$129+ Cheap flights from Missouri to Louisville (SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Aug 29 — Sep 51
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to LouisvilleExplore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:30 am
STL
- SDF
1 stop3h 50m
Southwest
Wed 8/198:45 am
SDF
- STL
1 stop3h 35m
Southwest
Deal found 7/27![Southwest logo]()
$261
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:55 am
STL
- SDF
2 stops8h 20m
Southwest
Thu 8/2711:50 am
SDF
- STL
2 stops8h 15m
Southwest
Deal found 7/27![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:20 pm
SGF
- SDF
1 stop5h 50m
Delta
Mon 8/245:50 pm
SDF
- SGF
1 stop5h 31m
Delta
Deal found 7/27![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:39 pm
STL
- SDF
1 stop5h 29m
Delta
Thu 9/36:00 am
SDF
- STL
1 stop4h 20m
Delta
Deal found 7/28![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:05 pm
SGF
- SDF
1 stop6h 10m
United Airlines
Mon 8/175:45 pm
SDF
- SGF
1 stop6h 34m
United Airlines
Deal found 7/27![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:07 am
MCI
- SDF
1 stop6h 11m
Delta
Sat 8/2211:17 am
SDF
- MCI
1 stop7h 21m
Delta
Deal found 7/29![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:50 am
STL
- SDF
2 stops9h 30m
Southwest
Tue 9/221:15 pm
SDF
- STL
2 stops6h 45m
Southwest
Deal found 7/29![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:19 pm
SGF
- SDF
1 stop5h 40m
Delta
Sun 9/201:15 pm
SDF
- SGF
1 stop4h 39m
Delta
Deal found 7/29![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:10 am
MCI
- SDF
1 stop4h 15m
Southwest
Sat 8/226:45 am
SDF
- MCI
2 stops8h 05m
Southwest
Deal found 7/28![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:20 am
MCI
- SDF
2 stops5h 55m
Southwest
Sat 8/296:45 am
SDF
- MCI
2 stops8h 05m
Southwest
Deal found 7/27![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:00 pm
SGF
- SDF
1 stop7h 05m
Delta
Sat 11/281:01 pm
SDF
- SGF
1 stop4h 51m
Delta
Deal found 7/28![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:59 pm
STL
- SDF
1 stop5h 08m
United Airlines
Sun 8/305:10 am
SDF
- STL
1 stop6h 02m
United Airlines
Deal found 7/27![United Airlines logo]()
$328
Best flights from Missouri to LouisvilleDiscover carefully curated flight deals from Missouri to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from Missouri to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:05 pm
STL
- SDF
1 stop5h 01m
United Airlines
Sat 8/299:00 am
SDF
- STL
1 stop6h 57m
United Airlines
Deal found 7/25![United Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:20 pm
STL
- SDF
1 stop5h 05m
Southwest
Mon 8/316:00 pm
SDF
- STL
1 stop5h 25m
Southwest
Deal found 7/27![Southwest logo]()
$261
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:20 pm
SGF
- SDF
1 stop5h 50m
Delta
Mon 8/245:50 pm
SDF
- SGF
1 stop5h 31m
Delta
Deal found 7/27![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:45 am
STL
- SDF
1 stop3h 25m
Southwest
Tue 9/2210:50 am
SDF
- STL
2 stops8h 05m
Southwest
Deal found 7/29![Southwest logo]()
$266
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:45 pm
STL
- SDF
1 stop4h 50m
Southwest
Wed 8/191:15 pm
SDF
- STL
2 stops7h 45m
Southwest
Deal found 7/27![Southwest logo]()
$266
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:25 am
SGF
- SDF
1 stop5h 42m
United Airlines
Tue 9/15:45 pm
SDF
- SGF
1 stop6h 34m
United Airlines
Deal found 7/27![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:39 pm
STL
- SDF
1 stop5h 29m
Delta
Thu 9/36:00 am
SDF
- STL
1 stop4h 20m
Delta
Deal found 7/28![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:50 pm
STL
- SDF
2 stops6h 45m
Southwest
Thu 8/276:00 pm
SDF
- STL
1 stop5h 25m
Southwest
Deal found 7/27![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:25 am
MCI
- SDF
1 stop5h 35m
Delta
Sat 8/291:21 pm
SDF
- MCI
1 stop5h 17m
Delta
Deal found 7/27![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:15 pm
STL
- SDF
2 stops6h 50m
Southwest
Sat 8/299:00 am
SDF
- STL
1 stop3h 05m
Southwest
Deal found 7/25![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:19 pm
SGF
- SDF
1 stop5h 40m
Delta
Sun 9/201:15 pm
SDF
- SGF
1 stop4h 39m
Delta
Deal found 7/29![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:45 pm
STL
- SDF
1 stop3h 50m
Southwest
Tue 9/11:15 pm
SDF
- STL
2 stops7h 45m
Southwest
Deal found 7/26![Southwest logo]()
$266
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:02 am
JLN
- SDF
1 stop4h 58m
United Airlines
Sat 12/57:30 am
SDF
- JLN
1 stop5h 49m
United Airlines
Deal found 7/25![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:58 pm
SGF
- SDF
1 stop4h 36m
Delta
Sat 8/155:59 pm
SDF
- SGF
1 stop4h 20m
Delta
