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$453+ Cheap flights from Des Moines (DSM) to Luxembourg (LUX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LUX
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Des Moines to Luxembourg

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Luxembourg (LUX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$617
(Expedia)

One-way from

$453
(EaseMyTrip)
Provider with most accurate pricing for Des Moines-Luxembourg flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Luxembourg flights.
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From Des Moines to Luxembourg
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One-way flight from Des Moines to Luxembourg
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Find flight deals from Des Moines to Luxembourg

Cheapest flights from Des Moines to Luxembourg
Explore the most affordable flight options available from Des Moines to Luxembourg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:00 amDSM - LUX
3 stops18h 55mMultiple Airlines
Sun 12/212:30 pmLUX - DSM
3 stops27h 20mMultiple Airlines
Deal found 10/30$1,012
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:00 pmDSM - LUX
2 stops16h 15mMultiple Airlines
Sat 12/206:35 pmLUX - DSM
2 stops29h 06mMultiple Airlines
Deal found 10/29$1,155
This Flightnetwork deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:50 pmDSM - LUX
2 stops44h 10mLufthansa
Sun 12/212:30 pmLUX - DSM
2 stops34h 35mLufthansa
Deal found 10/30$1,233
This Expedia deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:20 amDSM - LUX
2 stops20h 30mAir France
Sun 12/216:35 pmLUX - DSM
2 stops29h 40mAir France
Deal found 10/30$1,246
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:15 pmDSM - LUX
2 stops16h 05mUnited Airlines
Sat 12/209:30 amLUX - DSM
2 stops19h 10mUnited Airlines
Deal found 10/29$1,348
This Gotogate deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:50 pmDSM - LUX
2 stops40h 10mLufthansa
Sat 12/2010:55 amLUX - DSM
2 stops41h 45mLufthansa
Deal found 10/29$1,355

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Des Moines

Fly to

Luxembourg

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 3/27

6:45 pm-10:00 pm

2 stops21h 15m

Luxembourg

Tue 3/31

6:10 am-9:36 pm

2 stops22h 26m

$648

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 12/14

8:00 am-9:55 am

3 stops18h 55m

Luxembourg

Sun 12/21

2:30 pm-10:50 am

3 stops27h 20m

$1,012

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 12/13

3:00 pm-2:15 pm

2 stops16h 15m

Luxembourg

Sat 12/20

6:35 pm-4:41 pm

2 stops29h 06m

$1,155

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 12/14

6:50 pm-10:00 pm

2 stops44h 10m

Luxembourg

Sun 12/21

2:30 pm-6:05 pm

2 stops34h 35m

$1,233

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 12/14

10:20 am-1:50 pm

2 stops20h 30m

Luxembourg

Sun 12/21

6:35 pm-5:15 pm

2 stops29h 40m

$1,246

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 12/13

5:15 pm-4:20 pm

2 stops16h 05m

Luxembourg

Sat 12/20

9:30 am-9:40 pm

2 stops19h 10m

$1,348

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 12/13

6:50 pm-6:00 pm

2 stops40h 10m

Luxembourg

Sat 12/20

10:55 am-9:40 pm

2 stops41h 45m

$1,355

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 12/13

8:00 am-10:00 am

3 stops19h 00m

$453

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 12/13

8:00 am-4:20 pm

2 stops25h 20m

$524

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 12/14

3:17 pm-4:20 pm

2 stops18h 03m

$579

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 11 results
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Compare providers for flights from Des Moines to Luxembourg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Luxembourg in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Luxembourg flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Luxembourg flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Luxembourg flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Luxembourg flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Luxembourg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Luxembourg

Have a flexible travel schedule? Discover the best time to fly to Luxembourg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Luxembourg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Luxembourg?

    A quick flight from Des Moines to Luxembourg can take about 21h 15m. Lufthansa provides one of the quickest options available for as low as $648. The distance from Des Moines to Luxembourg is about 4490 mi.

  • Can I find deals for flights from Des Moines to Luxembourg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Luxembourg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Luxembourg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Luxembourg.

  • Can I find deals for business class flights from Des Moines to Luxembourg?

    Yes. Cheapflights offers flight deals from Des Moines to Luxembourg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette

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