$213+ Cheap flights from South Carolina to Medellín
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to MedellínExplore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop15h 10m
Fri 10/239:45 am -
1 stop11h 36m
Deal found 9/16![United Airlines logo]()
$452
This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:30 am -
1 stop9h 23m
Mon 11/232:25 pm -
1 stop8h 34m
Deal found 9/16![JetBlue logo]()
$475
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop15h 05m
Mon 11/1610:40 am -
1 stop11h 19m
Deal found 9/16![United Airlines logo]()
$522
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:35 am -
2 stops15h 00m
Tue 10/67:50 am -
2 stops25h 20m
Deal found 9/14![Delta logo]()
$562
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:52 pm -
2 stops28h 43m
Tue 10/67:50 am -
2 stops25h 20m
Deal found 9/14![Delta logo]()
$569
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 11/77:55 pm -
2 stops12h 20m
Wed 11/186:25 am -
2 stops28h 17m
Deal found 9/15![Copa Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 pm -
2 stops27h 10m
Thu 11/1910:40 am -
1 stop11h 19m
Deal found 9/13![United Airlines logo]()
$588
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:40 am -
1 stop15h 30m
Wed 11/1810:40 am -
1 stop11h 19m
Deal found 9/15![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am -
2 stops16h 10m
Wed 11/1810:40 am -
1 stop11h 19m
Deal found 9/15![United Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:30 pm -
1 stop7h 04m
Mon 11/91:30 am -
2 stops12h 00m
Deal found 9/12![American Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:40 am -
1 stop15h 30m
Tue 11/1010:40 am -
1 stop29h 14m
Deal found 9/14![United Airlines logo]()
$600
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:10 am -
2 stops38h 00m
Wed 11/1810:40 am -
1 stop11h 19m
Deal found 9/14![United Airlines logo]()
$602
Best flights from South Carolina to MedellínDiscover carefully curated flight deals from South Carolina to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from South Carolina to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop15h 10m
Fri 10/239:45 am -
1 stop11h 36m
Deal found 9/12![United Airlines logo]()
$452
This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:30 am -
1 stop9h 23m
Mon 11/232:25 pm -
1 stop8h 34m
Deal found 9/16![JetBlue logo]()
$475
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:24 am -
2 stops21h 51m
Wed 12/26:25 am -
2 stops27h 57m
Deal found 9/16![Copa Airlines logo]()
$657
This oojo deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:20 pm -
2 stops19h 50m
Fri 5/2810:40 pm -
1 stop18h 40m
Deal found 9/16![Multiple Airlines logo]()
$659
This BusinessClass deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:55 am -
2 stops13h 31m
Thu 1/283:09 pm -
2 stops19h 16m
Deal found 9/16![GOL logo]()
$664
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:08 pm -
2 stops19h 40m
Sat 10/311:50 pm -
2 stops20h 08m
Deal found 9/12![American Airlines logo]()
$707
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/224:50 pm -
1 stop29h 20m
Fri 2/510:40 am -
1 stop29h 32m
Deal found 9/16![United Airlines logo]()
$470
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
2 stops16h 10m
Tue 2/210:40 am -
2 stops24h 21m
Deal found 9/16![United Airlines logo]()
$482
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/224:50 pm -
1 stop29h 20m
Tue 2/210:40 am -
2 stops24h 21m
Deal found 9/16![United Airlines logo]()
$491
This JetBlue deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:20 am -
1 stop9h 14m
Tue 10/271:26 pm -
1 stop8h 38m
Deal found 9/14![JetBlue logo]()
$690
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop15h 05m
Mon 11/1610:40 am -
1 stop11h 19m
Deal found 9/16![United Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:45 am -
2 stops13h 30m
Fri 5/286:00 am -
2 stops13h 50m
Deal found 9/13![American Airlines logo]()
$721
This JetBlue deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:00 am -
1 stop6h 33m
Thu 11/192:25 pm -
1 stop8h 34m
Deal found 9/15![JetBlue logo]()
$690
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
2 stops13h 22m
Fri 11/277:30 am -
1 stop12h 16m
Deal found 9/11![American Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2710:23 am -
2 stops11h 52m
Wed 3/310:45 am -
2 stops23h 47m
Deal found 9/16![United Airlines logo]()
$574
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/234:50 pm -
1 stop29h 20m
Wed 2/1010:40 am -
1 stop11h 14m
Deal found 9/16![United Airlines logo]()
$578
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:00 am -
2 stops14h 15m
Sun 10/116:00 am -
1 stop16h 59m
Deal found 9/16![American Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:40 am -
1 stop15h 30m
Wed 11/1810:40 am -
1 stop11h 19m
Deal found 9/15![United Airlines logo]()
$614
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops15h 17m
Wed 12/27:30 am -
1 stop14h 20m
Deal found 9/16![American Airlines logo]()
$824
This Trip.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1111:59 am -
2 stops27h 21m
Sun 10/181:00 pm -
1 stop18h 03m
Deal found 9/13![Multiple Airlines logo]()
$1,217
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:10 am -
2 stops38h 00m
Sun 11/1510:40 am -
2 stops36h 24m
Deal found 9/12![United Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:12 pm -
2 stops17h 36m
Sun 10/186:00 am -
2 stops16h 47m
Deal found 9/13![American Airlines logo]()
$886
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:07 am -
2 stops13h 08m
Tue 11/310:40 am -
2 stops23h 43m
Deal found 9/12![United Airlines logo]()
$642
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:33 pm -
2 stops28h 37m
Thu 12/1010:40 am -
2 stops23h 25m
Deal found 9/12![United Airlines logo]()
$654
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
2 stops16h 10m
Mon 11/2310:40 am -
2 stops23h 06m
Deal found 9/12![United Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:55 pm -
2 stops26h 15m
Mon 11/2310:40 am -
2 stops23h 06m
Deal found 9/15![United Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:47 pm -
2 stops26h 23m
Tue 2/1610:45 am -
2 stops23h 01m
Deal found 9/16![United Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/245:10 pm -
2 stops29h 00m
Sun 2/710:40 am -
2 stops34h 15m
Deal found 9/13![United Airlines logo]()
$697
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:12 pm -
1 stop29h 03m
Fri 11/2010:40 am -
2 stops23h 11m
Deal found 9/15![United Airlines logo]()
$703
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:12 pm -
1 stop29h 03m
Sat 11/2110:40 am -
2 stops23h 22m
