$220+ Cheap flights from Biloxi, MS to Louisville (SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SDF
Sep 25 — Oct 21
Round-trip
1 adult, Economy
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Find cheap flights from Biloxi to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Biloxi to Louisville
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Best
Last-minute
One-way
Cheapest flights from Biloxi to LouisvilleExplore the most affordable flight options available from Biloxi to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
Explore the most affordable flight options available from Biloxi to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 26, 2026.
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 pm -
1 stop5h 53m
Mon 12/284:38 pm -
1 stop6h 02m
Deal found 8/23![Delta logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:42 pm -
1 stop4h 40m
Sun 10/46:00 am -
1 stop5h 40m
Deal found 8/24![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:12 am -
1 stop5h 11m
Sat 8/297:12 pm -
1 stop4h 18m
Deal found 8/23![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:00 pm -
1 stop7h 15m
Sat 8/297:10 am -
2 stops10h 02m
Deal found 8/23![United Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 pm -
1 stop5h 34m
Fri 9/116:00 am -
1 stop4h 21m
Deal found 8/23![Delta logo]()
$527
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:00 am -
2 stops10h 40m
Mon 12/287:58 pm -
1 stop4h 59m
Deal found 8/23![American Airlines logo]()
$687
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:50 pm -
1 stop6h 41m
Tue 9/85:29 pm -
1 stop6h 47m
Deal found 8/21![American Airlines logo]()
$688
Best flights from Biloxi to LouisvilleDiscover carefully curated flight deals from Biloxi to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
Discover carefully curated flight deals from Biloxi to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 26, 2026.
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 pm -
1 stop5h 53m
Mon 12/284:38 pm -
1 stop6h 02m
Deal found 8/23![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/71:54 pm -
1 stop6h 36m
Mon 1/115:30 am -
3 stops15h 12m
Deal found 8/25![United Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:42 pm -
2 stops8h 13m
Sun 10/46:00 am -
1 stop5h 40m
Deal found 8/24![American Airlines logo]()
$598
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 pm -
1 stop5h 34m
Fri 9/116:00 am -
1 stop4h 21m
Deal found 8/23![Delta logo]()
$527
Last-minute flights from Biloxi to LouisvilleDiscover last-minute flight deals from Biloxi to Louisville. Data last updated August 26, 2026 and is based on user searches.
Discover last-minute flight deals from Biloxi to Louisville. Data last updated August 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:12 am -
1 stop5h 11m
Sat 8/297:12 pm -
1 stop4h 18m
Deal found 8/23![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:00 pm -
1 stop7h 15m
Sat 8/297:10 am -
2 stops10h 02m
Deal found 8/23![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:50 pm -
1 stop6h 41m
Tue 9/85:29 pm -
1 stop6h 47m
Deal found 8/21![American Airlines logo]()
$688
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 pm -
1 stop5h 34m
Fri 9/116:00 am -
1 stop4h 21m
Deal found 8/23![Delta logo]()
$527
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:45 pm -
1 stop4h 26m
Fri 9/117:30 am -
2 stops10h 42m
Deal found 8/23![American Airlines logo]()
$860
One-way flights from Biloxi to LouisvilleSearch for one-way flight options from Biloxi to Louisville. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
Search for one-way flight options from Biloxi to Louisville. Find affordable one-way fares based on user searches. Data last updated August 26, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:42 pm -
1 stop4h 26m
Deal found 8/23![American Airlines logo]()
$220
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:14 pm -
2 stops15h 20m
Deal found 8/23![United Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/74:59 pm -
1 stop28h 16m
Deal found 8/23![United Airlines logo]()
$608
Find flight deals from Biloxi to Louisville
Keep the following information in mind while searching for Biloxi to Louisville flight deals. Data was last updated August 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (American Airlines) |
One-way from | $220 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Biloxi to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
Use the filters below to find and compare flights from Biloxi to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Wed 12/23
5:30 pm-12:23 am
1 stop5h 53m
Louisville Intl
Mon 12/28
4:38 pm-9:40 pm
1 stop6h 02m
$341
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Thu 1/7
1:54 pm-9:30 pm
1 stop6h 36m
Louisville Intl
Mon 1/11
5:30 am-7:42 pm
3 stops15h 12m
$454
Quickest round-trip
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Mon 9/7
6:00 pm-12:34 am
1 stop5h 34m
Louisville Intl
Fri 9/11
6:00 am-9:21 am
1 stop4h 21m
$527
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Thu 10/1
1:42 pm-10:55 pm
2 stops8h 13m
Louisville Intl
Sun 10/4
6:00 am-10:40 am
1 stop5h 40m
$598
Cheapest one-way
Quickest one-way
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Thu 10/8
6:42 pm-12:08 am
1 stop4h 26m
$220
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Thu 10/8
5:14 pm-9:34 am
2 stops15h 20m
$438
GulfportLouisville
GPT Gulfport Biloxi Regional - SDF Louisville Intl
GPTSDF
Gulfport Biloxi Regional
Mon 9/7
4:59 pm-8:09 pm
2 stops26h 10m
$614
Sorted by cheapest first
Best time to book a flight from Biloxi to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Biloxi with our price prediction graph.
GPT-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Biloxi to Louisville
B1L-SDF
GPT-SDF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated August 26, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Biloxi to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Biloxi to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsCorydon
Shepherdsville
Elizabethtown
Jeffersonville
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Alternative routes for Biloxi to Louisville
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Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2026.
Biloxi and Louisville flights
Browse other Biloxi and Louisville flight options. Last updated on August 26, 2026.
Popular flight searches
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Biloxi to Louisville flights
Consider these flights traveling from Biloxi to Louisville.
Top 4 airlines flying from Biloxi to Louisville
Discover the top 4 airlines that operate flights from Biloxi to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$138 | Average$281 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$238 | Average$401 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$301 | Average$403 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$313 | Average$374 | FlexibilityNo cancel fee | On-time71% |