$121+ Cheap flights from Santo Domingo (SDQ) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MDE
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Santo Domingo Las Americas to Medellín are usually found in February or May, booked 90 days in advance, depart on a Saturday or Tuesday and return on a Thursday
Cheap flight deals from Santo Domingo to Medellín
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santo Domingo to MedellínExplore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Santo Domingo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Expedia deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:10 pm -
Nonstop2h 32m
Tue 10/2710:17 am -
Nonstop2h 32m
Deal found 8/20![Arajet logo]()
$248
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm -
Nonstop2h 28m
Tue 9/2211:54 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$250
This Booking.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:05 pm -
Nonstop2h 35m
Sun 9/137:00 pm -
Nonstop2h 32m
Deal found 8/19![Arajet logo]()
$252
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:14 pm -
Nonstop2h 28m
Tue 9/2211:54 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$253
This Orbitz deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm -
Nonstop2h 35m
Thu 9/310:05 am -
Nonstop2h 32m
Deal found 8/18![Arajet logo]()
$256
This Wingo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:14 pm -
Nonstop2h 28m
Tue 10/1311:54 am -
Nonstop2h 30m
Deal found 8/17![Wingo logo]()
$257
This Booking.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:05 pm -
Nonstop2h 35m
Mon 9/218:25 pm -
Nonstop2h 32m
Deal found 8/17![Arajet logo]()
$259
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:42 pm -
Nonstop2h 28m
Sat 9/1910:22 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$260
This Booking.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:45 am -
Nonstop2h 35m
Sun 10/187:00 pm -
Nonstop2h 32m
Deal found 8/17![Arajet logo]()
$261
This Booking.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:50 am -
Nonstop2h 30m
Sat 11/2110:05 am -
Nonstop2h 32m
Deal found 8/17![Arajet logo]()
$262
This Wingo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:14 pm -
Nonstop2h 28m
Tue 9/2911:54 am -
Nonstop2h 30m
Deal found 8/21![Wingo logo]()
$264
Best flights from Santo Domingo to MedellínDiscover carefully curated flight deals from Santo Domingo to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Santo Domingo to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Wingo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:42 pm -
Nonstop2h 28m
Sat 9/1910:22 am -
Nonstop2h 30m
Deal found 8/17![Wingo logo]()
$260
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:06 am -
1 stop9h 09m
Thu 9/178:35 am -
1 stop6h 40m
Deal found 8/21![Copa Airlines logo]()
$298
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:42 pm -
Nonstop2h 28m
Sat 9/2610:22 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$273
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:42 pm -
1 stop20h 33m
Tue 9/156:20 pm -
1 stop17h 53m
Deal found 8/21![Copa Airlines logo]()
$298
This Copa Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:06 am -
1 stop9h 39m
Tue 9/85:00 am -
1 stop5h 42m
Deal found 8/16![Copa Airlines logo]()
$298
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:06 pm -
1 stop20h 39m
Thu 11/1212:40 pm -
1 stop9h 18m
Deal found 8/20![Copa Airlines logo]()
$298
This Copa Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:41 pm -
1 stop17h 14m
Wed 9/304:30 pm -
1 stop18h 11m
Deal found 8/19![Copa Airlines logo]()
$298
This Copa Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:47 am -
1 stop6h 28m
Tue 10/2712:40 pm -
1 stop9h 16m
Deal found 8/16![Copa Airlines logo]()
$298
Last-minute flights from Santo Domingo to MedellínDiscover last-minute flight deals from Santo Domingo to Medellín. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to Medellín. Data last updated August 21, 2026 and is based on user searches.
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:42 pm -
Nonstop2h 28m
Tue 8/2511:54 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$257
This Orbitz deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm -
Nonstop2h 35m
Thu 9/310:05 am -
Nonstop2h 32m
Deal found 8/18![Arajet logo]()
$256
This CheapOair deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm -
Nonstop2h 35m
Tue 9/84:27 pm -
Nonstop2h 32m
Deal found 8/17![Arajet logo]()
$266
This Wingo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm -
Nonstop2h 28m
Sat 9/510:22 am -
Nonstop2h 30m
Deal found 8/17![Wingo logo]()
$250
This Wingo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:14 pm -
Nonstop2h 28m
Tue 9/811:54 am -
Nonstop2h 30m
Deal found 8/21![Wingo logo]()
$267
This CheapOair deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:35 pm -
Nonstop2h 35m
Sun 9/137:00 pm -
Nonstop2h 32m
Deal found 8/19![Arajet logo]()
$265
This Booking.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:05 pm -
Nonstop2h 35m
Sun 9/137:00 pm -
Nonstop2h 32m
Deal found 8/19![Arajet logo]()
$252
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:14 pm -
Nonstop2h 28m
Tue 9/2211:54 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$253
This Wingo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:42 pm -
Nonstop2h 28m
Sat 9/1910:22 am -
Nonstop2h 30m
Deal found 8/18![Wingo logo]()
$260
This Booking.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:05 pm -
Nonstop2h 35m
Mon 9/218:25 pm -
Nonstop2h 32m
Deal found 8/17![Arajet logo]()
$259
This Wingo deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:14 pm -
Nonstop2h 28m
Tue 9/2911:54 am -
Nonstop2h 30m
Deal found 8/21![Wingo logo]()
$264
One-way flights from Santo Domingo to MedellínSearch for one-way flight options from Santo Domingo to Medellín. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Santo Domingo to Medellín. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This Mytrip deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:05 pm -
Nonstop2h 35m
Deal found 8/21![Arajet logo]()
$121
This Wingo deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Wingo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:42 pm -
