$120+ Cheap flights from Missouri to Louisville (SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Oct 15 — Oct 221
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to LouisvilleExplore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:45 am -
1 stop5h 50m
Wed 10/218:35 am -
1 stop5h 55m
Deal found 9/14![Southwest logo]()
$239
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:40 pm -
1 stop5h 35m
Sat 10/243:50 pm -
1 stop6h 20m
Deal found 9/14![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:00 pm -
1 stop3h 49m
Wed 10/77:05 am -
1 stop4h 46m
Deal found 9/10![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:25 pm -
1 stop4h 34m
Wed 10/77:00 am -
1 stop4h 45m
Deal found 9/10![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:50 am -
2 stops5h 25m
Wed 10/77:10 pm -
1 stop3h 55m
Deal found 9/10![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:25 pm -
1 stop6h 34m
Wed 10/710:39 am -
1 stop7h 15m
Deal found 9/10![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:25 pm -
1 stop5h 08m
Tue 10/2011:06 am -
1 stop6h 41m
Deal found 9/13![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am -
2 stops5h 50m
Wed 10/75:45 am -
1 stop5h 20m
Deal found 9/10![Southwest logo]()
$320
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop5h 47m
Thu 10/299:02 am -
1 stop4h 08m
Deal found 9/14![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:35 am -
1 stop11h 55m
Wed 10/218:35 am -
2 stops6h 55m
Deal found 9/10![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:15 am -
1 stop5h 54m
Wed 9/307:00 am -
1 stop4h 45m
Deal found 9/10![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:31 am -
1 stop3h 52m
Sun 10/118:18 pm -
1 stop4h 41m
Deal found 9/14![American Airlines logo]()
$332
Best flights from Missouri to LouisvilleDiscover carefully curated flight deals from Missouri to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Missouri to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:45 am -
1 stop5h 50m
Wed 10/218:35 am -
1 stop5h 55m
Deal found 9/14![Southwest logo]()
$239
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:14 pm -
1 stop4h 17m
Wed 10/2110:00 am -
1 stop5h 37m
Deal found 9/10![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:40 pm -
1 stop5h 35m
Sat 10/243:50 pm -
1 stop6h 20m
Deal found 9/14![Southwest logo]()
$266
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:47 pm -
2 stops9h 08m
Wed 10/76:29 am -
1 stop4h 33m
Deal found 9/10![American Airlines logo]()
$554
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop5h 47m
Thu 10/299:02 am -
1 stop4h 08m
Deal found 9/14![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:50 am -
2 stops5h 25m
Wed 10/77:10 pm -
1 stop3h 55m
Deal found 9/10![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:15 am -
1 stop5h 54m
Wed 9/307:00 am -
1 stop4h 45m
Deal found 9/10![United Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:25 pm -
1 stop4h 34m
Wed 10/77:00 am -
1 stop4h 45m
Deal found 9/11![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:00 pm -
1 stop5h 40m
Sat 10/175:35 am -
2 stops8h 25m
Deal found 9/14![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:15 am -
1 stop5h 54m
Sat 10/39:04 am -
1 stop6h 26m
Deal found 9/14![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:40 am -
1 stop10h 15m
Sun 12/135:05 am -
1 stop8h 10m
Deal found 9/14![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops7h 55m
Wed 10/218:35 am -
2 stops6h 55m
Deal found 9/10![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/53:13 pm -
1 stop4h 19m
Sat 1/99:32 am -
1 stop5h 08m
Deal found 9/13![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:35 pm -
1 stop6h 00m
Sat 10/319:15 am -
1 stop3h 40m
Deal found 9/12![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:02 am -
1 stop7h 22m
Wed 12/910:45 am -
1 stop23h 55m
Deal found 9/10![United Airlines logo]()
$450
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:45 pm -
1 stop5h 30m
Tue 10/612:50 pm -
1 stop5h 30m
Deal found 9/13![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:35 pm -
1 stop6h 00m
Mon 10/193:30 pm -
2 stops9h 25m
Deal found 9/14![Southwest logo]()
$420
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:55 am -
1 stop5h 30m
Sun 10/115:50 am -
1 stop5h 15m
Deal found 9/14![Southwest logo]()
$425
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:20 am -
1 stop6h 51m
Wed 10/77:25 am -
1 stop7h 51m
Deal found 9/10![United Airlines logo]()
$527
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:40 pm -
2 stops8h 35m
Sun 11/154:40 pm -
2 stops7h 45m
Deal found 9/12![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:25 pm -
2 stops14h 53m
Tue 10/203:36 pm -
1 stop6h 04m
Deal found 9/13![United Airlines logo]()
$533
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:40 pm -
2 stops6h 45m
Mon 11/306:30 pm -
1 stop6h 25m
Deal found 9/13![Southwest logo]()
$429
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:05 am -
2 stops8h 20m
Mon 10/123:35 pm -
2 stops5h 20m
Deal found 9/14![Southwest logo]()
$435
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/114:35 pm -
1 stop6h 40m
Sun 10/186:30 am -
2 stops7h 30m
Deal found 9/14![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:32 am -
1 stop24h 57m
Mon 10/127:00 am -
1 stop6h 09m
Deal found 9/13![United Airlines logo]()
$705
Last-minute flights from Missouri to LouisvilleDiscover last-minute flight deals from Missouri to Louisville. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Louisville. Data last updated September 15, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:15 am -
1 stop5h 54m
Wed 9/307:00 am -
1 stop4h 45m
Deal found 9/10![United Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:25 pm -
1 stop4h 34m
Wed 10/77:00 am -
1 stop4h 45m
Deal found 9/10![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:25 pm -
1 stop6h 34m
Wed 10/710:39 am -
1 stop7h 15m
