$316+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Jul 4 — Jul 111
Round-trip
1 adult, Economy
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Best
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Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
This Trip.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:36 pm
CLE
- GYE
2 stops17h 19m
Multiple Airlines
Fri 7/103:30 am
GYE
- CLE
2 stops19h 08m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$563
This Ovago deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Sat 7/251:27 pm
GYE
- CLE
1 stop9h 28m
JetBlue
Deal found 6/3![JetBlue logo]()
$581
This JetBlue deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:00 am
CLE
- GYE
1 stop8h 20m
JetBlue
Wed 8/261:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 6/2![JetBlue logo]()
$585
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:05 pm
CLE
- GYE
2 stops32h 33m
Multiple Airlines
Sat 7/256:45 pm
GYE
- CLE
1 stop27h 53m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$610
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Mon 8/171:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 6/2![JetBlue logo]()
$694
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
This Trip.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:36 pm
CLE
- GYE
2 stops17h 19m
Multiple Airlines
Fri 7/103:30 am
GYE
- CLE
2 stops19h 08m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$563
This Ovago deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Sat 7/251:27 pm
GYE
- CLE
1 stop9h 28m
JetBlue
Deal found 6/3![JetBlue logo]()
$581
This JetBlue deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:00 am
CLE
- GYE
1 stop8h 20m
JetBlue
Wed 8/261:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 6/2![JetBlue logo]()
$585
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:05 pm
CLE
- GYE
2 stops32h 33m
Multiple Airlines
Sat 7/256:45 pm
GYE
- CLE
1 stop27h 53m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$610
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Mon 8/171:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 6/2![JetBlue logo]()
$694
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated June 4, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated June 4, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:36 pm
CLE
- GYE
2 stops17h 19m
Multiple Airlines
Fri 7/103:30 am
GYE
- CLE
2 stops19h 08m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$563
This Ovago deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Sat 7/251:27 pm
GYE
- CLE
1 stop9h 28m
JetBlue
Deal found 6/3![JetBlue logo]()
$581
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:05 pm
CLE
- GYE
2 stops32h 33m
Multiple Airlines
Sat 7/256:45 pm
GYE
- CLE
1 stop27h 53m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$610
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Mon 8/171:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 6/2![JetBlue logo]()
$694
This KAYAK deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:26 am
CLE
- GYE
2 stops15h 27m
Copa Airlines
Mon 8/1712:22 pm
GYE
- CLE
2 stops22h 06m
Copa Airlines
Deal found 5/31![Copa Airlines logo]()
$861
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:05 pm
CLE
- GYE
2 stops26h 30m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$316
This JetBlue deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:50 am
CLE
- GYE
1 stop8h 32m
JetBlue
Deal found 6/1![JetBlue logo]()
$341
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:03 am
CLE
- GYE
2 stops13h 34m
American Airlines
Deal found 6/1![American Airlines logo]()
$588
This oojo deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am
CLE
- GYE
1 stop26h 45m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$790
This BusinessClass deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:12 am
CLE
- GYE
2 stops18h 25m
Copa Airlines
Deal found 6/3![Copa Airlines logo]()
$844
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:28 am
CLE
- GYE
1 stop8h 05m
American Airlines
Deal found 6/3![American Airlines logo]()
$854
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:13 pm
CLE
- GYE
2 stops18h 20m
American Airlines
Deal found 6/3![American Airlines logo]()
$864
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:07 pm
CLE
- GYE
3 stops43h 08m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$6,346
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 4, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $563 (Trip.com) |
One-way from | $316 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 7/4
4:36 pm-8:55 am
2 stops17h 19m
Guayaquil Jose Joaquin de Olmedo
Fri 7/10
3:30 am-11:38 pm
2 stops19h 08m
$563
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 7/18
7:50 am-3:22 pm
1 stop8h 32m
Guayaquil Jose Joaquin de Olmedo
Sat 7/25
1:27 pm-11:55 pm
1 stop9h 28m
$581
Quickest round-trip
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 8/22
8:00 am-3:20 pm
1 stop8h 20m
Guayaquil Jose Joaquin de Olmedo
Wed 8/26
1:25 pm-11:59 pm
1 stop9h 34m
$585
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 7/18
4:05 pm-11:38 pm
2 stops32h 33m
Guayaquil Jose Joaquin de Olmedo
Sat 7/25
6:45 pm-11:38 pm
1 stop27h 53m
$610
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Thu 7/23
7:50 am-3:22 pm
1 stop8h 32m
Guayaquil Jose Joaquin de Olmedo
Mon 8/17
1:25 pm-11:59 pm
1 stop9h 34m
$694
Cheapest one-way
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 7/11
4:05 pm-5:35 pm
2 stops26h 30m
$316
Quickest one-way
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 7/11
7:50 am-3:22 pm
1 stop8h 32m
$341
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Fri 10/23
6:00 am-10:40 am
1 stop29h 40m
$790
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Thu 10/22
6:00 am-7:45 am
1 stop26h 45m
$790
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Thu 10/22
6:12 am-11:37 pm
2 stops18h 25m
$844
Showing 1-10 of 11 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated June 4, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Comfort
7.2
Boarding
7.5
Food
6.4
Overall
7.1
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Crew
7.9
Comfort
7.2
Boarding
7.5
Food
6.4
Overall
7.1
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 4, 2026.
Cleveland and Guayaquil flights
Browse other Cleveland and Guayaquil flight options. Last updated on June 4, 2026.
Other flights from Cleveland
Browse through other flights departing from Cleveland. Flights are based on user searches made on Cheapflights and were last updated on June 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Cleveland to Guayaquil
Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$540 | Average$746 | FlexibilityNo cancel fee | On-time71% |