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Lisbon

$216+ Cheap flights from South Carolina to Lisbon (LIS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LIS
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Find flight deals from South Carolina to Lisbon

Cheapest flights from South Carolina to Lisbon
Explore the most affordable flight options available from South Carolina to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This United deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1710:00 amGSP - LIS
1 stop19h 15mMultiple Airlines
mié. 12/35:00 amLIS - GSP
2 stops23h 59mMultiple Airlines
Deal found 10/30$486
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/87:47 pmCHS - LIS
1 stop9h 28mUnited Airlines
mar. 12/2311:20 amLIS - CHS
2 stops36h 44mUnited Airlines
Deal found 10/29$486
This Air Canada deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/2410:00 amGSP - LIS
2 stops42h 20mAir Canada
mar. 12/911:20 amLIS - GSP
2 stops31h 57mAir Canada
Deal found 10/28$491
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/27:11 amSAV - LIS
2 stops21h 09mUnited Airlines
mié. 12/1011:00 amLIS - SAV
2 stops32h 27mUnited Airlines
Deal found 10/30$493
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/57:45 pmCHS - LIS
1 stop9h 30mUnited Airlines
vie. 12/511:20 amLIS - CHS
2 stops31h 35mUnited Airlines
Deal found 10/29$493
This Air Canada deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/259:10 amGSP - LIS
2 stops42h 45mAir Canada
mar. 12/911:20 amLIS - GSP
2 stops38h 29mAir Canada
Deal found 10/28$498
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/172:55 pmGSP - LIS
1 stop14h 20mUnited Airlines
mié. 12/311:55 amLIS - GSP
1 stop12h 15mUnited Airlines
Deal found 10/30$500
This Finnair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/53:46 pmCHS - LIS
1 stop12h 09mMultiple Airlines
vie. 12/511:05 amLIS - CHS
1 stop17h 13mMultiple Airlines
Deal found 10/29$502
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/23:20 pmSAV - LIS
1 stop11h 40mKLM
mié. 12/1010:00 amLIS - SAV
1 stop16h 35mKLM
Deal found 10/30$506
This United deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/2410:00 amGSP - LIS
1 stop19h 15mMultiple Airlines
lun. 12/82:10 pmLIS - GSP
2 stops38h 49mMultiple Airlines
Deal found 10/28$507
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/242:55 pmGSP - LIS
1 stop14h 20mUnited Airlines
mar. 12/911:55 amLIS - GSP
1 stop12h 15mUnited Airlines
Deal found 10/28$509
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/72:55 pmCHS - LIS
1 stop13h 00mDelta
mar. 12/2311:15 amLIS - CHS
1 stop30h 07mDelta
Deal found 10/29$514

Cheap flight deals from South Carolina to Lisbon

Keep the following information in mind while searching for South Carolina to Lisbon flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$486
(United)

One-way from

$216
(American Airlines)

Popular in

December

Cheapest in

February

Average price

$814
Provider with most accurate pricing for Myrtle Beach Intl-Lisbon Humberto Delgado flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Lisbon Humberto Delgado flights.
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From South Carolina to Lisbon Humberto Delgado
Search Deals
One-way flight from South Carolina to Lisbon Humberto Delgado
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from South Carolina to Lisbon that are best for you.

