$38+ Cheap flights from Spartanburg, SC to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — MIA
Feb 11 — Feb 181
1 adult, Economy
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Find cheap flights from Spartanburg to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Spartanburg to Key Largo are usually found in February or September, booked 65 days in advance, depart on a Friday or Thursday and return on a Friday
Cheap flight deals from Spartanburg to Key Largo
Keep the following information in mind while searching for Spartanburg to Key Largo flight deals. Data was last updated January 12, 2026.
Most accurate provider | Mytrip 3 stars |
|---|---|
Most trusted provider | Mytrip 3 stars |
Round-trip from | $81 (Kiwi.com) |
One-way from | $38 (CheapOair) |
Popular in | November |
Cheapest in | February |
Average price | $173 |
Find flight deals from Spartanburg to Key Largo
Cheapest flights from Spartanburg to Key LargoExplore the most affordable flight options available from Spartanburg to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.
Explore the most affordable flight options available from Spartanburg to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3011:33 am
CLT
- MIA
Nonstop2h 21m
Multiple Airlines
Mon 2/210:06 am
MIA
- CLT
Nonstop2h 16m
Multiple Airlines
Deal found 1/10![Multiple Airlines logo]()
$81
This Frontier deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/228:38 pm
CLT
- MIA
Nonstop2h 17m
Frontier
Fri 1/308:15 am
MIA
- CLT
Nonstop2h 23m
Frontier
Deal found 1/11![Frontier logo]()
$83
This CheapOair deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/228:38 pm
CLT
- MIA
Nonstop2h 17m
Frontier
Thu 1/298:00 am
MIA
- CLT
Nonstop2h 23m
Frontier
Deal found 1/10![Frontier logo]()
$84
This CheapOair deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/227:00 am
CLT
- MIA
Nonstop2h 10m
Spirit Airlines
Thu 1/2910:06 am
MIA
- CLT
Nonstop2h 16m
Spirit Airlines
Deal found 1/11![Spirit Airlines logo]()
$85
This Super.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:27 pm
CLT
- MIA
Nonstop2h 16m
Frontier
Fri 3/67:30 am
MIA
- CLT
Nonstop2h 17m
Frontier
Deal found 1/10![Frontier logo]()
$86
This Super.com deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/267:00 am
CLT
- MIA
Nonstop2h 10m
Spirit Airlines
Sun 2/110:06 am
MIA
- CLT
Nonstop2h 16m
Spirit Airlines
Deal found 1/11![Spirit Airlines logo]()
$88
This Priceline deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/273:15 pm
CLT
- MIA
1 stop8h 44m
Multiple Airlines
Fri 1/308:15 am
MIA
- CLT
Nonstop2h 23m
Multiple Airlines
Deal found 1/9![Multiple Airlines logo]()
$89
This CheapOair deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/228:38 pm
CLT
- MIA
Nonstop2h 17m
Frontier
Mon 1/263:16 pm
MIA
- CLT
Nonstop2h 20m
Frontier
Deal found 1/11![Frontier logo]()
$90
This Priceline deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/93:15 pm
CLT
- MIA
1 stop8h 44m
Multiple Airlines
Fri 2/1312:55 pm
MIA
- CLT
Nonstop2h 30m
Multiple Airlines
Deal found 1/11![Multiple Airlines logo]()
$92
This Cheapflightsfares deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:00 am
CLT
- MIA
Nonstop2h 10m
Spirit Airlines
Sun 3/110:05 am
MIA
- CLT
Nonstop2h 15m
Spirit Airlines
Deal found 1/10![Spirit Airlines logo]()
$93
This Super.com deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/73:15 pm
CLT
- MIA
1 stop8h 44m
Spirit Airlines
Mon 2/910:06 am
MIA
- CLT
Nonstop2h 16m
Spirit Airlines
Deal found 1/11![Spirit Airlines logo]()
$94
Cheapflights Fare Finder
Customize your flight search to find flights from Spartanburg to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Spartanburg to Key Largo that are best for you.
Fly from
Spartanburg
Fly to
Key Largo
Route
Depart
Return
Price
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 2/21
1:10 pm-10:15 pm
2 stops9h 05m
Miami
Fri 2/27
7:25 am-12:15 pm
1 stop4h 50m
$254
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 2/21
3:20 pm-10:30 pm
1 stop7h 10m
Miami
Sat 2/28
6:35 am-12:35 pm
2 stops6h 00m
$254
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Mon 3/2
10:55 am-10:25 pm
2 stops11h 30m
Miami
Tue 3/3
6:55 am-7:55 pm
2 stops13h 00m
$305
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Tue 2/3
5:25 am-9:24 am
1 stop3h 59m
Miami
Tue 2/10
1:21 pm-7:09 pm
1 stop5h 48m
$310
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 2/7
1:13 pm-5:17 pm
1 stop4h 04m
Miami
Tue 2/10
10:29 am-4:02 pm
1 stop5h 33m
$310
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Wed 2/4
7:59 am-12:14 pm
1 stop4h 15m
Miami
Wed 2/11
1:21 pm-7:09 pm
1 stop5h 48m
$310
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 2/28
10:45 am-9:45 pm
2 stops11h 00m
Miami
Sat 3/7
10:35 am-6:30 pm
1 stop7h 55m
$319
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 2/7
1:05 pm-8:40 pm
2 stops7h 35m
Miami
Sat 2/14
6:35 am-12:35 pm
2 stops6h 00m
$324
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Wed 2/18
8:25 am-8:05 pm
2 stops11h 40m
Miami
Sat 2/21
6:35 am-12:35 pm
2 stops6h 00m
$342
CharlotteMiami
CLT - MIA
CLTMIA
Charlotte Douglas
Sat 2/7
7:55 am-7:05 pm
2 stops11h 10m
Miami
Mon 2/9
7:00 am-5:40 pm
1 stop10h 40m
$357
Showing 1-10 of 23 results
Best time to book a flight from Spartanburg to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Spartanburg to Key Largo
How far ahead should I book a flight from Spartanburg to Key Largo?
Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Key Largo. Price data was last updated on January 9, 2026.
Booking 65 days in advance of your planned departure date is, on average, the best time to get cheap flights from Spartanburg to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Spartanburg to Key Largo?
Currently, September is the cheapest month in which you can book a flight from Spartanburg to Key Largo (average of $36). Flying from Spartanburg to Key Largo in July is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SB1 to KE9?
Find hourly flight availability from Spartanburg to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 12, 2026.
One of the essential ways to save on airfare from Spartanburg to Key Largo is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.
What is the cheapest day to fly from Spartanburg to Key Largo?
Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Key Largo. Price data was last updated on January 10, 2026.
Travelers seeking maximum savings on their Spartanburg to Key Largo flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Spartanburg to Key Largo
Explore weekly flight availability from Spartanburg to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 12, 2026.
The most flights from SB1 to KE9 are scheduled on a Monday (28 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (23 on average).
How much does it cost to fly round-trip from Spartanburg to Key Largo?
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated January 12, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Spartanburg to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Spartanburg to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Spartanburg to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Top 7 airlines flying from Spartanburg to Key Largo
Discover the top 7 airlines that operate flights from Spartanburg to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$59 | Average$179 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$67 | Average$146 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$70 | Average$175 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$174 | Average$384 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$180 | Average$429 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$222 | Average$390 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$319 | Average$515 | FlexibilityNo cancel fee | On-time69% |