$175+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
May 17 — May 241
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:15 am
CLE
- GYE
1 stop15h 49m
Multiple Airlines
Sun 4/2611:59 pm
GYE
- CLE
2 stops30h 40m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/127:45 am
CLE
- GYE
2 stops26h 10m
Multiple Airlines
Sun 7/2611:59 pm
GYE
- CLE
1 stop20h 58m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$528
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:28 pm
CLE
- GYE
2 stops31h 36m
Multiple Airlines
Sun 4/2611:59 pm
GYE
- CLE
1 stop12h 59m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$659
This Cheapflightsfares deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:00 am
CLE
- GYE
1 stop8h 20m
JetBlue
Mon 8/171:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 4/15![JetBlue logo]()
$738
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:07 pm
CLE
- GYE
1 stop19h 27m
American Airlines
Mon 8/176:00 am
GYE
- CLE
1 stop16h 55m
American Airlines
Deal found 4/14![American Airlines logo]()
$747
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:41 pm
CLE
- GYE
2 stops17h 53m
American Airlines
Sun 7/262:37 pm
GYE
- CLE
2 stops19h 35m
American Airlines
Deal found 4/12![American Airlines logo]()
$761
This Expedia deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:55 pm
CLE
- GYE
2 stops18h 26m
JetBlue
Tue 1/55:00 pm
GYE
- CLE
1 stop30h 59m
JetBlue
Deal found 4/13![JetBlue logo]()
$1,055
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:00 am
CLE
- GYE
1 stop8h 20m
JetBlue
Mon 8/171:25 pm
GYE
- CLE
1 stop9h 34m
JetBlue
Deal found 4/15![JetBlue logo]()
$738
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:07 pm
CLE
- GYE
1 stop19h 27m
American Airlines
Mon 8/176:00 am
GYE
- CLE
1 stop16h 55m
American Airlines
Deal found 4/12![American Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:15 pm
CLE
- GYE
2 stops29h 21m
United Airlines
Mon 5/42:43 pm
GYE
- CLE
2 stops29h 05m
United Airlines
Deal found 4/15![United Airlines logo]()
$1,088
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated April 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:28 pm
CLE
- GYE
2 stops31h 36m
Multiple Airlines
Sun 4/2611:59 pm
GYE
- CLE
1 stop12h 59m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:15 am
CLE
- GYE
1 stop15h 49m
Multiple Airlines
Sun 4/2611:59 pm
GYE
- CLE
2 stops30h 40m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:16 pm
CLE
- GYE
2 stops12h 22m
United Airlines
Sun 4/268:28 am
GYE
- CLE
2 stops25h 57m
United Airlines
Deal found 4/13![United Airlines logo]()
$1,204
This LATAM Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:17 pm
CLE
- GYE
1 stop15h 38m
LATAM Airlines
Fri 4/244:00 pm
GYE
- CLE
1 stop18h 55m
LATAM Airlines
Deal found 4/13![LATAM Airlines logo]()
$1,156
This Avianca deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:55 pm
CLE
- GYE
2 stops19h 40m
Avianca
Fri 4/246:50 pm
GYE
- CLE
2 stops14h 02m
Avianca
Deal found 4/12![Avianca logo]()
$1,170
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:15 pm
CLE
- GYE
2 stops29h 21m
United Airlines
Mon 5/42:43 pm
GYE
- CLE
2 stops29h 05m
United Airlines
Deal found 4/15![United Airlines logo]()
$1,088
This Faresmojo deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:03 pm
CLE
- GYE
1 stop19h 28m
JetBlue
Sun 5/316:00 am
GYE
- CLE
1 stop11h 33m
JetBlue
Deal found 4/12![JetBlue logo]()
$1,147
This BusinessClass deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:19 pm
CLE
- GYE
2 stops27h 10m
Multiple Airlines
Sun 5/312:43 pm
GYE
- CLE
2 stops18h 25m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$1,155
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:24 pm
CLE
- GYE
2 stops28h 40m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:45 am
CLE
- GYE
1 stop16h 19m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:47 pm
CLE
- GYE
3 stops28h 14m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:24 pm
CLE
- GYE
3 stops38h 31m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$190
This oojo deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:03 pm
CLE
- GYE
2 stops14h 52m
Avianca
Deal found 4/16![Avianca logo]()
$328
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $528 (Kiwi.com) |
One-way from | $175 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Thu 7/23
8:00 am-3:20 pm
1 stop8h 20m
Guayaquil Jose Joaquin de Olmedo
Mon 8/17
1:25 pm-11:59 pm
1 stop9h 34m
$738
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Thu 7/23
7:07 pm-1:34 pm
1 stop19h 27m
Guayaquil Jose Joaquin de Olmedo
Mon 8/17
6:00 am-11:55 pm
1 stop16h 55m
$747
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Fri 5/1
7:15 pm-11:36 pm
2 stops29h 21m
Guayaquil Jose Joaquin de Olmedo
Mon 5/4
2:43 pm-8:48 pm
2 stops29h 05m
$1,088
Cheapest one-way
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Wed 5/20
7:24 pm-11:04 pm
2 stops28h 40m
$175
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sun 5/17
8:47 pm-12:01 am
3 stops28h 14m
$188
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 5/16
7:24 pm-8:55 am
3 stops38h 31m
$190
Quickest one-way
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 5/16
7:03 pm-8:55 am
2 stops14h 52m
$328
ClevelandGuayaquil
CLE - GYE
CLEGYE
Cleveland Hopkins Intl
Sat 5/16
6:55 am-10:58 am
1 stop29h 03m
$383
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 17, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Boarding
7.5
Comfort
7.2
Entertainment
6.9
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Crew
7.9
Food
6.4
Boarding
7.5
Comfort
7.2
Entertainment
6.9
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
Cleveland and Guayaquil flights
Browse other Cleveland and Guayaquil flight options. Last updated on April 17, 2026.
Other flights from Cleveland
Browse through other flights departing from Cleveland. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Cleveland to Guayaquil
Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$540 | Average$684 | FlexibilityNo cancel fee | On-time71% |