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Key Largo

$99+ Cheap flights from Greenville (GSP) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MIA
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheapflights Tip: The best prices from Greenville to Key Largo are usually found in September or July, booked 26 days in advance, depart on a Friday or Saturday and return on a Monday

Cheap flight deals from Greenville to Key Largo

Cheapest flights from Greenville to Key Largo
Explore the most affordable flight options available from Greenville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:07 pmGSP - MIA
Nonstop1h 58mAmerican Airlines
Wed 1/284:26 pmMIA - GSP
Nonstop2h 00mAmerican Airlines
Deal found 12/15$314
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:59 pmGSP - MIA
1 stop4h 47mDelta
Wed 1/283:25 pmMIA - GSP
1 stop6h 27mDelta
Deal found 12/15$334
This Southwest deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:15 pmGSP - MIA
1 stop6h 10mSouthwest
Wed 1/287:15 amMIA - GSP
2 stops10h 20mSouthwest
Deal found 12/15$395
This Mytrip deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:41 pmGSP - MIA
2 stops23h 23mMultiple Airlines
Wed 1/289:26 pmMIA - GSP
2 stops19h 29mMultiple Airlines
Deal found 12/15$404
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:04 pmGSP - MIA
Nonstop1h 59mAmerican Airlines
Sat 1/310:49 pmMIA - GSP
Nonstop2h 02mAmerican Airlines
Deal found 12/16$421
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:40 amGSP - MIA
2 stops15h 20mSouthwest
Thu 12/257:40 amMIA - GSP
1 stop8h 25mSouthwest
Deal found 12/14$446
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:07 pmGSP - MIA
Nonstop1h 58mAmerican Airlines
Sat 12/275:32 pmMIA - GSP
Nonstop2h 02mAmerican Airlines
Deal found 12/14$449

Find flight deals from Greenville to Key Largo

Keep the following information in mind while searching for Greenville to Key Largo flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$179
(American Airlines)

One-way from

$99
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$450
Provider with most accurate pricing for Greenville-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Miami flights.
Search Deals
From Greenville to Key Largo
Search Deals
One-way flight from Greenville to Key Largo
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Greenville to Key Largo that are best for you.

Fly from

Greenville

Fly to

Key Largo

Route

Depart

Return

Price

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Fri 1/16

6:56 pm-8:59 pm

Nonstop2h 03m

Miami

Tue 1/20

9:50 pm-11:57 pm

Nonstop2h 07m

$229

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 1/13

7:03 am-12:48 pm

1 stop5h 45m

Miami

Tue 1/20

9:50 pm-11:57 pm

Nonstop2h 07m

$234

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Mon 1/26

10:05 am-4:10 pm

1 stop6h 05m

Miami

Fri 1/30

7:55 am-5:35 pm

1 stop9h 40m

$249

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 1/13

3:05 pm-7:46 pm

1 stop4h 41m

Miami

Tue 1/20

5:50 am-11:03 am

1 stop5h 13m

$262

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Fri 1/30

3:39 pm-10:22 pm

1 stop6h 43m

Miami

Sat 2/7

7:07 am-1:19 pm

1 stop6h 12m

$294

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Thu 2/5

10:32 am-3:21 pm

1 stop4h 49m

Miami

Mon 2/9

7:07 am-11:24 am

1 stop4h 17m

$299

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Thu 1/29

11:15 am-10:00 pm

2 stops10h 45m

Miami

Mon 2/2

7:15 am-5:35 pm

2 stops10h 20m

$309

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 1/6

10:05 am-4:10 pm

1 stop6h 05m

Miami

Thu 1/8

7:15 am-5:35 pm

2 stops10h 20m

$331

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Sat 1/10

10:50 am-7:05 pm

1 stop8h 15m

Miami

Mon 1/12

7:15 am-5:35 pm

2 stops10h 20m

$332

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 1/13

11:15 am-8:05 pm

1 stop8h 50m

$105

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 17 results
1
2

Best time to book a flight from Greenville to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Key Largo

How far ahead should I book a flight from Greenville to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Key Largo. Price data was last updated on December 12, 2025.

Booking 26 days in advance of your planned departure date is, on average, the best time to get cheap flights from Greenville to Key Largo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Greenville to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Greenville to Key Largo (average of $36). Flying from Greenville to Key Largo in April is currently the most expensive (average of $78). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to KE9?

Find hourly flight availability from Greenville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

One of the essential ways to save on airfare from Greenville to Key Largo is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 48% on airfare.

What is the cheapest day to fly from Greenville to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Greenville to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Greenville to Key Largo flight should consider departing on Sunday at noon when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated December 16, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,010 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,047 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Allegiant Air
7.2
Good
700 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Overall

7.9

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Greenville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Key Largo?

    Greenville (GSP) is the airport you will fly out of if you book a flight from Greenville to Key Largo. You should not have trouble finding flights to Key Largo from Greenville; the airport handles an average of 1 outbound flight to Key Largo per day. You should also have plenty of airline options to choose from since 4 airlines have flights from the Greenville airport to Key Largo. It is only a 10.4 mi journey to Greenville (GSP) from Greenville’s city center.

  • How popular is this Greenville to Key Largo flight route?

    The Greenville to Key Largo flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Greenville to Key Largo?

    Departing from Greenville to Key Largo will take you 2h 03m. There are 639 mi between Greenville and Key Largo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Key Largo one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $39. Users have also found prices from $118 and $125 on Southwest and American Airlines, respectively.

  • What are the most reliable airlines from Greenville to Key Largo?

    Consider Finnair (100%), Envoy Air (95%) or Qatar Airways (94%) when booking your flight. These represent the most reliable airlines when flying from Greenville to Key Largo.

  • What are the cheapest flights from Greenville to Key Largo?

    The cheapest flight price from Greenville to Key Largo is $125. On average you can expect to pay $483. The most popular route, (Greenville - Miami), can usually be booked for $249.

  • Can I find deals for flights from Greenville to Key Largo that include hotel bookings?

    Yes. In addition to deals on Greenville to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Key Largo.

  • Can I find deals for business class flights from Greenville to Key Largo?

    Yes. Cheapflights offers flight deals from Greenville to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Greenville to Key Largo (average of $36). Flying from Greenville to Key Largo in April is currently the most expensive (average of $78). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Greenville to Key Largo

Discover the top 4 airlines that operate flights from Greenville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$85Average$169FlexibilityNo cancel feeOn-time88%
DeltaCheapest$183Average$394FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$222Average$390FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$253Average$410FlexibilityNo cancel feeOn-time71%

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