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$512+ Cheap flights from Panama City (PTY) to Lisbon (LIS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — LIS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find cheap flights from Panama City to Lisbon with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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3. Compare prices and book

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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Lisbon Humberto Delgado are usually found in March or February, booked 61 days in advance, depart on a Friday or Sunday and return on a Monday

Cheap flight deals from Panama City to Lisbon

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Lisbon (LIS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$765
(KLM)

One-way from

$512
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$828
Provider with most accurate pricing for Panama City Tocumen Intl-Lisbon Humberto Delgado flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Lisbon Humberto Delgado flights.
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From Panama City Tocumen Intl to Lisbon Humberto Delgado
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One-way flight from Panama City Tocumen Intl to Lisbon Humberto Delgado
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Highest demand for flights based on searches. 4% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Panama City to Lisbon

Cheapest flights from Panama City to Lisbon
Explore the most affordable flight options available from Panama City to Lisbon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This KLM deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:45 pmPTY - LIS
1 stop34h 50mMultiple Airlines
Tue 1/135:30 amLIS - PTY
1 stop19h 40mMultiple Airlines
Deal found 10/28$772
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/37:05 pmPTY - LIS
2 stops37h 00mMultiple Airlines
Wed 11/198:05 pmLIS - PTY
1 stop28h 40mMultiple Airlines
Deal found 10/26$836
This KLM deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:45 pmPTY - LIS
1 stop23h 25mMultiple Airlines
Thu 11/205:30 amLIS - PTY
1 stop19h 40mMultiple Airlines
Deal found 10/29$882
This Gotogate deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/39:30 pmPTY - LIS
1 stop12h 45mAir Europa
Wed 11/198:05 pmLIS - PTY
1 stop28h 40mAir Europa
Deal found 10/26$889
This FlightHub deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:45 pmPTY - LIS
1 stop36h 20mTurkish Airlines
Tue 11/1811:30 amLIS - PTY
1 stop37h 20mTurkish Airlines
Deal found 10/29$899
This Expedia deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:20 pmPTY - LIS
1 stop12h 30mIberia
Wed 11/196:30 amLIS - PTY
1 stop15h 15mIberia
Deal found 10/29$912
This KLM deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:45 pmPTY - LIS
1 stop23h 25mMultiple Airlines
Wed 11/196:30 pmLIS - PTY
1 stop30h 40mMultiple Airlines
Deal found 10/29$914
This Air France deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:45 pmPTY - LIS
2 stops17h 45mAir France
Thu 11/205:30 amLIS - PTY
1 stop19h 40mAir France
Deal found 10/29$915
This Turkish Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:45 pmPTY - LIS
1 stop20h 15mTurkish Airlines
Fri 11/2111:40 amLIS - PTY
1 stop37h 10mTurkish Airlines
Deal found 10/29$922

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Lisbon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Panama City to Lisbon that are best for you.

Fly from

Panama City

Fly to

Lisbon

Route

Depart

Return

Price

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Tue 12/30

6:45 pm-10:35 am

1 stop34h 50m

Lisbon Humberto Delgado

Tue 1/13

5:30 am-8:10 pm

1 stop19h 40m

$777

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Sat 2/14

9:45 pm-10:40 am

1 stop31h 55m

Lisbon Humberto Delgado

Sun 3/1

4:05 pm-5:05 pm

2 stops30h 00m

$823

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Sun 3/15

6:45 pm-3:05 pm

1 stop39h 20m

Lisbon Humberto Delgado

Wed 4/15

6:05 am-8:20 pm

1 stop20h 15m

$823

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Sun 2/1

6:45 pm-3:05 pm

1 stop39h 20m

Lisbon Humberto Delgado

Sun 3/1

11:35 am-7:50 pm

1 stop37h 15m

$823

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Wed 2/4

9:45 pm-3:05 pm

1 stop36h 20m

Lisbon Humberto Delgado

Mon 3/9

4:05 pm-5:05 pm

2 stops30h 00m

$823

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Sun 3/15

3:50 pm-5:45 pm

2 stops20h 55m

Lisbon Humberto Delgado

Wed 4/15

6:35 am-8:00 pm

1 stop19h 25m

$873

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Wed 3/11

5:50 pm-5:50 pm

3 stops43h 00m

$519

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Thu 3/12

9:45 am-5:50 pm

3 stops27h 05m

$519

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Sat 3/14

9:45 am-3:00 pm

3 stops24h 15m

$520

Panama CityLisbon

PTY - LIS

PTYLIS

Panama City Tocumen Intl

Mon 12/1

9:30 pm-3:15 pm

1 stop12h 45m

$529

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 14 results
1
2

Compare providers for flights from Panama City to Lisbon

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Lisbon in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Lisbon flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Lisbon flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Lisbon flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Lisbon flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Lisbon flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Lisbon

Have a flexible travel schedule? Discover the best time to fly to Lisbon from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Lisbon

How far ahead should I book a flight from Panama City to Lisbon?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Lisbon. Price data was last updated on October 24, 2025.

Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Lisbon. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Lisbon?

Currently, May is the cheapest month in which you can book a flight from Panama City to Lisbon (average of $625). Flying from Panama City to Lisbon in December is currently the most expensive (average of $858). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Lisbon?

Reviews of airlines servicing Lisbon

Get insights into the airlines that provide service to Lisbon. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lisbon. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Panama City to Lisbon, such as Air Europa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Air Europa
7.0
Good
568 reviews

Crew

7.5

Entertainment

6.6

Food

6.3

Overall

7.0

Boarding

7.1

Comfort

7.0

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.
Air Europa
7.0
Good
568 reviews
Air Europa
7.0
Good
568 reviews

Crew

7.5

Entertainment

6.6

Food

6.3

Overall

7.0

Boarding

7.1

Comfort

7.0

Reviews

1 / 12
6.0
Good

Anonymous,Sep 2025

MAD - JFK

Even though I paid for a ticket that included check in baggage and seat assignment, they did not honor the seat assignment and said it was not included. I paid for 6 tickets, 6 bags so I wanted to ensure we sat together for the long flight. I was given the worst seats possible, very last row, next to the bathroom, and a windowless "window seat". Not what I expected when I made the reservation.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Lisbon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Lisbon?

    Departing from Panama City to Lisbon will take you 31h 55m. Panama City and Lisbon are separated by a distance of 4762 mi.

  • What is the cheapest airline to fly from Panama City to Lisbon round-trip?

    Flying on Air Europa is currently your cheapest option to Lisbon, with prices starting at $717. Air Europa is 20% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to Lisbon that include hotel bookings?

    Yes. In addition to deals on Panama City to Lisbon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Lisbon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Lisbon.

  • Can I find deals for business class flights from Panama City to Lisbon?

    Yes. Cheapflights offers flight deals from Panama City to Lisbon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Lisbon?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Lisbon (average of $625). Flying from Panama City to Lisbon in December is currently the most expensive (average of $858). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lisbon?

Book flights to Lisbon if you plan to visit one of these locations
Sintra
Fátima
Oeiras
Nazaré
Ericeira
Costa da Caparica
Torres Vedras
Beja
Sesimbra
Colares

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Alternative routes for Panama City to Lisbon

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Porto flights

Top airline flying from Panama City to Lisbon

Discover the top airline that operate flights from Panama City to Lisbon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$717Average$1,036FlexibilityNo cancel feeOn-time83%

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