$203+ Cheap flights from South Carolina to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Aug 26 — Sep 21
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to MedellínExplore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:41 am
CHS
- MDE
1 stop11h 53m
American Airlines
Wed 11/47:30 am
MDE
- CHS
1 stop14h 32m
American Airlines
Deal found 7/25![American Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:35 pm
CHS
- MDE
2 stops28h 55m
Delta
Tue 9/298:30 am
MDE
- CHS
2 stops23h 18m
Delta
Deal found 7/22![Delta logo]()
$406
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:31 pm
CHS
- MDE
2 stops20h 17m
American Airlines
Tue 9/291:53 pm
MDE
- CHS
2 stops18h 54m
American Airlines
Deal found 7/22![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:41 pm
CHS
- MDE
2 stops18h 07m
American Airlines
Mon 9/286:00 am
MDE
- CHS
2 stops15h 33m
American Airlines
Deal found 7/22![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:19 pm
CHS
- MDE
2 stops9h 15m
American Airlines
Thu 11/123:12 pm
MDE
- CHS
2 stops17h 19m
American Airlines
Deal found 7/25![American Airlines logo]()
$431
This LATAM Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:50 am
CHS
- MDE
2 stops14h 40m
LATAM Airlines
Tue 9/298:30 am
MDE
- CHS
2 stops24h 38m
LATAM Airlines
Deal found 7/22![LATAM Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:12 am
CHS
- MDE
1 stop10h 03m
American Airlines
Tue 10/206:00 am
MDE
- CHS
1 stop16h 59m
American Airlines
Deal found 7/24![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:26 pm
CHS
- MDE
2 stops18h 46m
American Airlines
Sun 11/157:30 am
MDE
- CHS
1 stop16h 29m
American Airlines
Deal found 7/26![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:06 am
CLT
- MDE
1 stop12h 09m
American Airlines
Wed 9/236:00 am
MDE
- CLT
1 stop11h 15m
American Airlines
Deal found 7/22![American Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:00 am
CLT
- MDE
2 stops16h 10m
United Airlines
Wed 9/239:45 am
MDE
- CLT
2 stops23h 23m
United Airlines
Deal found 7/22![United Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:04 pm
CLT
- MDE
1 stop29h 06m
United Airlines
Thu 10/229:45 am
MDE
- CLT
2 stops23h 23m
United Airlines
Deal found 7/22![United Airlines logo]()
$503
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:04 pm
CLT
- MDE
1 stop29h 06m
United Airlines
Tue 10/209:45 am
MDE
- CLT
1 stop11h 14m
United Airlines
Deal found 7/22![United Airlines logo]()
$505
Best flights from South Carolina to MedellínDiscover carefully curated flight deals from South Carolina to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
Discover carefully curated flight deals from South Carolina to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:47 am
CLT
- MDE
1 stop15h 23m
United Airlines
Sat 12/1210:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/23![United Airlines logo]()
$509
This oojo deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:43 pm
CHS
- MDE
2 stops10h 52m
LATAM Airlines
Mon 9/286:25 am
MDE
- CHS
2 stops25h 23m
LATAM Airlines
Deal found 7/23![LATAM Airlines logo]()
$513
This Avianca deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:00 pm
SAV
- MDE
2 stops12h 45m
Multiple Airlines
Sun 12/611:00 pm
MDE
- SAV
1 stop11h 31m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:12 am
CHS
- MDE
1 stop10h 03m
American Airlines
Sun 10/256:00 am
MDE
- CHS
2 stops16h 57m
American Airlines
Deal found 7/24![American Airlines logo]()
$582
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:25 am
CHS
- MDE
2 stops13h 20m
Delta
Mon 9/145:50 am
MDE
- CHS
2 stops17h 09m
Delta
Deal found 7/23![Delta logo]()
$615
This Copa Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:55 pm
CLT
- MDE
2 stops22h 00m
Copa Airlines
Fri 8/2812:40 pm
MDE
- CLT
2 stops20h 04m
Copa Airlines
Deal found 7/26![Copa Airlines logo]()
$626
This oojo deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:19 pm
CHS
- MDE
2 stops23h 21m
LATAM Airlines
Sun 10/259:45 am
MDE
- CHS
2 stops13h 14m
LATAM Airlines
Deal found 7/23![LATAM Airlines logo]()
$513
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:55 pm
CLT
- MDE
2 stops26h 15m
United Airlines
