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$634+ Cheap flights from Knoxville (TYS) to Istanbul

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IST
May 17 — May 241
Sat 5/17
Sat 5/24
1 adult, Economy
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Cheap flight deals from Knoxville to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Istanbul (TR5). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2025.

Round-trip from

$690
(United Airlines)

Popular in

October

Cheapest in

August

Average price

$1,180
From Knoxville McGhee Tyson to Istanbul
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($169 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($114 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
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Find flight deals from Knoxville to Istanbul

Cheapest flights from Knoxville to Istanbul
Explore the most affordable flight options available from Knoxville to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2025.

This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:10 pmTYS - IST
2 stops26h 00mDelta
Fri 11/215:10 amIST - TYS
2 stops21h 03mDelta
Deal found 5/12$634
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/710:35 amTYS - IST
2 stops28h 10mUnited Airlines
Tue 12/166:30 amIST - TYS
2 stops20h 12mUnited Airlines
Deal found 5/11$635
This Lufthansa deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:00 pmTYS - IST
2 stops24h 45mLufthansa
Mon 12/227:00 pmIST - TYS
2 stops33h 58mLufthansa
Deal found 5/11$654
This Gurufare deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:45 amTYS - IST
2 stops21h 40mBritish Airways
Fri 12/198:10 amIST - TYS
2 stops41h 31mBritish Airways
Deal found 5/12$668
This Orbitz deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/36:26 pmTYS - SAW
2 stops37h 54mBritish Airways
Wed 7/304:15 pmSAW - TYS
2 stops35h 40mBritish Airways
Deal found 5/12$1,096
This Mytrip deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/39:45 amTYS - SAW
3 stops31h 00mMultiple Airlines
Tue 7/291:00 amSAW - TYS
3 stops45h 09mMultiple Airlines
Deal found 5/12$1,301
This Air Canada deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:55 pmTYS - IST
3 stops19h 10mAir Canada
Tue 12/166:30 amIST - TYS
3 stops20h 12mAir Canada
Deal found 5/11$1,337
This Mytrip deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/39:45 amTYS - IST
3 stops35h 05mMultiple Airlines
Wed 7/302:00 pmIST - TYS
2 stops32h 09mMultiple Airlines
Deal found 5/12$1,387
This oojo deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:33 pmTYS - SAW
2 stops35h 37mQatar Airways
Fri 11/218:10 pmSAW - TYS
2 stops36h 09mQatar Airways
Deal found 5/12$1,615
This oojo deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:00 pmTYS - IST
2 stops43h 35mEmirates
Mon 12/151:50 amIST - TYS
2 stops27h 08mEmirates
Deal found 5/11$2,269
This Gotogate deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/35:45 amTYS - IST
3 stops40h 00mEthiopian Air
Tue 7/2912:10 amIST - TYS
3 stops45h 48mEthiopian Air
Deal found 5/12$2,677
This oojo deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/17:35 amTYS - IST
2 stops22h 10mRoyal Jordanian
Fri 10/318:55 pmIST - TYS
2 stops31h 39mRoyal Jordanian
Deal found 5/11$4,143

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2025.
Use the filters below to find and compare flights from Knoxville to Istanbul that are best for you.

