$142+ Cheap flights from San Francisco (SFO) to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GCM
mars 13 — mars 201
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Francisco to Grand Cayman with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Grand Cayman
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to Grand CaymanExplore the most affordable flight options available from San Francisco to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on février 11, 2026.
Explore the most affordable flight options available from San Francisco to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on février 11, 2026.
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 2/2510:39 pm
SFO
- GCM
1 stop12h 16m
JetBlue
mar. 3/33:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/9![JetBlue logo]()
$434
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/107:20 pm
SFO
- GCM
2 stops14h 25m
Southwest
mar. 3/1712:40 pm
GCM
- SFO
2 stops13h 05m
Southwest
Deal found 2/10![Southwest logo]()
$500
This KAYAK deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 4/111:59 pm
SFO
- GCM
1 stop10h 46m
JetBlue
mar. 4/72:05 pm
GCM
- SFO
1 stop12h 53m
JetBlue
Deal found 2/8![JetBlue logo]()
$504
This FlightHub deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 4/184:15 pm
SFO
- GCM
1 stop16h 40m
Multiple Airlines
sam. 4/252:10 pm
GCM
- SFO
1 stop11h 46m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$506
This Orbitz deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 2/267:00 am
SFO
- GCM
1 stop28h 35m
JetBlue
mar. 3/33:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/7![JetBlue logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/145:47 pm
SFO
- GCM
2 stops20h 18m
Multiple Airlines
lun. 4/201:50 pm
GCM
- SFO
1 stop24h 55m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$530
This Travelocity deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/1611:14 pm
SFO
- GCM
1 stop11h 42m
JetBlue
lun. 3/232:40 pm
GCM
- SFO
1 stop22h 05m
JetBlue
Deal found 2/7![JetBlue logo]()
$534
Best flights from San Francisco to Grand CaymanDiscover carefully curated flight deals from San Francisco to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated février 11, 2026.
Discover carefully curated flight deals from San Francisco to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated février 11, 2026.
This KAYAK deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 2/2510:39 pm
SFO
- GCM
1 stop12h 16m
JetBlue
mar. 3/33:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/8![JetBlue logo]()
$434
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/277:15 pm
SFO
- GCM
2 stops14h 55m
Southwest
mer. 5/61:05 pm
GCM
- SFO
2 stops12h 30m
Southwest
Deal found 2/9![Southwest logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/145:47 pm
SFO
- GCM
2 stops20h 18m
Multiple Airlines
lun. 4/201:50 pm
GCM
- SFO
1 stop24h 55m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$530
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/107:20 pm
SFO
- GCM
2 stops14h 25m
Southwest
mar. 3/1712:40 pm
GCM
- SFO
2 stops13h 05m
Southwest
Deal found 2/10![Southwest logo]()
$500
This KAYAK deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 4/111:59 pm
SFO
- GCM
1 stop10h 46m
JetBlue
mar. 4/72:05 pm
GCM
- SFO
1 stop12h 53m
JetBlue
Deal found 2/8![JetBlue logo]()
$504
This Orbitz deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 2/267:00 am
SFO
- GCM
1 stop28h 35m
JetBlue
mar. 3/33:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/7![JetBlue logo]()
$529
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/79:15 pm
SFO
- GCM
2 stops12h 55m
Southwest
ven. 5/151:05 pm
GCM
- SFO
2 stops12h 00m
Southwest
Deal found 2/9![Southwest logo]()
$530
This Travelocity deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/1611:14 pm
SFO
- GCM
1 stop11h 42m
JetBlue
lun. 3/232:40 pm
GCM
- SFO
1 stop22h 05m
JetBlue
Deal found 2/7![JetBlue logo]()
$534
Last-minute flights from San Francisco to Grand CaymanDiscover last-minute flight deals from San Francisco to Grand Cayman. Data last updated février 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Grand Cayman. Data last updated février 11, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/1610:58 pm
SFO
- GCM
2 stops14h 07m
Multiple Airlines
jeu. 2/194:45 pm
GCM
- SFO
2 stops19h 48m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$591
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 2/2510:39 pm
SFO
- GCM
1 stop12h 16m
JetBlue
mar. 3/33:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/9![JetBlue logo]()
$434
This Orbitz deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 2/267:00 am
SFO
- GCM
1 stop28h 35m
JetBlue
mar. 3/33:15 pm
GCM
- SFO
1 stop11h 44m
JetBlue
Deal found 2/7![JetBlue logo]()
$529
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/107:20 pm
SFO
- GCM
2 stops14h 25m
Southwest
mar. 3/1712:40 pm
GCM
- SFO
2 stops13h 05m
Southwest
Deal found 2/10![Southwest logo]()
$500
This Orbitz deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/1011:30 pm
SFO
- GCM
2 stops35h 31m
JetBlue
mar. 3/172:25 pm
GCM
- SFO
1 stop21h 24m
JetBlue
Deal found 2/10![JetBlue logo]()
$554
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/1010:35 pm
SFO
- GCM
1 stop11h 12m
Delta
mar. 3/171:12 pm
GCM
- SFO
1 stop12h 07m
Delta
Deal found 2/10![Delta logo]()
$563
This Travelocity deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/1611:14 pm
SFO
- GCM
1 stop11h 42m
JetBlue
lun. 3/232:40 pm
GCM
- SFO
1 stop22h 05m
JetBlue
Deal found 2/7![JetBlue logo]()
$534
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/167:00 pm
SFO
- GCM
2 stops14h 10m
American Airlines
lun. 3/233:30 pm
GCM
- SFO
1 stop9h 46m
American Airlines
Deal found 2/8![American Airlines logo]()
$558
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 3/209:35 pm
SFO
- GCM
1 stop10h 10m
Delta
sam. 3/281:00 pm
GCM
- SFO
1 stop12h 34m
Delta
Deal found 2/9![Delta logo]()
$553
One-way flights from San Francisco to Grand CaymanSearch for one-way flight options from San Francisco to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated février 11, 2026.