Deal found 7/27![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:30 am
SGF
- SDF
1 stop7h 59m
United Airlines
Sat 8/229:00 am
SDF
- SGF
1 stop6h 28m
United Airlines
Deal found 7/25![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:37 pm
SGF
- SDF
1 stop4h 22m
United Airlines
Sat 8/297:25 am
SDF
- SGF
1 stop7h 51m
United Airlines
Deal found 7/27![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:40 pm
MCI
- SDF
1 stop5h 16m
Delta
Mon 9/711:17 am
SDF
- MCI
1 stop5h 56m
Delta
Deal found 7/26![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:45 am
MCI
- SDF
1 stop6h 12m
United Airlines
Thu 10/297:00 am
SDF
- MCI
1 stop6h 23m
United Airlines
Deal found 7/29![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:35 pm
MCI
- SDF
1 stop4h 55m
Southwest
Fri 9/1810:40 am
SDF
- MCI
1 stop5h 25m
Southwest
Deal found 7/28![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:43 am
MCI
- SDF
1 stop5h 38m
Delta
Sun 8/307:54 pm
SDF
- MCI
1 stop4h 33m
Delta
Deal found 7/25![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am
MCI
- SDF
1 stop4h 41m
United Airlines
Tue 9/86:10 pm
SDF
- MCI
1 stop6h 49m
United Airlines
Deal found 7/27![United Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:15 pm
MCI
- SDF
2 stops7h 15m
Southwest
Sat 8/226:45 am
SDF
- MCI
2 stops8h 05m
Southwest
Deal found 7/28![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:00 am
JLN
- SDF
1 stop5h 35m
United Airlines
Sat 11/287:00 am
SDF
- JLN
1 stop6h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:55 am
MCI
- SDF
2 stops7h 40m
Southwest
Sun 8/305:50 pm
SDF
- MCI
1 stop5h 50m
Southwest
Deal found 7/25![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:25 am
MCI
- SDF
1 stop6h 35m
Southwest
Sun 10/185:50 am
SDF
- MCI
1 stop5h 15m
Southwest
Deal found 7/25![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:24 am
JLN
- SDF
1 stop6h 11m
United Airlines
Sat 11/79:02 am
SDF
- JLN
1 stop4h 35m
United Airlines
Deal found 7/26![United Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:37 pm
SGF
- SDF
2 stops23h 38m
United Airlines
Sun 9/67:25 am
SDF
- SGF
1 stop7h 51m
United Airlines
Deal found 7/28![United Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:37 pm
SGF
- SDF
1 stop7h 54m
United Airlines
Mon 8/311:56 pm
SDF
- SGF
2 stops10h 23m
United Airlines
Deal found 7/27![United Airlines logo]()
$663
Last-minute flights from Missouri to LouisvilleDiscover last-minute flight deals from Missouri to Louisville. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Louisville. Data last updated July 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:58 pm
SGF
- SDF
1 stop4h 36m
Delta
Sat 8/155:59 pm
SDF
- SGF
1 stop4h 20m
Delta
Deal found 7/27![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:05 pm
SGF
- SDF
1 stop6h 10m
United Airlines
Mon 8/175:45 pm
SDF
- SGF
1 stop6h 34m
United Airlines
Deal found 7/27![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:30 am
STL
- SDF
1 stop3h 50m
Southwest
Wed 8/198:45 am
SDF
- STL
1 stop3h 35m
Southwest
Deal found 7/27![Southwest logo]()
$261
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:07 am
MCI
- SDF
1 stop6h 11m
Delta
Sat 8/2211:17 am
SDF
- MCI
1 stop7h 21m
Delta
Deal found 7/29![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:10 am
MCI
- SDF
1 stop4h 15m
Southwest
Sat 8/226:45 am
SDF
- MCI
2 stops8h 05m
Southwest
Deal found 7/28![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:20 pm
SGF
- SDF
1 stop5h 50m
Delta
Mon 8/245:50 pm
SDF
- SGF
1 stop5h 31m
Delta
Deal found 7/27![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:55 am
STL
- SDF
2 stops8h 20m
Southwest
Thu 8/2711:50 am
SDF
- STL
2 stops8h 15m
Southwest
Deal found 7/27![Southwest logo]()
$290
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:20 am
MCI
- SDF
2 stops5h 55m
Southwest
Sat 8/296:45 am
SDF
- MCI
2 stops8h 05m
Southwest
Deal found 7/27![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:59 pm
STL
- SDF
1 stop5h 08m
United Airlines
Sun 8/305:10 am
SDF
- STL
1 stop6h 02m
United Airlines
Deal found 7/27![United Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:50 pm
STL
- SDF
2 stops6h 45m
Southwest
Sun 8/304:05 pm
SDF
- STL
1 stop6h 00m
Southwest
Deal found 7/27![Southwest logo]()
$333
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:39 pm
STL
- SDF
1 stop5h 29m
Delta
Thu 9/36:00 am
SDF
- STL
1 stop4h 20m
Delta
Deal found 7/28![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:32 am
STL
- SDF
2 stops10h 59m
American Airlines
Thu 9/36:30 pm
SDF
- STL
1 stop6h 44m
American Airlines
Deal found 7/28![American Airlines logo]()
$340
