$179+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Sep 28 — Oct 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Portland to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:45 pm -
1 stop7h 53m
Tue 10/2711:15 pm -
1 stop9h 20m
Deal found 8/27![American Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:32 am -
1 stop10h 33m
Tue 9/296:30 am -
1 stop10h 08m
Deal found 8/26![American Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:15 am -
1 stop8h 27m
Tue 10/2711:20 am -
2 stops9h 01m
Deal found 8/27![United Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:27 pm -
1 stop9h 56m
Wed 12/212:20 am -
1 stop9h 33m
Deal found 8/25![American Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
2 stops13h 23m
Thu 12/108:17 pm -
2 stops13h 40m
Deal found 8/27![Delta logo]()
$368
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:13 pm -
2 stops9h 54m
Sat 11/711:27 am -
2 stops9h 30m
Deal found 8/27![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:27 pm -
1 stop9h 56m
Wed 12/211:27 am -
2 stops9h 06m
Deal found 8/25![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:05 am -
1 stop8h 48m
Tue 10/61:16 pm -
1 stop7h 43m
Deal found 8/27![American Airlines logo]()
$371
This deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:55 pm -
1 stop8h 08m
Tue 9/2911:37 am -
1 stop9h 19m
Deal found 8/26![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 am -
2 stops12h 56m
Tue 10/61:30 pm -
1 stop7h 05m
Deal found 8/27![Delta logo]()
$376
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 58m
Mon 11/3012:59 am -
2 stops8h 58m
Deal found 8/27![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:08 pm -
1 stop8h 54m
Sat 11/2111:30 pm -
1 stop7h 30m
Deal found 8/27![United Airlines logo]()
$380
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:06 pm -
1 stop8h 31m
Tue 1/1212:50 pm -
1 stop6h 37m
Deal found 8/24![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/512:50 pm -
2 stops13h 16m
Tue 1/121:00 pm -
1 stop8h 49m
Deal found 8/27![Delta logo]()
$362
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:15 am -
2 stops10h 30m
Tue 1/1211:30 am -
2 stops8h 10m
Deal found 8/27![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:53 pm -
2 stops9h 54m
Thu 12/107:02 am -
1 stop7h 09m
Deal found 8/26![Delta logo]()
$362
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:35 am -
2 stops11h 30m
Sun 1/101:30 am -
2 stops8h 40m
Deal found 8/27![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1112:50 pm -
2 stops13h 16m
Fri 1/1512:55 am -
2 stops8h 58m
Deal found 8/26![Delta logo]()
$368
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/218:50 am -
1 stop10h 30m
Thu 2/2511:40 pm -
1 stop6h 30m
Deal found 8/25![Southwest logo]()
$420
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop9h 50m
Sun 11/1511:35 pm -
2 stops11h 26m
Deal found 8/27![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 pm -
2 stops10h 15m
Tue 11/311:40 pm -
1 stop8h 10m
Deal found 8/28![Southwest logo]()
$429
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated August 29, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated August 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:05 am -
1 stop8h 48m
Tue 10/61:16 pm -
1 stop7h 43m
Deal found 8/27![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 am -
2 stops12h 56m
Tue 10/61:30 pm -
1 stop7h 05m
Deal found 8/27![Delta logo]()
$376
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am -
1 stop7h 59m
Sun 9/65:05 am -
1 stop8h 59m
Deal found 8/28![American Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
2 stops12h 55m
Sun 9/611:29 am -
1 stop10h 30m
Deal found 8/28![Delta logo]()
$390
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am -
1 stop9h 10m
Wed 9/306:30 am -
1 stop10h 08m
Deal found 8/28![American Airlines logo]()
$395
This deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:55 pm -
1 stop8h 08m
Tue 9/2911:37 am -
1 stop9h 19m
Deal found 8/26![Delta logo]()
$374
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:32 am -
1 stop10h 33m
Tue 9/296:30 am -
1 stop10h 08m
Deal found 8/27![American Airlines logo]()
$357
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:35 am -
1 stop9h 00m
Deal found 8/27![United Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:04 am -
2 stops12h 15m
Deal found 8/27![Delta logo]()
$184
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:14 pm -
1 stop9h 42m
Deal found 8/26![Delta logo]()
$193
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:00 am -
1 stop9h 10m
Deal found 8/25![American Airlines logo]()
$196
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:08 pm -
1 stop8h 16m
Deal found 8/29![United Airlines logo]()
$202
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:39 am -
2 stops12h 32m
Deal found 8/28![Delta logo]()
$207
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:38 pm -
1 stop9h 44m
Deal found 8/28![American Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:09 pm -
3 stops27h 17m
Deal found 8/27![Multiple Airlines logo]()
$226
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:55 pm -
2 stops13h 43m
Deal found 8/28![Delta logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:00 am -
3 stops31h 59m
Deal found 8/25![Multiple Airlines logo]()
$232
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/54:48 pm -
1 stop7h 56m
Deal found 8/27![United Airlines logo]()
$234
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated August 29, 2026.
