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Lisbon

$217+ Cheap flights from South Carolina to Lisbon (LIS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LIS
Jan 21 — Jan 281
Wed 1/21
Wed 1/28
1 adult, Economy
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Cheap flight deals from South Carolina to Lisbon

Cheapest flights from South Carolina to Lisbon
Explore the most affordable flight options available from South Carolina to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:44 pmCLT - LIS
1 stop9h 31mLufthansa
Wed 1/146:50 pmLIS - CLT
1 stop27h 05mLufthansa
Deal found 12/21$471
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:44 pmCLT - LIS
1 stop9h 31mMultiple Airlines
Wed 1/143:25 pmLIS - CLT
2 stops30h 30mMultiple Airlines
Deal found 12/21$484
This Virgin Atlantic deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:15 amCLT - LIS
2 stops18h 45mVirgin Atlantic
Wed 1/1410:00 amLIS - CLT
2 stops16h 32mVirgin Atlantic
Deal found 12/21$578
This oojo deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:25 pmCLT - LIS
1 stop29h 40mBritish Airways
Sat 1/106:40 pmLIS - CLT
2 stops32h 05mBritish Airways
Deal found 12/21$659
This Travelocity deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:15 pmCLT - LIS
2 stops36h 35mIberia
Sun 1/116:45 pmLIS - CLT
2 stops30h 49mIberia
Deal found 12/21$671
This oojo deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:25 pmCLT - LIS
1 stop29h 40mBritish Airways
Sun 1/116:40 pmLIS - CLT
2 stops32h 02mBritish Airways
Deal found 12/21$700
This Lufthansa deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:54 pmCLT - LIS
1 stop14h 21mLufthansa
Sun 12/282:10 pmLIS - CLT
1 stop31h 45mLufthansa
Deal found 12/20$787
This Finnair deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:00 pmCLT - LIS
1 stop15h 05mMultiple Airlines
Sat 12/2710:40 amLIS - CLT
1 stop15h 44mMultiple Airlines
Deal found 12/21$829
This oojo deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:25 pmCLT - LIS
1 stop22h 20mBritish Airways
Tue 12/307:40 pmLIS - CLT
1 stop28h 20mBritish Airways
Deal found 12/21$837
This FlightHub deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:50 pmGSP - LIS
1 stop14h 25mLufthansa
Sat 12/2710:15 amLIS - GSP
1 stop18h 34mLufthansa
Deal found 12/21$921
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:55 amGSP - LIS
2 stops17h 20mUnited Airlines
Sat 12/2710:15 amLIS - GSP
2 stops15h 32mUnited Airlines
Deal found 12/21$929
This KAYAK deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:23 amGSP - LIS
1 stop20h 47mBrussels Airlines
Sat 1/1010:15 amLIS - GSP
1 stop29h 53mBrussels Airlines
Deal found 12/21$966

Find flight deals from South Carolina to Lisbon

Keep the following information in mind while searching for South Carolina to Lisbon flight deals. Data was last updated December 22, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$471
(Kiwi.com)

One-way from

$217
(American Airlines)

Popular in

December

Cheapest in

February

Average price

$1,323
Provider with most accurate pricing for Myrtle Beach Intl-Lisbon Humberto Delgado flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Lisbon Humberto Delgado flights.
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From South Carolina to Lisbon Humberto Delgado
Search Deals
One-way flight from South Carolina to Lisbon Humberto Delgado
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from South Carolina to Lisbon that are best for you.

