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$405+ Cheap flights from Des Moines (DSM) to Luxembourg (LUX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LUX
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Des Moines to Luxembourg

Best flights from Des Moines to Luxembourg
Discover carefully curated flight deals from Des Moines to Luxembourg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 16, 2025.

This Billigflug deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/273:35 pmDSM - LUX
2 stops17h 45mMultiple Airlines
Tue 2/310:35 amLUX - DSM
2 stops18h 55mMultiple Airlines
Deal found 12/12$459
This lastminute.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/276:48 pmDSM - LUX
2 stops14h 32mLufthansa
Tue 2/310:35 amLUX - DSM
2 stops18h 15mLufthansa
Deal found 12/13$476
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/274:25 pmDSM - LUX
2 stops21h 45mAmerican Airlines
Tue 2/310:15 amLUX - DSM
3 stops19h 53mAmerican Airlines
Deal found 12/13$493
This Billigflug deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2911:30 amDSM - LUX
2 stops19h 25mMultiple Airlines
Thu 2/510:50 amLUX - DSM
2 stops18h 00mMultiple Airlines
Deal found 12/15$471
This Flightnetwork deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:48 pmDSM - LUX
2 stops14h 32mLufthansa
Thu 2/510:50 amLUX - DSM
2 stops18h 00mLufthansa
Deal found 12/14$479
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/294:00 pmDSM - LUX
2 stops22h 10mAmerican Airlines
Thu 2/511:00 amLUX - DSM
3 stops19h 08mAmerican Airlines
Deal found 12/15$494
This Air France deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2812:25 pmDSM - LUX
2 stops18h 25mMultiple Airlines
Wed 2/46:00 amLUX - DSM
2 stops21h 54mMultiple Airlines
Deal found 12/14$479

Find flight deals from Des Moines to Luxembourg

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Luxembourg (LUX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$459
(lol.travel)

One-way from

$405
(Gotogate)
Provider with most accurate pricing for Des Moines-Luxembourg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Luxembourg flights.
Search Deals
From Des Moines to Luxembourg
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One-way flight from Des Moines to Luxembourg
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Des Moines

Fly to

Luxembourg

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 1/27

3:35 pm-4:20 pm

2 stops17h 45m

Luxembourg

Tue 2/3

10:35 am-10:30 pm

2 stops18h 55m

$459

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 1/29

11:30 am-1:55 pm

2 stops19h 25m

Luxembourg

Thu 2/5

10:50 am-9:50 pm

2 stops18h 00m

$471

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 1/27

6:48 pm-4:20 pm

2 stops14h 32m

Luxembourg

Tue 2/3

10:35 am-9:50 pm

2 stops18h 15m

$476

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 1/29

6:48 pm-4:20 pm

2 stops14h 32m

Luxembourg

Thu 2/5

10:50 am-9:50 pm

2 stops18h 00m

$479

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Wed 1/28

12:25 pm-1:50 pm

2 stops18h 25m

Luxembourg

Wed 2/4

6:00 am-8:54 pm

2 stops21h 54m

$479

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 1/27

4:25 pm-9:10 pm

2 stops21h 45m

Luxembourg

Tue 2/3

10:15 am-11:08 pm

3 stops19h 53m

$493

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 1/29

4:00 pm-9:10 pm

2 stops22h 10m

Luxembourg

Thu 2/5

11:00 am-11:08 pm

3 stops19h 08m

$494

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Wed 1/28

6:48 pm-4:20 pm

2 stops14h 32m

$405

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Wed 1/28

8:00 am-10:05 am

3 stops19h 05m

$587

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Compare providers for flights from Des Moines to Luxembourg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Luxembourg in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Luxembourg flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Luxembourg flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Luxembourg flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Luxembourg flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Luxembourg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Luxembourg

Have a flexible travel schedule? Discover the best time to fly to Luxembourg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Luxembourg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Luxembourg?

    A quick flight from Des Moines to Luxembourg can take about 14h 32m. Lufthansa provides one of the quickest options available for as low as $476. The distance from Des Moines to Luxembourg is about 4490 mi.

  • Can I find deals for flights from Des Moines to Luxembourg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Luxembourg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Luxembourg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Luxembourg.

  • Can I find deals for business class flights from Des Moines to Luxembourg?

    Yes. Cheapflights offers flight deals from Des Moines to Luxembourg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette

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