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$310+ Cheap flights from Santa Cruz de la Sierra (VVI) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — GUA
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Santa Cruz de la Sierra to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$555
(Avianca)

One-way from

$310
(Priceline)

Popular in

January

Cheapest in

August

Average price

$660
From Santa Cruz de la Sierra Viru Viru Intl to Guatemala City La Aurora
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Guatemala City La Aurora
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Highest demand for flights based on searches. 15% potential increase in price ($144 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($52 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santa Cruz de la Sierra to Guatemala City

Cheapest flights from Santa Cruz de la Sierra to Guatemala City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/302:50 amVVI - GUA
1 stop16h 25mAvianca
Wed 10/159:40 amGUA - VVI
1 stop14h 10mAvianca
Deal found 9/14$555
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/311:40 amVVI - GUA
1 stop13h 31mCopa Airlines
Sun 11/234:21 amGUA - VVI
1 stop16h 25mCopa Airlines
Deal found 9/15$764
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:09 amVVI - GUA
2 stops22h 27mCopa Airlines
Tue 11/45:39 amGUA - VVI
2 stops15h 07mCopa Airlines
Deal found 9/15$772
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:09 amVVI - GUA
2 stops22h 29mCopa Airlines
Mon 11/245:39 amGUA - VVI
2 stops15h 07mCopa Airlines
Deal found 9/16$780
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/271:09 amVVI - GUA
1 stop10h 25mCopa Airlines
Wed 12/314:24 amGUA - VVI
1 stop16h 26mCopa Airlines
Deal found 9/15$781
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:09 amVVI - GUA
2 stops22h 29mCopa Airlines
Mon 1/194:24 amGUA - VVI
1 stop16h 26mCopa Airlines
Deal found 9/15$814
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/141:09 amVVI - GUA
2 stops22h 29mCopa Airlines
Tue 12/236:24 amGUA - VVI
2 stops14h 22mCopa Airlines
Deal found 9/15$831
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:40 amVVI - GUA
1 stop16h 00mAvianca
Fri 12/261:55 pmGUA - VVI
1 stop10h 40mAvianca
Deal found 9/14$871
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:25 amVVI - GUA
2 stops33h 35mMultiple Airlines
Fri 12/266:53 pmGUA - VVI
1 stop29h 42mMultiple Airlines
Deal found 9/14$884

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Guatemala City that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Guatemala City

Route

Depart

Return

Price

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/14

1:09 am-9:34 am

1 stop10h 25m

Guatemala City La Aurora

Tue 12/23

6:24 am-10:46 pm

2 stops14h 22m

$764

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/10

1:15 am-9:34 am

1 stop10h 19m

Guatemala City La Aurora

Wed 2/18

4:24 am-10:50 pm

1 stop16h 26m

$764

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/3

11:40 am-11:11 pm

1 stop13h 31m

Guatemala City La Aurora

Sun 11/23

4:21 am-10:46 pm

1 stop16h 25m

$764

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/9

1:09 am-8:56 am

1 stop9h 47m

Guatemala City La Aurora

Mon 1/19

2:26 am-10:50 pm

1 stop18h 24m

$764

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/12

1:15 am-9:34 am

1 stop10h 19m

Guatemala City La Aurora

Sun 2/22

6:24 am-3:44 am

2 stops19h 20m

$764

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/14

2:50 am-5:15 pm

1 stop16h 25m

$310

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Fri 11/14

3:40 am-1:00 pm

1 stop11h 20m

$310

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/23

11:59 am-9:36 pm

2 stops11h 37m

$414

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/2

11:44 am-9:40 pm

2 stops11h 56m

$414

Santa Cruz de la SierraGuatemala City

VVI - GUA

VVIGUA

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/14

1:09 am-9:36 pm

2 stops22h 27m

$422

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 13 results
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Best time to book a flight from Santa Cruz de la Sierra to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Guatemala City

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Guatemala City (average of $291). Flying from Santa Cruz de la Sierra to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Santa Cruz de la Sierra to Guatemala City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Guatemala City?

    A quick flight from Santa Cruz de la Sierra to Guatemala City can take about 10h 25m. Copa Airlines provides one of the quickest options available for as low as $764. There are 2904 mi between Santa Cruz de la Sierra and Guatemala City.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Guatemala City round-trip?

    According to our current data, Avianca ($554), and Copa Airlines ($642) offers the cheapest pricing from Santa Cruz de la Sierra to Guatemala City. Avianca is priced at 29% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Cruz de la Sierra to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Guatemala City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Guatemala City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Guatemala City (average of $291). Flying from Santa Cruz de la Sierra to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Guatemala City car rentals
Guatemala City La Aurora Airport car rentals

Top 2 airlines flying from Santa Cruz de la Sierra to Guatemala City

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$554Average$756FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$642Average$1,291FlexibilityNo cancel feeOn-time70%

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