What are the cheapest airlines flying from New Orleans to Greenville round-trip?

According to our current data, Delta ($252), and American Airlines ($295) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 36% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Most accurate provider : When it comes to deals on New Orleans-Greenville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Greenville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Greenville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on New Orleans-Greenville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from New Orleans to Greenville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.

Can I find deals for business class flights from New Orleans to Greenville?

Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$113+ Flights from New Orleans to Greenville

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1. Tell us where you want to go

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Cheap flight deals from New Orleans to Greenville

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$210 (Kiwi.com)
One-way from	$113 (Kiwi.com)
Popular in	September
Cheapest in	April
Average price	$487

Provider with most accurate pricing for New Orleans Louis Armstrong-Greenville flight deals.

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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Greenville flights.

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From New Orleans Louis Armstrong to Greenville

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One-way flight from New Orleans Louis Armstrong to Greenville

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High demand for flights, 0% potential price rise

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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).

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Average for round-trip flights in November 2025

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Find flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

Thu 12/42:02 pmMSY - GSP

1 stop28h 21mMultiple Airlines

Sun 12/72:06 pmGSP - MSY

1 stop9h 21mMultiple Airlines

Deal found 11/24

$210

Mon 12/85:15 amMSY - GSP

1 stop13h 08mMultiple Airlines

Fri 12/128:03 pmGSP - MSY

2 stops26h 39mMultiple Airlines

Deal found 11/23

$222

Tue 12/306:55 pmMSY - GSP

1 stop18h 10mMultiple Airlines

Fri 1/28:58 pmGSP - MSY

1 stop12h 19mMultiple Airlines

Deal found 11/23

$254

Mon 12/296:40 amMSY - GSP

1 stop10h 55mMultiple Airlines

Fri 1/28:58 pmGSP - MSY

1 stop12h 19mMultiple Airlines

Deal found 11/22

$256

Thu 12/47:00 amMSY - GSP

2 stops25h 16mBreeze Airways

Sun 12/72:06 pmGSP - MSY

1 stop9h 21mBreeze Airways

Deal found 11/24

$261

Best flights from New Orleans to Greenville
Discover carefully curated flight deals from New Orleans to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 24, 2025.

Thu 12/42:02 pmMSY - GSP

1 stop28h 21mMultiple Airlines

Sun 12/72:06 pmGSP - MSY

1 stop9h 21mMultiple Airlines

Deal found 11/24

$210

Wed 3/49:30 amMSY - GSP

2 stops7h 10mSouthwest

Mon 3/96:25 amGSP - MSY

2 stops7h 15mSouthwest

Deal found 11/21

$329

Wed 4/812:15 pmMSY - GSP

1 stop8h 07mUnited Airlines

Sun 4/126:30 amGSP - MSY

1 stop7h 53mUnited Airlines

Deal found 11/22

$367

Mon 12/85:15 amMSY - GSP

1 stop13h 08mMultiple Airlines

Fri 12/128:03 pmGSP - MSY

2 stops26h 39mMultiple Airlines

Deal found 11/23

$222

Wed 3/47:27 pmMSY - GSP

1 stop19h 24mMultiple Airlines

Mon 3/96:43 pmGSP - MSY

1 stop27h 12mMultiple Airlines

Deal found 11/21

$255

Mon 12/296:40 amMSY - GSP

1 stop10h 55mMultiple Airlines

Fri 1/28:58 pmGSP - MSY

1 stop12h 19mMultiple Airlines

Deal found 11/22

$256

Tue 12/305:00 pmMSY - GSP

2 stops21h 55mMultiple Airlines

Fri 1/28:58 pmGSP - MSY

1 stop12h 19mMultiple Airlines

Deal found 11/23

$274

Thu 3/56:15 amMSY - GSP

1 stop8h 36mMultiple Airlines

Mon 3/96:43 pmGSP - MSY

2 stops17h 32mMultiple Airlines

Deal found 11/21

$303

Last-minute flights from New Orleans to Greenville
Discover last-minute flight deals from New Orleans to Greenville. Data last updated November 24, 2025 and is based on user searches.

Thu 12/42:02 pmMSY - GSP

1 stop28h 21mMultiple Airlines

Sun 12/72:06 pmGSP - MSY

1 stop9h 21mMultiple Airlines

Deal found 11/24

$210

Thu 12/47:00 amMSY - GSP

2 stops25h 16mBreeze Airways

Sun 12/72:06 pmGSP - MSY

1 stop9h 21mBreeze Airways

Deal found 11/24

$261

Mon 12/85:15 amMSY - GSP

1 stop13h 08mMultiple Airlines

Fri 12/128:03 pmGSP - MSY

2 stops26h 39mMultiple Airlines

Deal found 11/23

$222

Mon 12/296:40 amMSY - GSP

1 stop10h 55mMultiple Airlines

Fri 1/28:58 pmGSP - MSY

1 stop12h 19mMultiple Airlines

Deal found 11/22

$256

Tue 12/306:55 pmMSY - GSP

1 stop18h 10mMultiple Airlines

Fri 1/28:58 pmGSP - MSY

1 stop12h 19mMultiple Airlines

Deal found 11/23

$254

One-way flights from New Orleans to Greenville
Search for one-way flight options from New Orleans to Greenville. Find affordable one-way fares based on user searches. Data last updated November 24, 2025.

