HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medellín

$113+ Cheap flights from Key Largo, FL to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — MDE
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Key Largo to Medellín with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Key Largo to Medellín are usually found in September or October, booked 47 days in advance, depart on a Wednesday or Friday and return on a Saturday

Cheap flight deals from Key Largo to Medellín

Cheapest flights from Key Largo to Medellín
Explore the most affordable flight options available from Key Largo to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/286:35 pmMIA - MDE
Nonstop3h 40mAvianca
mié. 1/1411:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/16$259
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/275:30 amMIA - MDE
Nonstop3h 30mAvianca
mar. 12/3011:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/15$266
This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/311:00 pmMIA - MDE
1 stop6h 30mAvianca
lun. 1/1211:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/16$267
This Avianca deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:30 amMIA - MDE
Nonstop3h 30mAvianca
lun. 12/2911:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/15$268
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/275:30 amMIA - MDE
Nonstop3h 30mAvianca
lun. 12/2911:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/16$275
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/315:34 amMIA - MDE
1 stop14h 42mCopa Airlines
jue. 1/16:20 pmMDE - MIA
1 stop6h 17mCopa Airlines
Deal found 12/16$281
This Avianca deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:30 amMIA - MDE
Nonstop3h 30mAvianca
mar. 12/3011:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/16$294
This Avianca deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/265:30 amMIA - MDE
Nonstop3h 30mAvianca
mié. 1/1411:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/15$316
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/272:05 amMIA - EOH
1 stop9h 30mAvianca
mié. 1/145:15 pmEOH - MIA
1 stop9h 55mAvianca
Deal found 12/16$692
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/272:05 amMIA - EOH
1 stop9h 30mAvianca
lun. 12/298:30 amEOH - MIA
2 stops12h 45mAvianca
Deal found 12/14$697
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/277:07 amMIA - EOH
1 stop9h 33mMultiple Airlines
mar. 12/305:15 pmEOH - MIA
1 stop12h 17mMultiple Airlines
Deal found 12/15$722
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/267:07 amMIA - EOH
1 stop7h 03mMultiple Airlines
mar. 1/133:58 pmEOH - MIA
1 stop13h 32mMultiple Airlines
Deal found 12/14$727

Find flight deals from Key Largo to Medellín

Keep the following information in mind while searching for Key Largo to Medellín flight deals. Data was last updated diciembre 16, 2025.

Round-trip from

$249
(Avianca)

One-way from

$113
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$553
From Key Largo to Medellín
Search Deals
One-way flight from Key Largo to Medellín
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($57 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Key Largo to Medellín that are best for you.

Fly from

Key Largo

Fly to

Medellín

Route

Depart

Return

Price

MiamiMedellín

MIA - MDE

MIAMDE

Miami

jue. 1/8

5:30 am-9:00 am

Nonstop3h 30m

Medellín Jose Maria Cordova Intl

sáb. 1/17

11:50 pm-3:35 am

Nonstop3h 45m

$269

MiamiMedellín

MIA - MDE

MIAMDE

Miami

dom. 2/1

5:01 am-2:15 pm

1 stop9h 14m

Medellín Jose Maria Cordova Intl

dom. 2/8

9:17 am-6:56 pm

1 stop9h 39m

$271

MiamiMedellín

MIA - MDE

MIAMDE

Miami

lun. 3/2

6:35 pm-10:15 pm

Nonstop3h 40m

Medellín Jose Maria Cordova Intl

vie. 3/20

11:30 am-4:05 pm

Nonstop3h 35m

$280

MiamiMedellín

MIA - MDE

MIAMDE

Miami

mié. 2/11

5:01 am-10:56 am

1 stop5h 55m

Medellín Jose Maria Cordova Intl

sáb. 2/28

5:00 am-1:32 pm

1 stop8h 32m

$286

MiamiMedellín

MIA - MDE

MIAMDE

Miami

mié. 1/28

12:53 pm-11:30 pm

1 stop10h 37m

Medellín Jose Maria Cordova Intl

mié. 2/4

6:00 am-6:30 pm

2 stops12h 30m

$306

MiamiMedellín

MIA - MDE

MIAMDE

Miami

vie. 1/30

5:35 pm-10:05 pm

2 stops28h 30m

Medellín Jose Maria Cordova Intl

vie. 2/6

10:45 am-9:54 pm

1 stop11h 09m

$308

MiamiMedellín

MIA - MDE

MIAMDE

Miami

jue. 2/19

11:10 pm-11:30 pm

2 stops24h 20m

Medellín Jose Maria Cordova Intl

lun. 2/23

12:30 pm-10:51 am

1 stop22h 21m

$311

MiamiMedellín

MIA - MDE

MIAMDE

Miami

sáb. 2/21

4:20 pm-7:20 pm

2 stops27h 00m

Medellín Jose Maria Cordova Intl

vie. 3/6

12:30 pm-2:53 pm

1 stop26h 23m

$311

MiamiMedellín

MIA - MDE

MIAMDE

Miami

jue. 2/19

12:10 am-10:40 pm

2 stops22h 30m

Medellín Jose Maria Cordova Intl

vie. 3/6

7:40 am-2:53 pm

1 stop7h 13m

$311

MiamiMedellín

MIA - MDE

MIAMDE

Miami

jue. 2/19

11:10 pm-8:00 pm

2 stops20h 50m

Medellín Jose Maria Cordova Intl

dom. 2/22

5:30 am-2:53 pm

1 stop9h 23m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 44 results
1
2
3
...
5

Best time to book a flight from Key Largo to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Medellín

How far ahead should I book a flight from Key Largo to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Medellín. Price data was last updated on December 12, 2025.

