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$168+ Cheap flights from New Orleans to Greenville (MSY - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — GSP
Jan 24 — Jan 311
Sat 1/24
Sat 1/31
1 adult, Economy
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Cheap flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:26 pmMSY - GSP
1 stop4h 04mDelta
Wed 1/285:40 amGSP - MSY
1 stop5h 28mDelta
Deal found 12/24$367
This American Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 amMSY - GSP
2 stops7h 50mAmerican Airlines
Wed 1/2810:23 amGSP - MSY
1 stop7h 21mAmerican Airlines
Deal found 12/24$372
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:15 amMSY - GSP
1 stop4h 43mDelta
Wed 1/285:40 amGSP - MSY
1 stop4h 10mDelta
Deal found 12/24$437
This Kiwi.com deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:55 pmMSY - GSP
1 stop18h 10mMultiple Airlines
Fri 1/28:58 pmGSP - MSY
2 stops21h 52mMultiple Airlines
Deal found 12/24$447
This Kiwi.com deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:55 pmMSY - GSP
1 stop18h 10mMultiple Airlines
Thu 12/252:06 pmGSP - MSY
1 stop9h 21mMultiple Airlines
Deal found 12/23$478
This Kiwi.com deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:55 pmMSY - GSP
1 stop18h 10mMultiple Airlines
Wed 12/244:40 pmGSP - MSY
1 stop8h 19mMultiple Airlines
Deal found 12/23$498
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:17 amMSY - GSP
1 stop4h 37mDelta
Fri 1/24:30 pmGSP - MSY
1 stop4h 52mDelta
Deal found 12/24$507
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:45 amMSY - GSP
1 stop7h 48mAmerican Airlines
Thu 12/258:00 amGSP - MSY
2 stops9h 37mAmerican Airlines
Deal found 12/23$547

Find flight deals from New Orleans to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from New Orleans (MSY) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 25, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$168
(Kiwi.com)

Popular in

September

Cheapest in

April

Average price

$471
Provider with most accurate pricing for New Orleans Louis Armstrong-Greenville flight deals.
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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Greenville flights.
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From New Orleans Louis Armstrong to Greenville
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High demand for flights, 4% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from New Orleans to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 25, 2025.
Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Fly from

New Orleans

Fly to

Greenville

Route

Depart

Return

Price

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 1/29

7:42 pm-8:58 am

1 stop12h 16m

Greenville

Mon 2/2

9:48 am-9:29 pm

1 stop12h 41m

$168

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 1/22

7:42 pm-8:58 am

1 stop12h 16m

Greenville

Thu 1/29

5:45 pm-9:29 pm

1 stop28h 44m

$191

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/13

7:52 am-6:26 pm

1 stop9h 34m

Greenville

Tue 1/20

7:00 am-6:13 pm

1 stop12h 13m

$239

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/20

1:27 pm-8:56 pm

1 stop6h 29m

Greenville

Tue 1/27

7:00 am-6:10 pm

1 stop12h 10m

$247

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 1/21

6:00 am-6:26 pm

1 stop11h 26m

Greenville

Wed 1/28

6:56 pm-11:56 pm

1 stop6h 00m

$268

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Fri 2/6

8:00 am-6:26 pm

1 stop9h 26m

Greenville

Mon 2/9

4:40 pm-10:59 pm

1 stop7h 19m

$300

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sun 3/1

8:00 am-3:35 pm

1 stop6h 35m

Greenville

Wed 3/4

10:05 am-6:40 pm

2 stops9h 35m

$337

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 1/29

8:15 am-5:35 pm

2 stops8h 20m

Greenville

Mon 2/2

11:15 am-4:55 pm

2 stops6h 40m

$348

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 1/13

7:00 am-3:35 pm

1 stop7h 35m

Greenville

Tue 1/20

11:50 am-7:45 pm

2 stops8h 55m

$351

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 12/30

3:10 pm-3:55 pm

1 stop23h 45m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Showing 1-10 of 11 results
1
2

Compare providers for flights from New Orleans to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Greenville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on New Orleans-Greenville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Greenville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on New Orleans-Greenville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

Currently, February is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $78). Flying from New Orleans to Greenville in December is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to GSP?

Find hourly flight availability from New Orleans to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 25, 2025.

It’s optimal to fly from New Orleans to Greenville in the morning. By choosing this option you can save up to 58% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated December 25, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Overall

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Overall

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,056 reviews
Delta
7.9
Good
8,011 reviews

Overall

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New Orleans to Greenville?

    American Airlines can get you from New Orleans to Greenville in just under 9h 34m. Your travel time can differ by up to . The distance between New Orleans and Greenville is about 578 mi.

  • What are the cheapest airlines flying from New Orleans to Greenville round-trip?

    According to our current data, Delta ($140), and American Airlines ($295) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 66% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from New Orleans to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $118. Southwest flights start at $118 while deals on American Airlines start at $148 one-way.

  • Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

    Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from New Orleans to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.

  • Can I find deals for business class flights from New Orleans to Greenville?

    Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New Orleans to Greenville?

    Currently, February is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $78). Flying from New Orleans to Greenville in December is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 2 airlines flying from New Orleans to Greenville

Discover the top 2 airlines that operate flights from New Orleans to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$252Average$419FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$295Average$399FlexibilityNo cancel feeOn-time71%

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