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$261+ Cheap flights from Biloxi, MS to Louisville (SDF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SDF
Jul 29 — Aug 51
Wed 7/29
Wed 8/5
1 adult, Economy
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Cheap flight deals from Biloxi to Louisville

Cheapest flights from Biloxi to Louisville
Explore the most affordable flight options available from Biloxi to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.

This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:50 pm
GPT
-
SDF
1 stop6h 41m
American Airlines
Tue 8/117:12 pm
SDF
-
GPT
1 stop4h 18m
American Airlines
Deal found 6/25$261
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:35 pm
GPT
-
SDF
1 stop4h 59m
American Airlines
Sun 8/28:19 pm
SDF
-
GPT
1 stop4h 37m
American Airlines
Deal found 6/27$311
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:57 pm
GPT
-
SDF
1 stop5h 29m
Delta
Sun 8/21:02 pm
SDF
-
GPT
1 stop5h 10m
Delta
Deal found 6/27$341
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:35 pm
GPT
-
SDF
1 stop4h 59m
American Airlines
Wed 7/155:04 am
SDF
-
GPT
1 stop6h 07m
American Airlines
Deal found 6/26$347
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:27 am
GPT
-
SDF
1 stop6h 31m
American Airlines
Tue 7/145:04 am
SDF
-
GPT
1 stop6h 07m
American Airlines
Deal found 6/25$379
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:00 pm
GPT
-
SDF
1 stop4h 59m
United Airlines
Wed 8/263:35 pm
SDF
-
GPT
1 stop5h 03m
United Airlines
Deal found 6/28$380
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:54 pm
GPT
-
SDF
1 stop6h 36m
United Airlines
Tue 12/87:30 am
SDF
-
GPT
3 stops14h 57m
United Airlines
Deal found 6/24$390
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:06 am
GPT
-
SDF
1 stop6h 43m
Delta
Mon 7/136:00 am
SDF
-
GPT
1 stop4h 19m
Delta
Deal found 6/26$419

Find flight deals from Biloxi to Louisville

Keep the following information in mind while searching for Biloxi to Louisville flight deals. Data was last updated June 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$261
(American Airlines)

Popular in

May

Cheapest in

August

Average price

$378
Provider with most accurate pricing for Gulfport Biloxi Regional-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Louisville Intl flights.
Search Deals
From Biloxi to Louisville Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Biloxi to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 8/8

5:31 am-12:49 pm

1 stop6h 18m

Louisville Intl

Tue 8/11

7:12 pm-10:30 pm

1 stop4h 18m

$261

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Fri 7/31

5:57 pm-12:26 am

1 stop5h 29m

Louisville Intl

Sun 8/2

1:02 pm-5:12 pm

1 stop5h 10m

$341

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 7/11

6:35 pm-12:34 am

1 stop4h 59m

Louisville Intl

Wed 7/15

5:04 am-10:11 am

1 stop6h 07m

$347
Quickest round-trip

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 8/22

2:00 pm-7:59 pm

1 stop4h 59m

Louisville Intl

Wed 8/26

3:35 pm-7:38 pm

1 stop5h 03m

$380

GulfportLouisville

GPT - SDF

GPTSDF

Gulfport Biloxi Regional

Sat 12/5

1:54 pm-7:35 pm

1 stop4h 41m

Louisville Intl

Tue 12/8

7:30 am-4:02 pm

2 stops9h 32m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Sorted by cheapest first

Best time to book a flight from Biloxi to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Louisville

What is the cheapest time of day to fly from B1L to SDF?

Find hourly flight availability from Biloxi to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 29, 2026.

When flying from Biloxi to Louisville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 29, 2026.
Get a feel of what it's like to fly with Delta from Biloxi to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,449 reviews

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,449 reviews
Delta
7.8
Good
8,449 reviews

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.8

Overall

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Biloxi?

    Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Biloxi to Louisville. 4 airlines have flights to Louisville Intl from Biloxi on a regular basis. Booking flights from Biloxi to Louisville Intl should not be difficult; the airport handles an average of 0 inbound flights from Biloxi per day.

  • How long is the flight from Biloxi to Louisville?

    Departing from Biloxi to Louisville will take you 4h 59m. Airlines will cover a distance of 569 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Biloxi to Louisville that include hotel bookings?

    Yes. In addition to deals on Biloxi to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Louisville.

  • Can I find deals for business class flights from Biloxi to Louisville?

    Yes. Cheapflights offers flight deals from Biloxi to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

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Top 4 airlines flying from Biloxi to Louisville

Discover the top 4 airlines that operate flights from Biloxi to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$133Average$271FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$226Average$375FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$386FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$304Average$412FlexibilityNo cancel feeOn-time63%

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