Louisville

$117+ Cheap flights from Missouri to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Apr 7 — Apr 141
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Cheap flight deals from Missouri to Louisville

Cheapest flights from Missouri to Louisville
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.

This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:00 am
STL
-
SDF
1 stop8h 18m
American Airlines
Wed 4/86:00 am
SDF
-
STL
1 stop11h 00m
American Airlines
Deal found 3/4$223
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:51 am
STL
-
SDF
1 stop9h 14m
American Airlines
Sat 4/1811:16 am
SDF
-
STL
1 stop6h 25m
American Airlines
Deal found 3/3$249
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 pm
STL
-
SDF
1 stop4h 45m
Southwest
Sat 4/256:40 am
SDF
-
STL
1 stop2h 45m
Southwest
Deal found 3/4$250
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:25 am
MCI
-
SDF
1 stop3h 25m
Southwest
Wed 4/85:50 pm
SDF
-
MCI
1 stop5h 50m
Southwest
Deal found 3/3$255
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:30 pm
STL
-
SDF
2 stops7h 25m
Southwest
Sat 4/186:40 am
SDF
-
STL
1 stop2h 45m
Southwest
Deal found 3/3$256
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
MCI
-
SDF
2 stops7h 40m
Southwest
Sat 4/186:40 am
SDF
-
MCI
2 stops6h 05m
Southwest
Deal found 3/3$265
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:10 am
STL
-
SDF
2 stops7h 45m
Southwest
Wed 4/88:55 am
SDF
-
STL
1 stop3h 35m
Southwest
Deal found 3/4$280
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:27 pm
STL
-
SDF
1 stop8h 03m
American Airlines
Thu 4/169:00 am
SDF
-
STL
1 stop8h 41m
American Airlines
Deal found 3/4$290
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:54 pm
STL
-
SDF
1 stop4h 31m
American Airlines
Wed 5/138:36 am
SDF
-
STL
1 stop9h 05m
American Airlines
Deal found 3/3$293
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:30 pm
SGF
-
SDF
1 stop4h 21m
Delta
Sat 11/215:45 pm
SDF
-
SGF
1 stop5h 47m
Delta
Deal found 3/4$294
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:51 am
STL
-
SDF
1 stop3h 55m
American Airlines
Sat 5/29:43 am
SDF
-
STL
1 stop4h 39m
American Airlines
Deal found 3/6$297
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:20 am
STL
-
SDF
1 stop5h 35m
Southwest
Mon 4/205:45 am
SDF
-
STL
1 stop6h 05m
Southwest
Deal found 3/4$299

Find flight deals from Missouri to Louisville

Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated March 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$223
(American Airlines)

One-way from

$117
(American Airlines)

Popular in

July

Cheapest in

April

Average price

$550
Provider with most accurate pricing for Lambert-St Louis-Louisville Intl flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Louisville Intl flights.
From Missouri to Louisville Intl
One-way flight from Missouri to Louisville Intl
Highest demand for flights based on searches. 12% potential increase in price ($69 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 5/13

5:25 am-9:50 am

1 stop3h 25m

Louisville Intl

Sat 5/16

6:40 am-9:35 am

1 stop3h 55m

$255

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 4/8

5:25 am-9:50 am

1 stop3h 25m

Louisville Intl

Wed 4/8

5:50 pm-10:40 pm

1 stop5h 50m

$255

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Wed 4/15

2:30 pm-10:55 pm

2 stops7h 25m

Louisville Intl

Sat 4/18

6:40 am-8:25 am

1 stop2h 45m

$256

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Sat 4/18

2:05 pm-8:50 pm

2 stops5h 45m

Louisville Intl

Sat 4/25

5:35 am-1:35 pm

2 stops9h 00m

$265

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Wed 4/1

6:10 am-2:55 pm

2 stops7h 45m

Louisville Intl

Wed 4/8

8:55 am-11:30 am

1 stop3h 35m

$280

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Mon 5/11

6:54 pm-12:25 am

1 stop4h 31m

Louisville Intl

Wed 5/13

8:36 am-4:41 pm

1 stop9h 05m

$293

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

Fri 3/20

6:55 pm-11:57 pm

1 stop4h 02m

Louisville Intl

Tue 3/24

7:05 am-11:08 am

1 stop5h 03m

$299

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Tue 5/12

9:14 am-8:17 pm

1 stop10h 03m

Louisville Intl

Wed 5/13

7:15 am-9:13 pm

1 stop14h 58m

$303

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Mon 5/11

5:40 am-9:55 am

1 stop3h 15m

Louisville Intl

Wed 5/13

12:10 pm-8:00 pm

2 stops8h 50m

$304

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Tue 4/14

10:25 am-3:05 pm

1 stop3h 40m

Louisville Intl

Thu 4/16

7:30 am-3:25 pm

2 stops8h 55m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/3

Showing 1-10 of 51 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Louisville

What is the cheapest month to book a flight from Missouri to Louisville?

Currently, November is the cheapest month in which you can book a flight from Missouri to Louisville (average of $146). Flying from Missouri to Louisville in January is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Louisville from Missouri?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from Missouri to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How long is the flight from Missouri to Louisville?

    For as low as $299, American Airlines can have you in Louisville from Missouri in 4h 02m. Missouri and Louisville are separated by a distance of 423 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Louisville?

  • Can I find deals for flights from Missouri to Louisville that include hotel bookings?

    Yes. In addition to deals on Missouri to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Louisville.

  • Can I find deals for business class flights from Missouri to Louisville?

    Yes. Cheapflights offers flight deals from Missouri to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Louisville?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Louisville (average of $146). Flying from Missouri to Louisville in January is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Louisville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Missouri to Louisville

Discover the top 3 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$118Average$361FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$312FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$482FlexibilityNo cancel feeOn-time63%

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