Sun 12/74:40 pmMSY - GSP

1 stop25h 43mBreeze Airways

Deal found 11/22

$113

Mon 3/98:00 amMSY - GSP

1 stop10h 38mBreeze Airways

Deal found 11/22

$114

Sat 12/206:40 amMSY - GSP

1 stop13h 11mMultiple Airlines

Deal found 11/24

$119

Sun 12/74:35 pmMSY - GSP

2 stops20h 35mMultiple Airlines

Deal found 11/22

$131

Fri 12/56:20 amMSY - GSP

1 stop6h 50mMultiple Airlines

Deal found 11/24

$150

Fri 12/125:15 amMSY - GSP

1 stop13h 08mMultiple Airlines

Deal found 11/24

$163

Sun 12/286:40 amMSY - GSP

2 stops31h 00mMultiple Airlines

Deal found 11/24

$173

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 12/4

2:02 pm-7:23 pm

1 stop28h 21m

Greenville

Sun 12/7

2:06 pm-10:27 pm

1 stop9h 21m

$210

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Mon 12/8

5:15 am-7:23 pm

1 stop13h 08m

Greenville

Fri 12/12

8:03 pm-9:42 pm

2 stops26h 39m

$222

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 3/4

7:27 pm-3:51 pm

1 stop19h 24m

Greenville

Mon 3/9

6:43 pm-8:55 pm

1 stop27h 12m

$255

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Mon 12/29

6:40 am-6:35 pm

1 stop10h 55m

Greenville

Fri 1/2

8:58 pm-8:17 am

1 stop12h 19m

$256

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Tue 12/30

5:00 pm-3:55 pm

2 stops21h 55m

Greenville

Fri 1/2

8:58 pm-8:17 am

1 stop12h 19m

$274

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Thu 3/5

6:15 am-3:51 pm

1 stop8h 36m

Greenville

Mon 3/9

6:43 pm-11:15 am

2 stops17h 32m

$303

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 3/4

9:30 am-5:40 pm

2 stops7h 10m

Greenville

Mon 3/9

6:25 am-12:40 pm

2 stops7h 15m

$329

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Wed 4/8

12:15 pm-9:22 pm

1 stop8h 07m

Greenville

Sun 4/12

6:30 am-1:23 pm

1 stop7h 53m

$367

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Mon 3/9

8:00 am-7:38 pm

1 stop10h 38m

$113

New OrleansGreenville

MSY - GSP

MSYGSP

New Orleans Louis Armstrong

Sat 12/20

6:40 am-8:51 pm

1 stop13h 11m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/22

Showing 1-10 of 17 results

Compare providers for flights from New Orleans to Greenville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Greenville in November.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on New Orleans-Greenville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on New Orleans-Greenville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from New Orleans-Greenville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on New Orleans-Greenville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

Currently, February is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $78). Flying from New Orleans to Greenville in June is currently the most expensive (average of $175). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to GSP?

It’s optimal to fly from New Orleans to Greenville in the morning. By choosing this option you can save up to 58% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,997 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

7,997 reviews

Delta

7.9

Good

7,997 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,046 reviews

Delta

7.9

Good

7,997 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

What are the cheapest airlines flying from New Orleans to Greenville round-trip?
According to our current data, Delta ($252), and American Airlines ($295) offers the cheapest pricing from New Orleans to Greenville. You may be able to fly from New Orleans to Greenville for 36% less than the average price by searching for these airlines.
Can I find deals for flights from New Orleans to Greenville that include hotel bookings?
Yes. In addition to deals on New Orleans to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from New Orleans to Greenville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Greenville.
Can I find deals for business class flights from New Orleans to Greenville?
Yes. Cheapflights offers flight deals from New Orleans to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from New Orleans to Greenville?
Currently, February is the cheapest month in which you can book a flight from New Orleans to Greenville (average of $78). Flying from New Orleans to Greenville in June is currently the most expensive (average of $175). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Simpsonville

Duncan

Greer

Seneca

Anderson

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Top 2 airlines flying from New Orleans to Greenville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$252	Average$419	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$295	Average$395	FlexibilityNo cancel fee	On-time71%

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$113+ Cheap flights from New Orleans to Greenville (MSY - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from New Orleans to Greenville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from New Orleans to Greenville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from New Orleans to Greenville

Cheapest flights from New Orleans to GreenvilleExplore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Greenville that are best for you.

Compare providers for flights from New Orleans to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Greenville in November.

Best time to book a flight from New Orleans to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from New Orleans with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Greenville

What is the cheapest month to book a flight from New Orleans to Greenville?

What is the cheapest time of day to fly from MSY to GSP?

Reviews of airlines servicing Greenville

Peruse reviews from past customers who have flown with Delta and American Airlines from New Orleans to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from New Orleans to Greenville round-trip?

Can I find deals for flights from New Orleans to Greenville that include hotel bookings?

How can I find direct flights from New Orleans to Greenville?

Can I find deals for business class flights from New Orleans to Greenville?

What is the cheapest month to book a flight from New Orleans to Greenville?

Traveling to a place near Greenville?

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Alternative routes for New Orleans to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from New Orleans to Greenville

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Cheapest flights from New Orleans to Greenville
Explore the most affordable flight options available from New Orleans to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.