Round-trip from | $357 (American Airlines) |
|---|---|
One-way from | $179 (United Airlines) |
Popular in | June |
Cheapest in | January |
Average price | $511 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Tue 1/5
5:06 pm-11:37 pm
1 stop8h 31m
Phoenix Sky Harbor Intl
Tue 1/12
12:50 pm-9:27 pm
1 stop6h 37m
$357
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Tue 1/5
12:50 pm-12:06 am
2 stops13h 16m
Phoenix Sky Harbor Intl
Tue 1/12
1:00 pm-11:49 pm
1 stop8h 49m
$362
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Mon 12/7
4:53 pm-12:47 am
2 stops9h 54m
Phoenix Sky Harbor Intl
Thu 12/10
7:02 am-4:11 pm
1 stop7h 09m
$362
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Tue 1/5
5:15 am-1:45 pm
2 stops10h 30m
Phoenix Sky Harbor Intl
Tue 1/12
11:30 am-9:40 pm
2 stops8h 10m
$367
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Wed 1/6
5:35 am-3:05 pm
2 stops11h 30m
Phoenix Sky Harbor Intl
Sun 1/10
1:30 am-12:10 pm
2 stops8h 40m
$367
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Mon 1/11
12:50 pm-12:06 am
2 stops13h 16m
Phoenix Sky Harbor Intl
Fri 1/15
12:55 am-11:53 am
2 stops8h 58m
$368
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Sun 2/21
8:50 am-5:20 pm
1 stop10h 30m
Phoenix Sky Harbor Intl
Thu 2/25
11:40 pm-8:10 am
1 stop6h 30m
$420
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Wed 11/11
6:00 am-1:50 pm
1 stop9h 50m
Phoenix Sky Harbor Intl
Sun 11/15
11:35 pm-1:01 pm
2 stops11h 26m
$425
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Thu 10/29
5:30 pm-12:45 am
2 stops10h 15m
Phoenix Sky Harbor Intl
Tue 11/3
11:40 pm-9:50 am
1 stop8h 10m
$429
Cheapest one-way
PortlandPhoenix
PWM Portland - PHX Phoenix Sky Harbor Intl
PWMPHX
Portland
Sat 10/24
11:35 am-5:35 pm
1 stop9h 00m
$179
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
PWM-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
PWM-MS9
PWM-PHX
How much does it cost to fly round-trip from Portland, Maine to Mesa?
Airfare is below average for this route at the moment.
Portland, Maine to Mesa flights typically cost between $361 and $496 in October.The cheapest round-trip price found within the last 5 days was $357 on American Airlines (Oct 20-Oct 27).
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated August 29, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Portland
Popular flights
Top destinations
Alternative routes for Portland to Mesa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Mesa by cabin class
Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on August 29, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on August 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 5 airlines flying from Portland to Mesa
Discover the top 5 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$173 | Average$482 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$230 | Average$481 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$483 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$273 | Average$443 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$291 | Average$498 | FlexibilityNo cancel fee | On-time63% |