$449+ Cheap flights from Missoula to Knoxville (MSO - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — TYS
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missoula to Knoxville
Cheapest
Best
Last-minute
Cheapest flights from Missoula to KnoxvilleExplore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:15 am -
1 stop7h 49m
Tue 11/39:00 am -
1 stop9h 26m
Deal found 10/15![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am -
2 stops9h 39m
Sat 11/710:51 am -
2 stops12h 56m
Deal found 10/19![United Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:45 pm -
1 stop28h 20m
Wed 1/64:09 pm -
2 stops50h 48m
Deal found 10/16![Multiple Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:37 pm -
1 stop5h 55m
Wed 1/64:28 pm -
1 stop7h 24m
Deal found 10/16![United Airlines logo]()
$543
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:38 pm -
1 stop5h 36m
Mon 10/199:00 am -
1 stop6h 32m
Deal found 10/15![United Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:48 pm -
1 stop26h 32m
Mon 10/197:58 pm -
2 stops18h 37m
Deal found 10/15![American Airlines logo]()
$1,039
Best flights from Missoula to KnoxvilleDiscover carefully curated flight deals from Missoula to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Missoula to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am -
1 stop6h 46m
Sat 11/79:00 am -
1 stop6h 31m
Deal found 10/19![United Airlines logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:45 pm -
1 stop28h 20m
Wed 1/64:09 pm -
2 stops50h 48m
Deal found 10/16![Multiple Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:15 am -
1 stop7h 49m
Tue 11/311:59 am -
2 stops11h 48m
Deal found 10/15![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/306:10 am -
1 stop6h 46m
Wed 2/34:28 pm -
1 stop7h 24m
Deal found 10/19![United Airlines logo]()
$499
Last-minute flights from Missoula to KnoxvilleDiscover last-minute flight deals from Missoula to Knoxville. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to Knoxville. Data last updated October 20, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:15 am -
1 stop7h 49m
Tue 11/39:00 am -
1 stop9h 26m
Deal found 10/15![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am -
2 stops9h 39m
Sat 11/710:51 am -
2 stops12h 56m
Deal found 10/19![United Airlines logo]()
$459
This Alaska Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:02 pm -
3 stops19h 59m
Sat 11/75:30 am -
2 stops12h 01m
Deal found 10/19![Alaska Airlines logo]()
$2,204
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:45 pm -
1 stop28h 20m
Wed 1/64:09 pm -
2 stops50h 48m
Deal found 10/16![Multiple Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:37 pm -
1 stop5h 55m
Wed 1/64:28 pm -
1 stop7h 24m
Deal found 10/16![United Airlines logo]()
$543
Find flight deals from Missoula to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $449 (United Airlines) |
Popular in | January |
Cheapest in | July |
Average price | $543 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Missoula to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 11/3
6:15 am-3:01 pm
1 stop6h 46m
Knoxville McGhee Tyson
Sat 11/7
9:00 am-1:31 pm
1 stop6h 31m
$449
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Fri 10/30
6:15 am-4:04 pm
1 stop7h 49m
Knoxville McGhee Tyson
Tue 11/3
11:59 am-9:47 pm
2 stops11h 48m
$454
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Sat 1/30
6:10 am-2:56 pm
1 stop6h 46m
Knoxville McGhee Tyson
Wed 2/3
4:28 pm-9:52 pm
1 stop7h 24m
$499
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 11/24
2:45 pm-9:05 pm
1 stop28h 20m
Knoxville McGhee Tyson
Wed 1/6
4:09 pm-4:57 pm
2 stops50h 48m
$504
Sorted by cheapest first
Compare providers for flights from Missoula to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Missoula to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Missoula-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Missoula-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Missoula-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Missoula-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Missoula to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Missoula with our price prediction graph.
MSO-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 20, 2026.
Read through reviews of airlines operating flights from Missoula to Knoxville, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Crew
8.1
Overall
7.3
Comfort
7.3
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Crew
8.1
Overall
7.3
Comfort
7.3
Food
6.7
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Missoula to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
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Top airline flying from Missoula to Knoxville
Discover the top airline that operate flights from Missoula to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$380 | Average$584 | FlexibilityNo cancel fee | On-time69% |