$170+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Sep 26 — Oct 31
Round-trip
1 adult, Economy
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Find cheap flights from Cleveland to Guayaquil with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop8h 29m
Fri 10/166:00 am -
1 stop16h 59m
Deal found 8/23![American Airlines logo]()
$544
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:05 am -
2 stops17h 34m
Fri 10/232:29 pm -
2 stops19h 40m
Deal found 8/24![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:55 pm -
1 stop19h 39m
Mon 11/166:00 am -
1 stop11h 50m
Deal found 8/27![American Airlines logo]()
$555
This JetBlue deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 24m
Fri 10/161:30 pm -
1 stop9h 29m
Deal found 8/24![JetBlue logo]()
$594
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:19 am -
1 stop16h 51m
Sat 10/36:00 am -
1 stop16h 46m
Deal found 8/27![American Airlines logo]()
$629
This Trip.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:05 pm -
2 stops27h 05m
Sun 11/297:35 pm -
2 stops14h 24m
Deal found 8/24![Multiple Airlines logo]()
$639
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:05 pm -
1 stop20h 29m
Wed 11/186:00 am -
1 stop16h 55m
Deal found 8/27![American Airlines logo]()
$555
This JetBlue deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 24m
Fri 10/161:30 pm -
1 stop9h 29m
Deal found 8/24![JetBlue logo]()
$594
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:12 am -
2 stops21h 02m
Mon 10/264:19 pm -
1 stop17h 32m
Deal found 8/24![Delta logo]()
$634
This Trip.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:05 pm -
2 stops35h 30m
Sun 11/296:55 pm -
1 stop15h 04m
Deal found 8/24![Multiple Airlines logo]()
$643
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:55 pm -
1 stop19h 39m
Mon 11/166:00 am -
1 stop11h 50m
Deal found 8/27![American Airlines logo]()
$555
This JetBlue deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:00 am -
1 stop8h 24m
Fri 10/231:30 pm -
1 stop9h 29m
Deal found 8/24![JetBlue logo]()
$695
This JetBlue deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:00 am -
1 stop8h 24m
Sun 10/251:30 pm -
1 stop9h 29m
Deal found 8/24![JetBlue logo]()
$746
This JetBlue deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:00 am -
1 stop8h 24m
Sun 10/251:30 pm -
1 stop9h 29m
Deal found 8/24![JetBlue logo]()
$788
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 27, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 27, 2026 and is based on user searches.
This deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:50 am -
1 stop8h 32m
Sat 9/1212:30 pm -
1 stop10h 02m
Deal found 8/23![JetBlue logo]()
$1,689
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
2 stops17h 10m
Fri 10/26:00 am -
2 stops16h 59m
Deal found 8/26![American Airlines logo]()
$719
This Cheapflightsfares deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:00 am -
1 stop9h 14m
Fri 10/212:30 pm -
1 stop10h 02m
Deal found 8/26![JetBlue logo]()
$725
This Mytrip deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:00 pm -
2 stops14h 55m
Fri 10/23:20 pm -
3 stops28h 27m
Deal found 8/26![Multiple Airlines logo]()
$1,859
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:19 am -
1 stop16h 51m
Sat 10/36:00 am -
1 stop16h 46m
Deal found 8/27![American Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:10 am -
2 stops36h 20m
Sat 10/38:24 am -
2 stops47h 43m
Deal found 8/27![United Airlines logo]()
$1,289
This Mytrip deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:45 pm -
2 stops24h 50m
Sat 10/33:15 pm -
3 stops21h 52m
Deal found 8/27![Multiple Airlines logo]()
$1,784
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:46 pm -
2 stops32h 51m
Deal found 8/23![Multiple Airlines logo]()
$170
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:07 pm -
1 stop19h 22m
Deal found 8/23![American Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:59 pm -
3 stops40h 22m
Deal found 8/23![Multiple Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:03 pm -
2 stops19h 27m
Deal found 8/23![American Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/203:38 pm -
3 stops34h 37m
Deal found 8/23![Multiple Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:19 am -
1 stop16h 51m
Deal found 8/23![American Airlines logo]()
$546
This KAYAK deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:30 am -
1 stop18h 25m
Deal found 8/23![GOL logo]()
$677
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 27, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $544 (American Airlines) |
One-way from | $170 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 27, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Tue 11/10
6:05 pm-2:34 pm
1 stop20h 29m
Guayaquil Jose Joaquin de Olmedo
Wed 11/18
6:00 am-10:55 pm
1 stop16h 55m
$555
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 11/9
6:55 pm-2:34 pm
1 stop19h 39m
Guayaquil Jose Joaquin de Olmedo
Mon 11/16
6:00 am-5:50 pm
1 stop11h 50m
$555
Quickest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 10/12
8:00 am-3:24 pm
1 stop8h 24m
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
1:30 pm-11:59 pm
1 stop9h 29m
$594
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Fri 10/23
11:12 am-7:14 am
2 stops21h 02m
Guayaquil Jose Joaquin de Olmedo
Mon 10/26
4:19 pm-10:51 am
1 stop17h 32m
$634
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Thu 11/19
12:05 pm-11:35 pm
2 stops35h 30m
Guayaquil Jose Joaquin de Olmedo
Sun 11/29
6:55 pm-9:59 am
1 stop15h 04m
$643
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Thu 10/22
8:00 am-3:24 pm
1 stop8h 24m
Guayaquil Jose Joaquin de Olmedo
Fri 10/23
1:30 pm-11:59 pm
1 stop9h 29m
$695
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Thu 10/22
8:00 am-3:24 pm
1 stop8h 24m
Guayaquil Jose Joaquin de Olmedo
Sun 10/25
1:30 pm-11:59 pm
1 stop9h 29m
$746
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 10/24
8:00 am-3:24 pm
1 stop8h 24m
Guayaquil Jose Joaquin de Olmedo
Sun 10/25
1:30 pm-11:59 pm
1 stop9h 29m
$788
Cheapest one-way
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 10/18
7:07 pm-1:29 pm
1 stop19h 22m
$247
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 12/20
7:03 pm-2:30 pm
2 stops19h 27m
$435
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 27, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.1
Boarding
7.5
Entertainment
6.8
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Overall
7.1
Boarding
7.5
Entertainment
6.8
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 27, 2026.
Cleveland and Guayaquil flights
Browse other Cleveland and Guayaquil flight options. Last updated on August 27, 2026.
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Cleveland to Guayaquil
Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$746 | FlexibilityNo cancel fee | On-time71% |