$157+ Cheap flights from Missouri to Louisville (SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Dec 5 — Dec 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to LouisvilleExplore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:02 am -
1 stop14h 35m
Wed 12/910:13 am -
1 stop13h 04m
Deal found 11/2![American Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:25 am -
1 stop5h 52m
Thu 12/107:10 am -
1 stop4h 25m
Deal found 11/3![United Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/263:10 pm -
1 stop6h 29m
Fri 1/16:00 pm -
1 stop6h 27m
Deal found 11/3![United Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:56 pm -
1 stop6h 03m
Sat 12/196:00 pm -
1 stop4h 46m
Deal found 11/3![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:25 am -
1 stop5h 50m
Wed 12/97:20 am -
2 stops7h 25m
Deal found 11/2![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
1 stop3h 10m
Sun 12/133:45 pm -
1 stop8h 20m
Deal found 11/4![Southwest logo]()
$343
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:34 am -
1 stop6h 55m
Sun 12/1310:13 am -
1 stop7h 21m
Deal found 11/2![Delta logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:49 pm -
2 stops46h 43m
Mon 12/219:56 am -
1 stop9h 02m
Deal found 11/4![Multiple Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
1 stop3h 10m
Sat 12/1212:15 pm -
2 stops8h 45m
Deal found 11/4![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:20 pm -
2 stops7h 15m
Fri 12/181:05 pm -
1 stop5h 15m
Deal found 11/3![Southwest logo]()
$348
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:10 pm -
1 stop4h 42m
Sat 11/215:57 pm -
1 stop4h 44m
Deal found 11/2![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:00 am -
1 stop4h 24m
Sat 12/196:00 pm -
1 stop6h 27m
Deal found 11/3![United Airlines logo]()
$349
Best flights from Missouri to LouisvilleDiscover carefully curated flight deals from Missouri to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Missouri to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/511:36 am -
1 stop3h 59m
Tue 1/1210:20 am -
1 stop5h 17m
Deal found 11/3![United Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:35 am -
1 stop5h 41m
Tue 12/155:59 pm -
1 stop6h 57m
Deal found 11/4![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
1 stop3h 10m
Sat 12/1212:15 pm -
2 stops8h 45m
Deal found 11/4![Southwest logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:47 pm -
1 stop21h 30m
Mon 11/234:07 pm -
1 stop25h 48m
Deal found 11/3![Allegiant Air logo]()
$356
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
2 stops14h 40m
Tue 1/1211:03 am -
2 stops12h 57m
Deal found 10/31![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:45 am -
1 stop4h 41m
Sat 1/167:00 am -
1 stop4h 46m
Deal found 11/3![United Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop5h 00m
Sat 12/57:41 am -
1 stop6h 49m
Deal found 11/4![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:00 pm -
1 stop5h 49m
Mon 12/216:00 pm -
1 stop6h 38m
Deal found 11/3![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/113:00 pm -
2 stops6h 15m
Tue 12/1512:55 pm -
1 stop5h 50m
Deal found 11/4![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/43:30 pm -
1 stop4h 21m
Sat 5/87:00 am -
1 stop5h 11m
Deal found 11/2![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:27 am -
1 stop5h 50m
Sat 12/196:00 pm -
1 stop4h 46m
Deal found 11/4![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:20 pm -
2 stops7h 15m
Fri 12/181:05 pm -
1 stop5h 15m
Deal found 11/3![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:15 pm -
1 stop10h 40m
Sat 12/512:45 pm -
2 stops7h 05m
Deal found 11/4![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:00 am -
1 stop4h 24m
Sat 12/196:00 pm -
1 stop6h 27m
Deal found 11/3![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:00 am -
1 stop4h 04m
Sun 1/32:54 pm -
1 stop4h 14m
Deal found 11/3![American Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:10 pm -
1 stop6h 20m
Mon 11/235:10 am -
1 stop6h 26m
Deal found 11/4![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:20 pm -
2 stops7h 15m
Mon 12/215:40 am -
2 stops9h 05m
Deal found 11/3![Southwest logo]()
$408
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:35 am -
1 stop4h 38m
Thu 11/196:11 pm -
1 stop6h 47m
Deal found 10/31![American Airlines logo]()
$569
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1911:35 am -
1 stop5h 40m
Sun 2/217:17 am -
1 stop4h 43m
Deal found 11/1![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1211:25 am -
1 stop4h 14m
Fri 12/186:00 pm -
1 stop6h 27m
Deal found 11/3![United Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:05 pm -
1 stop5h 03m
Tue 11/246:24 am -
1 stop4h 40m
Deal found 11/4![American Airlines logo]()
$571
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:26 am -
2 stops10h 00m
Mon 11/231:14 pm -
1 stop5h 44m
Deal found 11/3![American Airlines logo]()
$577
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:02 am -
1 stop6h 21m
Tue 12/1510:25 am -
1 stop5h 20m
Deal found 11/1![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:30 pm -
1 stop3h 10m
Thu 11/195:40 am -
2 stops6h 20m
Deal found 10/30![Southwest logo]()
$574
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/316:37 pm -
1 stop4h 18m
Sat 4/32:20 pm -
1 stop6h 12m
Deal found 11/3![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
2 stops9h 05m
Sat 11/211:10 pm -
1 stop7h 05m
Deal found 11/2![Southwest logo]()
$574
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/511:22 am -
1 stop6h 07m
Sat 1/93:27 pm -
1 stop6h 28m
Deal found 11/1![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:45 pm -
2 stops8h 40m
Sun 11/2212:05 pm -
2 stops8h 05m
Deal found 11/2![Southwest logo]()
$579
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:55 pm -
1 stop6h 04m
Sat 12/53:20 pm -
1 stop6h 41m
Deal found 11/4![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:01 am -
1 stop6h 36m
Sat 11/285:10 am -
1 stop5h 34m
Deal found 10/31![United Airlines logo]()
$424
Last-minute flights from Missouri to LouisvilleDiscover last-minute flight deals from Missouri to Louisville. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Louisville. Data last updated November 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:10 pm -
