Key Largo

$38+ Cheap flights from Spartanburg, SC to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — MIA
Feb 11 — Feb 181
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Spartanburg to Key Largo are usually found in February or September, booked 65 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Spartanburg to Key Largo

Keep the following information in mind while searching for Spartanburg to Key Largo flight deals. Data was last updated January 12, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$81
(Kiwi.com)

One-way from

$38
(CheapOair)

Popular in

November

Cheapest in

February

Average price

$173
Provider with most accurate pricing for Charlotte Douglas-Miami flight deals.
Provider most trusted by Cheapflights users for Charlotte Douglas-Miami flights.
From Spartanburg to Key Largo
One-way flight from Spartanburg to Key Largo
Highest demand for flights based on searches. 13% potential increase in price ($32 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Find flight deals from Spartanburg to Key Largo

Cheapest flights from Spartanburg to Key Largo
Explore the most affordable flight options available from Spartanburg to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3011:33 am
CLT
-
MIA
Nonstop2h 21m
Multiple Airlines
Mon 2/210:06 am
MIA
-
CLT
Nonstop2h 16m
Multiple Airlines
Deal found 1/10$81
This Frontier deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/228:38 pm
CLT
-
MIA
Nonstop2h 17m
Frontier
Fri 1/308:15 am
MIA
-
CLT
Nonstop2h 23m
Frontier
Deal found 1/11$83
This CheapOair deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/228:38 pm
CLT
-
MIA
Nonstop2h 17m
Frontier
Thu 1/298:00 am
MIA
-
CLT
Nonstop2h 23m
Frontier
Deal found 1/10$84
This CheapOair deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/227:00 am
CLT
-
MIA
Nonstop2h 10m
Spirit Airlines
Thu 1/2910:06 am
MIA
-
CLT
Nonstop2h 16m
Spirit Airlines
Deal found 1/11$85
This Super.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:27 pm
CLT
-
MIA
Nonstop2h 16m
Frontier
Fri 3/67:30 am
MIA
-
CLT
Nonstop2h 17m
Frontier
Deal found 1/10$86
This Super.com deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/267:00 am
CLT
-
MIA
Nonstop2h 10m
Spirit Airlines
Sun 2/110:06 am
MIA
-
CLT
Nonstop2h 16m
Spirit Airlines
Deal found 1/11$88
This Priceline deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/273:15 pm
CLT
-
MIA
1 stop8h 44m
Multiple Airlines
Fri 1/308:15 am
MIA
-
CLT
Nonstop2h 23m
Multiple Airlines
Deal found 1/9$89
This CheapOair deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/228:38 pm
CLT
-
MIA
Nonstop2h 17m
Frontier
Mon 1/263:16 pm
MIA
-
CLT
Nonstop2h 20m
Frontier
Deal found 1/11$90
This Priceline deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/93:15 pm
CLT
-
MIA
1 stop8h 44m
Multiple Airlines
Fri 2/1312:55 pm
MIA
-
CLT
Nonstop2h 30m
Multiple Airlines
Deal found 1/11$92
This Cheapflightsfares deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:00 am
CLT
-
MIA
Nonstop2h 10m
Spirit Airlines
Sun 3/110:05 am
MIA
-
CLT
Nonstop2h 15m
Spirit Airlines
Deal found 1/10$93
This Super.com deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/73:15 pm
CLT
-
MIA
1 stop8h 44m
Spirit Airlines
Mon 2/910:06 am
MIA
-
CLT
Nonstop2h 16m
Spirit Airlines
Deal found 1/11$94

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Spartanburg to Key Largo that are best for you.

