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$150+ Cheap flights from Santo Domingo (SDQ) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — GYE
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo are usually found in August or September, booked 45 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Santo Domingo to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$400
(Gotogate)

One-way from

$150
(Arajet)

Popular in

March

Cheapest in

August

Average price

$418
From Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Santo Domingo Las Americas to Guayaquil Jose Joaquin de Olmedo
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Santo Domingo to Guayaquil

Cheapest flights from Santo Domingo to Guayaquil
Explore the most affordable flight options available from Santo Domingo to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Gotogate deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:10 pmSDQ - GYE
1 stop5h 30mMultiple Airlines
Thu 7/3112:04 amGYE - SDQ
1 stop14h 24mMultiple Airlines
Deal found 6/9$400
This Copa Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/42:07 pmSDQ - GYE
1 stop7h 23mCopa Airlines
Tue 7/86:31 pmGYE - SDQ
1 stop15h 28mCopa Airlines
Deal found 6/11$407
This Avianca deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:10 pmSDQ - GYE
1 stop6h 10mAvianca
Tue 8/124:15 amGYE - SDQ
1 stop5h 35mAvianca
Deal found 6/12$424
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/202:46 pmSDQ - GYE
2 stops24h 29mDelta
Sun 6/298:40 pmGYE - SDQ
2 stops39h 41mDelta
Deal found 6/11$7,472

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Santo Domingo to Guayaquil that are best for you.

Fly from

Santo Domingo

Fly to

Guayaquil

Route

Depart

Return

Price

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Fri 7/25

6:10 pm-10:40 pm

1 stop5h 30m

Guayaquil Jose Joaquin de Olmedo

Thu 7/31

12:04 am-3:28 pm

1 stop14h 24m

$400

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Fri 7/4

2:07 pm-8:30 pm

1 stop7h 23m

Guayaquil Jose Joaquin de Olmedo

Tue 7/8

6:31 pm-10:59 am

1 stop15h 28m

$407

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Fri 8/8

6:10 pm-11:20 pm

1 stop6h 10m

Guayaquil Jose Joaquin de Olmedo

Tue 8/12

4:15 am-10:50 am

1 stop5h 35m

$424

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Thu 6/26

2:05 pm-10:20 pm

1 stop9h 15m

$150

Santo DomingoGuayaquil

SDQ - GYE

SDQGYE

Santo Domingo Las Americas

Thu 8/7

11:45 am-11:20 pm

1 stop12h 35m

$191

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Santo Domingo to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Guayaquil

How far ahead should I book a flight from Santo Domingo to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Guayaquil. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Guayaquil, you should look to book at least 45 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $440). Flying from Santo Domingo to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to GYE?

Find hourly flight availability from Santo Domingo to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Santo Domingo to Guayaquil, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 30% versus a flight in the morning.

Rainfall in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

Temperature in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,345 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Guayaquil round-trip?

    According to our current data, Copa Airlines ($407), Avianca ($424), and Delta ($7,472) offers the cheapest pricing from Santo Domingo to Guayaquil. These flights start at 1% lower than the current average price 3 months from now.

  • Can I find deals for flights from Santo Domingo to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Guayaquil.

  • Can I find deals for business class flights from Santo Domingo to Guayaquil?

    Yes. Cheapflights offers flight deals from Santo Domingo to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Guayaquil (average of $440). Flying from Santo Domingo to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Guayaquil

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Top 2 airlines flying from Santo Domingo to Guayaquil

Discover the top 2 airlines that operate flights from Santo Domingo to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$344Average$430FlexibilityNo cancel feeOn-time70%
AviancaCheapest$390Average$420FlexibilityNo cancel feeOn-time71%

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