$266+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Sep 5 — Sep 121
Round-trip
1 adult, Economy
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Find cheap flights from Cleveland to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cleveland to Guayaquil
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One-way
Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:09 am -
1 stop17h 26m
Sun 10/116:00 am -
1 stop16h 46m
Deal found 8/4![American Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:47 pm -
2 stops18h 44m
Mon 11/166:00 am -
1 stop16h 55m
Deal found 8/5![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:05 am -
2 stops17h 30m
Mon 11/93:31 pm -
2 stops18h 01m
Deal found 8/5![American Airlines logo]()
$488
This Expedia deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am -
1 stop9h 14m
Wed 9/234:15 pm -
1 stop17h 32m
Deal found 8/1![Multiple Airlines logo]()
$530
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 am -
1 stop8h 22m
Mon 11/92:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$544
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop8h 31m
Mon 11/93:31 pm -
2 stops18h 01m
Deal found 8/5![American Airlines logo]()
$575
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:46 am -
2 stops17h 49m
Sun 10/112:29 pm -
2 stops18h 07m
Deal found 8/4![American Airlines logo]()
$436
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:00 am -
1 stop8h 22m
Tue 10/201:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$544
This Avianca deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:49 pm -
2 stops22h 46m
Wed 9/163:30 am -
2 stops29h 15m
Deal found 8/1![Avianca logo]()
$778
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:38 pm -
2 stops27h 01m
Sat 9/126:00 am -
2 stops28h 28m
Deal found 8/1![American Airlines logo]()
$581
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:00 am -
1 stop8h 22m
Wed 11/112:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$594
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am -
1 stop9h 14m
Wed 9/2312:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$594
This JetBlue deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop8h 22m
Wed 11/112:30 pm -
1 stop9h 29m
Deal found 8/5![JetBlue logo]()
$594
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:46 pm -
2 stops19h 49m
Mon 10/193:30 am -
2 stops29h 11m
Deal found 8/3![Avianca logo]()
$778
This JetBlue deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop9h 14m
Thu 9/1712:30 pm -
1 stop10h 02m
Deal found 8/1![JetBlue logo]()
$788
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop9h 14m
Mon 9/2112:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$788
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 6, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated August 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:38 pm -
2 stops27h 01m
Sat 9/126:00 am -
2 stops28h 28m
Deal found 8/1![American Airlines logo]()
$581
This Expedia deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:49 pm -
2 stops28h 41m
Thu 9/179:00 am -
2 stops14h 39m
Deal found 8/5![Multiple Airlines logo]()
$714
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:57 pm -
1 stop11h 23m
Sun 9/203:30 am -
2 stops13h 32m
Deal found 8/3![Multiple Airlines logo]()
$583
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop9h 14m
Fri 9/2512:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$645
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop9h 14m
Wed 9/2312:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$695
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am -
1 stop9h 14m
Fri 9/2512:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$544
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am -
1 stop9h 14m
Wed 9/2312:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$594
This JetBlue deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am -
1 stop9h 14m
Sun 9/2012:30 pm -
1 stop10h 02m
Deal found 8/3![JetBlue logo]()
$687
This LATAM Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:05 am -
2 stops25h 13m
Wed 9/234:15 pm -
1 stop17h 32m
Deal found 8/3![LATAM Airlines logo]()
$719
This Expedia deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am -
1 stop9h 14m
Wed 9/234:15 pm -
1 stop17h 32m
Deal found 8/1![Multiple Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:30 am -
2 stops17h 40m
Wed 9/236:00 am -
1 stop16h 46m
Deal found 8/1![American Airlines logo]()
$622
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm -
3 stops42h 19m
Deal found 8/5![Multiple Airlines logo]()
$266
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:50 am -
1 stop8h 32m
Deal found 8/5![JetBlue logo]()
$345
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 6, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $432 (American Airlines) |
One-way from | $266 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Thu 10/8
5:46 am-10:35 pm
2 stops17h 49m
Guayaquil Jose Joaquin de Olmedo
Sun 10/11
2:29 pm-9:36 am
2 stops18h 07m
$436
Quickest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 10/17
8:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Tue 10/20
1:30 pm-11:59 pm
1 stop9h 29m
$544
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 8/30
7:38 pm-9:39 pm
2 stops27h 01m
Guayaquil Jose Joaquin de Olmedo
Sat 9/12
6:00 am-11:28 am
2 stops28h 28m
$581
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Tue 10/27
8:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Wed 11/11
2:30 pm-11:59 pm
1 stop9h 29m
$594
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 9/14
7:00 am-3:14 pm
1 stop9h 14m
Guayaquil Jose Joaquin de Olmedo
Wed 9/23
12:30 pm-11:32 pm
1 stop10h 02m
$594
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Wed 10/28
8:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Wed 11/11
2:30 pm-11:59 pm
1 stop9h 29m
$594
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 9/13
7:49 pm-5:35 pm
2 stops22h 46m
Guayaquil Jose Joaquin de Olmedo
Wed 9/16
3:30 am-9:45 am
2 stops29h 15m
$778
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 10/17
7:46 pm-2:35 pm
2 stops19h 49m
Guayaquil Jose Joaquin de Olmedo
Mon 10/19
3:30 am-9:41 am
2 stops29h 11m
$778
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 9/13
7:00 am-3:14 pm
1 stop9h 14m
Guayaquil Jose Joaquin de Olmedo
Thu 9/17
12:30 pm-11:32 pm
1 stop10h 02m
$788
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 9/13
7:00 am-3:14 pm
1 stop9h 14m
Guayaquil Jose Joaquin de Olmedo
Mon 9/21
12:30 pm-11:32 pm
1 stop10h 02m
$788
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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