1 stop4h 42m
Sat 11/215:57 pm -
1 stop4h 44m
Deal found 11/2![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:02 am -
1 stop14h 35m
Wed 12/910:13 am -
1 stop13h 04m
Deal found 11/2![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:25 am -
1 stop5h 50m
Wed 12/97:20 am -
2 stops7h 25m
Deal found 11/2![Southwest logo]()
$320
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:25 am -
1 stop5h 52m
Thu 12/107:10 am -
1 stop4h 25m
Deal found 11/3![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
1 stop3h 10m
Sun 12/133:45 pm -
1 stop8h 20m
Deal found 11/4![Southwest logo]()
$343
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
1 stop3h 10m
Sat 12/1212:15 pm -
2 stops8h 45m
Deal found 11/4![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:34 am -
1 stop6h 55m
Sun 12/1310:13 am -
1 stop7h 21m
Deal found 11/2![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:00 am -
1 stop4h 24m
Sat 12/196:00 pm -
1 stop6h 27m
Deal found 11/3![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:56 pm -
1 stop6h 03m
Sat 12/196:00 pm -
1 stop4h 46m
Deal found 11/3![United Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:49 pm -
2 stops46h 43m
Mon 12/219:56 am -
1 stop9h 02m
Deal found 11/4![Multiple Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:20 pm -
2 stops7h 15m
Fri 12/181:05 pm -
1 stop5h 15m
Deal found 11/3![Southwest logo]()
$348
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/263:10 pm -
1 stop6h 29m
Fri 1/16:00 pm -
1 stop6h 27m
Deal found 11/3![United Airlines logo]()
$313
One-way flights from Missouri to LouisvilleSearch for one-way flight options from Missouri to Louisville. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Missouri to Louisville. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop10h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$157
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop5h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:13 pm -
2 stops21h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$160
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:00 am -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$160
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:15 am -
2 stops6h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:00 pm -
3 stops42h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:00 pm -
3 stops18h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:29 pm -
3 stops37h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:20 pm -
2 stops6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:51 pm -
3 stops45h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:12 am -
1 stop4h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:31 pm -
1 stop3h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$285
Find flight deals from Missouri to Louisville
Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $264 (Kiwi.com) |
One-way from | $157 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisLouisville
STL Lambert-St Louis - SDF Louisville Intl
STLSDF
Lambert-St Louis
Tue 12/1
6:00 am-5:13 pm
1 stop10h 13m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$157
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Thu 12/24
4:10 pm-9:50 pm
1 stop4h 40m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$158
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Wed 11/25
6:00 am-12:00 pm
1 stop5h 00m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$158
SpringfieldLouisville
SGF Springfield-Branson - SDF Louisville Intl
SGFSDF
Springfield-Branson
Thu 12/24
5:00 am-11:04 am
1 stop5h 04m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$160
SpringfieldLouisville
SGF Springfield-Branson - SDF Louisville Intl
SGFSDF
Springfield-Branson
Wed 12/23
5:00 am-11:04 am
1 stop5h 04m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$160
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Thu 12/24
8:15 am-3:35 pm
2 stops6h 20m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$191
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Wed 11/25
8:29 pm-10:59 am
3 stops37h 30m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$235
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Wed 11/25
2:20 pm-9:25 pm
2 stops6h 05m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$264
Quickest round-trip
SpringfieldLouisville
SGF Springfield-Branson - SDF Louisville Intl
SGFSDF
Springfield-Branson
Tue 12/1
7:12 am-12:43 pm
1 stop4h 31m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$274
St. LouisLouisville
STL Lambert-St Louis - SDF Louisville Intl
STLSDF
Lambert-St Louis
Tue 12/1
6:13 pm-5:03 pm
3 stops45h 50m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$283
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Missouri to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
STL-SDF
MCI-SDF
SGF-SDF
COU-SDF
JLN-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Louisville
USMO-SDF
STL-SDF
MCI-SDF
SGF-SDF
COU-SDF
What is the cheapest month to book a flight from Missouri to Louisville?
Currently, August is the cheapest month in which you can book a flight from Missouri to Louisville (average of $296). Flying from Missouri to Louisville in May is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Missouri to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Louisville by cabin class
Find flights from Missouri to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Missouri and Louisville flights
Browse other Missouri and Louisville flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Louisville flights
Consider these flights traveling from Missouri to Louisville.
Top 4 airlines flying from Missouri to Louisville
Discover the top 4 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$245 | Average$434 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$254 | Average$404 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$274 | Average$397 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$279 | Average$329 | FlexibilityNo cancel fee | On-time71% |