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Guayaquil

$147+ Cheap flights from Durham, NC to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GYE
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Guayaquil Jose Joaquin de Olmedo are usually found in November or August, booked 51 days in advance, depart on a Wednesday or Monday and return on a Sunday

Cheap flight deals from Durham to Guayaquil

Keep the following information in mind while searching for Durham to Guayaquil flight deals. Data was last updated September 15, 2025.

Round-trip from

$393
(United Airlines)

One-way from

$147
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$399
From Durham to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Durham to Guayaquil Jose Joaquin de Olmedo
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High demand for flights, 4% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Durham to Guayaquil

Cheapest flights from Durham to Guayaquil
Explore the most affordable flight options available from Durham to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:04 amRDU - GYE
2 stops31h 30mUnited Airlines
Fri 12/58:30 amGYE - RDU
2 stops13h 45mUnited Airlines
Deal found 9/14$393
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:19 pmRDU - GYE
1 stop8h 34mCopa Airlines
Wed 11/56:02 amGYE - RDU
1 stop7h 25mCopa Airlines
Deal found 9/14$417
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:35 pmRDU - GYE
1 stop25h 45mJetBlue
Fri 12/54:31 pmGYE - RDU
1 stop29h 41mJetBlue
Deal found 9/14$442
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:40 pmRDU - GYE
2 stops24h 30mAmerican Airlines
Fri 10/318:15 amGYE - RDU
2 stops25h 14mAmerican Airlines
Deal found 9/13$457
This KAYAK deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/13:11 pmRDU - GYE
1 stop8h 30mCopa Airlines
Sun 12/144:32 amGYE - RDU
1 stop8h 53mCopa Airlines
Deal found 9/12$459
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:07 amRDU - GYE
2 stops18h 30mUnited Airlines
Wed 11/52:35 pmGYE - RDU
2 stops55h 19mUnited Airlines
Deal found 9/14$462
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:05 amRDU - GYE
2 stops14h 18mDelta
Fri 12/54:30 pmGYE - RDU
1 stop17h 22mDelta
Deal found 9/14$482
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:15 amRDU - GYE
1 stop7h 15mJetBlue
Sun 10/52:40 pmGYE - RDU
1 stop30h 30mJetBlue
Deal found 9/13$497
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:35 pmRDU - GYE
1 stop26h 45mJetBlue
Mon 11/33:30 pmGYE - RDU
1 stop20h 17mJetBlue
Deal found 9/15$515
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:31 amRDU - GYE
3 stops17h 10mUnited Airlines
Mon 1/198:34 amGYE - RDU
2 stops13h 56mUnited Airlines
Deal found 9/12$516
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:14 pmRDU - GYE
1 stop8h 41mCopa Airlines
Fri 11/286:02 amGYE - RDU
1 stop7h 25mCopa Airlines
Deal found 9/13$518

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Durham to Guayaquil that are best for you.

Fly from

Durham

Fly to

Guayaquil

Route

Depart

Return

Price

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Sat 11/15

6:04 am-1:34 pm

2 stops31h 30m

Guayaquil Jose Joaquin de Olmedo

Fri 12/5

8:30 am-10:15 pm

2 stops13h 45m

$393

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 10/29

6:07 am-11:37 pm

2 stops18h 30m

Guayaquil Jose Joaquin de Olmedo

Wed 11/5

2:35 pm-9:54 pm

2 stops55h 19m

$462

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 10/2

7:05 am-1:46 pm

2 stops31h 41m

Guayaquil Jose Joaquin de Olmedo

Fri 10/24

12:15 pm-10:14 pm

2 stops32h 59m

$544

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 12/5

7:15 am-3:21 pm

1 stop8h 06m

Guayaquil Jose Joaquin de Olmedo

Thu 1/15

3:40 pm-5:00 pm

1 stop25h 20m

$547

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 12/5

5:19 pm-11:45 pm

1 stop30h 26m

Guayaquil Jose Joaquin de Olmedo

Wed 1/14

12:59 am-4:24 pm

1 stop15h 25m

$567

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 12/8

7:15 am-3:21 pm

1 stop8h 06m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

3:40 pm-5:00 pm

1 stop25h 20m

$578

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 10/2

6:30 pm-7:48 pm

1 stop26h 18m

Guayaquil Jose Joaquin de Olmedo

Sun 10/5

8:20 am-8:11 am

2 stops22h 51m

$601

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 12/8

7:15 am-1:40 am

2 stops18h 25m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

4:30 pm-9:54 am

1 stop17h 24m

$601

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Mon 12/8

5:19 pm-11:45 pm

1 stop30h 26m

$147

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 10/2

9:23 am-8:35 am

2 stops24h 12m

$156

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 16 results
1
2

Best time to book a flight from Durham to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Guayaquil

How far ahead should I book a flight from Durham to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Guayaquil. Price data was last updated on September 12, 2025.

Booking 51 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $440). Flying from Durham to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to GYE?

Find hourly flight availability from Durham to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Durham to Guayaquil as you normally would.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 15, 2025.
See what other customers who have flown with Copa Airlines, LATAM Airlines, and American Airlines from Durham to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.6

Food

6.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.6

Food

6.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
LATAM Airlines
7.5
Good
1,847 reviews
Copa Airlines
7.6
Good
1,531 reviews

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.6

Food

6.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,531 reviews

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.6

Food

6.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
JetBlue
7.2
Good
2,912 reviews
Copa Airlines
7.6
Good
1,531 reviews

Crew

8.1

Comfort

7.4

Boarding

7.8

Overall

7.6

Food

6.8

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Durham to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Durham?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Durham to Guayaquil. 4 airlines have flights to Jose Joaquin de Olmedo from Durham on a regular basis. Booking flights from Durham to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Durham per day.

  • How long is the flight from Durham to Guayaquil?

    United Airlines can get you from Durham to Guayaquil in just under 31h 30m. Your travel time can differ by up to . Airlines will cover a distance of 2627 mi.

  • Can I find deals for flights from Durham to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Durham to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Guayaquil.

  • Can I find deals for business class flights from Durham to Guayaquil?

    Yes. Cheapflights offers flight deals from Durham to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $440). Flying from Durham to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Durham to Guayaquil

Discover the top 4 airlines that operate flights from Durham to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$231Average$487FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$279Average$436FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$394Average$584FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$517Average$636FlexibilityNo cancel feeOn-time71%

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