What are the cheapest airlines to fly from Myrtle Beach to Mesa one-way?

To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $181. Delta flights start at $181 while deals on Southwest start at $181 one-way.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Myrtle Beach to Mesa?

American Airlines, Southwest and Delta are the most popular airlines when flying from Myrtle Beach to Mesa.

What is the cheapest time of day to fly from MYR to MS9?

When flying from Myrtle Beach to Mesa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from Myrtle Beach to Mesa?

Located just 2.1 mi from the city center, Myrtle Beach Intl is the airport most travelers will use when flying to Mesa from Myrtle Beach. Booking flights from Myrtle Beach Intl (MYR) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 3 different airlines.

Can I find deals for flights from Myrtle Beach to Mesa that include hotel bookings?

Yes. In addition to deals on Myrtle Beach to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Myrtle Beach to Mesa?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Mesa.

Can I find deals for business class flights from Myrtle Beach to Mesa?

Yes. Cheapflights offers flight deals from Myrtle Beach to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Find flight deals from Myrtle Beach to Mesa

Popular in	August
Cheapest in	April
Average price	$441

Highest demand for flights based on searches. 12% potential increase in price ($68 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Reviews of airlines servicing Mesa

Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,225 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Southwest

7.9

Good

4,225 reviews

Southwest

7.9

Good

4,225 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Delta

7.8

Good

8,698 reviews

Southwest

7.9

Good

4,225 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

American Airlines

7.0

Good

12,223 reviews

Southwest

7.9

Good

4,225 reviews

Reviews

1 / 20

8.0

Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

What airport do you fly from for flights from Myrtle Beach to Mesa?
Located just 2.1 mi from the city center, Myrtle Beach Intl is the airport most travelers will use when flying to Mesa from Myrtle Beach. Booking flights from Myrtle Beach Intl (MYR) to Mesa should be relatively easy as there are 0 daily outbound flights to Mesa from 3 different airlines.
What are the cheapest airlines to fly from Myrtle Beach to Mesa one-way?
To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $181. Delta flights start at $181 while deals on Southwest start at $181 one-way.
Can I find deals for flights from Myrtle Beach to Mesa that include hotel bookings?
Yes. In addition to deals on Myrtle Beach to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Myrtle Beach to Mesa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Mesa.
Can I find deals for business class flights from Myrtle Beach to Mesa?
Yes. Cheapflights offers flight deals from Myrtle Beach to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 3 airlines flying from Myrtle Beach to Mesa

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$324	Average$450	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$337	Average$526	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$413	Average$509	FlexibilityNo cancel fee	On-time63%

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Find cheap flights from Myrtle Beach to Mesa with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Myrtle Beach to Mesa

Popular in

Cheapest in

Average price

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated October 30, 2026.

Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Myrtle Beach to Mesa?

What are the cheapest airlines to fly from Myrtle Beach to Mesa one-way?

Can I find deals for flights from Myrtle Beach to Mesa that include hotel bookings?

How can I find direct flights from Myrtle Beach to Mesa?

Can I find deals for business class flights from Myrtle Beach to Mesa?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Myrtle Beach to Mesa by cabin class

Find flights from Myrtle Beach to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Myrtle Beach and Mesa flights

Browse other Myrtle Beach and Mesa flight options. Last updated on October 30, 2026.

Other flights from Myrtle Beach

Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.

Popular flight searches

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Myrtle Beach to Mesa flights

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Top 3 airlines flying from Myrtle Beach to Mesa

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Cheap flights from Myrtle Beach (MYR) to Mesa, AZ

Find cheap flights from Myrtle Beach to Mesa with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Myrtle Beach to Mesa

Popular in

Cheapest in

Average price

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated October 30, 2026.

Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Myrtle Beach to Mesa?

What are the cheapest airlines to fly from Myrtle Beach to Mesa one-way?

Can I find deals for flights from Myrtle Beach to Mesa that include hotel bookings?

How can I find direct flights from Myrtle Beach to Mesa?

Can I find deals for business class flights from Myrtle Beach to Mesa?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Myrtle Beach to Mesa by cabin class

Find flights from Myrtle Beach to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Myrtle Beach and Mesa flights

Browse other Myrtle Beach and Mesa flight options. Last updated on October 30, 2026.

Other flights from Myrtle Beach

Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Myrtle Beach to Mesa flights

Consider these flights traveling from Myrtle Beach to Mesa.

Top 3 airlines flying from Myrtle Beach to Mesa

100% Free

Book with Flexibility

Travel Smart