The best time to book flights from Key Largo to Medellín is 47 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Key Largo to Medellín?

Currently, November is the cheapest month in which you can book a flight from Key Largo to Medellín (average of $138). Flying from Key Largo to Medellín in May is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to MDE?

Find hourly flight availability from Key Largo to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

It’s typically best to fly out from Key Largo to Medellín at noon. Doing so could potentially save you 16% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Key Largo to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Medellín flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Medellín

Explore weekly flight availability from Key Largo to Medellín. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated diciembre 16, 2025.

The most flights from KE9 to CO1 are scheduled on a Tuesday (10 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (6 on average).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated diciembre 16, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, LATAM Airlines, and American Airlines from Key Largo to Medellín to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Overall

7.6

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Overall

7.6

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,892 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Overall

7.6

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
American Airlines
7.2
Good
11,049 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Overall

7.6

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,485 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Overall

7.6

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Spirit Airlines
6.3
Okay
8,189 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Overall

7.6

Entertainment

6.8

Food

6.8

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key Largo to Medellín?

    For as low as $269, Avianca can have you in Medellín from Key Largo in 3h 30m. Airlines will cover a distance of 1393 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to Medellín one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $82. However, be on the lookout for offers from Avianca and JetBlue, as they are both options that can get you from Key Largo to Medellín for a low price.

  • What are the most reliable airlines from Key Largo to Medellín?

    Consider Avianca (89%), TAP AIR PORTUGAL (89%) or American Airlines (84%) when booking your flight. These represent the most reliable airlines when flying from Key Largo to Medellín.

  • What are the cheapest flights from Key Largo to Medellín?

    While on average a flight from Key Largo to Medellín is generally $699, our data shows the cheapest flight currently is $98. When looking at the most popular route, (Miami - Medellín Jose Maria Cordova Intl), you can expect to pay $260 for that flight.

  • Can I find deals for flights from Key Largo to Medellín that include hotel bookings?

    Yes. In addition to deals on Key Largo to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Medellín.

  • Can I find deals for business class flights from Key Largo to Medellín?

    Yes. Cheapflights offers flight deals from Key Largo to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Medellín?

    Currently, November is the cheapest month in which you can book a flight from Key Largo to Medellín (average of $138). Flying from Key Largo to Medellín in May is currently the most expensive (average of $213). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key Largo to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Jose Maria Cordova Intl flights
Fort Lauderdale to Jose Maria Cordova Intl flights
Miami to Bogotá flights
Orlando to Jose Maria Cordova Intl flights
Fort Lauderdale to Bogotá flights
Miami to Cartagena flights
Miami to Enrique Olaya flights
Fort Lauderdale to Cartagena flights
Fort Lauderdale to Cali flights
Miami to Cali flights
Orlando to Bogotá flights
Miami to Barranquilla flights
Tampa to Jose Maria Cordova Intl flights
Fort Lauderdale to Barranquilla flights
Orlando to Enrique Olaya flights
Fort Lauderdale to Enrique Olaya flights
Miami to Pereira flights
Orlando to Cali flights
Tampa to Bogotá flights
Orlando to Cartagena flights
Orlando to Barranquilla flights
Tampa to Cartagena flights
West Palm Beach to Jose Maria Cordova Intl flights
Fort Lauderdale to Pereira flights
Miami to Santa Marta flights
Tampa to Pereira flights
Orlando to Pereira flights
Tampa to Cali flights
West Palm Beach to Cartagena flights
Fort Lauderdale to Armenia flights
Miami to Armenia flights
West Palm Beach to Bogotá flights
Pensacola to Jose Maria Cordova Intl flights
Miami to Cúcuta flights
Jacksonville to Jose Maria Cordova Intl flights
Miami to San Andrés flights
Miami to Bucaramanga flights
Fort Lauderdale to Bucaramanga flights
Orlando to Bucaramanga flights
Tampa to Barranquilla flights
Orlando to Cúcuta flights
Jacksonville to Cartagena flights
Fort Lauderdale to Santa Marta flights
Pensacola to Bogotá flights
Jacksonville to Bogotá flights
Fort Lauderdale to San Andrés flights
Jacksonville to Cali flights
West Palm Beach to Barranquilla flights
Orlando to Armenia flights

Top 8 airlines flying from Key Largo to Medellín

Discover the top 8 airlines that operate flights from Key Largo to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$118Average$386FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$174Average$278FlexibilityNo cancel feeOn-time65%
Copa AirlinesCheapest$191Average$322FlexibilityNo cancel feeOn-time70%
AviancaCheapest$217Average$355FlexibilityNo cancel feeOn-time71%
DeltaCheapest$223Average$331FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$254Average$363FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$285Average$430FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$294Average$380FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.