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Medellín

$104+ Cheap flights from South Carolina to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
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Cheap flight deals from South Carolina to Medellín

Cheapest flights from South Carolina to Medellín
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:34 pmCLT - MDE
1 stop16h 23mSpirit Airlines
jue. 1/293:15 pmMDE - CLT
1 stop9h 25mSpirit Airlines
Deal found 12/15$355
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:43 pmCLT - MDE
1 stop13h 12mMultiple Airlines
jue. 1/2910:10 amMDE - CLT
2 stops23h 20mMultiple Airlines
Deal found 12/15$424
This KAYAK deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2510:18 pmCHS - MDE
1 stop27h 10mSpirit Airlines
mié. 12/312:54 pmMDE - CHS
2 stops30h 29mSpirit Airlines
Deal found 12/16$431
This eDestinos deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/148:55 pmCLT - MDE
1 stop14h 00mSpirit Airlines
lun. 12/223:10 pmMDE - CLT
1 stop8h 19mSpirit Airlines
Deal found 12/14$469
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/209:34 pmCLT - MDE
1 stop16h 23mSpirit Airlines
dom. 12/212:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/15$475
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
mié. 12/312:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/15$485
This KAYAK deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/309:54 amMYR - MDE
1 stop15h 34mSpirit Airlines
mar. 1/62:54 pmMDE - MYR
2 stops27h 14mSpirit Airlines
Deal found 12/14$499
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/309:38 pmCLT - MDE
1 stop16h 36mSpirit Airlines
mar. 1/62:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/16$504
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2510:18 pmCHS - MDE
1 stop27h 10mMultiple Airlines
mié. 12/312:54 pmMDE - CHS
1 stop17h 43mMultiple Airlines
Deal found 12/16$507
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2511:33 amGSP - MDE
2 stops34h 07mMultiple Airlines
mar. 12/302:25 amMDE - GSP
1 stop13h 30mMultiple Airlines
Deal found 12/16$509
This KAYAK deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
mié. 12/312:54 pmMDE - CLT
2 stops29h 39mSpirit Airlines
Deal found 12/14$517
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/249:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
vie. 12/262:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/15$533

Find flight deals from South Carolina to Medellín

Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated diciembre 16, 2025.

Round-trip from

$257
(Cheapflightsfares)

One-way from

$104
(Cheapflightsfares)
From South Carolina to Medellín
Search Deals
One-way flight from South Carolina to Medellín
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.

Fly from

South Carolina

Fly to

Medellín

Route

Depart

Return

Price

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jue. 2/5

6:35 pm-2:15 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

dom. 2/8

3:15 pm-5:36 pm

1 stop26h 21m

$288

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lun. 1/26

7:43 pm-1:55 pm

2 stops18h 12m

Medellín Jose Maria Cordova Intl

jue. 1/29

3:15 pm-12:40 am

1 stop9h 25m

$290

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

mar. 1/27

6:00 am-2:15 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

vie. 2/6

2:50 pm-8:11 am

2 stops41h 21m

$295

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lun. 2/2

7:43 pm-1:55 pm

2 stops18h 12m

Medellín Jose Maria Cordova Intl

mar. 2/10

3:15 pm-12:40 am

1 stop9h 25m

$306

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lun. 2/2

6:00 am-10:07 pm

2 stops16h 07m

Medellín Jose Maria Cordova Intl

mar. 2/10

9:43 am-12:40 am

2 stops14h 57m

$332

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

vie. 1/23

7:43 pm-1:55 pm

2 stops42h 12m

Medellín Jose Maria Cordova Intl

dom. 2/8

3:15 pm-12:40 am

1 stop9h 25m

$333

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

jue. 1/29

1:24 pm-9:40 pm

1 stop8h 16m

Medellín Jose Maria Cordova Intl

lun. 2/2

1:00 pm-1:58 pm

1 stop24h 58m

$342

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

vie. 2/20

9:35 am-2:13 pm

1 stop28h 38m

Medellín Jose Maria Cordova Intl

dom. 2/22

3:15 pm-6:51 pm

1 stop27h 36m

$346

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jue. 2/5

6:35 pm-2:15 pm

1 stop19h 40m

Medellín Jose Maria Cordova Intl

dom. 2/8

9:45 am-8:43 am

2 stops22h 58m

$348

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

vie. 1/2

10:18 pm-9:40 pm

1 stop23h 22m

Medellín Jose Maria Cordova Intl

sáb. 1/17

1:00 pm-5:36 pm

1 stop28h 36m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 48 results
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Best time to book a flight from South Carolina to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Medellín

What is the cheapest month to book a flight from South Carolina to Medellín?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $176). Flying from South Carolina to Medellín in November is currently the most expensive (average of $563). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDE?

Find hourly flight availability from South Carolina to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from South Carolina to Medellín by exploring options for tickets in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Medellín?

    A quick flight from South Carolina to Medellín can take about 10h 25m. Spirit Airlines provides one of the quickest options available for as low as $527. Airlines will cover a distance of 1831 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Medellín?

    While some choose either Greenville - Medellín Jose Maria Cordova Intl or Charleston - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Medellín Jose Maria Cordova Intl is the most popular route from South Carolina to Medellín.

  • Can I find deals for flights from South Carolina to Medellín that include hotel bookings?

    Yes. In addition to deals on South Carolina to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Medellín.

  • Can I find deals for business class flights from South Carolina to Medellín?

    Yes. Cheapflights offers flight deals from South Carolina to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Medellín?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $176). Flying from South Carolina to Medellín in November is currently the most expensive (average of $563). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Medellín

Discover the top 3 airlines that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$327Average$395FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$471Average$677FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$670Average$776FlexibilityNo cancel feeOn-time81%

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