HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$217+ Cheap flights from Columbus to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — GYE
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbus to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbus to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$490
(Avianca Connect)

One-way from

$217
(Kiwi.com)

Popular in

July

Cheapest in

March

Average price

$747
From Columbus to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Columbus to Guayaquil Jose Joaquin de Olmedo
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Columbus to Guayaquil

Cheapest flights from Columbus to Guayaquil
Explore the most affordable flight options available from Columbus to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:15 amCMH - GYE
2 stops19h 05mMultiple Airlines
Sat 10/254:15 amGYE - CMH
2 stops13h 23mMultiple Airlines
Deal found 9/14$490
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:15 amCMH - GYE
2 stops33h 25mMultiple Airlines
Tue 10/214:15 amGYE - CMH
3 stops26h 22mMultiple Airlines
Deal found 9/15$587
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:21 pmCMH - GYE
3 stops39h 54mMultiple Airlines
Wed 11/53:30 amGYE - CMH
2 stops17h 42mMultiple Airlines
Deal found 9/15$590
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amCMH - GYE
2 stops18h 40mMultiple Airlines
Tue 10/144:15 amGYE - CMH
3 stops33h 14mMultiple Airlines
Deal found 9/15$601
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:00 amCMH - GYE
2 stops29h 15mMultiple Airlines
Wed 11/53:35 pmGYE - CMH
2 stops29h 37mMultiple Airlines
Deal found 9/14$612
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:30 amCMH - GYE
2 stops17h 11mUnited Airlines
Sun 12/712:20 pmGYE - CMH
2 stops30h 55mUnited Airlines
Deal found 9/15$636
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:50 amCMH - GYE
2 stops24h 28mMultiple Airlines
Sat 12/612:59 amGYE - CMH
1 stop8h 56mMultiple Airlines
Deal found 9/14$646

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Columbus to Guayaquil that are best for you.

Fly from

Columbus

Fly to

Guayaquil

Route

Depart

Return

Price

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

5:15 am-11:20 pm

2 stops19h 05m

Guayaquil Jose Joaquin de Olmedo

Sat 10/25

4:15 am-6:38 pm

2 stops13h 23m

$490

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

5:15 am-1:40 pm

2 stops33h 25m

Guayaquil Jose Joaquin de Olmedo

Mon 10/20

3:35 am-7:37 am

3 stops27h 02m

$587

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Thu 10/30

6:21 pm-9:15 am

3 stops39h 54m

Guayaquil Jose Joaquin de Olmedo

Wed 11/5

3:30 am-9:12 pm

2 stops17h 42m

$590

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 10/31

6:21 pm-2:30 pm

3 stops45h 09m

Guayaquil Jose Joaquin de Olmedo

Wed 11/5

6:55 pm-9:12 pm

2 stops26h 17m

$590

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Thu 11/27

6:30 am-1:34 pm

2 stops31h 04m

Guayaquil Jose Joaquin de Olmedo

Sun 12/7

12:20 pm-10:29 pm

2 stops34h 09m

$636

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

5:15 am-8:35 am

2 stops28h 20m

Guayaquil Jose Joaquin de Olmedo

Fri 10/24

2:50 pm-11:58 am

3 stops20h 08m

$653

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 9/30

5:15 am-8:35 am

2 stops28h 20m

$217

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 12/15

10:50 am-11:45 pm

1 stop12h 55m

$344

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 10/31

6:30 am-11:18 am

2 stops29h 48m

$406

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 9/30

6:40 am-7:48 pm

1 stop14h 08m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 12 results
1
2

Best time to book a flight from Columbus to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Guayaquil

What is the cheapest month to book a flight from Columbus to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Columbus to Guayaquil (average of $440). Flying from Columbus to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Columbus to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Columbus to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Columbus?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Columbus to Guayaquil. 1 airline have flights to Jose Joaquin de Olmedo from Columbus on a regular basis. Booking flights from Columbus to Guayaquil Jose Joaquin de Olmedo should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.

  • What is the cheapest airline to fly from Columbus to Guayaquil round-trip?

    Currently priced at $655, American Airlines will fly you from Columbus to Guayaquil and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. You may be able to fly from Columbus to Guayaquil for 17% less than the average price by searching for this airline.

  • Can I find deals for flights from Columbus to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Columbus to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Guayaquil.

  • Can I find deals for business class flights from Columbus to Guayaquil?

    Yes. Cheapflights offers flight deals from Columbus to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Columbus to Guayaquil (average of $440). Flying from Columbus to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Columbus to Guayaquil

Discover the top airline that operate flights from Columbus to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$655Average$825FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.