Deal found 9/10![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:00 pm -
1 stop3h 49m
Wed 10/77:05 am -
1 stop4h 46m
Deal found 9/10![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:50 am -
2 stops5h 25m
Wed 10/77:10 pm -
1 stop3h 55m
Deal found 9/10![Southwest logo]()
$302
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am -
2 stops5h 50m
Wed 10/75:45 am -
1 stop5h 20m
Deal found 9/10![Southwest logo]()
$320
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:31 am -
1 stop3h 52m
Sun 10/118:18 pm -
1 stop4h 41m
Deal found 9/14![American Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:25 pm -
1 stop5h 08m
Tue 10/2011:06 am -
1 stop6h 41m
Deal found 9/13![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:45 am -
1 stop5h 50m
Wed 10/218:35 am -
1 stop5h 55m
Deal found 9/14![Southwest logo]()
$239
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:35 am -
1 stop11h 55m
Wed 10/218:35 am -
2 stops6h 55m
Deal found 9/10![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:40 pm -
1 stop5h 35m
Sat 10/243:50 pm -
1 stop6h 20m
Deal found 9/14![Southwest logo]()
$266
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop5h 47m
Thu 10/299:02 am -
1 stop4h 08m
Deal found 9/14![United Airlines logo]()
$324
One-way flights from Missouri to LouisvilleSearch for one-way flight options from Missouri to Louisville. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Missouri to Louisville. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:04 am -
1 stop4h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$120
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:25 am -
2 stops5h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:35 pm -
2 stops38h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$127
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:31 pm -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$135
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:35 pm -
1 stop5h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$149
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop3h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$150
This KAYAK deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:39 pm -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$152
This KAYAK deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 pm -
1 stop3h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$157
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:20 am -
1 stop4h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:35 pm -
2 stops24h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$161
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
2 stops7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Southwest logo]()
$194
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:02 am -
1 stop4h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$199
Find flight deals from Missouri to Louisville
Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $239 (Southwest) |
One-way from | $120 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Wed 10/14
7:04 am-12:54 pm
1 stop4h 50m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$120
St. LouisLouisville
STL Lambert-St Louis - SDF Louisville Intl
STLSDF
Lambert-St Louis
Mon 10/26
6:35 pm-10:11 am
2 stops38h 36m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$127
St. LouisLouisville
STL Lambert-St Louis - SDF Louisville Intl
STLSDF
Lambert-St Louis
Thu 10/15
5:35 pm-11:59 pm
1 stop5h 24m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$149
St. LouisLouisville
STL Lambert-St Louis - SDF Louisville Intl
STLSDF
Lambert-St Louis
Mon 10/26
5:50 pm-10:35 pm
1 stop3h 45m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$150
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Mon 10/5
6:39 pm-11:59 pm
1 stop4h 20m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$152
Quickest round-trip
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Mon 10/5
6:00 pm-10:35 pm
1 stop3h 35m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$157
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Sat 10/3
6:20 am-11:54 am
1 stop4h 34m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$158
St. LouisLouisville
STL Lambert-St Louis - SDF Louisville Intl
STLSDF
Lambert-St Louis
Fri 10/9
6:35 pm-8:31 pm
2 stops24h 56m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$161
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Sat 10/3
6:00 am-2:55 pm
2 stops7h 55m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
Kansas CityLouisville
MCI Kansas City - SDF Louisville Intl
MCISDF
Kansas City
Thu 10/15
5:31 pm-11:59 pm
1 stop5h 28m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$203
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from Missouri to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
MCI-SDF
STL-SDF
SGF-SDF
JLN-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Louisville
USMO-SDF
MCI-SDF
STL-SDF
SGF-SDF
JLN-SDF
What is the cheapest month to book a flight from Missouri to Louisville?
Currently, November is the cheapest month in which you can book a flight from Missouri to Louisville (average of $256). Flying from Missouri to Louisville in May is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Missouri to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Louisville by cabin class
Find flights from Missouri to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Missouri and Louisville flights
Browse other Missouri and Louisville flight options. Last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Louisville flights
Consider these flights traveling from Missouri to Louisville.
Top 3 airlines flying from Missouri to Louisville
Discover the top 3 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$383 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$245 | Average$444 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$254 | Average$368 | FlexibilityNo cancel fee | On-time69% |