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Mesa

$126+ Cheap flights from Portland, ME (PWM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — PHX
Feb 22 — Mar 11
Sun 2/22
Sun 3/1
1 adult, Economy
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Cheap flight deals from Portland to Mesa

Cheapest flights from Portland to Mesa
Explore the most affordable flight options available from Portland to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 23, 2026.

This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:57 pm
PWM
-
PHX
1 stop8h 07m
American Airlines
Sat 2/286:05 am
PHX
-
PWM
1 stop9h 22m
American Airlines
Deal found 1/22$251
This Southwest deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/231:00 pm
PWM
-
PHX
1 stop11h 10m
Southwest
Wed 2/2511:40 pm
PHX
-
PWM
1 stop9h 35m
Southwest
Deal found 1/22$276
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:40 pm
PWM
-
PHX
1 stop8h 24m
American Airlines
Tue 2/2412:51 am
PHX
-
PWM
2 stops9h 08m
American Airlines
Deal found 1/22$281
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:40 pm
PWM
-
PHX
1 stop8h 24m
American Airlines
Mon 2/231:01 am
PHX
-
PWM
1 stop7h 24m
American Airlines
Deal found 1/22$288
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:13 pm
PWM
-
PHX
2 stops13h 16m
Delta
Tue 3/311:59 pm
PHX
-
PWM
2 stops9h 19m
Delta
Deal found 1/21$290
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:40 pm
PWM
-
PHX
1 stop8h 10m
American Airlines
Fri 5/111:32 pm
PHX
-
PWM
1 stop7h 51m
American Airlines
Deal found 1/22$301
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:57 pm
PWM
-
PHX
1 stop8h 07m
American Airlines
Sat 3/145:05 am
PHX
-
PWM
1 stop9h 22m
American Airlines
Deal found 1/21$305
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/234:48 pm
PWM
-
PHX
1 stop8h 06m
Delta
Mon 3/3011:59 pm
PHX
-
PWM
2 stops13h 07m
Delta
Deal found 1/21$306
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:57 pm
PWM
-
PHX
1 stop8h 07m
American Airlines
Wed 3/412:51 am
PHX
-
PWM
2 stops9h 08m
American Airlines
Deal found 1/22$307
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:29 pm
PWM
-
PHX
1 stop8h 51m
American Airlines
Mon 3/26:05 am
PHX
-
PWM
1 stop9h 02m
American Airlines
Deal found 1/22$309
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:57 pm
PWM
-
PHX
1 stop8h 07m
American Airlines
Sat 3/711:14 pm
PHX
-
PWM
1 stop9h 05m
American Airlines
Deal found 1/22$310

Find flight deals from Portland to Mesa

Keep the following information in mind while searching for Portland to Mesa flight deals. Data was last updated January 23, 2026.

Round-trip from

$251
(American Airlines)

One-way from

$126
(United Airlines)

Popular in

April

Cheapest in

June

Average price

$346
From Portland to Mesa
Search Deals
One-way flight from Portland to Mesa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
Use the filters below to find and compare flights from Portland to Mesa that are best for you.

Fly from

Portland

Fly to

Mesa

Route

Depart

Return

Price

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Tue 3/10

12:51 pm-6:18 pm

1 stop8h 27m

Phoenix Sky Harbor Intl

Mon 3/16

10:29 pm-1:50 pm

2 stops12h 21m

$306

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Mon 3/23

4:48 pm-9:54 pm

1 stop8h 06m

Phoenix Sky Harbor Intl

Tue 3/31

10:29 pm-11:04 am

2 stops9h 35m

$306

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Tue 4/28

11:30 am-10:41 pm

2 stops14h 11m

Phoenix Sky Harbor Intl

Wed 5/6

11:55 pm-12:18 pm

1 stop9h 23m

$335

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Mon 2/23

5:35 am-3:50 pm

2 stops12h 15m

Phoenix Sky Harbor Intl

Wed 2/25

8:30 pm-1:45 pm

2 stops15h 15m

$355

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Wed 4/1

6:04 am-11:20 am

1 stop8h 16m

Phoenix Sky Harbor Intl

Wed 4/8

7:00 am-9:40 pm

2 stops11h 40m

$355

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 4/25

6:00 am-11:02 am

1 stop8h 02m

Phoenix Sky Harbor Intl

Thu 4/30

5:05 am-5:15 pm

1 stop9h 10m

$369

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 2/28

5:57 pm-12:04 am

1 stop8h 07m

Phoenix Sky Harbor Intl

Fri 3/6

12:51 am-11:59 am

2 stops9h 08m

$372

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 5/23

1:35 pm-8:40 pm

1 stop10h 05m

Phoenix Sky Harbor Intl

Wed 5/27

10:00 am-10:03 pm

1 stop9h 03m

$374

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 5/23

1:35 pm-8:40 pm

1 stop10h 05m

Phoenix Sky Harbor Intl

Thu 5/28

11:15 pm-1:54 pm

1 stop11h 39m

$382

PortlandPhoenix

PWM - PHX

PWMPHX

Portland

Sat 4/11

6:25 am-4:26 pm

2 stops13h 01m

Phoenix Sky Harbor Intl

Wed 4/15

6:05 am-11:23 pm

2 stops14h 18m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/22

Showing 1-10 of 21 results
1
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Best time to book a flight from Portland to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Mesa

How far ahead should I book a flight from Portland, Maine to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Mesa. Price data was last updated on January 16, 2026.

Booking 56 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland, Maine to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland, Maine to Mesa?

Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Mesa (average of $135). Flying from Portland, Maine to Mesa in May is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated January 23, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Portland to Mesa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,093 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,195 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,176 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Portland to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Mesa?

    Located just 2.9 mi from the city center, Portland is the airport most travelers will use when flying to Mesa from Portland. Booking flights from Portland (PWM) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 4 different airlines.

  • How long is the flight from Portland, Maine to Mesa?

    There are many flights that can get you from Portland, Maine to Mesa in 8h 27m. Fly via Delta or Southwest to get the fastest option. The distance between Portland, Maine and Mesa is about 2332 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Portland, Maine to Mesa one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $108. Users have also found prices from $125 and $138 on United Airlines and Southwest, respectively.

  • Can I find deals for flights from Portland to Mesa that include hotel bookings?

    Yes. In addition to deals on Portland to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Mesa.

  • Can I find deals for business class flights from Portland to Mesa?

    Yes. Cheapflights offers flight deals from Portland to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Mesa?

    Currently, November is the cheapest month in which you can book a flight from Portland, Maine to Mesa (average of $135). Flying from Portland, Maine to Mesa in May is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Portland to Mesa

Discover the top 4 airlines that operate flights from Portland to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$230Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$361FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$263Average$407FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$291Average$470FlexibilityNo cancel feeOn-time63%

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