One-way flights from Missouri to LouisvilleSearch for one-way flight options from Missouri to Louisville. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from Missouri to Louisville. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:23 am
SGF
- SDF
1 stop29h 06m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$129
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:45 am
STL
- SDF
1 stop4h 55m
Southwest
Deal found 7/28![Southwest logo]()
$131
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:05 am
STL
- SDF
2 stops8h 25m
Southwest
Deal found 7/28![Southwest logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:17 pm
STL
- SDF
2 stops15h 12m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:04 pm
SGF
- SDF
1 stop23h 36m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:47 pm
SGF
- SDF
1 stop21h 46m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:44 am
SGF
- SDF
1 stop6h 00m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$154
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:45 pm
MCI
- SDF
1 stop3h 40m
Southwest
Deal found 7/28![Southwest logo]()
$158
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:00 am
MCI
- SDF
1 stop4h 35m
American Airlines
Deal found 7/26![American Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:04 pm
SGF
- SDF
1 stop17h 24m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:59 pm
SGF
- SDF
1 stop20h 59m
Allegiant Air
Deal found 7/28![Allegiant Air logo]()
$176
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:10 am
MCI
- SDF
2 stops10h 55m
Southwest
Deal found 7/28![Southwest logo]()
$195
Find flight deals from Missouri to Louisville
Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated July 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (Southwest) |
One-way from | $129 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Sat 8/22
1:05 pm-7:06 pm
1 stop5h 01m
Louisville Intl
Sat 8/29
9:00 am-2:57 pm
1 stop6h 57m
$261
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Mon 8/24
2:20 pm-8:25 pm
1 stop5h 05m
Louisville Intl
Mon 8/31
6:00 pm-10:25 pm
1 stop5h 25m
$261
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Sat 9/19
5:45 am-10:10 am
1 stop3h 25m
Louisville Intl
Tue 9/22
10:50 am-5:55 pm
2 stops8h 05m
$266
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Tue 8/18
2:45 pm-8:35 pm
1 stop4h 50m
Louisville Intl
Wed 8/19
1:15 pm-8:00 pm
2 stops7h 45m
$266
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Tue 8/25
12:50 pm-8:35 pm
2 stops6h 45m
Louisville Intl
Thu 8/27
6:00 pm-10:25 pm
1 stop5h 25m
$266
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Sat 8/22
1:15 pm-9:05 pm
2 stops6h 50m
Louisville Intl
Sat 8/29
9:00 am-11:05 am
1 stop3h 05m
$266
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Wed 8/26
3:45 pm-8:35 pm
1 stop3h 50m
Louisville Intl
Tue 9/1
1:15 pm-8:00 pm
2 stops7h 45m
$266
SpringfieldLouisville
SGF - SDF
SGFSDF
Springfield-Branson
Fri 8/21
3:20 pm-10:10 pm
1 stop5h 50m
Louisville Intl
Mon 8/24
5:50 pm-10:21 pm
1 stop5h 31m
$299
SpringfieldLouisville
SGF - SDF
SGFSDF
Springfield-Branson
Tue 8/25
6:25 am-1:07 pm
1 stop5h 42m
Louisville Intl
Tue 9/1
5:45 pm-11:19 pm
1 stop6h 34m
$299
St. LouisLouisville
STL - SDF
STLSDF
Lambert-St Louis
Fri 8/28
3:39 pm-10:08 pm
1 stop5h 29m
Louisville Intl
Thu 9/3
6:00 am-9:20 am
1 stop4h 20m
$307
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from Missouri to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
STL-SDF
SGF-SDF
MCI-SDF
JLN-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Louisville
USMO-SDF
STL-SDF
SGF-SDF
MCI-SDF
JLN-SDF
What is the cheapest month to book a flight from Missouri to Louisville?
Currently, August is the cheapest month in which you can book a flight from Missouri to Louisville (average of $256). Flying from Missouri to Louisville in May is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsCorydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Louisville flight routes
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Alternative routes for Missouri to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Louisville by cabin class
Find flights from Missouri to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 30, 2026.
Missouri and Louisville flights
Browse other Missouri and Louisville flight options. Last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Louisville flights
Consider these flights traveling from Missouri to Louisville.
Top 3 airlines flying from Missouri to Louisville
Discover the top 3 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$329 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$296 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$245 | Average$444 | FlexibilityNo cancel fee | On-time63% |