Wed 9/169:45 am
MDE
- CLT
2 stops23h 39m
United Airlines
Deal found 7/22![United Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:50 pm
CLT
- MDE
2 stops26h 20m
United Airlines
Wed 10/219:45 am
MDE
- CLT
2 stops22h 59m
United Airlines
Deal found 7/22![United Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 pm
CHS
- MDE
1 stop19h 18m
American Airlines
Sat 9/266:00 am
MDE
- CHS
1 stop16h 43m
American Airlines
Deal found 7/25![American Airlines logo]()
$584
This oojo deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:01 pm
CHS
- MDE
2 stops10h 34m
LATAM Airlines
Mon 9/145:50 am
MDE
- CHS
2 stops25h 58m
LATAM Airlines
Deal found 7/26![LATAM Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am
CHS
- MDE
2 stops16h 35m
Delta
Fri 9/257:50 am
MDE
- CHS
2 stops15h 09m
Delta
Deal found 7/22![Delta logo]()
$628
This oojo deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:01 pm
CHS
- MDE
2 stops10h 34m
LATAM Airlines
Sun 8/307:50 am
MDE
- CHS
2 stops15h 09m
LATAM Airlines
Deal found 7/24![LATAM Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
CHS
- MDE
2 stops15h 15m
American Airlines
Sun 10/186:00 am
MDE
- CHS
2 stops15h 14m
American Airlines
Deal found 7/24![American Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am
CLT
- MDE
2 stops16h 10m
United Airlines
Fri 10/239:45 am
MDE
- CLT
1 stop29h 21m
United Airlines
Deal found 7/22![United Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:40 am
GSP
- MDE
2 stops16h 25m
Delta
Sun 11/155:35 am
MDE
- GSP
2 stops15h 46m
Delta
Deal found 7/23![Delta logo]()
$645
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am
CHS
- MDE
1 stop15h 10m
United Airlines
Wed 9/309:45 am
MDE
- CHS
1 stop11h 36m
United Airlines
Deal found 7/22![United Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:06 am
GSP
- MDE
2 stops15h 09m
American Airlines
Mon 11/237:30 am
MDE
- GSP
1 stop11h 41m
American Airlines
Deal found 7/23![American Airlines logo]()
$655
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:28 pm
GSP
- MDE
2 stops10h 37m
Delta
Sun 9/137:50 am
MDE
- GSP
2 stops28h 00m
Delta
Deal found 7/23![Delta logo]()
$680
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:12 pm
MYR
- MDE
2 stops17h 43m
Multiple Airlines
Sun 9/131:00 pm
MDE
- MYR
1 stop17h 58m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$860
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:20 am
GSP
- MDE
2 stops15h 50m
United Airlines
Mon 11/2310:40 am
MDE
- GSP
2 stops23h 11m
United Airlines
Deal found 7/23![United Airlines logo]()
$590
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:33 pm
MYR
- MDE
2 stops18h 15m
American Airlines
Sat 8/296:00 am
MDE
- MYR
2 stops15h 38m
American Airlines
Deal found 7/23![American Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:25 am
CLT
- MDE
2 stops11h 45m
United Airlines
Fri 9/49:45 am
MDE
- CLT
2 stops23h 23m
United Airlines
Deal found 7/23![United Airlines logo]()
$591
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:00 pm
GSP
- MDE
2 stops35h 15m
Delta
Thu 9/105:10 am
MDE
- GSP
2 stops27h 15m
Delta
Deal found 7/26![Delta logo]()
$731
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/29:02 am
GSP
- MDE
2 stops14h 37m
American Airlines
Sat 1/237:00 am
MDE
- GSP
2 stops15h 19m
American Airlines
Deal found 7/22![American Airlines logo]()
$676
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:01 pm
SAV
- MDE
1 stop18h 12m
American Airlines
Thu 11/267:30 am
MDE
- SAV
1 stop13h 52m
American Airlines
Deal found 7/24![American Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:10 am
SAV
- MDE
2 stops14h 00m
United Airlines
Thu 9/109:45 am
MDE
- SAV
2 stops28h 33m
United Airlines
Deal found 7/22![United Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 am
CHS
- MDE
1 stop15h 10m
United Airlines
Mon 9/289:45 am
MDE
- CHS
2 stops27h 19m
United Airlines
Deal found 7/25![United Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:35 am
MYR
- MDE
2 stops13h 40m
American Airlines
Sun 9/136:00 am
MDE
- MYR
2 stops15h 49m
American Airlines
Deal found 7/23![American Airlines logo]()
$687
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:08 am
MYR
- MDE
