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$129+ Cheap flights from Missouri to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Dec 31 — Jan 71
Wed 12/31
Wed 1/7
1 adult, Economy
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Find flight deals from Missouri to Louisville

Cheapest flights from Missouri to Louisville
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 1, 2025.

This United Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:31 amSGF - SDF
1 stop4h 45mUnited Airlines
Sun 12/149:31 amSDF - SGF
1 stop5h 33mUnited Airlines
Deal found 11/28$259
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:00 amSGF - SDF
2 stops7h 35mAmerican Airlines
Sat 12/206:27 amSDF - SGF
1 stop4h 30mAmerican Airlines
Deal found 12/1$264
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:18 amSTL - SDF
1 stop7h 01mAmerican Airlines
Sat 1/35:00 amSDF - STL
1 stop4h 35mAmerican Airlines
Deal found 12/1$270
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:37 pmSTL - SDF
2 stops26h 22mMultiple Airlines
Mon 1/58:53 pmSDF - STL
1 stop15h 03mMultiple Airlines
Deal found 11/29$291
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 pmMCI - SDF
1 stop27h 34mMultiple Airlines
Tue 12/302:55 pmSDF - MCI
2 stops27h 15mMultiple Airlines
Deal found 11/30$291
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 pmMCI - SDF
1 stop27h 34mSpirit Airlines
Tue 12/305:05 amSDF - MCI
1 stop13h 05mSpirit Airlines
Deal found 11/30$301
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:53 pmSGF - SDF
1 stop4h 06mDelta
Sun 12/77:15 amSDF - SGF
1 stop4h 35mDelta
Deal found 12/1$319
This American Airlines deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 amMCI - SDF
1 stop7h 18mAmerican Airlines
Sat 1/37:53 amSDF - MCI
1 stop7h 59mAmerican Airlines
Deal found 11/29$330
This American Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:35 amMCI - SDF
2 stops10h 44mAmerican Airlines
Sun 12/288:00 amSDF - MCI
1 stop7h 52mAmerican Airlines
Deal found 11/28$335
This United Airlines deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:02 pmSTL - SDF
1 stop4h 28mUnited Airlines
Fri 1/29:05 amSDF - STL
1 stop6h 21mUnited Airlines
Deal found 11/29$337
This Delta deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/134:08 pmSGF - SDF
1 stop6h 51mDelta
Sun 12/147:15 amSDF - SGF
1 stop4h 35mDelta
Deal found 12/1$339
This American Airlines deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:41 amSTL - SDF
1 stop5h 49mAmerican Airlines
Fri 1/28:00 amSDF - STL
2 stops9h 23mAmerican Airlines
Deal found 11/29$342

Cheap flight deals from Missouri to Louisville

Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated December 1, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$189
(Southwest)

One-way from

$129
(Delta)

Popular in

July

Cheapest in

April

Average price

$435
Provider with most accurate pricing for Lambert-St Louis-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Louisville Intl flights.
Search Deals
From Missouri to Louisville Intl
Search Deals
One-way flight from Missouri to Louisville Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.

Fly from

Missouri

Fly to

Louisville

Route

Depart

Return

Price

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

Tue 2/17

5:11 pm-11:58 pm

1 stop5h 47m

Louisville Intl

Sat 2/21

8:55 am-12:09 pm

1 stop4h 14m

$244

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Tue 1/20

1:00 pm-7:39 pm

1 stop5h 39m

Louisville Intl

Sat 1/24

5:35 am-8:53 am

1 stop4h 18m

$257

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Wed 2/18

8:05 am-2:34 pm

1 stop5h 29m

Louisville Intl

Sat 2/21

5:00 pm-9:07 pm

1 stop5h 07m

$257

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

Sat 12/13

11:31 am-5:16 pm

1 stop4h 45m

Louisville Intl

Sun 12/14

9:31 am-2:04 pm

1 stop5h 33m

$259

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

Tue 12/16

8:00 am-3:32 pm

1 stop6h 32m

Louisville Intl

Sat 12/20

6:27 am-9:57 am

1 stop4h 30m

$259

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Thu 1/15

1:05 pm-11:00 pm

2 stops8h 55m

Louisville Intl

Mon 1/19

7:25 pm-10:10 pm

1 stop3h 45m

$270

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Wed 12/31

9:18 am-5:19 pm

1 stop7h 01m

Louisville Intl

Sat 1/3

5:00 am-8:35 am

1 stop4h 35m

$270

St. LouisLouisville

STL - SDF

STLSDF

Lambert-St Louis

Fri 12/19

8:37 pm-11:59 pm

2 stops26h 22m

Louisville Intl

Mon 1/5

8:53 pm-10:56 am

1 stop15h 03m

$291

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Mon 12/22

6:15 pm-10:49 pm

1 stop27h 34m

Louisville Intl

Tue 12/30

2:55 pm-5:10 pm

2 stops27h 15m

$291

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Fri 1/16

3:35 pm-9:25 pm

1 stop4h 50m

Louisville Intl

Mon 1/19

5:25 am-10:40 am

1 stop6h 15m

$296

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/29

Showing 1-10 of 37 results
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Best time to book a flight from Missouri to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Louisville

What is the cheapest month to book a flight from Missouri to Louisville?

Currently, December is the cheapest month in which you can book a flight from Missouri to Louisville (average of $110). Flying from Missouri to Louisville in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SDF?

Find hourly flight availability from Missouri to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 1, 2025.

It’s optimal to fly from Missouri to Louisville in the evening. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Missouri to Louisville?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Missouri?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from Missouri to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How long is the flight from Missouri to Louisville?

    For as low as $259, Delta can have you in Louisville from Missouri in 4h 45m. Missouri and Louisville are separated by a distance of 423 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Louisville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $129. American Airlines flights start at $152 while deals on United Airlines start at $250 one-way.

  • What are the most popular routes from Missouri to Louisville?

    When deciding which route to take from Missouri to Louisville consider Kansas City - Louisville Intl, Lambert-St Louis - Louisville Intl or Springfield-Branson - Louisville Intl as they are the most popular.

  • Can I find deals for flights from Missouri to Louisville that include hotel bookings?

    Yes. In addition to deals on Missouri to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Louisville.

  • Can I find deals for business class flights from Missouri to Louisville?

    Yes. Cheapflights offers flight deals from Missouri to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Louisville?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Louisville (average of $110). Flying from Missouri to Louisville in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from Missouri to Louisville

Discover the top 3 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$310FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$494FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$241Average$324FlexibilityNo cancel feeOn-time71%

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