Fly from

Knoxville

Fly to

Istanbul

Route

Depart

Return

Price

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 11/8

7:10 pm-10:45 pm

2 stops43h 35m

Istanbul

Sat 11/22

6:30 am-9:59 am

2 stops35h 29m

$690

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 11/8

5:39 pm-10:45 pm

2 stops45h 06m

Istanbul

Sat 11/22

7:00 pm-11:42 pm

2 stops36h 42m

$709

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Thu 7/3

6:26 pm-3:20 pm

2 stops37h 54m

Istanbul Sabiha Gokcen

Wed 7/30

4:15 pm-8:55 pm

2 stops35h 40m

$1,096

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 7/3

6:26 pm-12:20 am

2 stops46h 54m

Istanbul

Wed 7/30

5:35 pm-5:35 pm

2 stops31h 00m

$1,124

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Thu 7/3

9:45 am-11:45 pm

3 stops31h 00m

Istanbul Sabiha Gokcen

Tue 7/29

1:00 am-3:09 pm

3 stops45h 09m

$1,301

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 7/3

9:45 am-3:50 am

3 stops35h 05m

Istanbul

Wed 7/30

2:00 pm-3:09 pm

2 stops32h 09m

$1,387

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 11/8

2:55 pm-6:10 pm

3 stops19h 15m

Istanbul

Sat 11/22

6:30 am-6:42 pm

3 stops20h 12m

$1,404

KnoxvilleIstanbul

TYS - SAW

TYSSAW

Knoxville McGhee Tyson

Thu 5/15

7:10 am-12:10 pm

2 stops46h 00m

Istanbul Sabiha Gokcen

Sat 5/17

8:05 pm-8:55 pm

2 stops31h 50m

$2,326

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 7/3

5:45 am-4:45 am

3 stops40h 00m

Istanbul

Tue 7/29

12:10 am-2:58 pm

3 stops45h 48m

$2,677

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 7/3

7:00 am-9:35 pm

2 stops55h 35m

Istanbul

Tue 7/29

2:10 am-10:35 pm

2 stops27h 25m

$2,794

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/11

Showing 1-10 of 11 results
1
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Best time to book a flight from Knoxville to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Istanbul

What is the cheapest time of day to fly from TYS to IST?

Find hourly flight availability from Knoxville to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 12, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 16% on flights from Knoxville to Istanbul by exploring options for tickets at noon.

Rainfall in Istanbul by month

Plan your trip to Istanbul by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Istanbul ranges from 0.4 - 3.9 inches per month. December is typically the wettest month, when rainfall can reach 3.9 in. July is typically the driest time to visit Istanbul when rainfall is around 0.4 in.

Temperature in Istanbul by month

Plan your trip to Istanbul by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Istanbul, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated May 12, 2025.
Emirates
8.0
Very good
3,228 reviews

Boarding

8.1

Entertainment

8.2

Crew

8.3

Food

7.8

Overall

8.0

Comfort

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Emirates
8.0
Very good
3,228 reviews
Emirates
8.0
Very good
3,228 reviews

Boarding

8.1

Entertainment

8.2

Crew

8.3

Food

7.8

Overall

8.0

Comfort

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Qatar Airways
7.4
Good
3,570 reviews
Emirates
8.0
Very good
3,228 reviews

Boarding

8.1

Entertainment

8.2

Crew

8.3

Food

7.8

Overall

8.0

Comfort

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
United Airlines
7.4
Good
8,724 reviews
Emirates
8.0
Very good
3,228 reviews

Boarding

8.1

Entertainment

8.2

Crew

8.3

Food

7.8

Overall

8.0

Comfort

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Ethiopian Air
7.2
Good
774 reviews
Emirates
8.0
Very good
3,228 reviews

Boarding

8.1

Entertainment

8.2

Crew

8.3

Food

7.8

Overall

8.0

Comfort

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.
Air Canada
7.0
Good
9,328 reviews
Emirates
8.0
Very good
3,228 reviews

Boarding

8.1

Entertainment

8.2

Crew

8.3

Food

7.8

Overall

8.0

Comfort

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2024

IAD - DXB

Not so good. Flight was departed 2 hours late from DC and we missed our connecting flight from Dubai to Mumbai. Our flight Dubai to Mumbai got delayed by three hours. Once we arrived Bombay airport we didnot get all our luggage bags. We were missing two luggage bags so found out that our those two luggage bags are coming in different flight. First they gave us wrong flight information in which our missing luggage coming and wrong phone number to whom we should reach out. I spent hours and hours at the airport to find out our luggage bags. After four five hours later and hectic time at the airport to get our luggage bags. Overall poor communication with emirates staff at the airport and no one is helpful.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Istanbul?

    If you book a flight to Istanbul from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Istanbul per day from 6 different airlines.

  • What are the cheapest airlines flying from Knoxville to Istanbul round-trip?

    Our cheapest airline available from Knoxville to Istanbul is United Airlines. Our recent data shows that you can find tickets from as low as $690 on this airline. Additional options worth looking into are Lufthansa and British Airways, starting at $709 and $1,096 round-trip. These flights start at 45% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Istanbul that include hotel bookings?

    Yes. In addition to deals on Knoxville to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Istanbul.

  • Can I find deals for business class flights from Knoxville to Istanbul?

    Yes. Cheapflights offers flight deals from Knoxville to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Istanbul?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Istanbul (average of $923). Flying from Knoxville to Istanbul in June is currently the most expensive (average of $1,419). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Knoxville to Istanbul

Discover the top 6 airlines that operate flights from Knoxville to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$770Average$1,173FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$781Average$1,121FlexibilityNo cancel feeOn-time76%
DeltaCheapest$797Average$1,089FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$820Average$1,218FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$987Average$1,160FlexibilityNo cancel feeOn-time69%
Air FranceCheapest$2,396Average$2,396FlexibilityNo cancel feeOn-time77%

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