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Guayaquil

$204+ Cheap flights from Santo Domingo (SDQ) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — GYE
Aug 24 — Aug 311
Sun 8/24
Sun 8/31
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo are usually found in October or September, booked 27 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Santo Domingo to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 19, 2025.

Round-trip from

$413
(Arajet)

One-way from

$204
(Avianca)

Popular in

March

Cheapest in

October

Average price

$438
From Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
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Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Santo Domingo to Guayaquil

Cheapest flights from Santo Domingo to Guayaquil
Explore the most affordable flight options available from Santo Domingo to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2025.

This Arajet deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/71:55 pmSDQ - GYE
1 stop13h 02mMultiple Airlines
Mon 9/154:17 amGYE - SDQ
1 stop10h 53mMultiple Airlines
Deal found 8/17$413
This Avianca deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/611:45 amSDQ - GYE
1 stop11h 55mAvianca
Tue 9/93:35 amGYE - SDQ
1 stop12h 40mAvianca
Deal found 8/17$434
This Copa Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/75:25 amSDQ - GYE
1 stop6h 50mCopa Airlines
Sun 9/76:32 pmGYE - SDQ
1 stop15h 26mCopa Airlines
Deal found 8/18$470
This Priceline deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/811:45 amSDQ - GYE
1 stop12h 35mAvianca
Tue 9/166:10 amGYE - SDQ
2 stops10h 05mAvianca
Deal found 8/17$482
This Copa Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/188:57 amSDQ - GYE
1 stop5h 49mCopa Airlines
Wed 9/106:32 pmGYE - SDQ
1 stop15h 26mCopa Airlines
Deal found 8/17$595
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:10 amSDQ - GYE
2 stops15h 43mMultiple Airlines
Thu 10/99:45 amGYE - SDQ
1 stop6h 30mMultiple Airlines
Deal found 8/18$610
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/182:10 amSDQ - GYE
1 stop7h 25mMultiple Airlines
Sat 10/254:15 amGYE - SDQ
1 stop5h 35mMultiple Airlines
Deal found 8/19$615
This Copa Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1811:54 amSDQ - GYE
1 stop13h 01mCopa Airlines
Fri 9/54:27 amGYE - SDQ
1 stop5h 31mCopa Airlines
Deal found 8/17$639

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2025.
Use the filters below to find and compare flights from Santo Domingo to Guayaquil that are best for you.

Fly from

Santo Domingo

Fly to

Guayaquil

Route

Depart

Return

Price

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sun 9/7

1:55 pm-1:57 am

1 stop13h 02m

Guayaquil Jose Joaquin de Olmedo

Mon 9/15

4:17 am-4:10 pm

1 stop10h 53m

$413

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sat 9/6

11:45 am-10:40 pm

1 stop11h 55m

Guayaquil Jose Joaquin de Olmedo

Tue 9/9

3:35 am-5:15 pm

1 stop12h 40m

$434

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Thu 10/2

11:45 am-11:20 pm

1 stop12h 35m

Guayaquil Jose Joaquin de Olmedo

Wed 10/8

3:35 am-10:50 am

1 stop6h 15m

$434

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sun 9/7

6:10 pm-9:55 am

1 stop16h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 9/14

3:35 am-10:50 am

1 stop6h 15m

$434

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sun 10/19

6:10 pm-8:35 am

1 stop15h 25m

Guayaquil Jose Joaquin de Olmedo

Fri 10/24

3:35 am-10:50 am

1 stop6h 15m

$434

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sun 11/30

5:45 pm-11:35 pm

1 stop6h 50m

$204

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Tue 8/26

6:10 pm-9:55 am

1 stop16h 45m

$212

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Tue 8/26

11:54 am-11:55 pm

1 stop13h 01m

$235

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Mon 8/25

11:54 am-11:15 am

1 stop24h 21m

$235

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Sun 8/24

8:55 am-11:20 pm

3 stops39h 25m

$340

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 15 results
1
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Best time to book a flight from Santo Domingo to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Guayaquil

How far ahead should I book a flight from Santo Domingo to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Guayaquil. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Guayaquil, you should look to book at least 27 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $440). Flying from Santo Domingo to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to GYE?

Find hourly flight availability from Santo Domingo to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 19, 2025.

When flying from Santo Domingo to Guayaquil, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 30% versus a flight in the morning.

How much does it cost to fly round-trip from Santo Domingo to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 19, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from Santo Domingo to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,510 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,510 reviews
Copa Airlines
7.5
Good
1,510 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,409 reviews
Copa Airlines
7.5
Good
1,510 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Guayaquil?

    For as low as $434, Avianca can have you in Guayaquil from Santo Domingo in 11h 55m. The distance between Santo Domingo and Guayaquil is about 1582 mi.

  • What are the cheapest airlines flying from Santo Domingo to Guayaquil round-trip?

    According to our current data, Avianca ($372), and Copa Airlines ($404) offers the cheapest pricing from Santo Domingo to Guayaquil. These flights start at 11% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santo Domingo to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Guayaquil.

  • Can I find deals for business class flights from Santo Domingo to Guayaquil?

    Yes. Cheapflights offers flight deals from Santo Domingo to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $440). Flying from Santo Domingo to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santo Domingo to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Santo Domingo to Quito flights

Top 2 airlines flying from Santo Domingo to Guayaquil

Discover the top 2 airlines that operate flights from Santo Domingo to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$372Average$420FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$404Average$430FlexibilityNo cancel feeOn-time70%

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