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$108+ Cheap flights from Santo Domingo (SDQ) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or March, booked 68 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Santo Domingo to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2025.

Round-trip from

$226
(Wingo)

One-way from

$108
(Wingo)

Popular in

April

Cheapest in

February

Average price

$283
From Santo Domingo Las Americas to Medellín
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One-way flight from Santo Domingo Las Americas to Medellín
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santo Domingo to Medellín

Cheapest flights from Santo Domingo to Medellín
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This Wingo deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/114:22 pmSDQ - MDE
Nonstop2h 29mWingo
Thu 9/1811:58 amMDE - SDQ
Nonstop2h 34mWingo
Deal found 6/29$226
This CheapOair deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:45 amSDQ - MDE
Nonstop2h 35mArajet
Sat 9/2010:05 amMDE - SDQ
Nonstop2h 32mArajet
Deal found 7/2$231
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/245:23 amSDQ - MDE
1 stop4h 32mCopa Airlines
Thu 7/316:21 pmMDE - SDQ
1 stop7h 24mCopa Airlines
Deal found 7/1$265
This Arajet deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/223:40 amSDQ - MDE
1 stop11h 00mMultiple Airlines
Sat 9/2710:05 amMDE - SDQ
Nonstop2h 32mMultiple Airlines
Deal found 7/2$282

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.

Fly from

Santo Domingo

Fly to

Medellín

Route

Depart

Return

Price

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 9/11

4:22 pm-5:51 pm

Nonstop2h 29m

Medellín Jose Maria Cordova Intl

Thu 9/18

11:58 am-3:32 pm

Nonstop2h 34m

$226

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sun 9/14

4:25 pm-6:00 pm

Nonstop2h 35m

Medellín Jose Maria Cordova Intl

Sat 9/20

10:05 am-1:37 pm

Nonstop2h 32m

$231

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 7/24

5:23 am-8:55 am

1 stop4h 32m

Medellín Jose Maria Cordova Intl

Thu 7/31

6:21 pm-2:45 am

1 stop7h 24m

$265

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Fri 10/3

9:05 am-3:00 pm

1 stop6h 55m

Medellín Jose Maria Cordova Intl

Fri 10/10

9:27 pm-12:59 am

Nonstop2h 32m

$277

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 8/16

2:33 pm-4:01 pm

Nonstop2h 28m

$108

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Mon 8/4

9:40 am-11:15 am

Nonstop2h 35m

$120

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Mon 8/25

2:24 am-9:15 am

1 stop7h 51m

$131

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Mon 7/7

5:39 pm-8:17 am

1 stop15h 38m

$193

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Wed 7/9

6:10 pm-6:14 am

1 stop13h 04m

$206

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Thu 9/18

1:20 pm-12:25 am

2 stops12h 05m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Santo Domingo to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Medellín

How far ahead should I book a flight from Santo Domingo to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Medellín. Price data was last updated on June 27, 2025.

The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 61 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Medellín?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $378). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MDE?

Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín in the afternoon. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Santo Domingo to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Santo Domingo to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Santo Domingo to Medellín flight should consider departing on Wednesday at noon when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated July 2, 2025.
See what other customers who have flown with Copa Airlines, Avianca, and Spirit Airlines from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,465 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,465 reviews
Copa Airlines
7.5
Good
1,465 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,363 reviews
Copa Airlines
7.5
Good
1,465 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Spirit Airlines
6.3
Okay
8,103 reviews
Copa Airlines
7.5
Good
1,465 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Medellín?

    For a flight from Santo Domingo to Medellín, you will be flying from Las Americas. Santo Domingo Las Americas (SDQ) is just 17.5 mi from the center of the city. Las Americas is the only Santo Domingo airport and it handles 0 outbound flights to Medellín per day. 5 airlines have flights to Medellín from Santo Domingo Las Americas on a regular basis.

  • What are the cheapest airlines flying from Santo Domingo to Medellín round-trip?

    Flying on Wingo is currently your cheapest option to Medellín, with prices starting at $226. Additional round-trip tickets that might be worth considering are offered by Arajet and Copa Airlines, with the lowest prices starting at $231 and $265, respectively. You may be able to fly from Santo Domingo to Medellín for 14% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Santo Domingo to Medellín one-way?

    For one-way options, check prices for Wingo. According to our data, you can fly for as low as $108. Users have also found prices from $120 and $193 on Arajet and Copa Airlines, respectively.

  • What are the most reliable airlines from Santo Domingo to Medellín?

    The top 3 most reliable airlines when flying from Santo Domingo to Medellín are Euroairlines (93%), Arajet (93%) and Wingo (67%).

  • What are the cheapest flights from Santo Domingo to Medellín?

    On average you can expect to pay $236 for a flight from Santo Domingo to Medellín. The cheapest flight overall is $105 while the most popular route, (Santo Domingo Las Americas - Medellín Jose Maria Cordova Intl) is currently priced at $265.

  • Can I find deals for flights from Santo Domingo to Medellín that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Medellín.

  • Can I find deals for business class flights from Santo Domingo to Medellín?

    Yes. Cheapflights offers flight deals from Santo Domingo to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $378). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Santo Domingo to Medellín

Discover the top 5 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$145Average$262FlexibilityNo cancel feeOn-time83%
ArajetCheapest$200Average$267FlexibilityNo cancel feeOn-timeN/A
Hahn AirCheapest$221Average$376FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$244Average$268FlexibilityNo cancel feeOn-time70%
AviancaCheapest$325Average$409FlexibilityNo cancel feeOn-time71%

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