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$377+ Cheap flights from Santiago (SCL) to Lexington (LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — LEX
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Santiago to Lexington

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$815
(Delta)

One-way from

$377
(eDestinos)
From Santiago Arturo Merino Benitez to Lexington Blue Grass
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One-way flight from Santiago Arturo Merino Benitez to Lexington Blue Grass
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Find flight deals from Santiago to Lexington

Cheapest flights from Santiago to Lexington
Explore the most affordable flight options available from Santiago to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:40 pmSCL - LEX
2 stops19h 30mDelta
Sun 11/3010:05 amLEX - SCL
1 stop18h 55mDelta
Deal found 8/11$815
This LATAM Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:15 pmSCL - LEX
1 stop19h 55mLATAM Airlines
Tue 12/93:45 pmLEX - SCL
1 stop13h 15mLATAM Airlines
Deal found 8/10$824

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Santiago to Lexington that are best for you.

Fly from

Santiago

Fly to

Lexington

Route

Depart

Return

Price

SantiagoLexington

SCL - LEX

SCLLEX

Santiago Arturo Merino Benitez

Tue 11/11

12:55 am-5:10 pm

2 stops18h 15m

Lexington Blue Grass

Sun 11/30

11:00 am-6:00 am

2 stops17h 00m

$815

SantiagoLexington

SCL - LEX

SCLLEX

Santiago Arturo Merino Benitez

Sat 11/1

1:35 am-7:45 pm

2 stops19h 10m

$377

SantiagoLexington

SCL - LEX

SCLLEX

Santiago Arturo Merino Benitez

Sun 11/2

11:10 pm-5:12 pm

1 stop20h 02m

$611

SantiagoLexington

SCL - LEX

SCLLEX

Santiago Arturo Merino Benitez

Sun 11/2

6:35 pm-12:18 pm

2 stops19h 43m

$617

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Best time to book a flight from Santiago to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Lexington

What is the cheapest month to book a flight from Santiago to Lexington?

Currently, August is the cheapest month in which you can book a flight from Santiago to Lexington (average of $303). Flying from Santiago to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to Lexington round-trip?

    Our cheapest airline available from Santiago to Lexington is Delta. Our recent data shows that you can find tickets from as low as $815 on this airline. An additional option worth looking into is LATAM Airlines, starting at $824.

  • Can I find deals for flights from Santiago to Lexington that include hotel bookings?

    Yes. In addition to deals on Santiago to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Lexington.

  • Can I find deals for business class flights from Santiago to Lexington?

    Yes. Cheapflights offers flight deals from Santiago to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Lexington?

    Currently, August is the cheapest month in which you can book a flight from Santiago to Lexington (average of $303). Flying from Santiago to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Georgetown
Berea

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