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Guayaquil

$176+ Cheap flights from Durham, NC to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GYE
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Guayaquil Jose Joaquin de Olmedo are usually found in November or September, booked 51 days in advance, depart on a Wednesday or Monday and return on a Sunday

Find flight deals from Durham to Guayaquil

Cheapest flights from Durham to Guayaquil
Explore the most affordable flight options available from Durham to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:48 pmRDU - GYE
2 stops27h 55mUnited Airlines
Thu 1/1512:20 pmGYE - RDU
2 stops23h 54mUnited Airlines
Deal found 10/30$384
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:14 pmRDU - GYE
1 stop20h 04mCopa Airlines
Tue 11/186:37 pmGYE - RDU
1 stop18h 50mCopa Airlines
Deal found 10/28$431
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/84:48 pmRDU - GYE
2 stops30h 53mUnited Airlines
Tue 1/2012:20 pmGYE - RDU
2 stops23h 54mUnited Airlines
Deal found 10/29$447
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:15 amRDU - GYE
1 stop8h 06mJetBlue
Tue 1/204:45 pmGYE - RDU
1 stop30h 14mJetBlue
Deal found 10/29$463
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amRDU - GYE
2 stops17h 06mAmerican Airlines
Tue 11/186:00 amGYE - RDU
2 stops17h 25mAmerican Airlines
Deal found 10/28$469
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:20 pmRDU - GYE
1 stop25h 00mJetBlue
Tue 11/183:40 pmGYE - RDU
1 stop20h 25mJetBlue
Deal found 10/29$495
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:05 pmRDU - GYE
2 stops34h 15mMultiple Airlines
Tue 11/186:37 pmGYE - RDU
1 stop18h 50mMultiple Airlines
Deal found 10/29$511
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:38 amRDU - GYE
2 stops16h 28mAmerican Airlines
Fri 12/56:10 amGYE - RDU
2 stops16h 38mAmerican Airlines
Deal found 10/30$520
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:30 pmRDU - GYE
1 stop23h 51mJetBlue
Thu 1/154:45 pmGYE - RDU
1 stop30h 14mJetBlue
Deal found 10/30$523
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:00 pmRDU - GYE
1 stop25h 20mJetBlue
Fri 12/54:31 pmGYE - RDU
1 stop22h 19mJetBlue
Deal found 10/30$530
This LATAM Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:05 amRDU - GYE
2 stops14h 18mLATAM Airlines
Wed 11/196:10 amGYE - RDU
2 stops14h 17mLATAM Airlines
Deal found 10/29$531

Cheap flight deals from Durham to Guayaquil

Keep the following information in mind while searching for Durham to Guayaquil flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$384
(United Airlines)

One-way from

$218
(American Airlines)

Popular in

December

Cheapest in

November

Average price

$505
Provider with most accurate pricing for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Durham to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Durham to Guayaquil Jose Joaquin de Olmedo
Search Deals
High demand for flights, 7% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Durham to Guayaquil that are best for you.

Fly from

Durham

Fly to

Guayaquil

Route

Depart

Return

Price

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 12/5

4:48 pm-11:41 pm

2 stops30h 53m

Guayaquil Jose Joaquin de Olmedo

Thu 1/15

12:20 pm-12:14 pm

2 stops23h 54m

$384

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 12/8

4:48 pm-11:41 pm

2 stops30h 53m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

12:20 pm-12:14 pm

2 stops23h 54m

$447

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Tue 4/28

2:00 pm-7:20 am

1 stop18h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 4/29

4:00 pm-9:50 am

1 stop16h 50m

$504

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 11/13

8:05 am-10:23 pm

2 stops14h 18m

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

6:10 am-8:27 pm

2 stops14h 17m

$531

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Tue 4/28

5:29 am-1:33 pm

2 stops9h 04m

Guayaquil Jose Joaquin de Olmedo

Wed 4/29

2:33 pm-11:54 am

2 stops20h 21m

$587

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 12/5

5:50 pm-11:43 pm

1 stop29h 53m

Guayaquil Jose Joaquin de Olmedo

Wed 1/14

12:59 am-4:24 pm

1 stop15h 25m

$600

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 12/8

8:05 am-5:53 pm

2 stops33h 48m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

4:30 pm-10:18 am

1 stop17h 48m

$624

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 11/24

3:14 pm-11:41 pm

1 stop8h 27m

Guayaquil Jose Joaquin de Olmedo

Fri 1/9

4:33 am-1:15 pm

1 stop8h 42m

$636

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 12/24

5:50 pm-11:53 pm

1 stop30h 03m

$176

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 12/24

6:10 am-8:43 pm

2 stops14h 33m

$211

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 17 results
1
2

Best time to book a flight from Durham to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Guayaquil

How far ahead should I book a flight from Durham to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Guayaquil. Price data was last updated on October 24, 2025.

Booking 51 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Guayaquil?

Currently, November is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $181). Flying from Durham to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to GYE?

Find hourly flight availability from Durham to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

When flying from Durham to Guayaquil, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 29% versus a flight at noon.

How much does it cost to fly round-trip from Durham to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated October 30, 2025.
See what other customers who have flown with Copa Airlines, LATAM Airlines, and American Airlines from Durham to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
LATAM Airlines
7.5
Good
1,873 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
American Airlines
7.2
Good
11,035 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
JetBlue
7.2
Good
2,906 reviews
Copa Airlines
7.6
Good
1,561 reviews

Food

6.9

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Durham to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Durham?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Durham to Guayaquil. 4 airlines have flights to Jose Joaquin de Olmedo from Durham on a regular basis. Booking flights from Durham to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Durham per day.

  • How long is the flight from Durham to Guayaquil?

    United Airlines, LATAM Airlines, and American Airlines can get you from Durham to Guayaquil in just under 9h 04m. Your travel time can differ by up to 21h 49m. Airlines will cover a distance of 2627 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Durham to Guayaquil one-way?

    The cheapest airlines for a one-way flight from Durham to Guayaquil are Spirit Airlines ($176), United Airlines ($211), and American Airlines ($218).

  • Can I find deals for flights from Durham to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Durham to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Guayaquil.

  • Can I find deals for business class flights from Durham to Guayaquil?

    Yes. Cheapflights offers flight deals from Durham to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Guayaquil?

    Currently, November is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $181). Flying from Durham to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Durham to Guayaquil

Discover the top 4 airlines that operate flights from Durham to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$231Average$486FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$279Average$450FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$394Average$584FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$541Average$681FlexibilityNo cancel feeOn-time71%

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