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$110+ Cheap flights from Santo Domingo (SDQ) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Jun 4 — Jun 111
Thu 6/4
Thu 6/11
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or September, booked 87 days in advance, depart on a Saturday or Thursday and return on a Tuesday

Cheap flight deals from Santo Domingo to Medellín

Cheapest flights from Santo Domingo to Medellín
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Wingo deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Tue 9/2211:54 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 5/1$216
This Wingo deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:23 am
SDQ
-
MDE
Nonstop2h 29m
Wingo
Tue 11/311:49 am
MDE
-
SDQ
Nonstop2h 34m
Wingo
Deal found 5/1$223
This Wingo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Sat 9/510:22 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 4/30$229
This Wingo deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:42 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Tue 9/2211:54 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 5/1$230
This Wingo deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:14 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Sat 9/2610:22 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 5/4$235
This Wingo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:31 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Tue 8/1811:54 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 4/30$240
This Wingo deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:14 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Sat 5/1610:22 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 4/30$243
This Wingo deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:42 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Tue 5/2611:54 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 5/1$247
This Wingo deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:42 pm
SDQ
-
MDE
Nonstop2h 28m
Wingo
Sat 5/1610:22 am
MDE
-
SDQ
Nonstop2h 30m
Wingo
Deal found 5/3$250

Find flight deals from Santo Domingo to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.

Round-trip from

$216
(Wingo)

One-way from

$110
(Wingo)

Popular in

December

Cheapest in

February

Average price

$264
From Santo Domingo Las Americas to Medellín
Search Deals
One-way flight from Santo Domingo Las Americas to Medellín
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Wed 9/16

3:55 am-12:10 pm

1 stop9h 15m

Medellín Jose Maria Cordova Intl

Sat 9/19

10:05 am-1:37 pm

Nonstop2h 32m

$271
Quickest round-trip

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 10/31

7:45 am-9:20 am

Nonstop2h 35m

Medellín Jose Maria Cordova Intl

Fri 11/6

10:00 am-1:32 pm

Nonstop2h 32m

$282

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 7/25

12:43 pm-8:15 am

1 stop20h 32m

Medellín Jose Maria Cordova Intl

Wed 7/29

9:15 am-4:15 pm

1 stop6h 00m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 10/31

8:50 am-2:44 pm

1 stop6h 54m

Medellín Jose Maria Cordova Intl

Fri 11/6

6:26 am-1:09 pm

1 stop5h 43m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Mon 9/14

12:42 pm-8:15 am

1 stop20h 33m

Medellín Jose Maria Cordova Intl

Thu 9/17

8:35 am-4:15 pm

1 stop6h 40m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Tue 6/2

6:04 am-2:45 pm

1 stop9h 41m

Medellín Jose Maria Cordova Intl

Sat 6/6

6:20 pm-2:25 am

1 stop7h 05m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 7/4

6:42 pm-8:15 am

1 stop14h 33m

Medellín Jose Maria Cordova Intl

Sat 7/11

12:40 pm-2:25 am

1 stop12h 45m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Fri 5/15

2:14 pm-9:40 am

1 stop20h 26m

Medellín Jose Maria Cordova Intl

Mon 5/18

10:35 am-2:25 am

1 stop14h 50m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Sat 5/16

8:45 am-2:15 pm

1 stop6h 30m

Medellín Jose Maria Cordova Intl

Sat 6/6

5:00 am-11:42 am

1 stop5h 42m

$288

Santo DomingoMedellín

SDQ - MDE

SDQMDE

Santo Domingo Las Americas

Wed 5/20

6:39 pm-8:15 am

1 stop14h 36m

Medellín Jose Maria Cordova Intl

Mon 5/25

4:30 pm-2:25 am

1 stop8h 55m

$288

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Santo Domingo to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Medellín

How far ahead should I book a flight from Santo Domingo to Medellín?

The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Medellín?

Currently, February is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $230). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MDE?

Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 5, 2026.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the morning.

Weekly flight availability from Santo Domingo to Medellín

Explore weekly flight availability from Santo Domingo to Medellín. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 5, 2026.

The most flights from SDQ to CO1 are scheduled on a Friday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Santo Domingo to Medellín?

How often are flights from Santo Domingo to Medellín delayed?

About 14% of weekly flights between Santo Domingo and Medellín have experienced delays in the past year, with the average delay time being 144 minutes.

What is the most punctual flight time for Santo Domingo to Medellín flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Santo Domingo to Medellín flights?

Over the last year, Wingo have had the lowest number of delays on this route, with just 9% of flights being delayed.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated May 5, 2026.
See what other customers who have flown with Copa Airlines and Avianca from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,580 reviews

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines
Copa Airlines
7.5
Good
1,580 reviews
Copa Airlines
7.5
Good
1,580 reviews

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines
Avianca
6.5
Okay
2,522 reviews
Copa Airlines
7.5
Good
1,580 reviews

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Medellín?

    For a flight from Santo Domingo to Medellín, you will be flying from Las Americas. Santo Domingo Las Americas (SDQ) is just 17.5 mi from the center of the city. Las Americas is the only Santo Domingo airport and it handles 1 outbound flight to Medellín per day. 4 airlines have flights to Medellín from Santo Domingo Las Americas on a regular basis.

  • How long is the flight from Santo Domingo to Medellín?

    Arajet and Copa Airlines can get you from Santo Domingo to Medellín in just under 2h 35m. Your travel time can differ by up to 17h 57m. There are 931 mi between Santo Domingo and Medellín. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Santo Domingo to Medellín round-trip?

    Flying on Wingo is currently your cheapest option to Medellín, with prices starting at $102. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and Avianca, with the lowest prices starting at $122 and $132, respectively. You may be able to fly from Santo Domingo to Medellín for 61% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Santo Domingo to Medellín one-way?

    For one-way options, check prices for Wingo. According to our data, you can fly for as low as $96. Users have also found prices from $101 and $127 on Arajet and Avianca, respectively.

  • What are the most reliable airlines from Santo Domingo to Medellín?

    The top 3 most reliable airlines when flying from Santo Domingo to Medellín are Arajet (82%), Euroairlines (69%) and Wingo (68%).

  • What are the cheapest flights from Santo Domingo to Medellín?

    On average you can expect to pay $210 for a flight from Santo Domingo to Medellín. The cheapest flight overall is $100 while the most popular route, (Santo Domingo Las Americas - Medellín Jose Maria Cordova Intl) is currently priced at $243.

  • Can I find deals for flights from Santo Domingo to Medellín that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Medellín.

  • Can I find deals for business class flights from Santo Domingo to Medellín?

    Yes. Cheapflights offers flight deals from Santo Domingo to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Medellín?

    Currently, February is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $230). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Santo Domingo to Cartagena flights
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Punta Cana to Cartagena flights

Top 4 airlines flying from Santo Domingo to Medellín

Discover the top 4 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$102Average$245FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$122Average$264FlexibilityNo cancel feeOn-time70%
AviancaCheapest$132Average$439FlexibilityNo cancel feeOn-time71%
ArajetCheapest$203Average$293FlexibilityNo cancel feeOn-timeN/A

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