Fly from

Spartanburg

Fly to

Key Largo

Route

Depart

Return

Price

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 2/21

1:10 pm-10:15 pm

2 stops9h 05m

Miami

Fri 2/27

7:25 am-12:15 pm

1 stop4h 50m

$254

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 2/21

3:20 pm-10:30 pm

1 stop7h 10m

Miami

Sat 2/28

6:35 am-12:35 pm

2 stops6h 00m

$254

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Mon 3/2

10:55 am-10:25 pm

2 stops11h 30m

Miami

Tue 3/3

6:55 am-7:55 pm

2 stops13h 00m

$305

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Tue 2/3

5:25 am-9:24 am

1 stop3h 59m

Miami

Tue 2/10

1:21 pm-7:09 pm

1 stop5h 48m

$310

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 2/7

1:13 pm-5:17 pm

1 stop4h 04m

Miami

Tue 2/10

10:29 am-4:02 pm

1 stop5h 33m

$310

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Wed 2/4

7:59 am-12:14 pm

1 stop4h 15m

Miami

Wed 2/11

1:21 pm-7:09 pm

1 stop5h 48m

$310

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 2/28

10:45 am-9:45 pm

2 stops11h 00m

Miami

Sat 3/7

10:35 am-6:30 pm

1 stop7h 55m

$319

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 2/7

1:05 pm-8:40 pm

2 stops7h 35m

Miami

Sat 2/14

6:35 am-12:35 pm

2 stops6h 00m

$324

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Wed 2/18

8:25 am-8:05 pm

2 stops11h 40m

Miami

Sat 2/21

6:35 am-12:35 pm

2 stops6h 00m

$342

CharlotteMiami

CLT - MIA

CLTMIA

Charlotte Douglas

Sat 2/7

7:55 am-7:05 pm

2 stops11h 10m

Miami

Mon 2/9

7:00 am-5:40 pm

1 stop10h 40m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 23 results
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Best time to book a flight from Spartanburg to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Key Largo

How far ahead should I book a flight from Spartanburg to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Key Largo. Price data was last updated on January 9, 2026.

Booking 65 days in advance of your planned departure date is, on average, the best time to get cheap flights from Spartanburg to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Spartanburg to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Spartanburg to Key Largo (average of $36). Flying from Spartanburg to Key Largo in July is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to KE9?

Find hourly flight availability from Spartanburg to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 12, 2026.

One of the essential ways to save on airfare from Spartanburg to Key Largo is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

What is the cheapest day to fly from Spartanburg to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Key Largo. Price data was last updated on January 10, 2026.

Travelers seeking maximum savings on their Spartanburg to Key Largo flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Spartanburg to Key Largo

Explore weekly flight availability from Spartanburg to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 12, 2026.

The most flights from SB1 to KE9 are scheduled on a Monday (28 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (23 on average).

How much does it cost to fly round-trip from Spartanburg to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated January 12, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Spartanburg to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Spartanburg to Key Largo flight route?

  • How long is the flight from Spartanburg to Key Largo?

    For as low as $310, Southwest can have you in Key Largo from Spartanburg in 3h 59m. The distance between Spartanburg and Key Largo is about 652 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Spartanburg to Key Largo one-way?

    One-way options have recently been found by users for as low as $38 on Allegiant Air. Other airlines that offer cheap prices include Spirit Airlines from $39 and Frontier from $39 one-way.

  • What are the most reliable airlines from Spartanburg to Key Largo?

    Before booking your flight to Key Largo from Spartanburg, check out the most reliable airlines to get you to your destination on time: Finnair (85%), GOL (81%), British Airways( 80%).

  • What are the cheapest flights from Spartanburg to Key Largo?

    Looking for the cheapest flight from Spartanburg to Key Largo? While on average our users pay $303, our data indicates the cheapest price to be $40. The most popular route (Charlotte Douglas - Miami), is priced around $63.

  • Can I find deals for flights from Spartanburg to Key Largo that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Key Largo.

  • Can I find deals for business class flights from Spartanburg to Key Largo?

    Yes. Cheapflights offers flight deals from Spartanburg to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Spartanburg to Key Largo (average of $36). Flying from Spartanburg to Key Largo in July is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Spartanburg to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Spartanburg to Key Largo

Discover the top 7 airlines that operate flights from Spartanburg to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$59Average$179FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$67Average$146FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$70Average$175FlexibilityNo cancel feeOn-time65%
DeltaCheapest$174Average$384FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$180Average$429FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$222Average$390FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$319Average$515FlexibilityNo cancel feeOn-time69%

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