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Medellín

$122+ Cheap flights from Santo Domingo (SDQ) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Sep 7 — Sep 141
Mon 9/7
Mon 9/14
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or May, booked 90 days in advance, depart on a Saturday or Tuesday and return on a Thursday

Cheap flight deals from Santo Domingo to Medellín

Cheapest flights from Santo Domingo to Medellín
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 8, 2026.

This Expedia deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:45 am -
Nonstop2h 35m
Sat 11/710:05 am -
Nonstop2h 32m
Deal found 8/4$248
This Wingo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm -
Nonstop2h 28m
Tue 9/2211:54 am -
Nonstop2h 30m
Deal found 8/7$250
This Wingo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm -
Nonstop2h 28m
Sat 9/510:22 am -
Nonstop2h 30m
Deal found 8/7$253
This Expedia deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:45 am -
Nonstop2h 35m
Mon 8/248:25 pm -
Nonstop2h 32m
Deal found 8/3$256
This Booking.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:48 am -
Nonstop2h 32m
Fri 9/188:25 pm -
Nonstop2h 32m
Deal found 8/7$261
This Wingo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:42 pm -
Nonstop2h 28m
Sat 10/2410:22 am -
Nonstop2h 30m
Deal found 8/7$264
This CheapOair deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:10 pm -
Nonstop2h 32m
Tue 8/2510:05 am -
Nonstop2h 32m
Deal found 8/3$265
This CheapOair deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:05 pm -
Nonstop2h 35m
Fri 8/2810:05 am -
Nonstop2h 32m
Deal found 8/3$266
This Wingo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Tue 10/1311:54 am -
Nonstop2h 30m
Deal found 8/7$267
This Expedia deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:05 pm -
Nonstop2h 35m
Mon 11/28:25 pm -
Nonstop2h 32m
Deal found 8/3$269
This Wingo deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:42 pm -
Nonstop2h 28m
Sat 9/1910:22 am -
Nonstop2h 30m
Deal found 8/3$271
This Arajet deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:05 pm -
Nonstop2h 35m
Mon 9/218:25 pm -
Nonstop2h 32m
Deal found 8/4$272

Find flight deals from Santo Domingo to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 8, 2026.

Round-trip from

$248
(Expedia)

One-way from

$122
(Wingo)

Popular in

December

Cheapest in

February

Average price

$288
From Santo Domingo Las Americas to Medellín
Search Deals
One-way flight from Santo Domingo Las Americas to Medellín
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 8, 2026.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Tue 9/1

4:14 pm-5:42 pm

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Tue 9/22

11:54 am-3:24 pm

Nonstop2h 30m

$250

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Fri 10/23

7:48 am-9:20 am

Nonstop2h 32m

Medellín Jose Maria Cordova Intl

Fri 10/30

8:25 pm-11:57 pm

Nonstop2h 32m

$275

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Sat 9/19

2:42 pm-4:10 pm

Nonstop2h 28m

Medellín Jose Maria Cordova Intl

Sat 9/26

10:22 am-1:52 pm

Nonstop2h 30m

$287

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Wed 9/23

8:47 am-2:15 pm

1 stop6h 28m

Medellín Jose Maria Cordova Intl

Mon 9/28

8:35 am-2:25 am

1 stop16h 50m

$298

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Tue 9/15

12:12 pm-10:50 pm

1 stop11h 38m

Medellín Jose Maria Cordova Intl

Sat 9/19

8:35 am-10:56 pm

1 stop13h 21m

$298

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Mon 8/24

6:42 pm-10:55 am

1 stop17h 13m

Medellín Jose Maria Cordova Intl

Fri 8/28

5:00 am-11:42 am

1 stop5h 42m

$298

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Sat 8/22

12:13 pm-8:15 am

1 stop21h 02m

Medellín Jose Maria Cordova Intl

Sat 8/29

8:35 am-10:56 pm

1 stop13h 21m

$298

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Fri 9/4

12:42 pm-8:15 am

1 stop20h 33m

Medellín Jose Maria Cordova Intl

Wed 9/9

5:00 am-1:13 pm

1 stop7h 13m

$298

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Tue 9/15

6:06 am-2:45 pm

1 stop9h 39m

Medellín Jose Maria Cordova Intl

Mon 9/21

12:40 pm-2:25 am

1 stop12h 45m

$298

Santo DomingoMedellín

SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl

SDQMDE

Santo Domingo Las Americas

Fri 9/4

6:41 pm-2:45 pm

1 stop21h 04m

Medellín Jose Maria Cordova Intl

Fri 9/11

5:00 am-11:42 am

1 stop5h 42m

$298

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/7

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Santo Domingo to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Medellín

