$267+ Cheap flights from Cleveland (CLE) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — GYE
Nov 4 — Nov 111
Round-trip
1 adult, Economy
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Find cheap flights from Cleveland to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cleveland to Guayaquil
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Cheapest flights from Cleveland to GuayaquilExplore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
Explore the most affordable flight options available from Cleveland to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:07 pm -
1 stop10h 13m
Fri 10/910:05 am -
2 stops21h 42m
Deal found 10/1![Multiple Airlines logo]()
$807
This JetBlue deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 24m
Fri 10/161:30 pm -
1 stop9h 29m
Deal found 9/30![JetBlue logo]()
$828
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:00 am -
2 stops18h 52m
Thu 1/73:48 pm -
1 stop26h 06m
Deal found 10/4![American Airlines logo]()
$906
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:00 am -
1 stop15h 26m
Mon 1/43:30 pm -
1 stop26h 29m
Deal found 10/1![American Airlines logo]()
$913
This Cheapflightsfares deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
1 stop9h 24m
Fri 10/91:30 pm -
1 stop9h 29m
Deal found 10/1![JetBlue logo]()
$919
This BusinessClass deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:29 pm -
2 stops21h 06m
Mon 1/43:30 pm -
1 stop26h 29m
Deal found 10/1![GOL logo]()
$940
This KAYAK deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:30 pm -
2 stops28h 22m
Thu 1/73:48 pm -
2 stops29h 44m
Deal found 10/4![GOL logo]()
$956
This Cheapflightsfares deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:00 am -
1 stop8h 29m
Thu 1/72:34 pm -
1 stop9h 25m
Deal found 10/3![JetBlue logo]()
$979
Best flights from Cleveland to GuayaquilDiscover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
Discover carefully curated flight deals from Cleveland to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/175:40 am -
1 stop9h 08m
Sun 1/316:00 am -
1 stop17h 59m
Deal found 9/30![American Airlines logo]()
$544
This BusinessClass deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:29 pm -
2 stops21h 06m
Mon 1/43:30 pm -
1 stop26h 29m
Deal found 10/1![GOL logo]()
$940
This Cheapflightsfares deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:00 am -
1 stop8h 29m
Thu 1/72:34 pm -
1 stop9h 25m
Deal found 10/3![JetBlue logo]()
$979
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:08 am -
2 stops18h 44m
Thu 1/73:48 pm -
1 stop26h 06m
Deal found 10/3![American Airlines logo]()
$906
This KAYAK deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:30 pm -
2 stops28h 22m
Thu 1/73:48 pm -
2 stops29h 44m
Deal found 10/4![GOL logo]()
$956
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:00 am -
1 stop15h 26m
Mon 1/43:30 pm -
1 stop26h 29m
Deal found 10/1![American Airlines logo]()
$913
This BusinessClass deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
2 stops17h 55m
Fri 1/83:48 pm -
2 stops20h 05m
Deal found 10/2![GOL logo]()
$1,289
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:49 pm -
1 stop19h 41m
Fri 1/86:00 am -
1 stop11h 54m
Deal found 10/2![American Airlines logo]()
$1,256
Last-minute flights from Cleveland to GuayaquilDiscover last-minute flight deals from Cleveland to Guayaquil. Data last updated October 5, 2026 and is based on user searches.
Discover last-minute flight deals from Cleveland to Guayaquil. Data last updated October 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:07 pm -
1 stop10h 13m
Fri 10/910:05 am -
2 stops21h 42m
Deal found 10/1![Multiple Airlines logo]()
$807
This Cheapflightsfares deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
1 stop9h 24m
Fri 10/91:30 pm -
1 stop9h 29m
Deal found 10/1![JetBlue logo]()
$919
This JetBlue deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 24m
Fri 10/161:30 pm -
1 stop9h 29m
Deal found 9/30![JetBlue logo]()
$828
This Avianca deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:45 pm -
2 stops28h 45m
Fri 10/1610:05 am -
2 stops22h 36m
Deal found 9/30![Avianca logo]()
$1,063
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:00 am -
1 stop15h 26m
Mon 1/43:30 pm -
1 stop26h 29m
Deal found 10/1![American Airlines logo]()
$913
This BusinessClass deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:29 pm -
2 stops21h 06m
Mon 1/43:30 pm -
1 stop26h 29m
Deal found 10/1![GOL logo]()
$940
One-way flights from Cleveland to GuayaquilSearch for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
Search for one-way flight options from Cleveland to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
This LATAM Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:23 pm -
1 stop19h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![LATAM Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:46 pm -
3 stops32h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:41 pm -
2 stops20h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![American Airlines logo]()
$283
This Cheapflightsfares deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:00 am -
1 stop8h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![JetBlue logo]()
$290
This BusinessClass deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:51 pm -
2 stops19h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![GOL logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/129:59 pm -
2 stops26h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$355
This Cheapflightsfares deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop8h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![JetBlue logo]()
$415
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:21 pm -
3 stops23h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$422
Find flight deals from Cleveland to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 5, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $544 (American Airlines) |
One-way from | $267 (LATAM Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cleveland to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
Use the filters below to find and compare flights from Cleveland to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 11/21
12:23 pm-8:02 am
1 stop19h 39m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$267
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 11/21
12:23 pm-8:02 am
1 stop19h 39m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$267
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sat 11/21
5:41 pm-2:35 pm
2 stops20h 54m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$283
Quickest round-trip
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Thu 10/22
8:00 am-3:24 pm
1 stop8h 24m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$290
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Wed 11/4
6:51 pm-2:34 pm
2 stops19h 43m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$295
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 1/17
5:40 am-2:48 pm
1 stop9h 08m
Guayaquil Jose Joaquin de Olmedo
Sun 1/31
6:00 am-11:59 pm
1 stop17h 59m
$544
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 12/14
5:08 am-11:52 pm
2 stops18h 44m
Guayaquil Jose Joaquin de Olmedo
Thu 1/7
3:48 pm-5:54 pm
1 stop26h 06m
$906
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 11/29
8:00 am-11:26 pm
1 stop15h 26m
Guayaquil Jose Joaquin de Olmedo
Mon 1/4
3:30 pm-5:59 pm
1 stop26h 29m
$913
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Sun 11/29
5:29 pm-2:35 pm
2 stops21h 06m
Guayaquil Jose Joaquin de Olmedo
Mon 1/4
3:30 pm-5:59 pm
1 stop26h 29m
$940
ClevelandGuayaquil
CLE Cleveland Hopkins Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLEGYE
Cleveland Hopkins Intl
Mon 12/14
7:30 pm-11:52 pm
2 stops28h 22m
Guayaquil Jose Joaquin de Olmedo
Thu 1/7
3:48 pm-9:32 pm
2 stops29h 44m
$956
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Cleveland-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Cleveland-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Cleveland-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cleveland-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cleveland to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cleveland with our price prediction graph.
CLE-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated October 5, 2026.
Read through reviews of airlines operating flights from Cleveland to Guayaquil, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Cleveland to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
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Cleveland and Guayaquil flights
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Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Cleveland to Guayaquil
Discover the top airline that operate flights from Cleveland to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$746 | FlexibilityNo cancel fee | On-time71% |