$170+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Sep 18 — Sep 251
Round-trip
1 adult, Economy
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Find cheap flights from Cleveland to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cleveland to Guayaquil
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Best
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One-way
Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
This JetBlue deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 22m
Fri 10/161:30 pm -
1 stop9h 29m
Deal found 8/18![JetBlue logo]()
$644
This deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:50 am -
1 stop8h 32m
Sat 9/1212:30 pm -
1 stop10h 02m
Deal found 8/14![JetBlue logo]()
$855
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:00 am -
2 stops17h 37m
Fri 10/1612:18 pm -
2 stops30h 48m
Deal found 8/18![United Airlines logo]()
$992
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:30 am -
1 stop18h 25m
Mon 1/43:30 pm -
1 stop26h 26m
Deal found 8/19![American Airlines logo]()
$1,370
This KAYAK deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:59 pm -
2 stops26h 58m
Mon 1/42:44 pm -
2 stops31h 07m
Deal found 8/19![Copa Airlines logo]()
$1,398
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:41 am -
3 stops34h 39m
Fri 10/1610:05 am -
2 stops22h 36m
Deal found 8/18![Avianca logo]()
$1,400
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:51 pm -
2 stops19h 39m
Sun 1/36:00 am -
2 stops16h 57m
Deal found 8/18![American Airlines logo]()
$1,495
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
This JetBlue deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 22m
Fri 10/161:30 pm -
1 stop9h 29m
Deal found 8/18![JetBlue logo]()
$644
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:00 am -
2 stops17h 37m
Fri 10/1612:18 pm -
2 stops30h 48m
Deal found 8/18![United Airlines logo]()
$992
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:30 am -
1 stop18h 25m
Mon 1/43:30 pm -
1 stop26h 26m
Deal found 8/19![American Airlines logo]()
$1,370
This Avianca deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:41 am -
3 stops34h 39m
Fri 10/1610:05 am -
2 stops22h 36m
Deal found 8/18![Avianca logo]()
$1,400
This deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:50 am -
1 stop8h 32m
Sat 9/1212:30 pm -
1 stop10h 02m
Deal found 8/14![JetBlue logo]()
$855
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 19, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 19, 2026 and is based on user searches.
This deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:50 am -
1 stop8h 32m
Sat 9/1212:30 pm -
1 stop10h 02m
Deal found 8/14![JetBlue logo]()
$855
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:45 pm -
2 stops32h 52m
Deal found 8/16![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/203:45 pm -
2 stops32h 52m
Deal found 8/18![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:45 pm -
2 stops43h 49m
Deal found 8/18![Multiple Airlines logo]()
$192
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am -
1 stop9h 14m
Deal found 8/18![JetBlue logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:10 am -
3 stops55h 20m
Deal found 8/18![Multiple Airlines logo]()
$257
This Cheapflightsfares deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am -
1 stop9h 14m
Deal found 8/16![JetBlue logo]()
$295
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:00 am -
1 stop9h 14m
Deal found 8/18![JetBlue logo]()
$345
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 19, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $644 (JetBlue) |
One-way from | $170 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 19, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 10/12
8:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
1:30 pm-11:59 pm
1 stop9h 29m
$644
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 8/30
7:50 am-3:22 pm
1 stop8h 32m
Guayaquil Jose Joaquin de Olmedo
Sat 9/12
12:30 pm-11:32 pm
1 stop10h 02m
$855
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 10/12
7:00 am-11:37 pm
2 stops17h 37m
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
12:18 pm-8:06 pm
2 stops30h 48m
$992
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 12/19
5:30 am-11:55 pm
1 stop18h 25m
Guayaquil Jose Joaquin de Olmedo
Mon 1/4
3:30 pm-5:56 pm
1 stop26h 26m
$1,370
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 10/12
10:41 am-8:20 pm
3 stops34h 39m
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
10:05 am-9:41 am
2 stops22h 36m
$1,400
Cheapest one-way
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 9/14
3:45 pm-11:37 pm
2 stops32h 52m
$170
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 9/20
3:45 pm-11:37 pm
2 stops32h 52m
$171
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Fri 9/18
3:45 pm-10:34 am
2 stops43h 49m
$192
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 9/19
7:00 am-10:34 am
2 stops28h 34m
$192
Quickest one-way
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 9/19
7:00 am-3:14 pm
1 stop9h 14m
$245
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 19, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Comfort
7.2
Crew
7.9
Boarding
7.5
Overall
7.1
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Comfort
7.2
Crew
7.9
Boarding
7.5
Overall
7.1
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 19, 2026.
Cleveland and Guayaquil flights
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Top airline flying from Cleveland to Guayaquil
Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$746 | FlexibilityNo cancel fee | On-time71% |