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$99+ Cheap flights from Missouri to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDF
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Missouri to Louisville

Keep the following information in mind while searching for Missouri to Louisville flight deals. Data was last updated August 18, 2025.

Round-trip from

$199
(FlightHub)

One-way from

$99
(FlightHub)

Popular in

May

Cheapest in

January

Average price

$384
From Missouri to Louisville Intl
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One-way flight from Missouri to Louisville Intl
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Highest demand for flights based on searches. 11% potential increase in price ($48 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Missouri to Louisville

Cheapest flights from Missouri to Louisville
Explore the most affordable flight options available from Missouri to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:44 pmMCI - SDF
1 stop9h 01mSpirit Airlines
Sun 12/146:00 amSDF - MCI
1 stop7h 39mSpirit Airlines
Deal found 8/17$199
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:44 pmMCI - SDF
1 stop9h 01mSpirit Airlines
Tue 11/186:00 amSDF - MCI
1 stop28h 04mSpirit Airlines
Deal found 8/17$215
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2611:13 amMCI - SDF
1 stop9h 51mSpirit Airlines
Mon 9/2910:14 amSDF - MCI
1 stop13h 53mSpirit Airlines
Deal found 8/18$222
This FlightHub deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1911:13 amMCI - SDF
1 stop9h 51mSpirit Airlines
Sun 9/218:23 amSDF - MCI
1 stop26h 55mSpirit Airlines
Deal found 8/15$229
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/75:15 amMCI - SDF
1 stop27h 04mSpirit Airlines
Wed 9/1010:14 amSDF - MCI
1 stop13h 53mSpirit Airlines
Deal found 8/16$231
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:15 amMCI - SDF
1 stop27h 04mSpirit Airlines
Sun 9/218:23 amSDF - MCI
1 stop26h 55mSpirit Airlines
Deal found 8/15$235
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:25 pmSTL - SDF
1 stop4h 17mDelta
Sun 8/318:10 amSDF - STL
1 stop5h 21mDelta
Deal found 8/15$237
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:15 amMCI - SDF
1 stop16h 32mSpirit Airlines
Sun 10/266:58 pmSDF - MCI
1 stop22h 18mSpirit Airlines
Deal found 8/16$238
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:15 amMCI - SDF
1 stop6h 38mDelta
Thu 10/168:15 pmSDF - MCI
1 stop4h 37mDelta
Deal found 8/17$244
This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1211:13 amMCI - SDF
1 stop9h 51mSpirit Airlines
Mon 9/1510:14 amSDF - MCI
1 stop13h 53mSpirit Airlines
Deal found 8/16$245
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:45 amMCI - SDF
1 stop5h 20mSouthwest
Tue 11/186:45 amSDF - MCI
2 stops5h 45mSouthwest
Deal found 8/17$249
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:15 amMCI - SDF
1 stop27h 04mSpirit Airlines
Sat 9/2010:14 amSDF - MCI
1 stop13h 53mSpirit Airlines
Deal found 8/16$251

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Missouri to Louisville that are best for you.

Fly from

Missouri

Fly to

Louisville

Route

Depart

Return

Price

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Thu 12/11

1:44 pm-11:45 pm

1 stop9h 01m

Louisville Intl

Sun 12/14

6:00 am-12:39 pm

1 stop7h 39m

$199

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sat 11/15

1:44 pm-11:45 pm

1 stop9h 01m

Louisville Intl

Tue 11/18

6:00 am-9:04 am

1 stop28h 04m

$215

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sat 11/15

1:44 pm-11:45 pm

1 stop9h 01m

Louisville Intl

Sun 11/16

6:00 am-9:04 am

1 stop28h 04m

$215

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sat 11/15

1:44 pm-11:45 pm

1 stop9h 01m

Louisville Intl

Mon 11/17

6:00 am-9:04 am

1 stop28h 04m

$215

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Fri 9/26

11:13 am-10:04 pm

1 stop9h 51m

Louisville Intl

Mon 9/29

10:14 am-11:07 pm

1 stop13h 53m

$222

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

Wed 1/28

3:03 pm-10:09 pm

1 stop6h 06m

Louisville Intl

Sat 1/31

3:50 pm-9:28 pm

1 stop6h 38m

$229

SpringfieldLouisville

SGF - SDF

SGFSDF

Springfield-Branson

Sat 11/22

6:34 pm-12:22 am

1 stop4h 48m

Louisville Intl

Sat 12/6

6:51 am-11:24 am

1 stop5h 33m

$229

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Fri 9/19

11:13 am-10:04 pm

1 stop9h 51m

Louisville Intl

Sun 9/21

8:23 am-10:18 am

1 stop26h 55m

$229

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Sun 9/7

5:15 am-9:19 am

1 stop27h 04m

Louisville Intl

Wed 9/10

10:14 am-11:07 pm

1 stop13h 53m

$231

Kansas CityLouisville

MCI - SDF

MCISDF

Kansas City

Thu 9/18

5:15 am-9:19 am

1 stop27h 04m

Louisville Intl

Sun 9/21

8:23 am-10:18 am

1 stop26h 55m

$235

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 42 results
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Best time to book a flight from Missouri to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Louisville

What is the cheapest month to book a flight from Missouri to Louisville?

Currently, January is the cheapest month in which you can book a flight from Missouri to Louisville (average of $299). Flying from Missouri to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SDF?

Find hourly flight availability from Missouri to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Louisville as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Missouri?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from Missouri to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How long is the flight from Missouri to Louisville?

    For as low as $229, Spirit Airlines can have you in Louisville from Missouri in 4h 48m. Missouri and Louisville are separated by a distance of 423 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Louisville one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $99. United Airlines flights start at $119 while deals on Delta start at $119 one-way.

  • What are the most popular routes from Missouri to Louisville?

    When deciding which route to take from Missouri to Louisville consider Kansas City - Louisville Intl, Lambert-St Louis - Louisville Intl or Joplin - Louisville Intl as they are the most popular.

  • Can I find deals for flights from Missouri to Louisville that include hotel bookings?

    Yes. In addition to deals on Missouri to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Louisville.

  • Can I find deals for business class flights from Missouri to Louisville?

    Yes. Cheapflights offers flight deals from Missouri to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Louisville (average of $299). Flying from Missouri to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Missouri to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Louisville

Discover the top 4 airlines that operate flights from Missouri to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$226Average$494FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$228Average$332FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$462FlexibilityNo cancel feeOn-time69%
DeltaCheapest$281Average$354FlexibilityNo cancel feeOn-timeN/A

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