What is the cheapest month to book a flight from Santo Domingo to Medellín?

Currently, February is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $243). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MDE?

Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 8, 2026.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Santo Domingo to Medellín?

Airfare is below average for this route at the moment.
Santo Domingo to Medellín flights typically cost between $256 and $323 in October.
The cheapest round-trip price found within the last 5 days was $248 on Arajet (Oct 31-Nov 7).

How often are flights from Santo Domingo to Medellín delayed?

About 15% of weekly flights between Santo Domingo and Medellín have experienced delays in the past year, with the average delay time being 156 minutes.

What is the most punctual flight time for Santo Domingo to Medellín flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Santo Domingo to Medellín flights?

Over the last year, Wingo have had the lowest number of delays on this route, with just 10% of flights being delayed.

How far ahead should I book a flight from Santo Domingo to Medellín?

The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 89 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated August 8, 2026.
See what other customers who have flown with Copa Airlines and Avianca from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,563 reviews

Crew

8.1

Comfort

7.4

Food

6.9

Boarding

7.8

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
Copa Airlines
7.6
Good
1,563 reviews
Copa Airlines
7.6
Good
1,563 reviews

Crew

8.1

Comfort

7.4

Food

6.9

Boarding

7.8

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
Avianca
6.5
Okay
2,526 reviews
Copa Airlines
7.6
Good
1,563 reviews

Crew

8.1

Comfort

7.4

Food

6.9

Boarding

7.8

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Medellín?

    For a flight from Santo Domingo to Medellín, you will be flying from Las Americas. Santo Domingo Las Americas (SDQ) is just 17.5 mi from the center of the city. Las Americas is the only Santo Domingo airport and it handles 0 outbound flights to Medellín per day. 4 airlines have flights to Medellín from Santo Domingo Las Americas on a regular basis.

  • How long is the flight from Santo Domingo to Medellín?

    Wingo, Arajet, and Copa Airlines can get you from Santo Domingo to Medellín in just under 2h 28m. Your travel time can differ by up to 4h. There are 931 mi between Santo Domingo and Medellín. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Santo Domingo to Medellín round-trip?

    Flying on Wingo is currently your cheapest option to Medellín, with prices starting at $109. Additional round-trip tickets that might be worth considering are offered by Avianca and Copa Airlines, with the lowest prices starting at $123 and $144, respectively. You may be able to fly from Santo Domingo to Medellín for 60% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Santo Domingo to Medellín one-way?

    For one-way options, check prices for Wingo. According to our data, you can fly for as low as $93. Users have also found prices from $105 and $127 on Arajet and Avianca, respectively.

  • What are the cheapest flights from Santo Domingo to Medellín?

    On average you can expect to pay $227 for a flight from Santo Domingo to Medellín. The cheapest flight overall is $121 while the most popular route, (Santo Domingo Las Americas - Medellín Jose Maria Cordova Intl) is currently priced at $250.

  • Can I find deals for flights from Santo Domingo to Medellín that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Medellín.

  • Can I find deals for business class flights from Santo Domingo to Medellín?

    Yes. Cheapflights offers flight deals from Santo Domingo to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Medellín?

    Currently, February is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $243). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $314). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Santo Domingo to Medellín

Discover the top 4 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$109Average$250FlexibilityNo cancel feeOn-time83%
AviancaCheapest$123Average$411FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$144Average$267FlexibilityNo cancel feeOn-time70%
ArajetCheapest$205Average$300FlexibilityNo cancel feeOn-timeN/A

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