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$204+ Cheap flights from Santo Domingo (SDQ) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — GYE
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo are usually found in October or February, booked 47 days in advance, depart on a Wednesday or Monday and return on a Monday

Find flight deals from Santo Domingo to Guayaquil

Cheapest flights from Santo Domingo to Guayaquil
Explore the most affordable flight options available from Santo Domingo to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This Avianca deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2012:20 pmSDQ - GYE
1 stop12h 15mAvianca
dom. 11/234:40 amGYE - SDQ
1 stop11h 10mAvianca
Deal found 11/4$436
This Copa Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/58:55 amSDQ - GYE
1 stop5h 39mCopa Airlines
lun. 12/152:35 pmGYE - SDQ
1 stop7h 21mCopa Airlines
Deal found 11/5$440
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/1111:55 amSDQ - GYE
1 stop12h 46mCopa Airlines
vie. 11/146:02 amGYE - SDQ
1 stop9h 13mCopa Airlines
Deal found 11/3$452
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/222:15 pmSDQ - GYE
1 stop7h 28mCopa Airlines
jue. 12/44:32 amGYE - SDQ
1 stop10h 43mCopa Airlines
Deal found 11/4$486
This Avianca deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/15:45 pmSDQ - GYE
1 stop8h 20mAvianca
mié. 12/36:55 pmGYE - SDQ
1 stop15h 30mAvianca
Deal found 11/3$494
This Copa Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/118:55 amSDQ - GYE
1 stop5h 39mCopa Airlines
dom. 1/114:33 amGYE - SDQ
1 stop12h 32mCopa Airlines
Deal found 11/6$512
This Avianca deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/45:45 pmSDQ - GYE
2 stops16h 15mAvianca
lun. 12/86:30 amGYE - SDQ
2 stops9h 20mAvianca
Deal found 11/6$517

Cheap flight deals from Santo Domingo to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$436
(Avianca)

One-way from

$204
(Priceline)

Popular in

August

Cheapest in

October

Average price

$428
Provider with most accurate pricing for Santo Domingo Las Americas-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Santo Domingo to Guayaquil that are best for you.

Fly from

Santo Domingo

Fly to

Guayaquil

Route

Depart

Return

Price

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

jue. 4/23

11:45 am-10:40 pm

1 stop11h 55m

Guayaquil Jose Joaquin de Olmedo

sáb. 4/25

3:35 am-5:15 pm

1 stop12h 40m

$436

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

mié. 3/18

5:45 pm-1:05 am

1 stop8h 20m

Guayaquil Jose Joaquin de Olmedo

lun. 3/30

3:35 am-10:50 am

1 stop6h 15m

$436

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

jue. 12/4

12:20 pm-5:45 pm

1 stop6h 25m

Guayaquil Jose Joaquin de Olmedo

dom. 12/7

4:40 am-4:50 pm

1 stop11h 10m

$436

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

jue. 1/15

6:00 am-8:46 pm

1 stop15h 46m

Guayaquil Jose Joaquin de Olmedo

lun. 1/19

4:33 am-11:32 am

1 stop5h 59m

$440

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

jue. 12/4

6:00 am-11:18 am

1 stop6h 18m

Guayaquil Jose Joaquin de Olmedo

lun. 12/8

12:20 pm-2:26 am

1 stop13h 06m

$440

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

vie. 12/5

8:55 am-1:34 pm

1 stop5h 39m

Guayaquil Jose Joaquin de Olmedo

lun. 12/15

12:20 pm-10:56 pm

1 stop9h 36m

$440

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

jue. 1/15

6:00 am-8:46 pm

1 stop15h 46m

Guayaquil Jose Joaquin de Olmedo

jue. 1/22

6:33 pm-11:32 am

1 stop15h 59m

$440

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

jue. 11/20

12:20 pm-5:45 pm

1 stop6h 25m

$204

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

lun. 2/9

8:50 am-1:34 pm

1 stop5h 44m

$239

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

lun. 12/22

8:55 am-8:43 pm

1 stop12h 48m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 16 results
1
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Compare providers for flights from Santo Domingo to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Guayaquil in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Guayaquil flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Guayaquil flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Guayaquil flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Guayaquil

How far ahead should I book a flight from Santo Domingo to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Guayaquil. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Guayaquil, you should look to book at least 46 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

Currently, November is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $202). Flying from Santo Domingo to Guayaquil in July is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to GYE?

Find hourly flight availability from Santo Domingo to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

When flying from Santo Domingo to Guayaquil, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 50% versus a flight at noon.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated noviembre 6, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from Santo Domingo to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,563 reviews

Overall

7.6

Food

6.9

Crew

8.1

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,563 reviews
Copa Airlines
7.6
Good
1,563 reviews

Overall

7.6

Food

6.9

Crew

8.1

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,469 reviews
Copa Airlines
7.6
Good
1,563 reviews

Overall

7.6

Food

6.9

Crew

8.1

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Guayaquil?

    For as low as $436, Avianca can have you in Guayaquil from Santo Domingo in 11h 55m. The distance between Santo Domingo and Guayaquil is about 1582 mi.

  • What are the cheapest airlines flying from Santo Domingo to Guayaquil round-trip?

    According to our current data, Avianca ($372), and Copa Airlines ($413) offers the cheapest pricing from Santo Domingo to Guayaquil. These flights start at 12% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santo Domingo to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Guayaquil.

  • Can I find deals for business class flights from Santo Domingo to Guayaquil?

    Yes. Cheapflights offers flight deals from Santo Domingo to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

    Currently, November is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $202). Flying from Santo Domingo to Guayaquil in July is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Santo Domingo to Quito flights

Top 2 airlines flying from Santo Domingo to Guayaquil

Discover the top 2 airlines that operate flights from Santo Domingo to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$372Average$420FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$413Average$437FlexibilityNo cancel feeOn-time70%

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