Deal found 9/15![United Airlines logo]()
$703
Last-minute flights from South Carolina to MedellínDiscover last-minute flight deals from South Carolina to Medellín. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Medellín. Data last updated September 17, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:35 am -
2 stops15h 00m
Tue 10/67:50 am -
2 stops25h 20m
Deal found 9/14![Delta logo]()
$562
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:52 pm -
2 stops28h 43m
Tue 10/67:50 am -
2 stops25h 20m
Deal found 9/14![Delta logo]()
$569
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:25 am -
2 stops16h 45m
Tue 10/67:50 am -
2 stops25h 20m
Deal found 9/14![Delta logo]()
$613
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:35 pm -
2 stops31h 10m
Tue 10/67:50 am -
2 stops25h 20m
Deal found 9/14![Delta logo]()
$620
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops27h 15m
Sat 10/246:20 pm -
2 stops15h 22m
Deal found 9/14![Copa Airlines logo]()
$622
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop15h 10m
Fri 10/239:45 am -
1 stop11h 36m
Deal found 9/16![United Airlines logo]()
$452
This Copa Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:50 pm -
2 stops16h 05m
Mon 10/269:15 am -
2 stops24h 27m
Deal found 9/12![Copa Airlines logo]()
$628
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop15h 05m
Mon 11/1610:40 am -
1 stop11h 19m
Deal found 9/16![United Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:05 pm -
1 stop29h 10m
Sun 11/1510:40 am -
2 stops27h 16m
Deal found 9/16![United Airlines logo]()
$617
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:05 am -
2 stops13h 15m
Mon 11/210:40 pm -
3 stops33h 57m
Deal found 9/16![Multiple Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:00 am -
1 stop10h 15m
Wed 11/43:12 pm -
1 stop8h 47m
Deal found 9/13![American Airlines logo]()
$634
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:00 am -
1 stop6h 33m
Sat 11/72:30 pm -
1 stop8h 34m
Deal found 9/16![JetBlue logo]()
$612
One-way flights from South Carolina to MedellínSearch for one-way flight options from South Carolina to Medellín. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from South Carolina to Medellín. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop15h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:05 am -
3 stops51h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:24 pm -
3 stops43h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$263
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:51 pm -
1 stop14h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$284
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:33 pm -
2 stops13h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:39 pm -
3 stops54h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:45 am -
2 stops20h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:11 pm -
3 stops45h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:08 pm -
3 stops40h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:23 pm -
3 stops56h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:07 pm -
3 stops29h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/317:47 pm -
2 stops26h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$335
Find flight deals from South Carolina to Medellín
Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated September 17, 2026.
Round-trip from | $432 (United Airlines) |
|---|---|
One-way from | $213 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Mon 10/19
7:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$213
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Wed 10/28
8:24 pm-2:45 pm
3 stops43h 21m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$263
SavannahMedellín
SAV Savannah/Hilton Head - MDE Medellín Jose Maria Cordova Intl
SAVMDE
Savannah/Hilton Head
Tue 11/24
6:51 pm-9:05 am
1 stop14h 14m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
SavannahMedellín
SAV Savannah/Hilton Head - MDE Medellín Jose Maria Cordova Intl
SAVMDE
Savannah/Hilton Head
Wed 9/30
12:23 pm-7:40 pm
3 stops56h 17m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$328
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Sun 1/31
7:47 pm-10:10 pm
2 stops26h 23m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$335
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Fri 9/25
10:07 pm-2:56 am
2 stops29h 49m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$341
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Fri 10/16
10:25 am-11:35 pm
2 stops14h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$358
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Tue 9/29
5:46 pm-8:45 am
2 stops15h 59m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$360
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Fri 11/13
11:37 am-2:45 pm
3 stops27h 08m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$368
SavannahMedellín
SAV Savannah/Hilton Head - MDE Medellín Jose Maria Cordova Intl
SAVMDE
Savannah/Hilton Head
Fri 10/30
2:20 pm-11:40 am
1 stop22h 20m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$374
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
CHS-MDE
GSP-MDE
CLT-MDE
SAV-MDE
MYR-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Medellín
USSC-CO1
CHS-MDE
GSP-MDE
CLT-MDE
SAV-MDE
What is the cheapest month to book a flight from South Carolina to Medellín?
Currently, March is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $523). Flying from South Carolina to Medellín in October is currently the most expensive (average of $939). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Medellín?
Airfare is below average for this route at the moment.
South Carolina to Medellín flights typically cost between $778 and $956 in January.The cheapest round-trip price found within the last 5 days was $432 on United Airlines (Jan 22-Feb 5).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Medellín
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
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Search flights from South Carolina to Medellín by cabin class
Find flights from South Carolina to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Medellín flights
Browse other South Carolina and Medellín flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Medellín flights
Consider these flights traveling from South Carolina to Medellín.
Top airline flying from South Carolina to Medellín
Discover the top airline that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$523 | Average$747 | FlexibilityNo cancel fee | On-time71% |