Fly from

South Carolina

Fly to

Lisbon

Route

Depart

Return

Price

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

lun. 11/17

9:10 am-10:15 am

2 stops20h 05m

Lisbon Humberto Delgado

mié. 12/3

5:00 am-11:59 pm

2 stops23h 59m

$486

CharlestonLisbon

CHS - LIS

CHSLIS

Charleston

mar. 12/9

11:00 am-9:20 am

2 stops17h 20m

Lisbon Humberto Delgado

mar. 12/23

11:20 am-7:32 pm

2 stops37h 12m

$486

CharlestonLisbon

CHS - LIS

CHSLIS

Charleston

dom. 12/7

7:47 pm-10:15 am

1 stop9h 28m

Lisbon Humberto Delgado

mar. 12/23

11:20 am-7:32 pm

2 stops37h 12m

$486

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

lun. 1/12

10:00 am-9:20 am

2 stops42h 20m

Lisbon Humberto Delgado

jue. 1/22

10:55 am-8:47 pm

2 stops38h 52m

$491

CharlestonLisbon

CHS - LIS

CHSLIS

Charleston

mié. 11/5

7:45 pm-10:15 am

1 stop9h 30m

Lisbon Humberto Delgado

vie. 12/5

11:20 am-1:55 pm

2 stops31h 35m

$493

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

mar. 3/10

10:00 am-10:15 am

1 stop20h 15m

Lisbon Humberto Delgado

jue. 3/19

5:00 am-11:59 pm

2 stops22h 59m

$496

SavannahLisbon

SAV - LIS

SAVLIS

Savannah/Hilton Head

mar. 2/17

6:30 am-9:20 am

2 stops21h 50m

Lisbon Humberto Delgado

jue. 3/5

5:00 am-11:26 pm

2 stops23h 26m

$496

ColumbiaLisbon

CAE - LIS

CAELIS

Columbia Metropolitan

mié. 1/14

2:49 pm-8:10 am

2 stops12h 21m

Lisbon Humberto Delgado

vie. 1/23

11:20 am-9:58 pm

2 stops39h 38m

$497

SavannahLisbon

SAV - LIS

SAVLIS

Savannah/Hilton Head

mar. 2/17

7:25 am-8:00 am

1 stop19h 35m

Lisbon Humberto Delgado

jue. 3/5

5:00 am-9:28 pm

2 stops21h 28m

$499

CharlestonLisbon

CHS - LIS

CHSLIS

Charleston

mar. 1/13

12:00 pm-8:00 am

1 stop15h 00m

Lisbon Humberto Delgado

vie. 1/23

5:00 am-5:13 pm

2 stops17h 13m

$499

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 42 results
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Best time to book a flight from South Carolina to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Lisbon

What is the cheapest month to book a flight from South Carolina to Lisbon?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Lisbon (average of $496). Flying from South Carolina to Lisbon in July is currently the most expensive (average of $847). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to LIS?

Find hourly flight availability from South Carolina to Lisbon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Lisbon in the morning. If you’re flexible enough to do this you can expect to save up to 27% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from South Carolina to Lisbon?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Lisbon. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Lisbon flight should consider departing on Tuesday mornings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lisbon from South Carolina?

    Lisbon Humberto Delgado (LIS), located 4.2 mi from the city center, is the airport you fly into when you book flights from South Carolina to Lisbon.

  • How long is the flight from South Carolina to Lisbon?

    There are many flights that can get you from South Carolina to Lisbon in 17h 20m. Fly via United Airlines, Air Canada, or Delta to get the fastest option. There are 3890 mi between South Carolina and Lisbon. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Lisbon one-way?

    One-way options have recently been found by users for as low as $221 on British Airways. Other airlines that offer cheap prices include American Airlines from $266 and Iberia from $288 one-way.

  • What are the most popular routes from South Carolina to Lisbon?

    While some choose either Greenville - Lisbon Humberto Delgado or Charleston - Lisbon Humberto Delgado, Charlotte Douglas - Lisbon Humberto Delgado is the most popular route from South Carolina to Lisbon.

  • Can I find deals for flights from South Carolina to Lisbon that include hotel bookings?

    Yes. In addition to deals on South Carolina to Lisbon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Lisbon.

  • Can I find deals for business class flights from South Carolina to Lisbon?

    Yes. Cheapflights offers flight deals from South Carolina to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Lisbon?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Lisbon (average of $496). Flying from South Carolina to Lisbon in July is currently the most expensive (average of $847). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Sintra
Fátima
Oeiras
Nazaré
Ericeira
Costa da Caparica
Torres Vedras
Beja
Sesimbra
Colares

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Alternative routes for South Carolina to Lisbon

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Lisbon

Discover the top 6 airlines that operate flights from South Carolina to Lisbon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$510Average$960FlexibilityNo cancel feeOn-time69%
DeltaCheapest$530Average$980FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$535Average$989FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$569Average$1,137FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$711Average$1,068FlexibilityNo cancel feeOn-time77%
TAP AIR PORTUGALCheapest$785Average$1,229FlexibilityNo cancel feeOn-timeN/A

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