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$125+ Cheap flights from Biloxi, MS to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SDF
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Biloxi to Louisville

Cheapest flights from Biloxi to Louisville
Explore the most affordable flight options available from Biloxi to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:38 pmGPT - SDF
1 stop4h 36mAmerican Airlines
Mon 12/297:24 pmSDF - GPT
1 stop5h 48mAmerican Airlines
Deal found 12/17$354
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:41 pmGPT - SDF
1 stop4h 51mAmerican Airlines
Tue 12/307:24 pmSDF - GPT
1 stop5h 48mAmerican Airlines
Deal found 12/16$359
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:38 pmGPT - SDF
1 stop6h 38mAmerican Airlines
Mon 12/297:24 pmSDF - GPT
1 stop5h 48mAmerican Airlines
Deal found 12/17$384
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:57 pmGPT - SDF
1 stop6h 57mUnited Airlines
Tue 12/3010:50 amSDF - GPT
2 stops11h 47mUnited Airlines
Deal found 12/16$446

Find flight deals from Biloxi to Louisville

Keep the following information in mind while searching for Biloxi to Louisville flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$443
(United Airlines)

One-way from

$125
(American Airlines)

Popular in

October

Cheapest in

August

Average price

$522
Provider with most accurate pricing for Gulfport Biloxi Regional-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Louisville Intl flights.
Search Deals
From Biloxi to Louisville Intl
Search Deals
One-way flight from Biloxi to Louisville Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($47 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Biloxi to Louisville that are best for you.

Fly from

Biloxi

Fly to

Louisville

Route

Depart

Return

Price

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 1/31

7:00 am-8:28 pm

2 stops12h 28m

Louisville Intl

Wed 2/4

9:00 am-7:48 pm

2 stops11h 48m

$443

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 1/17

6:32 am-12:25 pm

1 stop4h 53m

$125

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Fri 1/16

6:32 am-12:25 pm

1 stop4h 53m

$234

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 1/17

7:00 am-7:31 pm

2 stops11h 31m

$239

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Fri 1/16

6:54 pm-7:37 pm

3 stops47h 43m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Best time to book a flight from Biloxi to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Louisville

What is the cheapest month to book a flight from Biloxi to Louisville?

Currently, January is the cheapest month in which you can book a flight from Biloxi to Louisville (average of $64). Flying from Biloxi to Louisville in August is currently the most expensive (average of $223). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to SDF?

Find hourly flight availability from Biloxi to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Biloxi to Louisville in the afternoon. By choosing this option you can save up to 26% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with Delta from Biloxi to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Biloxi?

    Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Biloxi to Louisville. 5 airlines have flights to Louisville Intl from Biloxi on a regular basis. Booking flights from Biloxi to Louisville Intl should not be difficult; the airport handles an average of 0 inbound flights from Biloxi per day.

  • How long is the flight from Biloxi to Louisville?

    Departing from Biloxi to Louisville will take you 12h 28m. Airlines will cover a distance of 569 mi.

  • Can I find deals for flights from Biloxi to Louisville that include hotel bookings?

    Yes. In addition to deals on Biloxi to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Louisville.

  • Can I find deals for business class flights from Biloxi to Louisville?

    Yes. Cheapflights offers flight deals from Biloxi to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Biloxi to Louisville (average of $64). Flying from Biloxi to Louisville in August is currently the most expensive (average of $223). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 5 airlines flying from Biloxi to Louisville

Discover the top 5 airlines that operate flights from Biloxi to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$122Average$260FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$186Average$230FlexibilityNo cancel feeOn-time65%
DeltaCheapest$198Average$363FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$244Average$353FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$272Average$422FlexibilityNo cancel feeOn-time63%

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