How long is the flight from Missoula to Knoxville?

Airlines like United Airlines fly from Missoula to Knoxville in about 5h 54m. The time it takes to get you to your destination can typically vary by up to . There are 1724 mi between Missoula and Knoxville.

What are the cheapest airlines flying from Missoula to Knoxville round-trip?

Currently priced at $240, American Airlines will fly you from Missoula to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $360. These flights start at 60% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What is the cheapest time of day to fly from MSO to TYS?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missoula to Knoxville as you normally would.

Most accurate provider : When it comes to deals on Missoula-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Missoula-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Missoula-Knoxville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Missoula-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Missoula to Knoxville that include hotel bookings?

Yes. In addition to deals on Missoula to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missoula to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to Knoxville.

Can I find deals for business class flights from Missoula to Knoxville?

Yes. Cheapflights offers flight deals from Missoula to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$291+ Flights from Missoula to Knoxville

Q: How much does it cost to fly round-trip from Missoula to Knoxville?

Airfare is below average for this route at the moment. Missoula to Knoxville flights typically cost between $599 and $916 in January. The cheapest round-trip price found within the last 3 days was $399 on United Airlines (Jan 10-Jan 13).

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Cheap flight deals from Missoula to Knoxville

Cheapest flights from Missoula to Knoxville
Explore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

Wed 12/312:38 pmMSO - TYS

1 stop5h 51mUnited Airlines

Tue 1/611:10 amTYS - MSO

2 stops12h 41mUnited Airlines

Deal found 12/15

$645

Best flights from Missoula to Knoxville
Discover carefully curated flight deals from Missoula to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 16, 2025.

Sat 1/102:37 pmMSO - TYS

1 stop5h 54mUnited Airlines

Tue 1/138:45 amTYS - MSO

1 stop6h 50mUnited Airlines

Deal found 12/14

$399

Thu 1/15:15 pmMSO - TYS

2 stops19h 33mUnited Airlines

Mon 1/54:04 pmTYS - MSO

1 stop7h 37mUnited Airlines

Deal found 12/15

$637

Wed 12/312:38 pmMSO - TYS

1 stop5h 51mUnited Airlines

Tue 1/611:10 amTYS - MSO

2 stops12h 41mUnited Airlines

Deal found 12/15

$645

Fri 1/25:15 pmMSO - TYS

2 stops21h 45mUnited Airlines

Wed 1/74:25 pmTYS - MSO

1 stop7h 26mUnited Airlines

Deal found 12/15

$736

Last-minute flights from Missoula to Knoxville
Discover last-minute flight deals from Missoula to Knoxville. Data last updated December 16, 2025 and is based on user searches.

Wed 12/312:38 pmMSO - TYS

1 stop5h 51mUnited Airlines

Tue 1/611:10 amTYS - MSO

2 stops12h 41mUnited Airlines

Deal found 12/15

$645

Thu 1/15:15 pmMSO - TYS

2 stops19h 33mUnited Airlines

Mon 1/55:45 amTYS - MSO

2 stops12h 25mUnited Airlines

Deal found 12/15

$543

Fri 1/22:38 pmMSO - TYS

3 stops27h 12mUnited Airlines

Wed 1/74:25 pmTYS - MSO

1 stop7h 26mUnited Airlines

Deal found 12/15

$733

Fri 1/27:00 amMSO - TYS

1 stop8h 30mAmerican Airlines

Wed 1/77:54 amTYS - MSO

1 stop6h 56mAmerican Airlines

Deal found 12/15

$759

Sat 1/102:37 pmMSO - TYS

1 stop5h 54mUnited Airlines

Tue 1/134:25 pmTYS - MSO

1 stop7h 26mUnited Airlines

Deal found 12/15

$399

One-way flights from Missoula to Knoxville
Search for one-way flight options from Missoula to Knoxville. Find affordable one-way fares based on user searches. Data last updated December 16, 2025.

Sun 2/157:00 amMSO - TYS

1 stop8h 33mAmerican Airlines

Deal found 12/15

$291

Sun 2/156:15 amMSO - TYS

2 stops12h 42mUnited Airlines

Deal found 12/14

$341

Find flight deals from Missoula to Knoxville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$399 (United Airlines)
One-way from	$291 (American Airlines)
Popular in	May
Cheapest in	August
Average price	$708

Provider with most accurate pricing for Missoula Johnson-Bell Field-Knoxville McGhee Tyson flight deals.

