HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$557+ Cheap flights from Key West (EYW) to Italy

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — NAP
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Key West to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Key West to Italy

Keep the following information in mind while searching for Key West to Italy flight deals. Data was last updated October 14, 2025.

Round-trip from

$557
(American Airlines)
From Key West to Italy
Search Deals

Find flight deals from Key West to Italy

Cheapest flights from Key West to Italy
Explore the most affordable flight options available from Key West to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:05 pmEYW - FCO
2 stops17h 05mAmerican Airlines
Mon 12/151:10 pmFCO - EYW
1 stop32h 57mAmerican Airlines
Deal found 10/12$557
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:40 amEYW - FCO
2 stops18h 15mDelta
Mon 12/156:10 amFCO - EYW
2 stops19h 56mDelta
Deal found 10/14$560
This Air France deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:10 pmEYW - FCO
1 stop34h 20mAir France
Mon 12/1510:05 amFCO - EYW
1 stop16h 01mAir France
Deal found 10/12$561
This Air France deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:10 pmEYW - FCO
1 stop34h 20mAir France
Sun 12/1412:40 pmFCO - EYW
1 stop34h 35mAir France
Deal found 10/12$566
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:53 pmEYW - FCO
1 stop33h 52mUnited Airlines
Sun 12/149:45 amFCO - EYW
1 stop35h 24mUnited Airlines
Deal found 10/14$642
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:00 pmEYW - FCO
2 stops25h 00mUnited Airlines
Sat 11/1512:20 pmFCO - EYW
3 stops31h 26mUnited Airlines
Deal found 10/14$710
This KLM deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:40 amEYW - PSA
2 stops19h 40mKLM
Mon 11/107:40 pmPSA - EYW
2 stops30h 13mKLM
Deal found 10/13$724
This Air France deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:40 amEYW - FCO
1 stop20h 50mMultiple Airlines
Sat 11/1512:40 pmFCO - EYW
1 stop37h 13mMultiple Airlines
Deal found 10/14$737
This Expedia deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:53 pmEYW - FCO
2 stops41h 52mBritish Airways
Sat 11/158:30 pmFCO - EYW
2 stops28h 53mBritish Airways
Deal found 10/14$781
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:46 pmEYW - FCO
1 stop14h 14mAmerican Airlines
Sat 11/151:10 pmFCO - EYW
2 stops28h 49mAmerican Airlines
Deal found 10/14$825
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:05 pmEYW - FCO
2 stops19h 10mUnited Airlines
Fri 1/21:10 pmFCO - EYW
3 stops56h 04mUnited Airlines
Deal found 10/13$1,569
This Priceline deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/291:46 pmEYW - FCO
2 stops17h 04mBritish Airways
Sat 1/37:00 pmFCO - EYW
2 stops30h 39mBritish Airways
Deal found 10/12$1,833

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Key West to Italy that are best for you.

Fly from

Key West

Fly to

Italy

Route

Depart

Return

Price

Key WestRome

EYW - FCO

EYWFCO

Key West

Thu 12/11

8:05 pm-7:10 pm

2 stops17h 05m

Rome Fiumicino

Mon 12/15

1:10 pm-4:07 pm

1 stop32h 57m

$557

Key WestRome

EYW - FCO

EYWFCO

Key West

Thu 12/11

7:40 am-7:55 am

2 stops18h 15m

Rome Fiumicino

Mon 12/15

6:10 am-5:15 pm

2 stops17h 05m

$560

Key WestRome

EYW - FCO

EYWFCO

Key West

Thu 12/11

7:40 am-9:45 am

2 stops20h 05m

Rome Fiumicino

Sun 12/14

6:10 am-8:06 pm

2 stops19h 56m

$560

Key WestRome

EYW - FCO

EYWFCO

Key West

Thu 12/11

6:10 pm-10:30 am

1 stop34h 20m

Rome Fiumicino

Mon 12/15

10:05 am-8:06 pm

1 stop16h 01m

$561

Key WestPisa

EYW - PSA

EYWPSA

Key West

Thu 11/6

7:40 am-9:20 am

2 stops19h 40m

Pisa Gal Galilei

Mon 11/10

7:40 pm-7:53 pm

2 stops30h 13m

$724

Key WestFlorence

EYW - FLR

EYWFLR

Key West

Thu 3/26

6:30 pm-4:30 pm

2 stops17h 00m

Florence Peretola

Mon 3/30

1:45 pm-3:06 pm

2 stops55h 21m

$914

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Best time to book a flight from Key West to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Italy

What is the cheapest time of day to fly from EYW to IT?

Find hourly flight availability from Key West to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

It’s optimal to fly from Key West to Italy at noon. By choosing this option you can save up to 26% on the cost of your flight, compared to a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from Key West to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Key West to Italy?

    If you book a flight to Italy from Key West, you will be flying from Key West, which is the city’s only airport. Key West (EYW) is located 2.6 mi from the center of Key West.

  • How long is the flight from Key West to Italy?

    There are many flights that can get you from Key West to Italy in 17h 05m. Fly via American Airlines, Delta, or KLM to get the fastest option. Key West and Italy are separated by a distance of 5298 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Key West to Italy?

    The most popular flight routes from Key West to Italy are Key West - Rome Fiumicino, Key West - Pisa Gal Galilei and Key West - Florence Peretola.

  • Can I find deals for flights from Key West to Italy that include hotel bookings?

    Yes. In addition to deals on Key West to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Italy.

  • Can I find deals for business class flights from Key West to Italy?

    Yes. Cheapflights offers flight deals from Key West to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key West to Italy

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Madrid flights
Miami to Heathrow flights
Miami to Charles de Gaulle flights
Orlando to Heathrow flights
Miami to Leonardo da Vinci/Fiumicino flights
Miami to Barcelona-El Prat flights
Tampa to Heathrow flights
Miami to Istanbul flights
Fort Lauderdale to Madrid flights
Orlando to Gatwick flights
Orlando to Charles de Gaulle flights
Miami to Lisbon flights
Miami to Gatwick flights
Miami to Orly flights
Orlando to Madrid flights
Miami to Frankfurt flights
Miami to London City flights
Miami to Zurich flights
Orlando to Frankfurt flights
Miami to Malpensa flights
Orlando to London City flights
Tampa to Frankfurt flights
Fort Lauderdale to Charles de Gaulle flights
Miami to Linate flights
Orlando to Dublin flights
Orlando to Orly flights
Fort Lauderdale to Leonardo da Vinci/Fiumicino flights
Miami to Amsterdam flights
Miami to Stansted flights
Orlando to Leonardo da Vinci/Fiumicino flights
Tampa to Gatwick flights
Fort Lauderdale to Heathrow flights
Miami to Vicenza flights
Miami to Luton flights
Orlando to Amsterdam flights
Orlando to Barcelona-El Prat flights
Tampa to London City flights
Miami to Munich flights
Miami to Sabiha Gokcen flights
Orlando to Istanbul flights
Miami to Beauvais-Tille flights
Tampa to Leonardo da Vinci/Fiumicino flights
Miami to Athens flights
Miami to Frederic Chopin flights
Orlando to Keflavik Intl flights
Tampa to Amsterdam flights
Orlando to Lisbon flights
Fort Lauderdale to Barcelona-El Prat flights
Tampa to Madrid flights
Orlando to Stansted flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.