$212+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Cleveland to Guayaquil with Cheapflights
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Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:47 pm -
2 stops18h 44m
Mon 11/166:00 am -
1 stop16h 55m
Deal found 8/5![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:05 am -
2 stops17h 30m
Mon 11/93:31 pm -
2 stops18h 01m
Deal found 8/5![American Airlines logo]()
$488
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 am -
1 stop8h 22m
Sat 11/72:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$544
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:46 am -
2 stops17h 53m
Sun 10/116:00 am -
1 stop11h 37m
Deal found 8/9![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop8h 31m
Mon 11/93:31 pm -
2 stops18h 01m
Deal found 8/5![American Airlines logo]()
$575
This Cheapflightsfares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am -
1 stop9h 14m
Fri 10/91:30 pm -
1 stop9h 29m
Deal found 8/9![JetBlue logo]()
$589
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:00 am -
1 stop8h 22m
Sat 11/72:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$594
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:00 am -
1 stop8h 22m
Tue 10/201:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$544
This Priceline deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:46 pm -
2 stops28h 44m
Fri 10/91:30 pm -
1 stop9h 29m
Deal found 8/9![Multiple Airlines logo]()
$712
This oojo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:49 pm -
2 stops19h 46m
Thu 9/176:50 pm -
2 stops37h 56m
Deal found 8/7![Avianca logo]()
$728
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:38 pm -
2 stops27h 01m
Sat 9/126:00 am -
2 stops28h 28m
Deal found 8/7![American Airlines logo]()
$751
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop8h 22m
Wed 11/112:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$594
This Orbitz deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:00 pm -
2 stops29h 30m
Fri 4/303:45 pm -
2 stops21h 47m
Deal found 8/9![Multiple Airlines logo]()
$719
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:00 am -
1 stop8h 22m
Tue 11/172:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$687
This Cheapflightsfares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:00 am -
1 stop9h 14m
Fri 4/301:35 pm -
1 stop9h 24m
Deal found 8/9![JetBlue logo]()
$690
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:38 pm -
2 stops27h 01m
Sat 9/126:00 am -
2 stops28h 28m
Deal found 8/7![American Airlines logo]()
$751
This Expedia deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop9h 14m
Thu 9/179:00 am -
2 stops14h 39m
Deal found 8/5![Multiple Airlines logo]()
$622
This oojo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:49 pm -
2 stops19h 46m
Thu 9/176:50 pm -
2 stops37h 56m
Deal found 8/7![Avianca logo]()
$728
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop9h 14m
Thu 9/1712:30 pm -
1 stop10h 02m
Deal found 8/5![JetBlue logo]()
$732
This Cheapflightsfares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:00 am -
1 stop9h 14m
Fri 4/301:35 pm -
1 stop9h 24m
Deal found 8/9![JetBlue logo]()
$690
This Orbitz deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:00 pm -
2 stops29h 30m
Fri 4/303:45 pm -
2 stops21h 47m
Deal found 8/9![Multiple Airlines logo]()
$719
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:45 pm -
2 stops32h 52m
Deal found 8/7![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm -
3 stops42h 19m
Deal found 8/5![Multiple Airlines logo]()
$266
This Cheapflightsfares deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am -
1 stop9h 14m
Deal found 8/6![JetBlue logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:19 am -
1 stop16h 51m
Deal found 8/7![American Airlines logo]()
$320
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:50 am -
1 stop8h 32m
Deal found 8/5![JetBlue logo]()
$345
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $479 (American Airlines) |
One-way from | $212 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 10/17
8:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Tue 10/20
1:30 pm-11:59 pm
1 stop9h 29m
$544
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Wed 10/28
8:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Wed 11/11
2:30 pm-11:59 pm
1 stop9h 29m
$594
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 11/9
8:00 am-4:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Tue 11/17
2:30 pm-11:59 pm
1 stop9h 29m
$687
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 9/27
7:00 am-3:14 pm
1 stop9h 14m
Guayaquil Jose Joaquin de Olmedo
Fri 4/30
1:35 pm-11:59 pm
1 stop9h 24m
$690
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Fri 10/2
7:46 pm-11:30 pm
2 stops28h 44m
Guayaquil Jose Joaquin de Olmedo
Fri 10/9
1:30 pm-11:59 pm
1 stop9h 29m
$712
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 9/27
7:00 pm-11:30 pm
2 stops29h 30m
Guayaquil Jose Joaquin de Olmedo
Fri 4/30
3:45 pm-2:32 pm
2 stops21h 47m
$719
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Thu 9/10
7:49 pm-2:35 pm
2 stops19h 46m
Guayaquil Jose Joaquin de Olmedo
Thu 9/17
6:50 pm-9:46 am
2 stops37h 56m
$728
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 8/30
7:38 pm-9:39 pm
2 stops27h 01m
Guayaquil Jose Joaquin de Olmedo
Sat 9/12
6:00 am-11:28 am
2 stops28h 28m
$751
Cheapest one-way
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Wed 9/9
7:59 pm-11:37 pm
3 stops28h 38m
$244
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Wed 9/9
7:00 am-3:14 pm
1 stop9h 14m
$295
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Entertainment
6.8
Comfort
7.2
Food
6.4
Overall
7.1
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Boarding
7.5
Entertainment
6.8
Comfort
7.2
Food
6.4
Overall
7.1
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Cleveland and Guayaquil flights
Browse other Cleveland and Guayaquil flight options. Last updated on August 10, 2026.
Other flights from Cleveland
Browse through other flights departing from Cleveland. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Cleveland to Guayaquil
Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$746 | FlexibilityNo cancel fee | On-time71% |