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$126+ Cheap flights from Biloxi, MS to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SDF
Mar 9 — Mar 161
Mon 3/9
Mon 3/16
1 adult, Economy
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Cheap flight deals from Biloxi to Louisville

Cheapest flights from Biloxi to Louisville
Explore the most affordable flight options available from Biloxi to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.

This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:57 pm
GPT
-
SDF
1 stop3h 46m
Delta
Tue 4/76:00 am
SDF
-
GPT
1 stop3h 50m
Delta
Deal found 2/3$325
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/132:00 pm
GPT
-
SDF
2 stops8h 59m
United Airlines
Tue 6/163:30 pm
SDF
-
GPT
1 stop6h 57m
United Airlines
Deal found 2/7$355
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/54:29 pm
GPT
-
SDF
1 stop6h 58m
American Airlines
Tue 4/77:31 am
SDF
-
GPT
2 stops10h 48m
American Airlines
Deal found 2/3$367
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:00 pm
GPT
-
SDF
1 stop6h 30m
United Airlines
Wed 11/49:32 am
SDF
-
GPT
1 stop4h 54m
United Airlines
Deal found 2/6$374
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:29 pm
GPT
-
SDF
1 stop6h 58m
American Airlines
Sun 3/297:57 pm
SDF
-
GPT
1 stop5h 00m
American Airlines
Deal found 2/4$386
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:03 pm
GPT
-
SDF
1 stop5h 08m
American Airlines
Fri 5/157:52 pm
SDF
-
GPT
1 stop5h 06m
American Airlines
Deal found 2/5$389
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:18 am
GPT
-
SDF
1 stop6h 12m
American Airlines
Sun 9/207:58 am
SDF
-
GPT
1 stop4h 39m
American Airlines
Deal found 2/5$454
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/77:00 am
GPT
-
SDF
2 stops11h 31m
United Airlines
Tue 2/103:30 pm
SDF
-
GPT
1 stop5h 18m
United Airlines
Deal found 2/4$475

Find flight deals from Biloxi to Louisville

Keep the following information in mind while searching for Biloxi to Louisville flight deals. Data was last updated February 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$325
(Delta)

One-way from

$126
(Kiwi.com)

Popular in

October

Cheapest in

August

Average price

$492
Provider with most accurate pricing for Gulfport Biloxi Regional-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Louisville Intl flights.
Search Deals
From Biloxi to Louisville Intl
Search Deals
One-way flight from Biloxi to Louisville Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Biloxi to Louisville that are best for you.

Fly from

Biloxi

Fly to

Louisville

Route

Depart

Return

Price

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sun 4/5

5:57 pm-10:43 pm

1 stop3h 46m

Louisville Intl

Tue 4/7

6:00 am-8:50 am

1 stop3h 50m

$325

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 6/13

2:00 pm-11:59 pm

2 stops8h 59m

Louisville Intl

Tue 6/16

3:30 pm-9:27 pm

1 stop6h 57m

$355

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sun 4/5

4:29 pm-12:27 am

1 stop6h 58m

Louisville Intl

Tue 4/7

7:31 am-5:19 pm

2 stops10h 48m

$367

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Fri 3/27

4:29 pm-12:27 am

1 stop6h 58m

Louisville Intl

Sun 3/29

7:57 pm-11:57 pm

1 stop5h 00m

$386

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 6/13

12:38 pm-7:30 pm

1 stop5h 52m

Louisville Intl

Tue 6/16

8:15 pm-11:57 pm

1 stop4h 42m

$389

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Mon 5/11

5:03 pm-11:11 pm

1 stop5h 08m

Louisville Intl

Fri 5/15

7:52 pm-11:58 pm

1 stop5h 06m

$389

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Thu 5/21

11:25 am-6:58 pm

1 stop6h 33m

Louisville Intl

Thu 5/21

8:15 pm-11:57 pm

1 stop4h 42m

$589

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sun 2/22

7:20 pm-12:21 pm

1 stop16h 01m

Louisville Intl

Thu 2/26

2:26 pm-9:00 am

2 stops19h 34m

$608

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sun 5/17

7:50 pm-11:38 am

1 stop14h 48m

$126

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 3/7

3:00 pm-8:28 pm

1 stop4h 28m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

Showing 1-10 of 14 results
1
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Best time to book a flight from Biloxi to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Louisville

What is the cheapest month to book a flight from Biloxi to Louisville?

Currently, February is the cheapest month in which you can book a flight from Biloxi to Louisville (average of $56). Flying from Biloxi to Louisville in March is currently the most expensive (average of $181). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated February 7, 2026.
Get a feel of what it's like to fly with Delta from Biloxi to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,169 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,169 reviews
Delta
7.9
Good
8,169 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Biloxi?

    Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Biloxi to Louisville. 5 airlines have flights to Louisville Intl from Biloxi on a regular basis. Booking flights from Biloxi to Louisville Intl should not be difficult; the airport handles an average of 0 inbound flights from Biloxi per day.

  • How long is the flight from Biloxi to Louisville?

    Departing from Biloxi to Louisville will take you 3h 46m. Airlines will cover a distance of 569 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Biloxi to Louisville that include hotel bookings?

    Yes. In addition to deals on Biloxi to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Louisville.

  • Can I find deals for business class flights from Biloxi to Louisville?

    Yes. Cheapflights offers flight deals from Biloxi to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Louisville?

    Currently, February is the cheapest month in which you can book a flight from Biloxi to Louisville (average of $56). Flying from Biloxi to Louisville in March is currently the most expensive (average of $181). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 5 airlines flying from Biloxi to Louisville

Discover the top 5 airlines that operate flights from Biloxi to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$122Average$271FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$186Average$230FlexibilityNo cancel feeOn-time65%
DeltaCheapest$226Average$336FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$272Average$412FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$287Average$386FlexibilityNo cancel feeOn-time71%

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