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Guayaquil

$333+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Cleveland to Guayaquil

Cheapest flights from Cleveland to Guayaquil
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:05 pm
CLE
-
GYE
1 stop31h 59m
Multiple Airlines
Sun 6/1411:59 pm
GYE
-
CLE
1 stop21h 55m
Multiple Airlines
Deal found 4/22$413
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:24 pm
CLE
-
GYE
2 stops52h 40m
Multiple Airlines
Thu 6/1811:59 pm
GYE
-
CLE
1 stop13h 39m
Multiple Airlines
Deal found 4/22$465
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:15 am
CLE
-
GYE
1 stop17h 49m
Multiple Airlines
Mon 5/116:50 pm
GYE
-
CLE
2 stops28h 48m
Multiple Airlines
Deal found 4/21$546
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:07 pm
CLE
-
GYE
1 stop19h 27m
American Airlines
Mon 8/176:00 am
GYE
-
CLE
1 stop16h 55m
American Airlines
Deal found 4/21$747
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:44 am
CLE
-
GYE
2 stops17h 53m
American Airlines
Sun 6/146:00 am
GYE
-
CLE
2 stops16h 39m
American Airlines
Deal found 4/22$775
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:03 pm
CLE
-
GYE
1 stop19h 28m
American Airlines
Fri 6/126:00 am
GYE
-
CLE
1 stop16h 59m
American Airlines
Deal found 4/21$806

Find flight deals from Cleveland to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$413
(Kiwi.com)

One-way from

$333
(FlightHub)
Provider with most accurate pricing for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Cleveland Hopkins Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Cleveland Hopkins Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Wed 6/10

7:24 pm-11:04 pm

2 stops28h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 6/14

11:59 pm-10:54 pm

1 stop21h 55m

$451

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 6/11

7:45 am-11:04 pm

1 stop16h 19m

Guayaquil Jose Joaquin de Olmedo

Mon 6/15

6:45 pm-11:43 pm

1 stop27h 58m

$648
Quickest round-trip

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 6/11

7:07 am-10:37 pm

2 stops16h 30m

Guayaquil Jose Joaquin de Olmedo

Mon 6/15

2:31 pm-11:17 am

2 stops19h 46m

$725

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 7/23

7:07 pm-1:34 pm

1 stop19h 27m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

6:00 am-11:55 pm

1 stop16h 55m

$747
Cheapest one-way
Quickest one-way

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Sat 5/16

9:00 am-10:58 am

2 stops26h 58m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cleveland to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 24, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,666 reviews

Boarding

7.5

Food

6.4

Overall

7.1

Entertainment

6.9

Comfort

7.2

Crew

7.9

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,666 reviews
American Airlines
7.1
Good
11,666 reviews

Boarding

7.5

Food

6.4

Overall

7.1

Entertainment

6.9

Comfort

7.2

Crew

7.9

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cleveland to Guayaquil?

    For as low as $725, American Airlines can have you in Guayaquil from Cleveland in 16h 30m. The distance between Cleveland and Guayaquil is about 3011 mi.

  • What is the cheapest airline to fly from Cleveland to Guayaquil round-trip?

    According to our current data, American Airlines ($540), offers the cheapest pricing from Cleveland to Guayaquil.

  • Can I find deals for flights from Cleveland to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cleveland to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Guayaquil.

  • Can I find deals for business class flights from Cleveland to Guayaquil?

    Yes. Cheapflights offers flight deals from Cleveland to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Cleveland to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Cleveland to Guayaquil

Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$540Average$684FlexibilityNo cancel feeOn-time71%

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