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Guayaquil

$181+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
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Cheap flight deals from Cleveland to Guayaquil

Cheapest flights from Cleveland to Guayaquil
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am
CLE
-
GYE
2 stops17h 45m
American Airlines
Sun 10/112:29 pm
GYE
-
CLE
2 stops18h 06m
American Airlines
Deal found 7/29$426
This Cheapflightsfares deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 am
CLE
-
GYE
1 stop9h 14m
JetBlue
Tue 9/2212:30 pm
GYE
-
CLE
1 stop10h 02m
JetBlue
Deal found 7/25$429
This Cheapflightsfares deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:00 am
CLE
-
GYE
1 stop9h 14m
JetBlue
Mon 9/2812:30 pm
GYE
-
CLE
1 stop10h 02m
JetBlue
Deal found 7/27$460
This Orbitz deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 am
CLE
-
GYE
1 stop9h 14m
Multiple Airlines
Tue 9/229:05 am
GYE
-
CLE
2 stops24h 10m
Multiple Airlines
Deal found 7/25$481
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:50 am
CLE
-
GYE
1 stop8h 32m
JetBlue
Sat 9/51:27 pm
GYE
-
CLE
1 stop9h 27m
JetBlue
Deal found 7/26$490
This Cheapflightsfares deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:50 am
CLE
-
GYE
1 stop8h 32m
JetBlue
Mon 9/71:27 pm
GYE
-
CLE
1 stop9h 28m
JetBlue
Deal found 7/28$512
This Cheapflightsfares deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 am
CLE
-
GYE
1 stop9h 14m
JetBlue
Sun 9/2712:30 pm
GYE
-
CLE
1 stop10h 02m
JetBlue
Deal found 7/28$514
This LATAM Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:11 am
CLE
-
GYE
2 stops22h 27m
Multiple Airlines
Thu 9/174:15 pm
GYE
-
CLE
1 stop29h 17m
Multiple Airlines
Deal found 7/27$525
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
CLE
-
GYE
2 stops17h 10m
American Airlines
Sun 9/276:00 am
GYE
-
CLE
2 stops16h 42m
American Airlines
Deal found 7/29$563

Find flight deals from Cleveland to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$426
(American Airlines)

One-way from

$181
(Kiwi.com)
Provider with most accurate pricing for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Cleveland Hopkins Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Cleveland Hopkins Intl to Guayaquil Jose Joaquin de Olmedo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 10/8

6:00 am-10:45 pm

2 stops17h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 10/11

2:29 pm-9:35 am

2 stops18h 06m

$426
Quickest round-trip

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Fri 9/18

7:00 am-3:14 pm

1 stop9h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 9/28

12:30 pm-11:32 pm

1 stop10h 02m

$460

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 9/10

11:11 am-8:38 am

2 stops22h 27m

Guayaquil Jose Joaquin de Olmedo

Thu 9/17

4:15 pm-10:32 pm

1 stop29h 17m

$525

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 9/24

6:00 am-10:10 pm

2 stops17h 10m

Guayaquil Jose Joaquin de Olmedo

Sun 9/27

6:00 am-11:42 pm

2 stops16h 42m

$563

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Sun 11/1

8:00 am-4:22 pm

1 stop8h 22m

Guayaquil Jose Joaquin de Olmedo

Sat 11/7

8:00 pm-12:48 am

2 stops28h 48m

$659

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Sun 9/13

7:49 pm-5:35 pm

2 stops22h 46m

Guayaquil Jose Joaquin de Olmedo

Wed 9/16

3:30 am-9:45 am

2 stops29h 15m

$778

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Thu 10/8

7:00 pm-11:30 pm

2 stops29h 30m

Guayaquil Jose Joaquin de Olmedo

Sat 10/10

3:30 am-11:02 am

3 stops30h 32m

$850

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Wed 12/16

11:14 am-7:43 am

2 stops20h 29m

Guayaquil Jose Joaquin de Olmedo

Sun 1/3

7:30 pm-1:22 pm

2 stops17h 52m

$982

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Tue 12/15

6:17 am-11:06 pm

2 stops16h 49m

Guayaquil Jose Joaquin de Olmedo

Sun 1/3

6:04 am-11:59 pm

1 stop17h 55m

$1,142

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Wed 12/16

5:09 pm-2:27 pm

1 stop21h 18m

Guayaquil Jose Joaquin de Olmedo

Sun 1/3

3:30 pm-10:39 am

2 stops19h 09m

$1,154

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 14 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cleveland to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cleveland to Guayaquil?

    For as low as $460, American Airlines can have you in Guayaquil from Cleveland in 9h 14m. The distance between Cleveland and Guayaquil is about 3011 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Cleveland to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cleveland to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Guayaquil.

  • Can I find deals for business class flights from Cleveland to Guayaquil?

    Yes. Cheapflights offers flight deals from Cleveland to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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