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$350+ Cheap flights from Santa Cruz de la Sierra (VVI) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — GUA
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Santa Cruz de la Sierra to Guatemala City

Best flights from Santa Cruz de la Sierra to Guatemala City
Discover carefully curated flight deals from Santa Cruz de la Sierra to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 21, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/121:15 amVVI - GUA
1 stop10h 19mCopa Airlines
Sun 2/226:24 amGUA - VVI
2 stops14h 26mCopa Airlines
Deal found 12/19$787
This Copa Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:15 amVVI - GUA
1 stop12h 35mCopa Airlines
Fri 5/87:10 amGUA - VVI
1 stop13h 28mCopa Airlines
Deal found 12/20$787
This Copa Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:15 amVVI - GUA
1 stop9h 34mCopa Airlines
Mon 5/46:24 amGUA - VVI
2 stops14h 14mCopa Airlines
Deal found 12/19$787
This Copa Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:47 amVVI - GUA
2 stops11h 54mCopa Airlines
Fri 5/156:24 amGUA - VVI
2 stops14h 14mCopa Airlines
Deal found 12/19$787
This Copa Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/161:15 amVVI - GUA
1 stop12h 21mCopa Airlines
Sun 2/226:24 amGUA - VVI
2 stops19h 20mCopa Airlines
Deal found 12/20$787
This Copa Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/121:15 amVVI - GUA
1 stop10h 19mCopa Airlines
Tue 2/246:24 amGUA - VVI
2 stops14h 26mCopa Airlines
Deal found 12/19$787

Find flight deals from Santa Cruz de la Sierra to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$658
(Avianca)

One-way from

$350
(Avianca)

Popular in

January

Cheapest in

September

Average price

$640
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Guatemala City La Aurora flights.
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From Santa Cruz de la Sierra Viru Viru Intl to Guatemala City La Aurora
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($118 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($50 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Guatemala City that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Guatemala City

Route

Depart

Return

Price

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/12

1:15 am-9:34 am

1 stop10h 19m

Guatemala City La Aurora

Sun 2/22

6:24 am-10:50 pm

2 stops14h 26m

$787

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/23

1:15 am-11:50 am

1 stop12h 35m

Guatemala City La Aurora

Fri 5/8

7:10 am-10:38 pm

1 stop13h 28m

$787

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/9

1:15 am-8:49 am

1 stop9h 34m

Guatemala City La Aurora

Mon 5/4

6:24 am-10:38 pm

2 stops14h 14m

$787

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

11:47 am-9:41 pm

2 stops11h 54m

Guatemala City La Aurora

Fri 5/15

6:24 am-10:38 pm

2 stops14h 14m

$787

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/16

1:15 am-11:36 am

1 stop12h 21m

Guatemala City La Aurora

Sun 2/22

6:24 am-3:44 am

2 stops19h 20m

$787

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/12

1:15 am-9:34 am

1 stop10h 19m

Guatemala City La Aurora

Tue 2/24

6:24 am-10:50 pm

2 stops14h 26m

$787

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Fri 1/23

3:40 am-1:00 pm

1 stop11h 20m

$350

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/1

3:40 am-1:00 pm

1 stop11h 20m

$350

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/1

1:14 am-9:40 pm

2 stops22h 26m

$451

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Wed 1/21

1:15 am-9:34 am

1 stop10h 19m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 18 results
1
2

Compare providers for flights from Santa Cruz de la Sierra to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to Guatemala City in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Guatemala City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Cruz de la Sierra-Guatemala City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Guatemala City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Guatemala City

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Guatemala City?

Currently, February is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Guatemala City (average of $431). Flying from Santa Cruz de la Sierra to Guatemala City in July is currently the most expensive (average of $760). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated December 21, 2025.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Guatemala City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,558 reviews

Boarding

7.8

Comfort

7.4

Crew

8.1

Food

6.8

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Maria,Dec 2025

MIA - PTY

The second flight to salta Argentina was terrible..the plain is old no entertainment no good food no nothing
Copa Airlines
7.6
Good
1,558 reviews
Copa Airlines
7.6
Good
1,558 reviews

Boarding

7.8

Comfort

7.4

Crew

8.1

Food

6.8

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Maria,Dec 2025

MIA - PTY

The second flight to salta Argentina was terrible..the plain is old no entertainment no good food no nothing
Avianca
6.6
Okay
2,487 reviews
Copa Airlines
7.6
Good
1,558 reviews

Boarding

7.8

Comfort

7.4

Crew

8.1

Food

6.8

Overall

7.6

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Maria,Dec 2025

MIA - PTY

The second flight to salta Argentina was terrible..the plain is old no entertainment no good food no nothing

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Guatemala City?

    A quick flight from Santa Cruz de la Sierra to Guatemala City can take about 10h 19m. Copa Airlines provides one of the quickest options available for as low as $787. There are 2904 mi between Santa Cruz de la Sierra and Guatemala City.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Guatemala City round-trip?

    According to our current data, Avianca ($537), and Copa Airlines ($741) offers the cheapest pricing from Santa Cruz de la Sierra to Guatemala City. Avianca is priced at 28% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Cruz de la Sierra to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Guatemala City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Guatemala City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Guatemala City?

    Currently, February is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Guatemala City (average of $431). Flying from Santa Cruz de la Sierra to Guatemala City in July is currently the most expensive (average of $760). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

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Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santa Cruz de la Sierra to Guatemala City

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$537Average$694FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$741Average$1,291FlexibilityNo cancel feeOn-time70%

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