed 9/161:32 pm
PHX
- PWM
1 stop7h 22m
JetBlue
Deal found 7/26![JetBlue logo]()
$329
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:50 pm
PWM
- PHX
1 stop8h 39m
Delta
Thu 12/107:00 am
PHX
- PWM
1 stop6h 58m
Delta
Deal found 7/27![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:30 pm
PWM
- PHX
2 stops8h 55m
Southwest
Thu 10/2211:00 am
PHX
- PWM
2 stops7h 50m
Southwest
Deal found 7/25![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:40 am
PWM
- PHX
1 stop10h 40m
United Airlines
Sat 8/296:00 am
PHX
- PWM
1 stop6h 51m
United Airlines
Deal found 7/28![United Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:15 pm
PWM
- PHX
1 stop9h 58m
Delta
Tue 11/1010:40 am
PHX
- PWM
2 stops10h 53m
Delta
Deal found 7/28![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:25 am
PWM
- PHX
1 stop9h 15m
Southwest
Thu 10/2912:15 pm
PHX
- PWM
2 stops8h 40m
Southwest
Deal found 7/27![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:50 pm
PWM
- PHX
1 stop8h 32m
Delta
Sun 11/1511:59 pm
PHX
- PWM
1 stop7h 31m
Delta
Deal found 7/24![Delta logo]()
$418
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:40 am
PWM
- PHX
2 stops9h 55m
Southwest
Fri 10/212:15 pm
PHX
- PWM
1 stop6h 35m
Southwest
Deal found 7/25![Southwest logo]()
$438
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated July 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:09 pm
PWM
- PHX
1 stop9h 05m
American Airlines
Sat 8/2211:45 pm
PHX
- PWM
1 stop8h 53m
American Airlines
Deal found 7/27![American Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:03 am
PWM
- PHX
1 stop8h 05m
United Airlines
Thu 8/2711:32 am
PHX
- PWM
2 stops9h 27m
United Airlines
Deal found 7/28![United Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:03 am
PWM
- PHX
1 stop8h 05m
United Airlines
Fri 8/286:19 am
PHX
- PWM
1 stop8h 23m
United Airlines
Deal found 7/29![United Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:53 pm
PWM
- PHX
1 stop8h 41m
Delta
Tue 9/16:00 am
PHX
- PWM
1 stop7h 01m
Delta
Deal found 7/26![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:45 am
PWM
- PHX
1 stop9h 30m
Southwest
Tue 9/18:20 am
PHX
- PWM
2 stops9h 50m
Southwest
Deal found 7/28![Southwest logo]()
$338
This JetBlue deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Sat 8/2911:06 pm
PHX
- PWM
1 stop10h 24m
JetBlue
Deal found 7/26![JetBlue logo]()
$373
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:28 am
PWM
- PHX
1 stop8h 41m
American Airlines
Sun 8/305:05 am
PHX
- PWM
1 stop9h 27m
American Airlines
Deal found 7/25![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:45 am
PWM
- PHX
1 stop9h 30m
Southwest
Sun 8/309:50 am
PHX
- PWM
2 stops10h 05m
Southwest
Deal found 7/25![Southwest logo]()
$413
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This JetBlue deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
PWM
- PHX
1 stop9h 39m
JetBlue
Deal found 7/27![JetBlue logo]()
$165
This JetBlue deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Deal found 7/29![JetBlue logo]()
$166
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am
PWM
- PHX
1 stop8h 08m
United Airlines
Deal found 7/26![United Airlines logo]()
$167
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:53 pm
PWM
- PHX
2 stops11h 48m
Delta
Deal found 7/29![Delta logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
PWM
- PHX
3 stops55h 42m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$197
This JetBlue deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
PWM
- PHX
1 stop9h 25m
JetBlue
Deal found 7/29![JetBlue logo]()
$199
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:20 pm
PWM
- PHX
1 stop9h 44m
Delta
Deal found 7/28![Delta logo]()
$200
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:55 pm
PWM
- PHX
2 stops11h 31m
Delta
Deal found 7/29![Delta logo]()
$205
This JetBlue deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
PWM
- PHX
1 stop9h 31m
JetBlue
Deal found 7/27![JetBlue logo]()
$209
This JetBlue deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am
PWM
- PHX
1 stop9h 25m
JetBlue
Deal found 7/29![JetBlue logo]()
$210
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:17 pm
PWM
- PHX
1 stop11h 26m
JetBlue
Deal found 7/28![JetBlue logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am
PWM
- PHX
3 stops20h 43m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$216
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated July 29, 2026.
Round-trip from | $329 (JetBlue) |
|---|---|
One-way from | $165 (JetBlue) |
Popular in | June |
Cheapest in | January |
Average price | $558 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 9/2
2:40 pm-9:43 pm
1 stop10h 03m
Phoenix Sky Harbor Intl
Wed 9/16
1:32 pm-11:54 pm
1 stop7h 22m
$329
Quickest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Mon 12/7
12:50 pm-7:29 pm
1 stop8h 39m
Phoenix Sky Harbor Intl
Thu 12/10
7:00 am-3:58 pm
1 stop6h 58m
$333
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Mon 11/2
4:15 pm-12:13 am
1 stop9h 58m
Phoenix Sky Harbor Intl
Tue 11/10
10:40 am-11:33 pm
2 stops10h 53m
$338
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 10/15
5:30 pm-11:25 pm
2 stops8h 55m
Phoenix Sky Harbor Intl
Thu 10/22
11:00 am-9:50 pm
2 stops7h 50m
$393
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Sun 10/25
7:25 am-1:40 pm
1 stop9h 15m
Phoenix Sky Harbor Intl
Thu 10/29
12:15 pm-11:55 pm
2 stops8h 40m
$413
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 11/11
4:50 pm-11:22 pm
1 stop8h 32m
Phoenix Sky Harbor Intl
Sun 11/15
11:59 pm-9:30 am
1 stop7h 31m
$418
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 9/25
7:40 am-2:35 pm
2 stops9h 55m
Phoenix Sky Harbor Intl
Fri 10/2
12:15 pm-9:50 pm
1 stop6h 35m
$438
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 8/26
7:40 am-3:20 pm
1 stop10h 40m
Phoenix Sky Harbor Intl
Sat 8/29
6:00 am-3:51 pm
1 stop6h 51m
$443
Cheapest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 9/10
6:00 am-12:39 pm
1 stop9h 39m
$165
Quickest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 8/25
6:00 am-11:08 am
1 stop8h 08m
$167
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Airfare is typical for this route at the moment.
Portland, Maine to Mesa flights typically cost between $301 and $533 in October.The cheapest round-trip price found within the last 5 days was $329 on JetBlue (Oct 6-Oct 20).
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated July 29, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentSherrie,Jan 2024
LAX - PHX
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Portland to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Mesa by cabin class
Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on July 29, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 5 airlines flying from Portland to Mesa
Discover the top 5 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$456 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$481 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$266 | Average$437 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$289 | Average$514 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$291 | Average$488 | FlexibilityNo cancel fee | On-time63% |