$146+ Cheap flights from Portland, ME (PWM) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Jul 23 — Jul 301
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Mesa with Cheapflights
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Cheapest flights from Portland to MesaExplore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Sat 9/511:06 pm
PHX
- PWM
1 stop10h 15m
JetBlue
Deal found 6/18![JetBlue logo]()
$241
This flygcity.se deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:49 pm
PWM
- PHX
1 stop9h 54m
JetBlue
Sun 8/1611:06 pm
PHX
- PWM
1 stop10h 15m
JetBlue
Deal found 6/18![JetBlue logo]()
$247
This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:25 pm
PWM
- PHX
1 stop11h 20m
JetBlue
Mon 7/2711:06 pm
PHX
- PWM
1 stop10h 24m
JetBlue
Deal found 6/22![JetBlue logo]()
$314
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:40 pm
PWM
- PHX
1 stop10h 03m
JetBlue
Sat 8/2911:06 pm
PHX
- PWM
1 stop10h 15m
JetBlue
Deal found 6/19![JetBlue logo]()
$355
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:47 pm
PWM
- PHX
1 stop7h 45m
Delta
Tue 8/1110:19 am
PHX
- PWM
1 stop9h 54m
Delta
Deal found 6/22![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:05 pm
PWM
- PHX
2 stops9h 15m
Southwest
Sat 10/310:30 pm
PHX
- PWM
1 stop8h 15m
Southwest
Deal found 6/23![Southwest logo]()
$382
This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
PWM
- PHX
1 stop9h 25m
JetBlue
Sat 10/31:20 pm
PHX
- PWM
1 stop7h 32m
JetBlue
Deal found 6/22![JetBlue logo]()
$387
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:45 am
PWM
- PHX
2 stops8h 15m
Southwest
Sat 8/2211:10 pm
PHX
- PWM
1 stop8h 25m
Southwest
Deal found 6/20![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:50 pm
PWM
- PHX
1 stop8h 32m
Delta
Tue 11/2411:59 pm
PHX
- PWM
1 stop7h 31m
Delta
Deal found 6/22![Delta logo]()
$393
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:40 pm
PWM
- PHX
2 stops9h 15m
Southwest
Sat 8/299:45 am
PHX
- PWM
1 stop8h 15m
Southwest
Deal found 6/19![Southwest logo]()
$395
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Wed 7/2911:06 pm
PHX
- PWM
1 stop22h 10m
JetBlue
Deal found 6/18![JetBlue logo]()
$396
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 am
PWM
- PHX
1 stop10h 39m
American Airlines
Thu 8/205:05 am
PHX
- PWM
1 stop10h 01m
American Airlines
Deal found 6/21![American Airlines logo]()
$399
Best flights from Portland to MesaDiscover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from Portland to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:47 pm
PWM
- PHX
1 stop7h 45m
Delta
Tue 8/1110:19 am
PHX
- PWM
1 stop9h 54m
Delta
Deal found 6/22![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:45 am
PWM
- PHX
1 stop14h 20m
Southwest
Tue 8/1110:35 am
PHX
- PWM
2 stops8h 30m
Southwest
Deal found 6/22![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:40 am
PWM
- PHX
2 stops12h 30m
United Airlines
Sat 9/511:28 am
PHX
- PWM
1 stop6h 55m
United Airlines
Deal found 6/18![United Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:56 pm
PWM
- PHX
1 stop7h 41m
American Airlines
Fri 7/1012:36 pm
PHX
- PWM
1 stop8h 23m
American Airlines
Deal found 6/23![American Airlines logo]()
$523
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 am
PWM
- PHX
2 stops9h 30m
Southwest
Mon 7/278:20 pm
PHX
- PWM
2 stops10h 35m
Southwest
Deal found 6/19![Southwest logo]()
$483
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:55 am
PWM
- PHX
2 stops9h 00m
Southwest
Sun 8/1611:10 pm
PHX
- PWM
1 stop7h 40m
Southwest
Deal found 6/18![Southwest logo]()
$495
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:59 pm
PWM
- PHX
1 stop8h 00m
American Airlines
Sat 7/1110:15 am
PHX
- PWM
1 stop10h 19m
American Airlines
Deal found 6/22![American Airlines logo]()
$583
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:40 am
PWM
- PHX
1 stop8h 15m
Southwest
Thu 7/2310:55 am
PHX
- PWM
2 stops10h 15m
Southwest
Deal found 6/18![Southwest logo]()
$528
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:30 am
PWM
- PHX
1 stop14h 25m
Southwest
Fri 7/2410:55 am
PHX
- PWM
2 stops10h 15m
Southwest
Deal found 6/18![Southwest logo]()
$551
Last-minute flights from Portland to MesaDiscover last-minute flight deals from Portland to Mesa. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Mesa. Data last updated June 23, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:30 pm
PWM
- PHX
1 stop10h 16m
JetBlue
Sat 7/1111:06 pm
PHX
- PWM
1 stop10h 24m
JetBlue
Deal found 6/22![JetBlue logo]()
$424
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:24 pm
PWM
- PHX
1 stop7h 50m
American Airlines
Tue 7/2112:15 pm
PHX
- PWM
1 stop7h 21m
American Airlines
Deal found 6/18![American Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
PWM
- PHX
1 stop7h 30m
Delta
Fri 7/2411:40 am
PHX
- PWM
1 stop10h 19m
Delta
Deal found 6/18![Delta logo]()
$432
This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:25 pm
PWM
- PHX
1 stop11h 20m
JetBlue
Mon 7/2711:06 pm
PHX
- PWM
1 stop10h 24m
JetBlue
Deal found 6/22![JetBlue logo]()
$314
This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:25 pm
PWM
- PHX
1 stop11h 20m
JetBlue
Sat 7/2511:06 pm
PHX
- PWM
1 stop10h 24m
JetBlue
Deal found 6/22![JetBlue logo]()
$387
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
PWM
- PHX
2 stops21h 06m
Delta
Sat 7/2512:15 pm
PHX
- PWM
1 stop9h 44m
Delta
Deal found 6/22![Delta logo]()
$441