2 stops13h 07m
American Airlines
Tue 9/151:53 pm
MDE
- MYR
2 stops20h 44m
American Airlines
Deal found 7/25![American Airlines logo]()
$687
Last-minute flights from South Carolina to MedellínDiscover last-minute flight deals from South Carolina to Medellín. Data last updated July 27, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Medellín. Data last updated July 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:05 am
CLT
- MDE
2 stops14h 05m
United Airlines
Thu 12/1010:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/22![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:04 pm
CLT
- MDE
1 stop29h 06m
United Airlines
Mon 12/710:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/22![United Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:55 pm
CLT
- MDE
2 stops26h 15m
United Airlines
Wed 12/910:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/25![United Airlines logo]()
$529
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:36 pm
CLT
- MDE
2 stops28h 34m
United Airlines
Tue 12/810:45 am
MDE
- CLT
2 stops22h 59m
United Airlines
Deal found 7/22![United Airlines logo]()
$535
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:25 am
CLT
- MDE
2 stops11h 45m
United Airlines
Wed 12/910:45 am
MDE
- CLT
2 stops23h 28m
United Airlines
Deal found 7/22![United Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:04 pm
CLT
- MDE
1 stop29h 06m
United Airlines
Tue 12/810:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/22![United Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:45 am
CLT
- MDE
1 stop10h 25m
United Airlines
Tue 12/810:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/22![United Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:45 am
CLT
- MDE
1 stop10h 25m
United Airlines
Fri 12/1110:45 am
MDE
- CLT
1 stop11h 07m
United Airlines
Deal found 7/22![United Airlines logo]()
$534
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:48 pm
CHS
- MDE
2 stops18h 02m
American Airlines
Mon 8/316:00 am
MDE
- CHS
2 stops16h 54m
American Airlines
Deal found 7/25![American Airlines logo]()
$534
This oojo deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:01 pm
CHS
- MDE
2 stops10h 34m
LATAM Airlines
Sun 8/307:50 am
MDE
- CHS
2 stops15h 09m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$537
This LATAM Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:15 am
CHS
- MDE
2 stops16h 20m
LATAM Airlines
Tue 9/158:05 pm
MDE
- CHS
2 stops26h 54m
LATAM Airlines
Deal found 7/22![LATAM Airlines logo]()
$435
This LATAM Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:15 am
CHS
- MDE
2 stops15h 15m
LATAM Airlines
Wed 9/165:50 am
MDE
- CHS
2 stops27h 18m
LATAM Airlines
Deal found 7/22![LATAM Airlines logo]()
$545
One-way flights from South Carolina to MedellínSearch for one-way flight options from South Carolina to Medellín. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
Search for one-way flight options from South Carolina to Medellín. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:37 am
GSP
- MDE
3 stops36h 03m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:21 pm
MYR
- MDE
2 stops27h 04m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:28 pm
CLT
- MDE
2 stops14h 12m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:59 pm
CLT
- MDE
2 stops22h 41m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/78:28 pm
GSP
- MDE
3 stops51h 22m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/231:58 pm
CLT
- MDE
2 stops30h 42m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:18 am
CHS
- MDE
2 stops11h 37m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:45 pm
GSP
- MDE
2 stops19h 00m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:07 am
GSP
- MDE
3 stops46h 08m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:56 am
CLT
- MDE
3 stops38h 54m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:17 am
GSP
- MDE
2 stops26h 38m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:48 pm
CLT
- MDE
2 stops29h 03m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$265
Find flight deals from South Carolina to Medellín
Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated July 27, 2026.
