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$122+ Cheap flights from Missouri to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
nov. 13 — nov. 201
jue. 11/13
jue. 11/20
1 adult, Economy
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Find flight deals from Missouri to Louisville

Cheapest flights from Missouri to Louisville
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/1311:12 amMCI - SDF
2 stops20h 52mMultiple Airlines
dom. 11/167:11 pmSDF - MCI
1 stop24h 17mMultiple Airlines
Deal found 10/12$235
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/286:00 amSGF - SDF
1 stop4h 49mDelta
sáb. 11/15:58 pmSDF - SGF
1 stop5h 11mDelta
Deal found 10/13$239
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/112:31 pmSTL - SDF
1 stop3h 45mUnited Airlines
mié. 11/511:00 amSDF - STL
1 stop5h 49mUnited Airlines
Deal found 10/11$257
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/88:00 amMCI - SDF
1 stop5h 07mDelta
mar. 11/116:00 amSDF - MCI
1 stop4h 18mDelta
Deal found 10/13$257
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/110:25 amSTL - SDF
2 stops8h 05mSouthwest
mié. 11/56:45 amSDF - STL
1 stop4h 55mSouthwest
Deal found 10/11$262
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/276:00 amSTL - SDF
1 stop4h 57mDelta
jue. 12/46:00 amSDF - STL
1 stop5h 45mDelta
Deal found 10/13$273
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/1410:22 amMCI - SDF
1 stop22h 32mMultiple Airlines
lun. 11/177:46 pmSDF - MCI
2 stops17h 42mMultiple Airlines
Deal found 10/13$277
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:29 amMCI - SDF
1 stop6h 20mDelta
sáb. 12/137:26 pmSDF - MCI
1 stop4h 44mDelta
Deal found 10/13$280
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/84:20 pmMCI - SDF
1 stop5h 05mSouthwest
mar. 11/1111:45 amSDF - MCI
2 stops5h 45mSouthwest
Deal found 10/13$285
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2710:53 amSTL - SDF
1 stop23h 10mMultiple Airlines
jue. 12/43:55 pmSDF - STL
2 stops26h 36mMultiple Airlines
Deal found 10/13$300
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/45:50 amMCI - SDF
1 stop7h 22mDelta
lun. 12/87:59 pmSDF - MCI
1 stop4h 56mDelta
Deal found 10/13$303
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:05 amSTL - SDF
1 stop6h 07mDelta
sáb. 12/137:05 amSDF - STL
1 stop6h 35mDelta
Deal found 10/12$307

Cheap flight deals from Missouri to Louisville

Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated octubre 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$229
(American Airlines)

One-way from

$122
(Delta)

Popular in

November

Cheapest in

April

Average price

$527
Provider with most accurate pricing for Lambert-St Louis-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Louisville Intl flights.
Search Deals
From Missouri to Louisville Intl
Search Deals
One-way flight from Missouri to Louisville Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.

Fly from

Missouri

Fly to

Louisville

Route

Depart

Return

Price

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

sáb. 2/21

4:28 pm-12:39 am

1 stop7h 11m

Louisville Intl

mié. 2/25

5:59 am-9:34 am

1 stop4h 35m

$229

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

mar. 10/28

6:00 am-11:49 am

1 stop4h 49m

Louisville Intl

sáb. 11/1

5:58 pm-10:09 pm

1 stop5h 11m

$239

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

sáb. 11/1

12:31 pm-5:16 pm

1 stop3h 45m

Louisville Intl

mié. 11/5

11:00 am-3:49 pm

1 stop5h 49m

$257

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

sáb. 11/8

8:00 am-2:07 pm

1 stop5h 07m

Louisville Intl

mar. 11/11

6:00 am-9:18 am

1 stop4h 18m

$257

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

mar. 11/11

12:18 pm-7:12 pm

1 stop5h 54m

Louisville Intl

mar. 11/18

7:26 pm-11:06 pm

1 stop4h 40m

$257

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

mar. 3/3

6:00 am-1:50 pm

1 stop6h 50m

Louisville Intl

mié. 3/4

6:36 am-10:32 am

1 stop4h 56m

$257

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

sáb. 11/1

10:25 am-7:30 pm

2 stops8h 05m

Louisville Intl

mié. 11/5

6:45 am-10:40 am

1 stop4h 55m

$262

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

mié. 1/14

6:00 am-6:39 pm

1 stop11h 39m

Louisville Intl

vie. 1/16

1:15 pm-6:34 pm

1 stop6h 19m

$270

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

jue. 11/27

6:00 am-11:57 am

1 stop4h 57m

Louisville Intl

jue. 12/4

6:00 am-10:45 am

1 stop5h 45m

$273

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

lun. 12/8

6:44 am-3:32 pm

1 stop7h 48m

Louisville Intl

sáb. 12/13

5:58 pm-12:03 am

1 stop7h 05m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Showing 1-10 of 48 results
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Best time to book a flight from Missouri to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Louisville

What is the cheapest month to book a flight from Missouri to Louisville?

Currently, December is the cheapest month in which you can book a flight from Missouri to Louisville (average of $114). Flying from Missouri to Louisville in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SDF?

Find hourly flight availability from Missouri to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 14, 2025.

It’s optimal to fly from Missouri to Louisville in the evening. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Missouri?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from Missouri to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How long is the flight from Missouri to Louisville?

    For as low as $257, American Airlines can have you in Louisville from Missouri in 3h 45m. Missouri and Louisville are separated by a distance of 254 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Louisville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $122. Allegiant Air flights start at $123 while deals on Southwest start at $134 one-way.

  • What are the most popular routes from Missouri to Louisville?

    When deciding which route to take from Missouri to Louisville consider Kansas City - Louisville Intl, Lambert-St Louis - Louisville Intl or Springfield-Branson - Louisville Intl as they are the most popular.

  • Can I find deals for flights from Missouri to Louisville that include hotel bookings?

    Yes. In addition to deals on Missouri to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Louisville.

  • Can I find deals for business class flights from Missouri to Louisville?

    Yes. Cheapflights offers flight deals from Missouri to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Louisville?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Louisville (average of $114). Flying from Missouri to Louisville in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Missouri to Louisville

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Top 4 airlines flying from Missouri to Louisville

Discover the top 4 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$336FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$498FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$228Average$336FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$462FlexibilityNo cancel feeOn-time69%

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