HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Luxembourg

$468+ Cheap flights from Des Moines (DSM) to Luxembourg (LUX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LUX
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Luxembourg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Luxembourg

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Luxembourg (LUX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$563
(American Airlines)

One-way from

$468
(Air France)
From Des Moines to Luxembourg
Search Deals
One-way flight from Des Moines to Luxembourg
Search Deals

Find flight deals from Des Moines to Luxembourg

Cheapest flights from Des Moines to Luxembourg
Explore the most affordable flight options available from Des Moines to Luxembourg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/273:48 pmDSM - LUX
2 stops23h 17mAmerican Airlines
lun. 11/39:55 pmLUX - DSM
2 stops27h 15mAmerican Airlines
Deal found 9/11$563
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/262:13 pmDSM - LUX
2 stops18h 02mDelta
dom. 11/25:00 amLUX - DSM
2 stops22h 03mDelta
Deal found 9/11$721
This lastminute.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/255:15 pmDSM - LUX
2 stops35h 20mMultiple Airlines
sáb. 11/12:45 pmLUX - DSM
2 stops36h 50mMultiple Airlines
Deal found 9/10$792
This Flightnetwork deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/268:02 amDSM - LUX
3 stops19h 53mAir Canada
dom. 11/27:10 amLUX - DSM
3 stops34h 20mAir Canada
Deal found 9/11$1,094
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/266:07 pmDSM - LUX
2 stops20h 58mAmerican Airlines
dom. 11/26:15 pmLUX - DSM
3 stops30h 55mAmerican Airlines
Deal found 9/11$1,170
This Scandinavian Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/272:13 pmDSM - LUX
2 stops26h 27mScandinavian Airlines
lun. 11/37:50 amLUX - DSM
3 stops21h 40mScandinavian Airlines
Deal found 9/11$6,510

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Des Moines

Fly to

Luxembourg

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

lun. 10/27

3:48 pm-9:05 pm

2 stops23h 17m

Luxembourg

lun. 11/3

9:55 pm-6:10 pm

2 stops27h 15m

$563

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

dom. 10/26

2:13 pm-2:15 pm

2 stops18h 02m

Luxembourg

dom. 11/2

5:00 am-9:03 pm

2 stops22h 03m

$721

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

sáb. 10/25

5:15 pm-11:35 am

2 stops35h 20m

Luxembourg

sáb. 11/1

2:45 pm-9:35 pm

2 stops36h 50m

$792

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

dom. 10/26

8:02 am-9:55 am

3 stops19h 53m

Luxembourg

dom. 11/2

7:10 am-11:30 am

3 stops34h 20m

$1,094

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

dom. 10/26

6:07 pm-9:05 pm

2 stops20h 58m

Luxembourg

dom. 11/2

6:15 pm-6:10 pm

3 stops30h 55m

$1,170

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

lun. 10/27

2:13 pm-10:40 pm

2 stops26h 27m

Luxembourg

lun. 11/3

7:50 am-10:30 pm

3 stops21h 40m

$6,510

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

dom. 10/26

2:13 pm-10:35 am

2 stops14h 22m

$468

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

dom. 10/26

8:02 am-9:55 am

3 stops19h 53m

$995

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Des Moines to Luxembourg

Have a flexible travel schedule? Discover the best time to fly to Luxembourg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Luxembourg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Luxembourg?

    A quick flight from Des Moines to Luxembourg can take about 18h 02m. American Airlines provides one of the quickest options available for as low as $721. The distance from Des Moines to Luxembourg is about 4490 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Des Moines to Luxembourg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Luxembourg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Luxembourg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Luxembourg.

  • Can I find deals for business class flights from Des Moines to Luxembourg?

    Yes. Cheapflights offers flight deals from Des Moines to Luxembourg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Luxembourg?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Luxembourg (average of $638). Flying from Des Moines to Luxembourg in June is currently the most expensive (average of $1,172). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Luxembourg

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Luxembourg flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.