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Medellín

$173+ Cheap flights from South Carolina to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Jun 21 — Jun 281
Sun 6/21
Sun 6/28
1 adult, Economy
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Cheap flight deals from South Carolina to Medellín

Cheapest flights from South Carolina to Medellín
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.

This KAYAK deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:00 am
CLT
-
MDE
1 stop6h 45m
JetBlue
Wed 8/192:25 pm
MDE
-
CLT
1 stop7h 35m
JetBlue
Deal found 5/21$421
This KAYAK deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:00 am
CLT
-
MDE
1 stop6h 45m
JetBlue
Sat 9/121:30 pm
MDE
-
CLT
1 stop8h 30m
JetBlue
Deal found 5/20$443
This Cheapflightsfares deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:00 am
CLT
-
MDE
1 stop6h 45m
JetBlue
Wed 9/91:30 pm
MDE
-
CLT
1 stop8h 30m
JetBlue
Deal found 5/17$444
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:30 pm
CLT
-
MDE
1 stop7h 46m
American Airlines
Tue 9/153:05 pm
MDE
-
CLT
1 stop15h 03m
American Airlines
Deal found 5/18$479
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:48 pm
CLT
-
MDE
1 stop15h 12m
Multiple Airlines
Wed 8/124:50 am
MDE
-
CLT
2 stops11h 22m
Multiple Airlines
Deal found 5/20$483
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:05 am
CLT
-
MDE
1 stop15h 46m
American Airlines
Sat 9/125:50 am
MDE
-
CLT
2 stops12h 33m
American Airlines
Deal found 5/19$484
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:45 am
CLT
-
MDE
1 stop10h 25m
United Airlines
Mon 8/319:45 am
MDE
-
CLT
2 stops27h 20m
United Airlines
Deal found 5/20$491
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:15 am
CLT
-
MDE
1 stop18h 24m
American Airlines
Mon 11/231:30 am
MDE
-
CLT
1 stop7h 41m
American Airlines
Deal found 5/21$495
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:50 am
CLT
-
MDE
1 stop8h 55m
JetBlue
Thu 8/272:25 pm
MDE
-
CLT
1 stop7h 35m
JetBlue
Deal found 5/17$499
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:50 pm
CLT
-
MDE
1 stop7h 00m
American Airlines
Tue 7/2112:30 am
MDE
-
CLT
1 stop9h 24m
American Airlines
Deal found 5/20$504
This Avianca deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:14 pm
CHS
-
MDE
1 stop13h 56m
Multiple Airlines
Tue 9/810:40 pm
MDE
-
CHS
1 stop10h 35m
Multiple Airlines
Deal found 5/19$559
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am
GSP
-
MDE
1 stop15h 05m
United Airlines
Mon 12/141:15 am
MDE
-
GSP
1 stop14h 03m
United Airlines
Deal found 5/17$560

Find flight deals from South Carolina to Medellín

Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated May 22, 2026.

Round-trip from

$421
(KAYAK)

One-way from

$173
(Kiwi.com)
From South Carolina to Medellín
Search Deals
One-way flight from South Carolina to Medellín
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 8/24

6:01 pm-9:10 pm

2 stops28h 09m

Medellín Jose Maria Cordova Intl

Thu 8/27

9:45 am-9:44 am

2 stops22h 59m

$512

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 8/26

9:10 am-9:10 pm

2 stops37h 00m

Medellín Jose Maria Cordova Intl

Mon 8/31

9:45 am-11:56 pm

2 stops37h 11m

$513

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 8/11

9:10 am-9:10 pm

2 stops37h 00m

Medellín Jose Maria Cordova Intl

Sat 9/12

9:45 am-10:24 am

2 stops23h 39m

$545

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 7/19

6:00 am-8:16 pm

1 stop15h 16m

Medellín Jose Maria Cordova Intl

Fri 7/31

12:30 am-10:22 am

1 stop8h 52m

$577

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 7/13

6:50 am-9:10 pm

1 stop15h 20m

Medellín Jose Maria Cordova Intl

Mon 7/20

9:45 am-10:15 pm

1 stop11h 30m

$577

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Mon 9/14

4:59 pm-9:10 pm

2 stops29h 11m

Medellín Jose Maria Cordova Intl

Mon 9/21

9:45 am-9:59 pm

1 stop11h 14m

$585
Quickest round-trip

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 8/5

6:50 am-2:25 pm

1 stop8h 35m

Medellín Jose Maria Cordova Intl

Fri 8/7

2:25 pm-11:00 pm

1 stop7h 35m

$585

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 6/22

7:53 am-8:15 pm

2 stops13h 22m

Medellín Jose Maria Cordova Intl

Wed 7/15

12:30 am-2:04 pm

2 stops12h 34m

$585

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 8/7

8:05 am-9:10 pm

2 stops38h 05m

Medellín Jose Maria Cordova Intl

Sat 8/22

9:45 am-10:42 am

2 stops23h 57m

$590

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 11/17

6:00 am-10:05 pm

2 stops16h 05m

Medellín Jose Maria Cordova Intl

Mon 11/23

10:45 am-9:44 am

2 stops22h 59m

$600

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/20

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Medellín

What is the cheapest month to book a flight from South Carolina to Medellín?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $81). Flying from South Carolina to Medellín in May is currently the most expensive (average of $641). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Medellín?

How far ahead should I book a flight from South Carolina to Medellín?

The price you pay for your flight from South Carolina to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Medellín?

    A quick flight from South Carolina to Medellín can take about 8h 35m. United Airlines provides one of the quickest options available for as low as $585. Airlines will cover a distance of 2037 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Medellín?

    While some choose either Charleston - Medellín Jose Maria Cordova Intl or Greenville - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Medellín Jose Maria Cordova Intl is the most popular route from South Carolina to Medellín.

  • Can I find deals for flights from South Carolina to Medellín that include hotel bookings?

    Yes. In addition to deals on South Carolina to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Medellín.

  • Can I find deals for business class flights from South Carolina to Medellín?

    Yes. Cheapflights offers flight deals from South Carolina to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Medellín?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $81). Flying from South Carolina to Medellín in May is currently the most expensive (average of $641). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from South Carolina to Medellín

Discover the top airline that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$515Average$677FlexibilityNo cancel feeOn-time71%

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