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Medellín

$91+ Cheap flights from South Carolina to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
mar 12 — mar 191
tors 3/12
tors 3/19
1 adult, Economy
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Cheap flight deals from South Carolina to Medellín

Cheapest flights from South Carolina to Medellín
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on februari 10, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tis 4/289:24 pm
CLT
-
MDE
1 stop16h 49m
Spirit Airlines
ons 5/62:10 pm
MDE
-
CLT
1 stop9h 30m
Spirit Airlines
Deal found 2/7$231
This FlightHub deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 3/201:20 pm
CLT
-
MDE
1 stop12h 01m
Spirit Airlines
ons 3/252:17 pm
MDE
-
CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/9$236
This Cheapflightsfares deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 5/66:00 am
CLT
-
MDE
1 stop8h 13m
Spirit Airlines
ons 5/272:10 pm
MDE
-
CLT
1 stop9h 30m
Spirit Airlines
Deal found 2/9$241
This Cheapflightsfares deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 3/181:20 pm
CLT
-
MDE
1 stop12h 01m
Spirit Airlines
ons 3/252:17 pm
MDE
-
CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/9$244
This Expedia deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 3/209:00 pm
CLT
-
MDE
1 stop17h 22m
Spirit Airlines
tis 3/242:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 2/7$245
This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 3/168:07 am
CHS
-
MDE
1 stop6h 15m
Spirit Airlines
ons 3/182:17 pm
MDE
-
CHS
1 stop6h 56m
Spirit Airlines
Deal found 2/7$249
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 3/25:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
tors 3/53:15 pm
MDE
-
CLT
1 stop17h 11m
Spirit Airlines
Deal found 2/7$249
This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 3/239:00 pm
CLT
-
MDE
1 stop17h 22m
Spirit Airlines
mån 3/301:17 am
MDE
-
CLT
1 stop18h 00m
Spirit Airlines
Deal found 2/7$255
This Cheapflightsfares deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 2/235:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
ons 3/43:15 pm
MDE
-
CLT
1 stop17h 11m
Spirit Airlines
Deal found 2/8$259
This Cheapflightsfares deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 4/158:55 am
CLT
-
MDE
1 stop16h 47m
Spirit Airlines
sön 4/261:37 am
MDE
-
CLT
1 stop11h 36m
Spirit Airlines
Deal found 2/9$261
This CheapOair deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 3/129:00 pm
CLT
-
MDE
1 stop28h 21m
Spirit Airlines
mån 3/161:17 am
MDE
-
CLT
1 stop18h 00m
Spirit Airlines
Deal found 2/9$264
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lör 2/287:13 pm
CLT
-
MDE
1 stop19h 00m
Spirit Airlines
lör 3/73:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 2/8$266

Find flight deals from South Carolina to Medellín

Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated februari 10, 2026.

Round-trip from

$231
(Cheapflightsfares)

One-way from

$91
(Cheapflightsfares)
From South Carolina to Medellín
Search Deals
One-way flight from South Carolina to Medellín
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated februari 10, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.

Fly from

South Carolina

Fly to

Medellín

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sön 5/10

9:24 pm-1:13 pm

1 stop16h 49m

Medellín Jose Maria Cordova Intl

lör 5/16

2:10 pm-12:40 am

1 stop9h 30m

$236

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

mån 3/16

8:07 am-1:22 pm

1 stop6h 15m

Medellín Jose Maria Cordova Intl

ons 3/18

2:17 pm-10:13 pm

1 stop6h 56m

$249

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

mån 3/2

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

tors 3/5

3:15 pm-11:56 pm

1 stop8h 41m

$249

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sön 3/1

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

ons 3/4

3:15 pm-11:56 pm

1 stop8h 41m

$271

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

fre 3/13

9:00 pm-12:21 am

1 stop28h 21m

Medellín Jose Maria Cordova Intl

mån 3/16

10:49 am-8:21 am

2 stops20h 32m

$275

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

mån 3/30

12:47 pm-12:21 am

1 stop12h 34m

Medellín Jose Maria Cordova Intl

sön 4/5

1:17 am-9:54 pm

1 stop19h 37m

$278

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

lör 3/14

8:07 am-12:21 am

1 stop17h 14m

Medellín Jose Maria Cordova Intl

mån 3/16

1:17 am-10:13 pm

1 stop19h 56m

$282

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

fre 5/8

9:24 pm-1:13 pm

1 stop16h 49m

Medellín Jose Maria Cordova Intl

fre 5/15

2:10 pm-8:26 am

1 stop17h 16m

$288

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lör 2/28

7:13 pm-2:13 pm

1 stop19h 00m

Medellín Jose Maria Cordova Intl

lör 3/7

2:50 pm-7:26 am

2 stops40h 36m

$292

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

sön 3/8

6:35 pm-1:13 pm

1 stop19h 38m

Medellín Jose Maria Cordova Intl

lör 3/14

1:17 am-10:13 pm

1 stop19h 56m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/7

Showing 1-10 of 41 results
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Best time to book a flight from South Carolina to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Medellín

What is the cheapest month to book a flight from South Carolina to Medellín?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $176). Flying from South Carolina to Medellín in January is currently the most expensive (average of $599). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Medellín?

    A quick flight from South Carolina to Medellín can take about 16h 49m. Spirit Airlines provides one of the quickest options available for as low as $236. Airlines will cover a distance of 2037 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Medellín?

    While some choose either Greenville - Medellín Jose Maria Cordova Intl or Myrtle Beach Intl - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Medellín Jose Maria Cordova Intl is the most popular route from South Carolina to Medellín.

  • Can I find deals for flights from South Carolina to Medellín that include hotel bookings?

    Yes. In addition to deals on South Carolina to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Medellín.

  • Can I find deals for business class flights from South Carolina to Medellín?

    Yes. Cheapflights offers flight deals from South Carolina to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Medellín?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $176). Flying from South Carolina to Medellín in January is currently the most expensive (average of $599). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Medellín

Discover the top 2 airlines that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated februari 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$327Average$395FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$515Average$653FlexibilityNo cancel feeOn-time71%

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