$233+ Cheap flights from Missoula to Knoxville (MSO - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — TYS
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Missoula to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider ’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missoula to Knoxville
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Best
One-way
Cheapest flights from Missoula to KnoxvilleExplore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
1 stop8h 13m
Tue 11/37:50 am -
1 stop6h 50m
Deal found 8/16![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:37 pm -
1 stop5h 52m
Tue 11/35:45 am -
2 stops12h 41m
Deal found 8/16![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:23 pm -
2 stops13h 11m
Tue 11/311:50 am -
2 stops13h 01m
Deal found 8/16![Delta logo]()
$470
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:10 pm -
1 stop8h 37m
Sun 11/88:48 pm -
1 stop17h 52m
Deal found 8/21![American Airlines logo]()
$552
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:48 pm -
1 stop8h 11m
Mon 10/265:07 pm -
1 stop21h 28m
Deal found 8/17![American Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:48 pm -
1 stop8h 11m
Thu 10/154:38 pm -
1 stop21h 57m
Deal found 8/18![American Airlines logo]()
$736
This Alaska Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:03 am -
2 stops14h 15m
Sun 11/15:30 am -
2 stops11h 57m
Deal found 8/17![Alaska Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:15 am -
1 stop7h 48m
Sun 11/297:00 am -
2 stops11h 26m
Deal found 8/20![United Airlines logo]()
$796
Best flights from Missoula to KnoxvilleDiscover carefully curated flight deals from Missoula to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Missoula to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:23 pm -
2 stops13h 11m
Tue 11/311:50 am -
2 stops13h 01m
Deal found 8/16![Delta logo]()
$470
This Alaska Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:03 am -
2 stops14h 15m
Sun 11/15:30 am -
2 stops11h 57m
Deal found 8/18![Alaska Airlines logo]()
$761
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:15 am -
1 stop7h 48m
Sun 11/297:00 am -
2 stops11h 26m
Deal found 8/20![United Airlines logo]()
$796
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
1 stop14h 17m
Sun 11/15:05 pm -
1 stop6h 42m
Deal found 8/20![United Airlines logo]()
$857
One-way flights from Missoula to KnoxvilleSearch for one-way flight options from Missoula to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Missoula to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/291:42 pm -
1 stop8h 08m
Deal found 8/19![American Airlines logo]()
$233
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:48 pm -
1 stop8h 11m
Deal found 8/20![American Airlines logo]()
$377
This Priceline deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:03 am -
2 stops12h 42m
Deal found 8/20![Alaska Airlines logo]()
$378
This Alaska Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:01 am -
2 stops14h 40m
Deal found 8/19![Alaska Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:19 pm -
3 stops57h 02m
Deal found 8/20![Allegiant Air logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3010:27 am -
2 stops33h 47m
Deal found 8/19![Multiple Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/281:42 pm -
1 stop8h 08m
Deal found 8/19![American Airlines logo]()
$489
This Alaska Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/287:01 am -
2 stops14h 40m
Deal found 8/19![Alaska Airlines logo]()
$494
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:15 pm -
3 stops23h 44m
Deal found 8/19![Allegiant Air logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/287:51 pm -
3 stops45h 53m
Deal found 8/19![Allegiant Air logo]()
$603
Find flight deals from Missoula to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (American Airlines) |
One-way from | $233 (American Airlines) |
Popular in | January |
Cheapest in | July |
Average price | $713 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Missoula to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 10/27
6:23 pm-9:34 am
2 stops13h 11m
Knoxville McGhee Tyson
Tue 11/3
11:50 am-10:51 pm
2 stops13h 01m
$470
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Thu 10/29
7:03 am-11:18 pm
2 stops14h 15m
Knoxville McGhee Tyson
Sun 11/1
5:30 am-3:27 pm
2 stops11h 57m
$761
Quickest round-trip
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Wed 11/25
6:15 am-4:03 pm
1 stop7h 48m
Knoxville McGhee Tyson
Sun 11/29
7:00 am-4:26 pm
2 stops11h 26m
$796
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Thu 10/29
6:15 am-10:32 pm
1 stop14h 17m
Knoxville McGhee Tyson
Sun 11/1
5:05 pm-9:47 pm
1 stop6h 42m
$857
Cheapest one-way
Quickest one-way
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 12/29
1:42 pm-11:50 pm
1 stop8h 08m
$233
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 10/13
1:48 pm-11:59 pm
1 stop8h 11m
$377
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 10/13
7:03 am-9:45 pm
2 stops12h 42m
$378
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 12/29
7:01 am-11:41 pm
2 stops14h 40m
$384
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Tue 10/13
12:19 pm-11:21 pm
3 stops57h 02m
$444
MissoulaKnoxville
MSO Missoula Johnson-Bell Field - TYS Knoxville McGhee Tyson
MSOTYS
Missoula Johnson-Bell Field
Mon 12/28
1:42 pm-11:50 pm
1 stop8h 08m
$489
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Missoula to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Missoula to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Missoula-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Missoula-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Missoula-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Missoula-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Missoula to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Missoula with our price prediction graph.
MSO-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 21, 2026.
Read through reviews of airlines operating flights from Missoula to Knoxville, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
7.1
Food
6.7
Overall
7.4
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Crew
8.1
Entertainment
7.1
Food
6.7
Overall
7.4
Boarding
7.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Missoula to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
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Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Missoula and Knoxville flights
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Popular flight searches
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Top airline flying from Missoula to Knoxville
Discover the top airline that operate flights from Missoula to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$380 | Average$584 | FlexibilityNo cancel fee | On-time69% |