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Provider most trusted by Cheapflights users for Missoula Johnson-Bell Field-Knoxville McGhee Tyson flights.

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From Missoula Johnson-Bell Field to Knoxville McGhee Tyson

Search Deals

One-way flight from Missoula Johnson-Bell Field to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 30% potential increase in price ($259 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 13% potential price decrease ($70 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missoula to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

Sat 1/10

2:37 pm-10:31 pm

1 stop5h 54m

Knoxville McGhee Tyson

Tue 1/13

8:45 am-1:35 pm

1 stop6h 50m

$399

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

Thu 1/1

5:15 pm-2:48 pm

2 stops19h 33m

Knoxville McGhee Tyson

Mon 1/5

4:04 pm-9:41 pm

1 stop7h 37m

$637

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

Wed 12/31

2:38 pm-10:29 pm

1 stop5h 51m

Knoxville McGhee Tyson

Tue 1/6

11:10 am-9:51 pm

2 stops12h 41m

$645

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

Fri 1/2

5:15 pm-5:00 pm

2 stops21h 45m

Knoxville McGhee Tyson

Wed 1/7

4:25 pm-9:51 pm

1 stop7h 26m

$736

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

Sun 2/15

7:00 am-5:33 pm

1 stop8h 33m

$291

MissoulaKnoxville

MSO - TYS

MSOTYS

Missoula Johnson-Bell Field

Sun 2/15

6:15 am-8:57 pm

2 stops12h 42m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Compare providers for flights from Missoula to Knoxville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Missoula to Knoxville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Missoula-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Missoula-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Missoula-Knoxville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Missoula-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Missoula to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Missoula with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missoula to Knoxville

How much does it cost to fly round-trip from Missoula to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Missoula to Knoxville, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

United Airlines

7.4

Good

9,092 reviews

Reviews

1 / 20

10.0

Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

United Airlines

7.4

Good

9,092 reviews

United Airlines

7.4

Good

9,092 reviews

Reviews

1 / 20

10.0

Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

American Airlines

7.2

Good

11,049 reviews

United Airlines

7.4

Good

9,092 reviews

Reviews

1 / 20

10.0

Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

How long is the flight from Missoula to Knoxville?
Airlines like United Airlines fly from Missoula to Knoxville in about 5h 54m. The time it takes to get you to your destination can typically vary by up to . There are 1724 mi between Missoula and Knoxville.
What are the cheapest airlines flying from Missoula to Knoxville round-trip?
Currently priced at $240, American Airlines will fly you from Missoula to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $360. These flights start at 60% lower than the current average price 3 months from now.
Can I find deals for flights from Missoula to Knoxville that include hotel bookings?
Yes. In addition to deals on Missoula to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missoula to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missoula to Knoxville.
Can I find deals for business class flights from Missoula to Knoxville?
Yes. Cheapflights offers flight deals from Missoula to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Missoula to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$240	Average$418	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$360	Average$692	FlexibilityNo cancel fee	On-time69%

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$291+ Cheap flights from Missoula to Knoxville (MSO - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missoula to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missoula to Knoxville

Cheapest flights from Missoula to KnoxvilleExplore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

Explore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

Find flight deals from Missoula to Knoxville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missoula to Knoxville that are best for you.

Compare providers for flights from Missoula to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Missoula to Knoxville in December.

Best time to book a flight from Missoula to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Missoula with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missoula to Knoxville

How much does it cost to fly round-trip from Missoula to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Missoula to Knoxville, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missoula to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missoula to Knoxville?

What are the cheapest airlines flying from Missoula to Knoxville round-trip?

Can I find deals for flights from Missoula to Knoxville that include hotel bookings?

How can I find direct flights from Missoula to Knoxville?

Can I find deals for business class flights from Missoula to Knoxville?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missoula to Knoxville

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Top 2 airlines flying from Missoula to Knoxville

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Cheapest flights from Missoula to Knoxville
Explore the most affordable flight options available from Missoula to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.