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La Serena

$445+ Cheap flights from Los Angeles (LAX) to La Serena (LSC)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — LSC
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Los Angeles to La Serena

Cheapest flights from Los Angeles to La Serena
Explore the most affordable flight options available from Los Angeles to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This Mytrip deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:00 am
LAX
-
LSC
3 stops34h 26m
Multiple Airlines
Fri 6/1911:25 am
LSC
-
LAX
3 stops38h 27m
Multiple Airlines
Deal found 3/10$982
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:55 pm
LAX
-
LSC
1 stop19h 21m
LATAM Airlines
Tue 5/124:25 pm
LSC
-
LAX
1 stop18h 20m
LATAM Airlines
Deal found 3/8$988
This SmartFares deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:20 pm
LAX
-
LSC
2 stops20h 20m
LATAM Airlines
Tue 4/149:40 am
LSC
-
LAX
2 stops38h 45m
LATAM Airlines
Deal found 3/8$1,004
This KAYAK deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:35 am
LAX
-
LSC
2 stops24h 32m
LATAM Airlines
Fri 6/1910:25 pm
LSC
-
LAX
2 stops59h 35m
LATAM Airlines
Deal found 3/10$1,136

Find flight deals from Los Angeles to La Serena

Discover tips and strategies to find the most affordable flight options for your journey from Los Angeles (LAX) to La Serena (LSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$982
(Mytrip)

One-way from

$445
(Kiwi.com)
Provider with most accurate pricing for Los Angeles Los Angeles-La Serena La Florida flight deals.
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Provider most trusted by Cheapflights users for Los Angeles Los Angeles-La Serena La Florida flights.
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From Los Angeles Los Angeles to La Serena La Florida
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One-way flight from Los Angeles Los Angeles to La Serena La Florida
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Los Angeles to La Serena that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Los Angeles to La Serena that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles Los Angeles

Sat 5/9

3:55 pm-2:16 pm

1 stop19h 21m

La Serena La Florida

Tue 5/12

4:25 pm-7:45 am

1 stop18h 20m

$988

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles Los Angeles

Tue 4/7

9:20 pm-8:40 pm

1 stop20h 20m

La Serena La Florida

Tue 4/14

8:45 pm-6:50 pm

1 stop25h 05m

$1,068
Cheapest one-way

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles Los Angeles

Wed 4/1

11:25 pm-4:39 pm

3 stops37h 14m

$445
Quickest one-way

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles Los Angeles

Wed 4/1

2:55 pm-9:00 am

1 stop14h 05m

$508

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Los Angeles-La Serena flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Los Angeles-La Serena flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Los Angeles-La Serena flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Los Angeles-La Serena flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Los Angeles-La Serena flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Los Angeles to La Serena

Have a flexible travel schedule? Discover the best time to fly to La Serena from Los Angeles with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Los Angeles to La Serena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Los Angeles to La Serena?

    Airlines like LATAM Airlines fly from Los Angeles to La Serena in about 19h 21m. The time it takes to get you to your destination can typically vary by up to . Los Angeles and La Serena are separated by a distance of 5377 mi.

  • Can I find deals for flights from Los Angeles to La Serena that include hotel bookings?

    Yes. In addition to deals on Los Angeles to La Serena flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Los Angeles to La Serena?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Los Angeles to La Serena.

  • Can I find deals for business class flights from Los Angeles to La Serena?

    Yes. Cheapflights offers flight deals from Los Angeles to La Serena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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