Search for one-way flight options from San Francisco to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated février 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 3/116:00 am
SFO
- GCM
3 stops28h 57m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$142
This Priceline deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 3/1110:39 am
SFO
- GCM
1 stop24h 22m
JetBlue
Deal found 2/8![JetBlue logo]()
$198
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 4/56:55 pm
SFO
- GCM
1 stop15h 35m
United Airlines
Deal found 2/10![United Airlines logo]()
$229
This Priceline deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 2/1911:30 pm
SFO
- GCM
1 stop12h 04m
JetBlue
Deal found 2/8![JetBlue logo]()
$236
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 6/59:00 pm
SFO
- GCM
1 stop14h 55m
JetBlue
Deal found 2/9![JetBlue logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 2/196:15 am
SFO
- GCM
3 stops26h 20m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$284
This Air Canada deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 2/198:25 am
SFO
- GCM
2 stops25h 00m
Air Canada
Deal found 2/8![Air Canada logo]()
$288
This Air Canada deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 6/58:05 am
SFO
- GCM
2 stops25h 25m
Air Canada
Deal found 2/8![Air Canada logo]()
$322
This Air Canada deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 4/58:10 am
SFO
- GCM
2 stops24h 05m
Air Canada
Deal found 2/10![Air Canada logo]()
$342
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 6/58:13 pm
SFO
- GCM
2 stops12h 43m
American Airlines
Deal found 2/9![American Airlines logo]()
$354
Find flight deals from San Francisco to Grand Cayman
Keep the following information in mind while searching for San Francisco to Grand Cayman flight deals. Data was last updated février 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $434 (KAYAK) |
One-way from | $142 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $553 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated février 11, 2026.
Use the filters below to find and compare flights from San Francisco to Grand Cayman that are best for you.
Fly from
San Francisco
Fly to
Grand Cayman
Route
Depart
Return
Price
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
mer. 2/25
10:39 pm-1:55 pm
1 stop12h 16m
George Town Owen Roberts Intl
mar. 3/3
3:15 pm-11:59 pm
1 stop11h 44m
$434
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
lun. 4/27
7:15 pm-12:10 pm
2 stops14h 55m
George Town Owen Roberts Intl
mer. 5/6
1:05 pm-11:35 pm
2 stops12h 30m
$452
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
mar. 3/10
7:20 pm-11:45 am
2 stops14h 25m
George Town Owen Roberts Intl
mar. 3/17
12:40 pm-11:45 pm
2 stops13h 05m
$500
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
mer. 4/1
11:59 pm-12:45 pm
1 stop10h 46m
George Town Owen Roberts Intl
mar. 4/7
2:05 pm-12:58 am
1 stop12h 53m
$504
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
jeu. 2/26
7:00 am-2:35 pm
1 stop28h 35m
George Town Owen Roberts Intl
mar. 3/3
3:15 pm-11:59 pm
1 stop11h 44m
$529
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
mar. 4/14
5:47 pm-4:05 pm
2 stops20h 18m
George Town Owen Roberts Intl
lun. 4/20
1:50 pm-12:45 pm
1 stop24h 55m
$530
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
jeu. 5/7
9:15 pm-12:10 pm
2 stops12h 55m
George Town Owen Roberts Intl
ven. 5/15
1:05 pm-11:05 pm
2 stops12h 00m
$530
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
lun. 3/16
11:14 pm-12:56 pm
1 stop11h 42m
George Town Owen Roberts Intl
lun. 3/23
2:40 pm-10:45 am
1 stop22h 05m
$534
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
mer. 3/11
6:00 am-12:57 pm
3 stops28h 57m
$142
San FranciscoGeorge Town
SFO - GCM
SFOGCM
San Francisco
mer. 3/11
10:39 am-1:01 pm
1 stop24h 22m
$198
Showing 1-10 of 16 results
Best time to book a flight from San Francisco to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from San Francisco with our price prediction graph.
SFO-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Grand Cayman
SFO-zzLAW
SFO-GCM
What is the cheapest month to book a flight from San Francisco to Grand Cayman?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Grand Cayman (average of $405). Flying from San Francisco to Grand Cayman in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Grand Cayman
Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated février 11, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Francisco to Grand Cayman have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for San Francisco to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Grand Cayman by cabin class
Find flights from San Francisco to Grand Cayman, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Grand Cayman flights
Browse other San Francisco and Grand Cayman flight options. Last updated on février 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Grand Cayman
Discover the top 4 airlines that operate flights from San Francisco to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated février 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$465 | Average$491 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$491 | Average$659 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$511 | Average$654 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$511 | Average$648 | FlexibilityNo cancel fee | On-time69% |