HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisville

$127+ Cheap flights from Missouri to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Louisville

Cheapest flights from Missouri to Louisville
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:24 pm
MCI
-
SDF
1 stop18h 57m
Spirit Airlines
Mon 2/231:19 pm
SDF
-
MCI
1 stop27h 10m
Spirit Airlines
Deal found 1/19$251
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:15 am
MCI
-
SDF
1 stop8h 36m
United Airlines
Tue 3/35:54 pm
SDF
-
MCI
1 stop5h 05m
United Airlines
Deal found 1/19$255
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:28 pm
MCI
-
SDF
2 stops14h 53m
Multiple Airlines
Mon 2/231:19 pm
SDF
-
MCI
1 stop27h 10m
Multiple Airlines
Deal found 1/19$280
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/181:30 pm
MCI
-
SDF
2 stops8h 15m
Southwest
Tue 3/35:35 am
SDF
-
MCI
1 stop6h 00m
Southwest
Deal found 1/19$290
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:24 am
MCI
-
SDF
1 stop5h 55m
United Airlines
Mon 3/25:54 pm
SDF
-
MCI
1 stop5h 05m
United Airlines
Deal found 1/19$293
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/181:30 pm
MCI
-
SDF
2 stops8h 15m
Southwest
Mon 3/24:15 pm
SDF
-
MCI
1 stop6h 20m
Southwest
Deal found 1/19$298
This United Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/213:22 pm
MCI
-
SDF
1 stop3h 47m
United Airlines
Sun 2/226:00 am
SDF
-
MCI
1 stop6h 56m
United Airlines
Deal found 1/18$301
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:06 pm
MCI
-
SDF
1 stop4h 41m
Delta
Wed 3/45:33 am
SDF
-
MCI
1 stop5h 00m
Delta
Deal found 1/18$305
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1611:26 am
MCI
-
SDF
1 stop26h 12m
Spirit Airlines
Mon 2/231:19 pm
SDF
-
MCI
1 stop27h 10m
Spirit Airlines
Deal found 1/19$311
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:39 am
STL
-
SDF
1 stop7h 17m
United Airlines
Wed 2/259:00 am
SDF
-
STL
1 stop4h 21m
United Airlines
Deal found 1/19$315
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1810:15 am
MCI
-
SDF
1 stop8h 36m
United Airlines
Sat 2/219:00 am
SDF
-
MCI
1 stop6h 24m
United Airlines
Deal found 1/19$315
This Delta deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:45 am
STL
-
SDF
1 stop5h 53m
Delta
Sun 7/197:30 pm
SDF
-
STL
1 stop5h 07m
Delta
Deal found 1/17$335

Find flight deals from Missouri to Louisville

Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated January 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$251
(Kiwi.com)

One-way from

$127
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$449
Provider with most accurate pricing for Lambert-St Louis-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Louisville Intl flights.
Search Deals
From Missouri to Louisville Intl
Search Deals
One-way flight from Missouri to Louisville Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.

