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$142+ Cheap flights from Santo Domingo (SDQ) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — IND
Mar 10 — Mar 171
Tue 3/10
Tue 3/17
1 adult, Economy
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Cheap flight deals from Santo Domingo to Indiana

Cheapest flights from Santo Domingo to Indiana
Explore the most affordable flight options available from Santo Domingo to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.

This eDestinos deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/193:32 pm
SDQ
-
ORD
1 stop7h 41m
Spirit Airlines
Mon 2/238:16 pm
ORD
-
SDQ
1 stop16h 04m
Spirit Airlines
Deal found 2/7$242
This Cheapflightsfares deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/162:52 am
SDQ
-
ORD
1 stop9h 25m
Spirit Airlines
Tue 3/245:05 am
ORD
-
SDQ
1 stop7h 10m
Spirit Airlines
Deal found 2/5$276
This Cheapflightsfares deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:32 pm
SDQ
-
ORD
1 stop7h 41m
Spirit Airlines
Mon 3/28:16 pm
ORD
-
SDQ
1 stop16h 04m
Spirit Airlines
Deal found 2/5$278
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:52 am
SDQ
-
ORD
1 stop9h 25m
Spirit Airlines
Tue 4/287:05 am
ORD
-
SDQ
1 stop6h 27m
Spirit Airlines
Deal found 2/5$282
This Cheapflightsfares deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/183:32 pm
SDQ
-
ORD
1 stop10h 15m
Spirit Airlines
Sat 2/288:16 pm
ORD
-
SDQ
1 stop16h 04m
Spirit Airlines
Deal found 2/5$284
This Cheapflightsfares deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:32 pm
SDQ
-
ORD
1 stop7h 41m
Spirit Airlines
Wed 3/45:15 am
ORD
-
SDQ
1 stop7h 05m
Spirit Airlines
Deal found 2/7$290
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:32 pm
SDQ
-
ORD
1 stop9h 52m
Multiple Airlines
Sun 3/13:40 pm
ORD
-
SDQ
1 stop20h 40m
Multiple Airlines
Deal found 2/6$291
This Cheapflightsfares deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:20 pm
SDQ
-
ORD
1 stop9h 57m
Spirit Airlines
Wed 3/256:10 pm
ORD
-
SDQ
1 stop6h 28m
Spirit Airlines
Deal found 2/5$300
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/203:32 pm
SDQ
-
IND
1 stop8h 16m
Multiple Airlines
Mon 3/27:31 pm
IND
-
SDQ
2 stops43h 58m
Multiple Airlines
Deal found 2/7$309
This Priceline deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/222:52 am
SDQ
-
ORD
1 stop15h 23m
Spirit Airlines
Mon 3/306:10 pm
ORD
-
SDQ
1 stop6h 28m
Spirit Airlines
Deal found 2/5$311
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/171:11 pm
SDQ
-
ORD
1 stop30h 35m
Multiple Airlines
Tue 3/107:25 pm
ORD
-
SDQ
1 stop20h 04m
Multiple Airlines
Deal found 2/5$312
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:37 pm
SDQ
-
IND
2 stops19h 40m
Multiple Airlines
Mon 4/276:40 pm
IND
-
SDQ
1 stop19h 52m
Multiple Airlines
Deal found 2/7$348

Find flight deals from Santo Domingo to Indiana

Keep the following information in mind while searching for Santo Domingo to Indiana flight deals. Data was last updated February 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$276
(Cheapflightsfares)

One-way from

$142
(eDestinos)

Popular in

January

Cheapest in

September

Average price

$585
Provider with most accurate pricing for Santo Domingo Las Americas-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Indianapolis flights.
Search Deals
From Santo Domingo Las Americas to Indiana
Search Deals
One-way flight from Santo Domingo Las Americas to Indiana
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Santo Domingo to Indiana that are best for you.

