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Guayaquil

$157+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
May 10 — May 171
Sun 5/10
Sun 5/17
1 adult, Economy
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Cheap flight deals from Cleveland to Guayaquil

Cheapest flights from Cleveland to Guayaquil
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:45 am
CLE
-
GYE
1 stop16h 19m
Multiple Airlines
Sun 5/3111:59 pm
GYE
-
CLE
2 stops31h 54m
Multiple Airlines
Deal found 4/9$437
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:55 pm
CLE
-
GYE
2 stops27h 09m
Multiple Airlines
Mon 5/46:45 pm
GYE
-
CLE
1 stop27h 15m
Multiple Airlines
Deal found 4/7$476
This Orbitz deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:01 am
CLE
-
GYE
2 stops26h 57m
JetBlue
Mon 5/43:51 pm
GYE
-
CLE
2 stops27h 10m
JetBlue
Deal found 4/7$617
This LATAM Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2311:46 am
CLE
-
GYE
1 stop20h 14m
LATAM Airlines
Mon 8/174:05 pm
GYE
-
CLE
1 stop18h 21m
LATAM Airlines
Deal found 4/7$654
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:14 pm
CLE
-
GYE
1 stop14h 46m
Delta
Mon 8/174:05 pm
GYE
-
CLE
2 stops22h 05m
Delta
Deal found 4/7$661
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:07 pm
CLE
-
GYE
1 stop19h 27m
American Airlines
Sun 8/26:00 am
GYE
-
CLE
2 stops16h 41m
American Airlines
Deal found 4/9$681
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:38 pm
CLE
-
GYE
2 stops18h 53m
American Airlines
Sun 5/316:00 am
GYE
-
CLE
2 stops16h 39m
American Airlines
Deal found 4/9$691
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:07 pm
CLE
-
GYE
1 stop19h 27m
American Airlines
Mon 8/178:00 am
GYE
-
CLE
1 stop14h 50m
American Airlines
Deal found 4/6$727

Find flight deals from Cleveland to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$437
(Kiwi.com)

One-way from

$157
(Kiwi.com)
Provider with most accurate pricing for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Cleveland Hopkins Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Cleveland Hopkins Intl to Guayaquil Jose Joaquin de Olmedo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Sun 5/24

7:45 am-11:04 pm

1 stop16h 19m

Guayaquil Jose Joaquin de Olmedo

Sun 5/31

11:59 pm-8:53 am

2 stops31h 54m

$437

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 4/30

9:01 am-10:58 am

2 stops26h 57m

Guayaquil Jose Joaquin de Olmedo

Mon 5/4

3:51 pm-8:01 pm

2 stops27h 10m

$617

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 7/23

11:46 am-7:00 am

1 stop20h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

4:05 pm-11:26 am

1 stop18h 21m

$654
Quickest round-trip

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 7/23

7:07 pm-1:34 pm

1 stop19h 27m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

8:00 am-11:50 pm

1 stop14h 50m

$727

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Mon 4/20

7:15 pm-5:31 pm

2 stops23h 16m

Guayaquil Jose Joaquin de Olmedo

Fri 4/24

8:28 am-10:14 am

2 stops24h 46m

$1,068
Cheapest one-way
Quickest one-way

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Sat 5/16

7:55 am-8:55 am

2 stops26h 00m

$157

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 4/30

8:55 pm-11:04 pm

2 stops27h 09m

$175

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/9

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cleveland to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 10, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,564 reviews

Comfort

7.2

Entertainment

6.8

Crew

7.9

Food

6.4

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,564 reviews
American Airlines
7.1
Good
11,564 reviews

Comfort

7.2

Entertainment

6.8

Crew

7.9

Food

6.4

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cleveland to Guayaquil?

    For as low as $727, JetBlue can have you in Guayaquil from Cleveland in 19h 27m. The distance between Cleveland and Guayaquil is about 3011 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Cleveland to Guayaquil round-trip?

    According to our current data, American Airlines ($540), offers the cheapest pricing from Cleveland to Guayaquil.

  • Can I find deals for flights from Cleveland to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cleveland to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Guayaquil.

  • Can I find deals for business class flights from Cleveland to Guayaquil?

    Yes. Cheapflights offers flight deals from Cleveland to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Cleveland to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Cleveland to Guayaquil

Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$540Average$684FlexibilityNo cancel feeOn-time71%

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