Round-trip from | $389 (American Airlines) |
|---|---|
One-way from | $203 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Tue 11/10
6:47 am-10:10 pm
1 stop15h 23m
Medellín Jose Maria Cordova Intl
Sat 12/12
10:45 am-9:52 pm
1 stop11h 07m
$509
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Thu 9/17
12:43 pm-10:35 pm
2 stops10h 52m
Medellín Jose Maria Cordova Intl
Mon 9/28
6:25 am-8:48 am
2 stops25h 23m
$513
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Sat 10/17
6:19 pm-4:40 pm
2 stops23h 21m
Medellín Jose Maria Cordova Intl
Sun 10/25
9:45 am-11:59 pm
2 stops13h 14m
$513
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Sun 9/6
7:55 pm-9:10 pm
2 stops26h 15m
Medellín Jose Maria Cordova Intl
Wed 9/16
9:45 am-10:24 am
2 stops23h 39m
$519
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Fri 10/16
7:50 pm-9:10 pm
2 stops26h 20m
Medellín Jose Maria Cordova Intl
Wed 10/21
9:45 am-9:44 am
2 stops22h 59m
$521
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Tue 9/1
1:01 pm-10:35 pm
2 stops10h 34m
Medellín Jose Maria Cordova Intl
Mon 9/14
5:50 am-8:48 am
2 stops25h 58m
$537
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Wed 8/26
1:01 pm-10:35 pm
2 stops10h 34m
Medellín Jose Maria Cordova Intl
Sun 8/30
7:50 am-11:59 pm
2 stops15h 09m
$537
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Mon 10/19
6:00 am-9:10 pm
2 stops16h 10m
Medellín Jose Maria Cordova Intl
Fri 10/23
9:45 am-4:06 pm
1 stop29h 21m
$552
Quickest round-trip
SavannahMedellín
SAV - MDE
SAVMDE
Savannah/Hilton Head
Wed 12/2
7:00 pm-7:45 am
2 stops12h 45m
Medellín Jose Maria Cordova Intl
Sun 12/6
11:00 pm-10:31 am
1 stop11h 31m
$557
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Sat 10/17
11:12 am-8:15 pm
1 stop10h 03m
Medellín Jose Maria Cordova Intl
Sun 10/25
6:00 am-11:57 pm
2 stops16h 57m
$582
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
CHS-MDE
CLT-MDE
GSP-MDE
MYR-MDE
SAV-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Medellín
USSC-CO1
CHS-MDE
CLT-MDE
GSP-MDE
MYR-MDE
What is the cheapest month to book a flight from South Carolina to Medellín?
Currently, March is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $523). Flying from South Carolina to Medellín in September is currently the most expensive (average of $917). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Medellín?
The price you pay for your flight from South Carolina to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 43 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Medellín
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Medellín by cabin class
Find flights from South Carolina to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Medellín flights
Browse other South Carolina and Medellín flight options. Last updated on July 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Medellín flights
Consider these flights traveling from South Carolina to Medellín.
Top airline flying from South Carolina to Medellín
Discover the top airline that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$515 | Average$680 | FlexibilityNo cancel fee | On-time71% |