Fly from

Santo Domingo

Fly to

Indiana

Route

Depart

Return

Price

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 2/19

3:32 pm-9:13 pm

1 stop7h 41m

Chicago O'Hare Intl

Mon 2/23

8:16 pm-2:20 pm

1 stop16h 04m

$242

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 2/26

3:32 pm-9:13 pm

1 stop7h 41m

Chicago O'Hare Intl

Mon 3/2

8:16 pm-2:20 pm

1 stop16h 04m

$278

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 4/8

2:52 am-11:17 am

1 stop9h 25m

Chicago O'Hare Intl

Tue 4/28

7:05 am-2:32 pm

1 stop6h 27m

$282

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 2/18

3:32 pm-11:47 pm

1 stop10h 15m

Chicago O'Hare Intl

Sat 2/28

8:16 pm-2:20 pm

1 stop16h 04m

$284

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 4/8

10:19 am-9:50 am

1 stop24h 31m

Chicago O'Hare Intl

Tue 4/28

6:34 pm-4:29 pm

1 stop20h 55m

$290

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Tue 3/10

2:32 pm-9:13 pm

1 stop7h 41m

Chicago O'Hare Intl

Sun 3/15

9:15 am-1:38 am

1 stop15h 23m

$302

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 2/20

3:32 pm-10:48 pm

1 stop8h 16m

Indianapolis

Mon 3/2

7:31 pm-4:29 pm

2 stops43h 58m

$309

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 4/16

3:37 pm-11:41 pm

1 stop9h 04m

Chicago O'Hare Intl

Tue 4/21

7:05 am-2:32 pm

1 stop6h 27m

$311

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 4/8

10:19 am-9:50 am

1 stop24h 31m

Chicago O'Hare Intl

Mon 4/27

5:15 am-2:32 pm

1 stop8h 17m

$317

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 5/7

3:37 pm-11:41 pm

1 stop9h 04m

Chicago O'Hare Intl

Sun 5/17

7:05 am-2:32 pm

1 stop6h 27m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/7

Showing 1-10 of 60 results
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Best time to book a flight from Santo Domingo to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Indiana

What is the cheapest month to book a flight from Santo Domingo to Indiana?

Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Indiana (average of $328). Flying from Santo Domingo to Indiana in November is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 8, 2026.
Read through reviews of airlines operating flights from Santo Domingo to Indiana, such as Delta and Spirit Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,173 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,173 reviews
Delta
7.9
Good
8,173 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,430 reviews
Delta
7.9
Good
8,173 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Indiana?

    For a flight from Santo Domingo to Indiana, you will be flying from Las Americas. Santo Domingo Las Americas (SDQ) is just 17.5 mi from the center of the city.

  • How long is the flight from Santo Domingo to Indiana?

    Spirit Airlines and United Airlines can get you from Santo Domingo to Indiana in just under 7h 41m. Your travel time can differ by up to 4h 31m. There are 1947 mi between Santo Domingo and Indiana. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Santo Domingo to Indiana one-way?

    The cheapest airlines for a one-way flight from Santo Domingo to Indiana are Spirit Airlines ($162), Delta ($342), and American Airlines ($346).

  • What are the most popular routes from Santo Domingo to Indiana?

    The most popular flight routes from Santo Domingo to Indiana are Santo Domingo Las Americas - Chicago O'Hare Intl, Santo Domingo Las Americas - Chicago Midway and Santo Domingo Las Americas - Cincinnati Cinci./N. Kentucky.

  • Can I find deals for flights from Santo Domingo to Indiana that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Indiana.

  • Can I find deals for business class flights from Santo Domingo to Indiana?

    Yes. Cheapflights offers flight deals from Santo Domingo to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Indiana?

    Currently, September is the cheapest month in which you can book a flight from Santo Domingo to Indiana (average of $328). Flying from Santo Domingo to Indiana in November is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
Santo Domingo to John F Kennedy Intl flights
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Santiago de los Caballeros to John F Kennedy Intl flights
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Santiago de los Caballeros to Orlando flights
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Punta Cana to John F Kennedy Intl flights
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Punta Cana to O'Hare Intl flights
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Santiago de los Caballeros to Fort Lauderdale flights
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Punta Cana to Dulles Intl flights
Santo Domingo to Tampa flights
Santiago de los Caballeros to Boston flights
Punta Cana to Miami flights
Punta Cana to Baltimore flights
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Punta Cana to LaGuardia flights
Punta Cana to Boston flights
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Santo Domingo to Dallas/Fort Worth flights
Punta Cana to Tampa flights
Santo Domingo to O'Hare Intl flights
Puerto Plata to John F Kennedy Intl flights
Punta Cana to Orlando flights
Santo Domingo to Reagan-National flights
Santo Domingo to Dulles Intl flights
Santo Domingo to George Bush Intcntl flights
Punta Cana to Hobby flights
Santo Domingo to West Palm Beach flights
Santo Domingo to Charlotte flights
Punta Cana to Fort Lauderdale flights
Punta Cana to George Bush Intcntl flights
Santo Domingo to Denver flights
Santo Domingo to Columbus flights
Punta Cana to Philadelphia flights
Santo Domingo to Los Angeles flights
Punta Cana to Los Angeles flights
Santo Domingo to Raleigh flights
Santo Domingo to Salt Lake City flights
Santo Domingo to Baltimore flights
Punta Cana to Midway flights

Top 2 airlines flying from Santo Domingo to Indiana

Discover the top 2 airlines that operate flights from Santo Domingo to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$326Average$429FlexibilityNo cancel feeOn-time65%
DeltaCheapest$559Average$657FlexibilityNo cancel feeOn-timeN/A

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