HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$655+ Cheap flights from Panama City, FL (ECP) to Italy

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — NAP
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated July 2, 2025.

Round-trip from

$717
(American Airlines)

One-way from

$709
(United Airlines)

Popular in

May

Cheapest in

November

Average price

$1,218
From Panama City NW Florida Beaches to Italy
Search Deals
One-way flight from Panama City NW Florida Beaches to Italy
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($313 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($76 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This KLM deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/39:23 amECP - FCO
1 stop18h 07mKLM
Mon 11/1010:15 amFCO - ECP
1 stop14h 38mKLM
Deal found 6/30$655
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/311:15 amECP - FCO
1 stop16h 15mDelta
Mon 11/109:20 amFCO - ECP
2 stops20h 23mDelta
Deal found 6/30$660
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/33:00 pmECP - FCO
2 stops37h 05mUnited Airlines
Mon 11/1011:00 amFCO - ECP
2 stops33h 57mUnited Airlines
Deal found 6/29$672
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/111:19 pmECP - FCO
1 stop15h 01mAmerican Airlines
Wed 8/2012:10 pmFCO - ECP
1 stop28h 28mAmerican Airlines
Deal found 7/1$717
This Gurufare deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/144:49 pmECP - FCO
2 stops35h 16mScandinavian Airlines
Thu 8/2111:55 amFCO - ECP
2 stops42h 11mScandinavian Airlines
Deal found 6/30$767
This KLM deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/91:53 pmECP - VCE
1 stop14h 42mKLM
Fri 9/2611:15 amVCE - ECP
1 stop15h 32mKLM
Deal found 6/30$770
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:02 pmECP - VCE
1 stop11h 33mDelta
Fri 9/261:30 pmVCE - ECP
2 stops25h 38mDelta
Deal found 6/30$775
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:30 amECP - VCE
2 stops20h 10mUnited Airlines
Sat 8/239:40 amVCE - ECP
2 stops31h 14mUnited Airlines
Deal found 7/2$805
This Air France deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/149:13 amECP - FCO
1 stop18h 52mMultiple Airlines
Sat 10/410:00 amFCO - ECP
2 stops16h 47mMultiple Airlines
Deal found 7/1$1,042
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/912:01 pmECP - VCE
2 stops16h 24mAmerican Airlines
Fri 9/266:25 amVCE - ECP
3 stops18h 11mAmerican Airlines
Deal found 6/30$4,211
This Air France deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/911:15 amECP - VCE
1 stop17h 20mMultiple Airlines
Sun 10/199:25 amVCE - ECP
2 stops17h 13mMultiple Airlines
Deal found 6/30$4,397

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 11/3

11:15 am-10:30 am

1 stop16h 15m

Rome Fiumicino

Mon 11/10

12:45 pm-10:43 pm

1 stop16h 58m

$655

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 11/3

11:15 am-10:30 am

1 stop16h 15m

Rome Fiumicino

Mon 11/10

9:20 am-10:43 pm

2 stops20h 23m

$660

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 11/3

3:00 pm-11:05 am

2 stops37h 05m

Rome Fiumicino

Mon 11/10

11:00 am-1:57 pm

2 stops33h 57m

$672

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 8/11

1:19 pm-11:20 am

1 stop15h 01m

Rome Fiumicino

Wed 8/20

12:10 pm-9:38 am

1 stop28h 28m

$717

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Thu 8/14

4:49 pm-11:05 am

2 stops35h 16m

Rome Fiumicino

Thu 8/21

11:55 am-11:06 pm

2 stops42h 11m

$767

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Tue 9/9

1:53 pm-11:35 am

1 stop14h 42m

Venice Marco Polo

Fri 9/26

11:15 am-7:47 pm

1 stop15h 32m

$770

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Tue 9/9

5:02 pm-11:35 am

1 stop11h 33m

Venice Marco Polo

Fri 9/26

1:30 pm-8:08 am

2 stops25h 38m

$775

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Sat 8/16

6:30 am-9:40 am

2 stops20h 10m

Venice Marco Polo

Sat 8/23

9:40 am-9:54 am

2 stops31h 14m

$805

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 9/14

9:13 am-11:05 am

1 stop18h 52m

Rome Fiumicino

Sat 10/4

10:00 am-7:47 pm

2 stops16h 47m

$1,042

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Tue 9/9

12:01 pm-11:25 am

2 stops16h 24m

Venice Marco Polo

Fri 9/26

6:25 am-5:36 pm

3 stops18h 11m

$4,211

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Showing 1-10 of 12 results
1
2

Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City, Florida to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Italy (average of $703). Flying from Panama City, Florida to Italy in June is currently the most expensive (average of $1,211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Italy as you normally would.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated July 2, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
KLM
7.8
Good
1,366 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Scandinavian Airlines
7.3
Good
1,415 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Italy.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Italy (average of $703). Flying from Panama City, Florida to Italy in June is currently the most expensive (average of $1,211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Italy

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Madrid flights
Miami to Leonardo da Vinci/Fiumicino flights
Miami to Barcelona-El Prat flights
Miami to Charles de Gaulle flights
Orlando to Heathrow flights
Miami to Heathrow flights
Miami to Istanbul flights
Orlando to Gatwick flights
Orlando to Charles de Gaulle flights
Tampa to Heathrow flights
Tampa to Frankfurt flights
Miami to Gatwick flights
Miami to London City flights
Orlando to London City flights
Miami to Lisbon flights
Miami to Orly flights
Orlando to Frankfurt flights
Fort Lauderdale to Madrid flights
Miami to Athens flights
Miami to Frankfurt flights
Orlando to Dublin flights
Miami to Stansted flights
Orlando to Leonardo da Vinci/Fiumicino flights
Orlando to Orly flights
Orlando to Madrid flights
Tampa to Gatwick flights
Miami to Zurich flights
Miami to Malpensa flights
Miami to Linate flights
Miami to Luton flights
Miami to Beauvais-Tille flights
Tampa to Amsterdam flights
Miami to Sabiha Gokcen flights
Orlando to Keflavik Intl flights
Fort Lauderdale to Charles de Gaulle flights
Miami to Munich flights
Miami to Keflavik Intl flights
Fort Lauderdale to Barcelona-El Prat flights
Tampa to Madrid flights
Tampa to Leonardo da Vinci/Fiumicino flights
Miami to Amsterdam flights
West Palm Beach to Barcelona-El Prat flights
Tampa to Athens flights
Orlando to Athens flights
Tampa to Charles de Gaulle flights
Orlando to Lisbon flights
Orlando to Barcelona-El Prat flights
Miami to Frederic Chopin flights
Tampa to London City flights
Jacksonville to Charles de Gaulle flights

Top 2 airlines flying from Panama City to Italy

Discover the top 2 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$724Average$1,161FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$743Average$1,150FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.