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$218+ Cheap flights from Missoula to Knoxville (MSO - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — TYS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Missoula to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$332
(United Airlines)

One-way from

$218
(American Airlines)

Popular in

May

Cheapest in

August

Average price

$496
From Missoula Johnson-Bell Field to Knoxville McGhee Tyson
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One-way flight from Missoula Johnson-Bell Field to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 31% potential increase in price ($268 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Missoula to Knoxville

Cheapest flights from Missoula to Knoxville
Explore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/1512:40 pmMSO - TYS
1 stop7h 55mUnited Airlines
lun. 7/217:00 amTYS - MSO
1 stop6h 38mUnited Airlines
Deal found 6/12$332
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/43:27 pmMSO - TYS
1 stop6h 17mDelta
mié. 7/95:12 pmTYS - MSO
2 stops9h 12mDelta
Deal found 6/10$392
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/15:38 amMSO - TYS
1 stop8h 55mAmerican Airlines
mar. 7/86:29 pmTYS - MSO
1 stop7h 00mAmerican Airlines
Deal found 6/10$395
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/210:31 pmMSO - TYS
3 stops19h 34mMultiple Airlines
dom. 7/66:00 amTYS - MSO
2 stops35h 30mMultiple Airlines
Deal found 6/10$638

Cheapflights Fare Finder

Customize your flight search to find flights from Missoula to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Missoula to Knoxville that are best for you.

Fly from

Missoula

Fly to

Knoxville

Route

Depart

Return

Price

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mar. 7/15

12:40 pm-10:35 pm

1 stop7h 55m

Knoxville McGhee Tyson

lun. 7/21

7:00 am-11:38 am

1 stop6h 38m

$332

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

vie. 7/4

3:27 pm-11:44 pm

1 stop6h 17m

Knoxville McGhee Tyson

mié. 7/9

5:12 pm-12:24 am

2 stops9h 12m

$392

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mar. 7/1

5:38 am-4:33 pm

1 stop8h 55m

Knoxville McGhee Tyson

mar. 7/8

6:29 pm-11:29 pm

1 stop7h 00m

$395

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

mié. 7/2

10:31 pm-8:05 pm

3 stops19h 34m

Knoxville McGhee Tyson

dom. 7/6

6:00 am-3:30 pm

2 stops35h 30m

$638

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

vie. 7/11

7:03 am-5:32 pm

1 stop8h 29m

$218

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

vie. 7/11

5:45 am-11:52 pm

2 stops16h 07m

$273

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

vie. 7/11

9:54 pm-3:24 pm

3 stops15h 30m

$376

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Missoula to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Missoula with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to Knoxville

What is the cheapest month to book a flight from Missoula to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Missoula to Knoxville (average of $296). Flying from Missoula to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated junio 12, 2025.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Missoula to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Missoula to Knoxville round-trip?

    Currently priced at $332, United Airlines will fly you from Missoula to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $392 and $395, respectively. These flights start at 44% lower than the current average price 3 months from now.

  • Can I find deals for flights from Missoula to Knoxville that include hotel bookings?

    Yes. In addition to deals on Missoula to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missoula to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to Knoxville.

  • Can I find deals for business class flights from Missoula to Knoxville?

    Yes. Cheapflights offers flight deals from Missoula to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missoula to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Missoula to Knoxville (average of $296). Flying from Missoula to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missoula?

Book flights to Missoula if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 2 airlines flying from Missoula to Knoxville

Discover the top 2 airlines that operate flights from Missoula to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$240Average$418FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$313Average$638FlexibilityNo cancel feeOn-time69%

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