Fly from

South Carolina

Fly to

Lisbon

Route

Depart

Return

Price

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

Mon 1/12

11:49 am-8:10 am

1 stop15h 21m

Lisbon Humberto Delgado

Thu 1/22

11:20 am-11:48 pm

2 stops41h 28m

$486

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

Wed 2/4

10:37 am-7:55 am

2 stops40h 18m

Lisbon Humberto Delgado

Wed 2/11

8:20 am-11:48 pm

2 stops20h 28m

$488

SavannahLisbon

SAV - LIS

SAVLIS

Savannah/Hilton Head

Tue 2/17

9:40 am-8:10 am

2 stops17h 30m

Lisbon Humberto Delgado

Thu 3/5

11:20 am-9:13 pm

2 stops38h 53m

$491

CharlestonLisbon

CHS - LIS

CHSLIS

Charleston

Fri 2/13

10:00 am-8:10 am

2 stops17h 10m

Lisbon Humberto Delgado

Tue 2/17

11:20 am-7:00 pm

2 stops36h 40m

$491

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

Tue 1/20

10:06 am-8:00 am

2 stops16h 54m

Lisbon Humberto Delgado

Wed 1/28

5:00 am-6:47 pm

2 stops18h 47m

$492

ColumbiaLisbon

CAE - LIS

CAELIS

Columbia Metropolitan

Wed 2/4

9:20 am-8:10 am

1 stop17h 50m

Lisbon Humberto Delgado

Wed 2/11

5:00 am-9:18 pm

2 stops21h 18m

$494

CharlestonLisbon

CHS - LIS

CHSLIS

Charleston

Tue 1/13

6:00 am-9:20 am

2 stops22h 20m

Lisbon Humberto Delgado

Fri 1/23

11:20 am-6:04 pm

2 stops35h 44m

$496

ColumbiaLisbon

CAE - LIS

CAELIS

Columbia Metropolitan

Wed 2/4

2:49 pm-8:10 am

2 stops12h 21m

Lisbon Humberto Delgado

Wed 2/11

6:10 am-11:44 pm

2 stops22h 34m

$496

SavannahLisbon

SAV - LIS

SAVLIS

Savannah/Hilton Head

Thu 2/5

7:00 am-8:00 am

1 stop20h 00m

Lisbon Humberto Delgado

Thu 2/12

11:25 am-11:57 pm

2 stops17h 32m

$497

GreenvilleLisbon

GSP - LIS

GSPLIS

Greenville

Mon 1/12

6:20 am-9:20 am

2 stops46h 00m

Lisbon Humberto Delgado

Thu 1/22

11:20 am-11:48 pm

2 stops41h 28m

$498

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 45 results
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Best time to book a flight from South Carolina to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Lisbon

What is the cheapest month to book a flight from South Carolina to Lisbon?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Lisbon (average of $318). Flying from South Carolina to Lisbon in July is currently the most expensive (average of $847). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to LIS?

Find hourly flight availability from South Carolina to Lisbon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 22, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Lisbon in the morning. If you’re flexible enough to do this you can expect to save up to 27% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from South Carolina to Lisbon?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Lisbon. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Lisbon flight should consider departing on Monday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Carolina to Lisbon?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lisbon from South Carolina?

    Lisbon Humberto Delgado (LIS), located 4.2 mi from the city center, is the airport you fly into when you book flights from South Carolina to Lisbon.

  • How long is the flight from South Carolina to Lisbon?

    There are many flights that can get you from South Carolina to Lisbon in 16h 54m. Fly via United Airlines, KLM, or Lufthansa to get the fastest option. There are 3937 mi between South Carolina and Lisbon. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Lisbon?

    While some choose either Greenville - Lisbon Humberto Delgado or Charleston - Lisbon Humberto Delgado, Charlotte Douglas - Lisbon Humberto Delgado is the most popular route from South Carolina to Lisbon.

  • Can I find deals for flights from South Carolina to Lisbon that include hotel bookings?

    Yes. In addition to deals on South Carolina to Lisbon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Lisbon.

  • Can I find deals for business class flights from South Carolina to Lisbon?

    Yes. Cheapflights offers flight deals from South Carolina to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Lisbon?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Lisbon (average of $318). Flying from South Carolina to Lisbon in July is currently the most expensive (average of $847). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Fátima
Oeiras
Ericeira
Costa da Caparica
Torres Vedras
Beja
Nazaré
Sesimbra
Colares

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Alternative routes for South Carolina to Lisbon

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Lisbon

Discover the top 6 airlines that operate flights from South Carolina to Lisbon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$510Average$976FlexibilityNo cancel feeOn-time69%
DeltaCheapest$530Average$980FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$535Average$981FlexibilityNo cancel feeOn-time70%
KLMCheapest$566Average$715FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$569Average$1,152FlexibilityNo cancel feeOn-time71%
TAP AIR PORTUGALCheapest$785Average$1,229FlexibilityNo cancel feeOn-timeN/A

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