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Guayaquil

$94+ Cheap flights from Durham, NC to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GYE
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Durham to Guayaquil

Cheapest flights from Durham to Guayaquil
Explore the most affordable flight options available from Durham to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:04 pm
RDU
-
GYE
1 stop9h 16m
Multiple Airlines
Mon 3/1611:59 pm
GYE
-
RDU
1 stop17h 45m
Multiple Airlines
Deal found 1/26$296
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
-
GYE
2 stops29h 14m
Multiple Airlines
Tue 3/1711:59 pm
GYE
-
RDU
1 stop17h 45m
Multiple Airlines
Deal found 1/26$297
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
-
GYE
2 stops29h 14m
Multiple Airlines
Mon 3/1611:59 pm
GYE
-
RDU
1 stop17h 45m
Multiple Airlines
Deal found 1/26$298
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:04 pm
RDU
-
GYE
1 stop9h 16m
Multiple Airlines
Tue 3/1711:59 pm
GYE
-
RDU
2 stops16h 30m
Multiple Airlines
Deal found 1/26$302
This KAYAK deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/193:08 pm
RDU
-
GYE
1 stop8h 56m
Spirit Airlines
Tue 3/1711:59 pm
GYE
-
RDU
1 stop17h 45m
Spirit Airlines
Deal found 1/26$308
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:04 pm
RDU
-
GYE
1 stop9h 16m
Multiple Airlines
Thu 3/1911:59 pm
GYE
-
RDU
1 stop17h 45m
Multiple Airlines
Deal found 1/26$309
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/203:12 pm
RDU
-
GYE
1 stop8h 43m
Multiple Airlines
Tue 3/1711:59 pm
GYE
-
RDU
1 stop17h 45m
Multiple Airlines
Deal found 1/26$310
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/163:08 pm
RDU
-
GYE
1 stop8h 56m
Spirit Airlines
Mon 3/1611:59 pm
GYE
-
RDU
1 stop17h 45m
Spirit Airlines
Deal found 1/26$311
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/153:08 pm
RDU
-
GYE
1 stop8h 56m
Spirit Airlines
Tue 3/1711:59 pm
GYE
-
RDU
1 stop17h 45m
Spirit Airlines
Deal found 1/26$315
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/153:08 pm
RDU
-
GYE
1 stop8h 56m
Spirit Airlines
Mon 3/1611:59 pm
GYE
-
RDU
1 stop17h 45m
Spirit Airlines
Deal found 1/26$316

Find flight deals from Durham to Guayaquil

Keep the following information in mind while searching for Durham to Guayaquil flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$296
(Kiwi.com)

One-way from

$94
(Priceline)

Popular in

April

Cheapest in

November

Average price

$366
Provider with most accurate pricing for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Durham to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Durham to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Durham to Guayaquil that are best for you.

Fly from

Durham

Fly to

Guayaquil

Route

Depart

Return

Price

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Sat 2/21

8:04 pm-5:20 am

1 stop9h 16m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-6:44 pm

1 stop17h 45m

$296

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 2/20

3:12 pm-11:55 pm

1 stop8h 43m

Guayaquil Jose Joaquin de Olmedo

Tue 3/17

11:59 pm-6:44 pm

1 stop17h 45m

$310

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Fri 2/20

3:12 pm-11:55 pm

1 stop8h 43m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-6:44 pm

1 stop17h 45m

$310

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Sun 2/15

3:08 pm-12:04 am

1 stop8h 56m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-6:44 pm

1 stop17h 45m

$316

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 3/26

6:00 am-11:04 pm

2 stops18h 04m

Guayaquil Jose Joaquin de Olmedo

Tue 4/7

11:59 pm-6:44 pm

1 stop17h 45m

$328

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Sat 2/21

8:04 pm-5:20 am

1 stop9h 16m

Guayaquil Jose Joaquin de Olmedo

Wed 3/18

11:59 pm-6:44 pm

1 stop17h 45m

$331

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Thu 2/19

3:08 pm-12:04 am

1 stop8h 56m

Guayaquil Jose Joaquin de Olmedo

Thu 3/19

11:59 pm-6:44 pm

1 stop17h 45m

$335

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 2/18

5:46 pm-5:18 am

1 stop11h 32m

Guayaquil Jose Joaquin de Olmedo

Wed 3/18

11:59 pm-6:44 pm

1 stop17h 45m

$339

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 2/18

5:46 pm-5:18 am

1 stop11h 32m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

6:25 am-11:23 pm

1 stop15h 58m

$340

RaleighGuayaquil

RDU - GYE

RDUGYE

Raleigh-Durham

Wed 2/18

5:46 pm-5:18 am

1 stop11h 32m

Guayaquil Jose Joaquin de Olmedo

Tue 3/17

6:25 am-11:23 pm

1 stop15h 58m

$340

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 16 results
1
2

Best time to book a flight from Durham to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Guayaquil

How far ahead should I book a flight from Durham to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Guayaquil. Price data was last updated on January 23, 2026.

Booking 51 days in advance of your planned departure date is, on average, the best time to get cheap flights from Durham to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Durham to Guayaquil?

Currently, November is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $181). Flying from Durham to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated January 29, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Durham to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,127 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,918 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,560 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,206 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,891 reviews
Delta
7.9
Good
8,127 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Durham?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Durham to Guayaquil. 5 airlines have flights to Jose Joaquin de Olmedo from Durham on a regular basis. Booking flights from Durham to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Durham per day.

  • How long is the flight from Durham to Guayaquil?

    Spirit Airlines can get you from Durham to Guayaquil in just under 8h 56m. Your travel time can differ by up to . Airlines will cover a distance of 2627 mi.

  • What are the cheapest airlines to fly from Durham to Guayaquil one-way?

    The cheapest airlines for a one-way flight from Durham to Guayaquil are JetBlue ($160), Copa Airlines ($184), and Delta ($206).

  • Can I find deals for flights from Durham to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Durham to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Guayaquil.

  • Can I find deals for business class flights from Durham to Guayaquil?

    Yes. Cheapflights offers flight deals from Durham to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Guayaquil?

    Currently, November is the cheapest month in which you can book a flight from Durham to Guayaquil (average of $181). Flying from Durham to Guayaquil in May is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Durham to Guayaquil

Discover the top 5 airlines that operate flights from Durham to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$197Average$436FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$201Average$326FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$266Average$433FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$389Average$734FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$394Average$584FlexibilityNo cancel feeOn-time81%

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