HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$75+ Cheap flights from Durham, NC to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GYE
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Durham to Guayaquil Jose Joaquin de Olmedo are usually found in November or January, booked 51 days in advance, depart on a Wednesday or Monday and return on a Sunday

Cheap flight deals from Durham to Guayaquil

Cheapest flights from Durham to Guayaquil
Explore the most affordable flight options available from Durham to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:10 amRDU - GYE
2 stops11h 26mUnited Airlines
Wed 1/1412:20 pmGYE - RDU
2 stops27h 20mUnited Airlines
Deal found 12/15$755
This JetBlue deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:19 pmRDU - GYE
1 stop12h 01mJetBlue
Wed 1/147:45 amGYE - RDU
1 stop13h 40mJetBlue
Deal found 12/14$842
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:10 amRDU - GYE
2 stops11h 26mCopa Airlines
Tue 1/134:33 amGYE - RDU
1 stop8h 42mCopa Airlines
Deal found 12/15$916
This KAYAK deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:51 amRDU - GYE
1 stop12h 02mSpirit Airlines
Thu 1/112:49 amGYE - RDU
1 stop16h 06mSpirit Airlines
Deal found 12/14$1,264
This KAYAK deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:50 pmRDU - GYE
1 stop30h 03mSpirit Airlines
Sat 1/312:49 amGYE - RDU
1 stop16h 06mSpirit Airlines
Deal found 12/13$1,357
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:11 pmRDU - GYE
1 stop8h 30mCopa Airlines
Sun 1/48:34 amGYE - RDU
2 stops25h 05mCopa Airlines
Deal found 12/13$1,475
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:40 pmRDU - GYE
2 stops17h 54mCopa Airlines
Fri 1/28:34 amGYE - RDU
2 stops25h 05mCopa Airlines
Deal found 12/14$1,533

Find flight deals from Durham to Guayaquil

Keep the following information in mind while searching for Durham to Guayaquil flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$267
(Cheapflightsfares)

One-way from

$75
(Priceline)

Popular in

April

Cheapest in

November

Average price

$615
Provider with most accurate pricing for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Durham to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Durham to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Durham to Guayaquil that are best for you.

Fly from

Durham

Fly to

Guayaquil

Route

Depart

Return

Price

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 2/2

2:45 pm-5:16 am

1 stop14h 31m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

7:45 am-9:25 pm

1 stop13h 40m

$296

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Tue 1/13

6:45 am-3:35 pm

1 stop8h 50m

Guayaquil Jose Joaquin de Olmedo

Tue 1/27

7:45 am-9:25 pm

1 stop13h 40m

$304

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 1/28

2:45 pm-5:16 am

1 stop14h 31m

Guayaquil Jose Joaquin de Olmedo

Wed 2/11

7:20 am-9:30 pm

1 stop14h 10m

$317

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 1/9

3:08 pm-12:21 am

1 stop9h 13m

Guayaquil Jose Joaquin de Olmedo

Thu 1/22

1:26 am-2:13 pm

1 stop12h 47m

$321

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 1/9

3:08 pm-12:21 am

1 stop9h 13m

Guayaquil Jose Joaquin de Olmedo

Sun 1/25

1:26 am-6:01 pm

2 stops16h 35m

$345

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 2/9

3:08 pm-12:21 am

1 stop9h 13m

Guayaquil Jose Joaquin de Olmedo

Sun 2/22

12:59 am-12:10 am

2 stops23h 11m

$348

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 1/9

3:08 pm-12:21 am

1 stop9h 13m

Guayaquil Jose Joaquin de Olmedo

Sat 1/24

1:26 am-9:01 pm

2 stops43h 35m

$351

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 2/2

6:15 am-11:42 pm

2 stops17h 27m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

12:20 pm-9:05 pm

2 stops32h 45m

$393

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 1/15

3:08 pm-12:21 am

1 stop9h 13m

$75

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 1/15

9:22 am-12:21 am

2 stops14h 59m

$116

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 13 results
1
2

Best time to book a flight from Durham to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Guayaquil

How far ahead should I book a flight from Durham to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Guayaquil. Price data was last updated on December 12, 2025.

Booking 51 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Guayaquil?

Currently, November is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $181). Flying from Durham to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to GYE?

Find hourly flight availability from Durham to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Durham to Guayaquil, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 29% versus a flight at noon.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated December 15, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Durham to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,557 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,891 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,895 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Durham?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Durham to Guayaquil. 5 airlines have flights to Jose Joaquin de Olmedo from Durham on a regular basis. Booking flights from Durham to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Durham per day.

  • How long is the flight from Durham to Guayaquil?

    JetBlue can get you from Durham to Guayaquil in just under 14h 31m. Your travel time can differ by up to . Airlines will cover a distance of 2627 mi.

  • What are the cheapest airlines to fly from Durham to Guayaquil one-way?

    The cheapest airlines for a one-way flight from Durham to Guayaquil are JetBlue ($160), Copa Airlines ($184), and Delta ($206).

  • Can I find deals for flights from Durham to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Durham to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Guayaquil.

  • Can I find deals for business class flights from Durham to Guayaquil?

    Yes. Cheapflights offers flight deals from Durham to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Guayaquil?

    Currently, November is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $181). Flying from Durham to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Durham to Guayaquil

Discover the top 5 airlines that operate flights from Durham to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$197Average$485FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$201Average$487FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$279Average$454FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$394Average$557FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$541Average$712FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.