Fly from

Missouri

Fly to

Louisville

Route

Depart

Return

Price

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Thu 2/19

4:24 pm-12:21 pm

1 stop18h 57m

Louisville Intl

Mon 2/23

1:19 pm-3:29 pm

1 stop27h 10m

$251

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 2/18

10:15 am-7:51 pm

1 stop8h 36m

Louisville Intl

Tue 3/3

5:54 pm-9:59 pm

1 stop5h 05m

$255

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 2/18

1:30 pm-10:45 pm

2 stops8h 15m

Louisville Intl

Tue 3/3

5:35 am-10:35 am

1 stop6h 00m

$290

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 2/18

10:24 am-5:19 pm

1 stop5h 55m

Louisville Intl

Mon 3/2

5:54 pm-9:59 pm

1 stop5h 05m

$293

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sat 2/21

3:22 pm-8:09 pm

1 stop3h 47m

Louisville Intl

Sun 2/22

6:00 am-11:56 am

1 stop6h 56m

$301

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sun 3/1

5:06 pm-10:47 pm

1 stop4h 41m

Louisville Intl

Wed 3/4

5:33 am-9:33 am

1 stop5h 00m

$305

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Tue 2/24

11:39 am-7:56 pm

1 stop7h 17m

Louisville Intl

Wed 2/25

9:00 am-12:21 pm

1 stop4h 21m

$315

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 2/18

11:32 am-5:19 pm

1 stop4h 47m

Louisville Intl

Sat 2/21

9:15 am-2:02 pm

1 stop5h 47m

$315

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sat 2/28

5:20 am-4:15 pm

2 stops9h 55m

Louisville Intl

Mon 3/2

6:25 am-2:10 pm

2 stops8h 45m

$316

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 2/18

12:55 pm-10:10 pm

2 stops8h 15m

Louisville Intl

Mon 3/2

6:25 am-2:10 pm

2 stops8h 45m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/18

Showing 1-10 of 42 results
1
2
3
...
5

Best time to book a flight from Missouri to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Louisville

What is the cheapest month to book a flight from Missouri to Louisville?

Currently, November is the cheapest month in which you can book a flight from Missouri to Louisville (average of $146). Flying from Missouri to Louisville in January is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Missouri?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from Missouri to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How long is the flight from Missouri to Louisville?

    For as low as $290, Spirit Airlines can have you in Louisville from Missouri in 8h 15m. Missouri and Louisville are separated by a distance of 490 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Louisville one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $108. Delta flights start at $118 while deals on United Airlines start at $128 one-way.

  • What are the most popular routes from Missouri to Louisville?

    When deciding which route to take from Missouri to Louisville consider Kansas City - Louisville Intl, Lambert-St Louis - Louisville Intl or Springfield-Branson - Louisville Intl as they are the most popular.

  • Can I find deals for flights from Missouri to Louisville that include hotel bookings?

    Yes. In addition to deals on Missouri to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Louisville.

  • Can I find deals for business class flights from Missouri to Louisville?

    Yes. Cheapflights offers flight deals from Missouri to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Louisville?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Louisville (average of $146). Flying from Missouri to Louisville in January is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
John F Kennedy Intl to Nashville flights
Boston to Nashville flights
Philadelphia to Nashville flights
LaGuardia to Nashville flights
Los Angeles to Nashville flights
Reagan-National to Nashville flights
O'Hare Intl to Nashville flights
Seattle to Nashville flights
Baltimore to Nashville flights
Dallas/Fort Worth to Nashville flights
Denver to Nashville flights
Dulles Intl to Nashville flights
Minneapolis to Nashville flights
Hobby to Nashville flights
San Francisco to Nashville flights
Detroit to Nashville flights
Newark to Cincinnati flights
George Bush Intcntl to Nashville flights
Orlando to Nashville flights
LaGuardia to Cincinnati flights
Sky Harbor Intl to Nashville flights
LaGuardia to Knoxville flights
Hartford to Nashville flights
Ontario to Nashville flights
Raleigh to Nashville flights
Fort Lauderdale to Nashville flights
Austin to Nashville flights
Cleveland to Nashville flights
Pittsburgh to Nashville flights
LaGuardia to Louisville flights
Denver to Cincinnati flights
Tampa to Nashville flights
Miami to Nashville flights
Richmond to Nashville flights
John F Kennedy Intl to Cincinnati flights
Newark to Louisville flights
Sacramento to Nashville flights
San Diego to Nashville flights
Salt Lake City to Nashville flights
Charlotte to Nashville flights
John F Kennedy Intl to Knoxville flights
Providence to Nashville flights
Portland to Nashville flights
Midway to Nashville flights
Boston to Cincinnati flights
Denver to Knoxville flights
O'Hare Intl to Knoxville flights
John F Kennedy Intl to Louisville flights
Milwaukee to Nashville flights

Top 3 airlines flying from Missouri to Louisville

Discover the top 3 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$322FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$310FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$489FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.