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Lucerne

$396+ Cheap flights from Knoxville (TYS) to Lucerne, Switzerland

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ZRH
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Knoxville to Lucerne

Cheapest flights from Knoxville to Lucerne
Explore the most affordable flight options available from Knoxville to Lucerne. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Thrive Travel deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:40 pmTYS - ZRH
2 stops14h 05mMultiple Airlines
Mon 12/226:45 amZRH - TYS
2 stops23h 53mMultiple Airlines
Deal found 12/14$4,265
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:25 pmTYS - ZRH
2 stops30h 30mUnited Airlines
Mon 12/2211:45 amZRH - TYS
1 stop18h 14mUnited Airlines
Deal found 12/14$9,478
This Air Canada deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:40 amTYS - ZRH
3 stops20h 15mAir Canada
Mon 12/2210:15 amZRH - TYS
3 stops19h 44mAir Canada
Deal found 12/14$9,761

Find flight deals from Knoxville to Lucerne

Keep the following information in mind while searching for Knoxville to Lucerne flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$484
(United Airlines)

One-way from

$396
(Expedia)

Popular in

June

Cheapest in

November

Average price

$1,309
Provider with most accurate pricing for Knoxville McGhee Tyson-Zurich flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Zurich flights.
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From Knoxville McGhee Tyson to Lucerne
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One-way flight from Knoxville McGhee Tyson to Lucerne
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Highest demand for flights based on searches. 19% potential increase in price ($248 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Lucerne that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Knoxville to Lucerne that are best for you.

Fly from

Knoxville

Fly to

Lucerne

Route

Depart

Return

Price

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Fri 1/16

7:20 pm-4:45 pm

2 stops15h 25m

Zurich

Tue 1/20

1:00 pm-1:24 pm

2 stops30h 24m

$484

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Wed 1/28

11:40 am-11:55 am

2 stops18h 15m

Zurich

Wed 2/4

1:20 pm-8:52 pm

2 stops37h 32m

$484

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Thu 1/22

9:30 am-7:40 am

1 stop16h 10m

Zurich

Fri 1/30

1:20 pm-8:52 pm

2 stops37h 32m

$487

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Sun 1/11

7:20 pm-7:40 am

1 stop30h 20m

Zurich

Sun 1/18

11:45 am-10:57 am

1 stop29h 12m

$504

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Thu 3/12

9:40 am-10:35 am

1 stop19h 55m

Zurich

Mon 3/16

10:45 am-2:50 pm

1 stop33h 05m

$504

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Sat 2/14

1:55 pm-10:25 am

2 stops38h 30m

$396

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Sat 2/14

7:25 pm-7:40 am

1 stop30h 15m

$411

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Sat 2/14

2:54 pm-7:30 pm

3 stops46h 36m

$432

KnoxvilleZurich

TYS - ZRH

TYSZRH

Knoxville McGhee Tyson

Sat 2/14

2:21 pm-7:40 am

4 stops35h 19m

$1,695

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Best time to book a flight from Knoxville to Lucerne

Have a flexible travel schedule? Discover the best time to fly to Lucerne from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Lucerne

What is the cheapest month to book a flight from Knoxville to Lucerne?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Lucerne (average of $489). Flying from Knoxville to Lucerne in June is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to LU9?

Find hourly flight availability from Knoxville to Lucerne. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

It’s typically best to fly out from Knoxville to Lucerne in the afternoon. Doing so could potentially save you 17% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Knoxville to Lucerne?

Reviews of airlines servicing Lucerne

Get insights into the airlines that provide service to Lucerne. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lucerne. Reviews last updated December 15, 2025.
Read through reviews of airlines operating flights from Knoxville to Lucerne, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,052 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Lucerne. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Lucerne?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Lucerne. You should not have trouble finding flights to Lucerne from McGhee Tyson; the airport handles an average of 0 outbound flights to Lucerne per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Knoxville airport to Lucerne. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Lucerne?

    United Airlines can get you from Knoxville to Lucerne in just under 15h 25m. Your travel time can differ by up to . Knoxville and Lucerne are separated by a distance of 4557 mi.

  • Can I find deals for flights from Knoxville to Lucerne that include hotel bookings?

    Yes. In addition to deals on Knoxville to Lucerne flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Lucerne?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Lucerne.

  • Can I find deals for business class flights from Knoxville to Lucerne?

    Yes. Cheapflights offers flight deals from Knoxville to Lucerne by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Lucerne?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Lucerne (average of $489). Flying from Knoxville to Lucerne in June is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Lucerne

Discover the top 3 airlines that operate flights from Knoxville to Lucerne. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$609Average$1,147FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$669Average$1,177FlexibilityNo cancel feeOn-time69%
DeltaCheapest$830Average$1,237FlexibilityNo cancel feeOn-timeN/A

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