Nonstop2h 28m
Deal found 8/19![Wingo logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm -
Nonstop2h 35m
Deal found 8/18![Arajet logo]()
$124
This Travelocity deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:05 pm -
Nonstop2h 35m
Deal found 8/18![Arajet logo]()
$125
This Mytrip deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:05 pm -
Nonstop2h 35m
Deal found 8/20![Arajet logo]()
$126
This Mytrip deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:05 pm -
Nonstop2h 35m
Deal found 8/19![Arajet logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:50 am -
Nonstop2h 30m
Deal found 8/16![Arajet logo]()
$132
This Booking.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:45 am -
Nonstop2h 35m
Deal found 8/19![Arajet logo]()
$134
This Super.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:45 pm -
1 stop6h 25m
Deal found 8/21![Avianca logo]()
$138
This Arajet deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:45 am -
Nonstop2h 35m
Deal found 8/17![Arajet logo]()
$139
This Mytrip deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:05 pm -
Nonstop2h 35m
Deal found 8/19![Arajet logo]()
$142
This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:13 pm -
1 stop21h 02m
Deal found 8/18![Copa Airlines logo]()
$143
Find flight deals from Santo Domingo to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Round-trip from | $248 (Expedia) |
|---|---|
One-way from | $122 (Wingo) |
Popular in | December |
Cheapest in | February |
Average price | $292 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Santo Domingo to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 9/12
2:42 pm-4:10 pm
Nonstop2h 28m
Medellín Jose Maria Cordova Intl
Sat 9/19
10:22 am-1:52 pm
Nonstop2h 30m
$260
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 9/19
2:42 pm-4:10 pm
Nonstop2h 28m
Medellín Jose Maria Cordova Intl
Sat 9/26
10:22 am-1:52 pm
Nonstop2h 30m
$273
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Thu 9/10
6:06 am-2:15 pm
1 stop9h 09m
Medellín Jose Maria Cordova Intl
Thu 9/17
8:35 am-4:15 pm
1 stop6h 40m
$298
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 9/12
12:42 pm-8:15 am
1 stop20h 33m
Medellín Jose Maria Cordova Intl
Tue 9/15
6:20 pm-1:13 pm
1 stop17h 53m
$298
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Thu 9/3
6:06 am-2:45 pm
1 stop9h 39m
Medellín Jose Maria Cordova Intl
Tue 9/8
5:00 am-11:42 am
1 stop5h 42m
$298
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Mon 11/9
7:06 pm-2:45 pm
1 stop20h 39m
Medellín Jose Maria Cordova Intl
Thu 11/12
12:40 pm-10:58 pm
1 stop9h 18m
$298
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 9/19
6:41 pm-10:55 am
1 stop17h 14m
Medellín Jose Maria Cordova Intl
Wed 9/30
4:30 pm-11:41 am
1 stop18h 11m
$298
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Thu 10/22
8:47 am-2:15 pm
1 stop6h 28m
Medellín Jose Maria Cordova Intl
Tue 10/27
12:40 pm-10:56 pm
1 stop9h 16m
$298
Cheapest one-way
Quickest one-way
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 8/29
2:42 pm-4:10 pm
Nonstop2h 28m
$122
Santo DomingoMedellín
SDQ Santo Domingo Las Americas - MDE Medellín Jose Maria Cordova Intl
SDQMDE
Santo Domingo Las Americas
Sat 11/28
2:43 pm-4:13 pm
Nonstop2h 30m
$122
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Santo Domingo to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Santo Domingo with our price prediction graph.
SDQ-CO1
SDQ-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santo Domingo to Medellín
SDQ-CO1
SDQ-MDE
What is the cheapest month to book a flight from Santo Domingo to Medellín?
Currently, February is the cheapest month in which you can book a flight from Santo Domingo to Medellín (average of $244). Flying from Santo Domingo to Medellín in December is currently the most expensive (average of $315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDQ to MDE?
Find hourly flight availability from Santo Domingo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 21, 2026.
A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 11% on your trip compared to booking a flight in the afternoon.
How much does it cost to fly round-trip from Santo Domingo to Medellín?
Airfare is below average for this route at the moment.
Santo Domingo to Medellín flights typically cost between $251 and $318 in January.The cheapest round-trip price found within the last 5 days was $248 on Arajet (Jan 26-Feb 2).
How often are flights from Santo Domingo to Medellín delayed?
About 16% of weekly flights between Santo Domingo and Medellín have experienced delays in the past year, with the average delay time being 155 minutes.
What is the most punctual flight time for Santo Domingo to Medellín flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santo Domingo to Medellín flights?
Over the last year, Wingo have had the lowest number of delays on this route, with just 10% of flights being delayed.
How far ahead should I book a flight from Santo Domingo to Medellín?
The price you pay for your flight from Santo Domingo to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 89 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated August 21, 2026.
See what other customers who have flown with Copa Airlines and Avianca from Santo Domingo to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Entertainment
6.8
Overall
7.6
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Boarding
7.8
Entertainment
6.8
Overall
7.6
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Boarding
7.8
Entertainment
6.8
Overall
7.6
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santo Domingo and Medellín flights
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Top 4 airlines flying from Santo Domingo to Medellín
Discover the top 4 airlines that operate flights from Santo Domingo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$110 | Average$251 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$123 | Average$433 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$144 | Average$267 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$205 | Average$301 | FlexibilityNo cancel fee | On-timeN/A |