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Medellín

$92+ Cheap flights from South Carolina to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from South Carolina to Medellín

Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated October 30, 2025.

Round-trip from

$256
(CheapOair)

One-way from

$92
(CheapOair)
From South Carolina to Medellín
Search Deals
One-way flight from South Carolina to Medellín
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Find flight deals from South Carolina to Medellín

Cheapest flights from South Carolina to Medellín
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Orbitz deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:59 pmCLT - MDE
1 stop6h 57mSpirit Airlines
Wed 12/32:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/29$256
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/12:46 pmMYR - MDE
1 stop10h 10mSpirit Airlines
Tue 12/92:05 amMDE - MYR
1 stop15h 43mSpirit Airlines
Deal found 10/29$258
This Spirit deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:44 pmCLT - MDE
1 stop6h 13mSpirit Airlines
Sat 11/223:14 pmMDE - CLT
1 stop8h 18mSpirit Airlines
Deal found 10/30$263
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:59 pmCLT - MDE
1 stop6h 57mSpirit Airlines
Tue 12/92:05 amMDE - CLT
1 stop11h 58mSpirit Airlines
Deal found 10/29$265
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:50 amCHS - MDE
1 stop18h 06mSpirit Airlines
Wed 12/102:05 amMDE - CHS
1 stop18h 49mSpirit Airlines
Deal found 10/29$266
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:11 pmCLT - MDE
1 stop9h 45mSpirit Airlines
Sat 12/62:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/29$281
This Expedia deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:55 pmCLT - MDE
1 stop14h 00mSpirit Airlines
Fri 12/122:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/30$292
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:50 amCHS - MDE
1 stop18h 06mSpirit Airlines
Sun 12/72:05 amMDE - CHS
1 stop18h 49mSpirit Airlines
Deal found 10/29$293
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:11 pmCLT - MDE
1 stop9h 45mSpirit Airlines
Sat 12/133:10 pmMDE - CLT
1 stop8h 49mSpirit Airlines
Deal found 10/29$297
This Avianca Connect deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:50 amCHS - MDE
1 stop14h 50mMultiple Airlines
Mon 12/81:00 pmMDE - CHS
1 stop7h 54mMultiple Airlines
Deal found 10/29$299
This KAYAK deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:07 amCLT - MDE
1 stop27h 56mSpirit Airlines
Thu 12/411:50 amMDE - CLT
2 stops12h 09mSpirit Airlines
Deal found 10/29$301
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:50 amCHS - MDE
1 stop18h 06mSpirit Airlines
Sun 12/72:05 amMDE - CHS
1 stop18h 49mSpirit Airlines
Deal found 10/29$303

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.

Fly from

South Carolina

Fly to

Medellín

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Mon 12/1

2:46 pm-12:56 am

1 stop10h 10m

Medellín Jose Maria Cordova Intl

Tue 12/9

2:05 am-5:48 pm

1 stop15h 43m

$258

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 11/14

6:44 pm-12:57 am

1 stop6h 13m

Medellín Jose Maria Cordova Intl

Sat 11/22

3:14 pm-11:32 pm

1 stop8h 18m

$263

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 12/1

6:50 am-12:56 am

1 stop18h 06m

Medellín Jose Maria Cordova Intl

Wed 12/10

2:05 am-8:54 pm

1 stop18h 49m

$266

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 2/6

9:46 pm-2:16 pm

2 stops16h 30m

Medellín Jose Maria Cordova Intl

Wed 2/11

3:11 pm-12:59 am

1 stop9h 48m

$280

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Tue 12/2

6:50 am-12:56 am

1 stop18h 06m

Medellín Jose Maria Cordova Intl

Sat 12/6

2:05 am-8:54 pm

1 stop18h 49m

$293

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Tue 12/2

6:50 am-9:40 pm

1 stop14h 50m

Medellín Jose Maria Cordova Intl

Mon 12/8

1:00 pm-8:54 pm

1 stop7h 54m

$299

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 12/1

6:50 am-9:40 pm

1 stop14h 50m

Medellín Jose Maria Cordova Intl

Mon 12/8

1:00 pm-8:54 pm

1 stop7h 54m

$299

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sun 12/7

8:55 pm-1:57 pm

1 stop17h 02m

Medellín Jose Maria Cordova Intl

Sat 12/13

3:10 pm-11:59 pm

1 stop8h 49m

$316

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Mon 12/1

6:50 am-12:56 am

1 stop18h 06m

Medellín Jose Maria Cordova Intl

Fri 12/5

2:05 am-10:59 pm

2 stops20h 54m

$322

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 12/12

2:58 pm-1:09 am

1 stop10h 11m

Medellín Jose Maria Cordova Intl

Sat 12/13

2:05 am-9:39 am

1 stop7h 34m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 46 results
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Best time to book a flight from South Carolina to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Medellín

What is the cheapest month to book a flight from South Carolina to Medellín?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $176). Flying from South Carolina to Medellín in April is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDE?

Find hourly flight availability from South Carolina to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from South Carolina to Medellín by exploring options for tickets in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Medellín?

    A quick flight from South Carolina to Medellín can take about 10h 10m. Spirit Airlines provides one of the quickest options available for as low as $258. Airlines will cover a distance of 1913 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Medellín?

    While some choose either Greenville - Medellín Jose Maria Cordova Intl or Charleston - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Medellín Jose Maria Cordova Intl is the most popular route from South Carolina to Medellín.

  • Can I find deals for flights from South Carolina to Medellín that include hotel bookings?

    Yes. In addition to deals on South Carolina to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Medellín.

  • Can I find deals for business class flights from South Carolina to Medellín?

    Yes. Cheapflights offers flight deals from South Carolina to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Medellín?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $176). Flying from South Carolina to Medellín in April is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Medellín

Discover the top 3 airlines that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$327Average$414FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$471Average$684FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$670Average$776FlexibilityNo cancel feeOn-time81%

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