
Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $379 (United Airlines) |
Popular in | January |
Cheapest in | July |
Fly from
Fly to
Route
Depart
Return
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Sat 12/5
6:15 am-8:47 pm
2 stops12h 32m
Knoxville McGhee Tyson
Sun 12/13
6:00 am-1:32 pm
2 stops9h 32m
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Sat 1/30
6:10 am-2:56 pm
1 stop6h 46m
Knoxville McGhee Tyson
Wed 2/3
4:28 pm-9:52 pm
1 stop7h 24m
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Fri 12/4
6:15 am-2:41 pm
1 stop6h 26m
Knoxville McGhee Tyson
Sat 12/12
4:43 pm-9:47 pm
1 stop7h 04m
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Sat 12/5
2:41 pm-10:50 pm
1 stop6h 09m
Knoxville McGhee Tyson
Tue 12/15
4:43 pm-9:47 pm
1 stop7h 04m
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Mon 12/7
6:15 am-2:41 pm
1 stop6h 26m
Knoxville McGhee Tyson
Sun 12/13
6:00 am-1:32 pm
2 stops9h 32m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
Boarding
Food
Comfort
Crew
Entertainment
Overall
Reviews
Asha,Sep 2026
LGA - IAH
Boarding
Food
Comfort
Crew
Entertainment
Overall
Reviews
Asha,Sep 2026
LGA - IAH
Find useful and relevant information for your journey from Missoula to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$380 | Average$584 | FlexibilityNo cancel fee | On-time69% |