This JetBlue deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Wed 7/2911:06 pm
PHX
- PWM
1 stop22h 10m
JetBlue
Deal found 6/18![JetBlue logo]()
$396
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
PWM
- PHX
1 stop17h 08m
Delta
Mon 7/2711:49 pm
PHX
- PWM
2 stops20h 41m
Delta
Deal found 6/22![Delta logo]()
$428
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:15 am
PWM
- PHX
2 stops11h 24m
United Airlines
Wed 7/2911:12 am
PHX
- PWM
1 stop7h 29m
United Airlines
Deal found 6/20![United Airlines logo]()
$430
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
PWM
- PHX
1 stop17h 08m
Delta
Sun 7/2610:35 pm
PHX
- PWM
1 stop23h 24m
Delta
Deal found 6/22![Delta logo]()
$431
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2311:47 am
PWM
- PHX
1 stop7h 22m
Delta
Fri 7/2410:35 pm
PHX
- PWM
1 stop23h 24m
Delta
Deal found 6/22![Delta logo]()
$444
One-way flights from Portland to MesaSearch for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from Portland to Mesa. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Deal found 6/19![JetBlue logo]()
$146
This JetBlue deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:25 pm
PWM
- PHX
1 stop11h 18m
JetBlue
Deal found 6/23![JetBlue logo]()
$151
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:24 pm
PWM
- PHX
1 stop7h 50m
American Airlines
Deal found 6/18![American Airlines logo]()
$189
This JetBlue deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:40 pm
PWM
- PHX
1 stop10h 05m
JetBlue
Deal found 6/22![JetBlue logo]()
$194
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
PWM
- PHX
1 stop9h 11m
American Airlines
Deal found 6/19![American Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:00 am
PWM
- PHX
2 stops32h 59m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:15 am
PWM
- PHX
2 stops10h 11m
United Airlines
Deal found 6/19![United Airlines logo]()
$207
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:30 am
PWM
- PHX
2 stops10h 10m
Southwest
Deal found 6/21![Southwest logo]()
$225
This Sun Country Air deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:15 pm
PWM
- PHX
1 stop7h 23m
Sun Country Air
Deal found 6/18![Sun Country Air logo]()
$233
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:15 am
PWM
- PHX
2 stops11h 24m
United Airlines
Deal found 6/18![United Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:45 am
PWM
- PHX
2 stops8h 15m
Southwest
Deal found 6/20![Southwest logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
PWM
- PHX
3 stops31h 26m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$237
Find flight deals from Portland to Mesa
Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated June 23, 2026.
Round-trip from | $241 (JetBlue) |
|---|---|
One-way from | $146 (Priceline) |
Popular in | June |
Cheapest in | January |
Average price | $583 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 8/4
4:47 pm-9:32 pm
1 stop7h 45m
Phoenix Sky Harbor Intl
Tue 8/11
10:19 am-11:13 pm
1 stop9h 54m
$377
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 8/4
5:45 am-5:05 pm
1 stop14h 20m
Phoenix Sky Harbor Intl
Tue 8/11
10:35 am-10:05 pm
2 stops8h 30m
$396
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 7/23
5:35 am-12:05 pm
2 stops9h 30m
Phoenix Sky Harbor Intl
Mon 7/27
8:20 pm-9:55 am
2 stops10h 35m
$483
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 8/7
5:55 am-11:55 am
2 stops9h 00m
Phoenix Sky Harbor Intl
Sun 8/16
11:10 pm-9:50 am
1 stop7h 40m
$495
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 9/2
7:40 am-5:10 pm
2 stops12h 30m
Phoenix Sky Harbor Intl
Sat 9/5
11:28 am-9:23 pm
1 stop6h 55m
$500
Quickest round-trip
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 7/3
2:56 pm-7:37 pm
1 stop7h 41m
Phoenix Sky Harbor Intl
Fri 7/10
12:36 pm-11:59 pm
1 stop8h 23m
$523
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Thu 7/16
7:40 am-12:55 pm
1 stop8h 15m
Phoenix Sky Harbor Intl
Thu 7/23
10:55 am-12:10 am
2 stops10h 15m
$528
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Wed 7/15
5:30 am-4:55 pm
1 stop14h 25m
Phoenix Sky Harbor Intl
Fri 7/24
10:55 am-12:10 am
2 stops10h 15m
$551
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Fri 7/10
6:59 pm-11:59 pm
1 stop8h 00m
Phoenix Sky Harbor Intl
Sat 7/11
10:15 am-11:34 pm
1 stop10h 19m
$583
Cheapest one-way
PortlandPhoenix
PWM - PHX
PWMPHX
Portland
Tue 8/25
1:25 pm-9:43 pm
1 stop11h 18m
$151
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Portland to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Mesa
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How much does it cost to fly round-trip from Portland, Maine to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated June 23, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Mesa by cabin class
Find flights from Portland to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Mesa flights
Browse other Portland and Mesa flight options. Last updated on June 23, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Mesa flights
Consider these flights traveling from Portland to Mesa.
Top 4 airlines flying from Portland to Mesa
Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$456 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$474 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$263 | Average$424 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$482 | FlexibilityNo cancel fee | On-time63% |