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Grand Cayman

$289+ Cheap flights from Des Moines (DSM) to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Des Moines to Grand Cayman

Keep the following information in mind while searching for Des Moines to Grand Cayman flight deals. Data was last updated September 17, 2025.

Round-trip from

$546
(American Airlines)

One-way from

$289
(American Airlines)

Popular in

December

Cheapest in

November

Average price

$634
From Des Moines to Grand Cayman
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One-way flight from Des Moines to Grand Cayman
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Highest demand for flights based on searches. 16% potential increase in price ($146 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($61 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Grand Cayman

Cheapest flights from Des Moines to Grand Cayman
Explore the most affordable flight options available from Des Moines to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:42 amDSM - GCM
1 stop8h 07mAmerican Airlines
Sat 12/61:25 pmGCM - DSM
1 stop11h 04mAmerican Airlines
Deal found 9/16$546
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:00 amDSM - GCM
1 stop13h 28mAmerican Airlines
Sun 11/233:10 pmGCM - DSM
1 stop10h 11mAmerican Airlines
Deal found 9/16$551
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:00 amDSM - GCM
2 stops14h 28mAmerican Airlines
Mon 12/19:00 amGCM - DSM
2 stops15h 44mAmerican Airlines
Deal found 9/15$734
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:57 pmDSM - GCM
2 stops15h 53mAmerican Airlines
Sat 1/108:30 amGCM - DSM
2 stops15h 31mAmerican Airlines
Deal found 9/15$755
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:57 pmDSM - GCM
2 stops15h 53mAmerican Airlines
Sat 1/174:15 pmGCM - DSM
1 stop7h 10mAmerican Airlines
Deal found 9/15$780
This deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amDSM - GCM
1 stop7h 50mAmerican Airlines
Mon 1/53:45 pmGCM - DSM
1 stop9h 03mAmerican Airlines
Deal found 9/14$868

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to Grand Cayman that are best for you.

Fly from

Des Moines

Fly to

Grand Cayman

Route

Depart

Return

Price

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sat 11/29

5:42 am-2:49 pm

1 stop8h 07m

George Town Owen Roberts Intl

Sat 12/6

1:25 pm-11:29 pm

1 stop11h 04m

$546

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Thu 11/20

5:42 am-8:28 pm

2 stops13h 46m

George Town Owen Roberts Intl

Sun 11/23

3:36 pm-8:21 am

2 stops17h 45m

$555

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 2/22

7:00 am-12:35 pm

2 stops28h 35m

George Town Owen Roberts Intl

Wed 2/25

2:00 pm-10:28 pm

1 stop9h 28m

$580

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Mon 2/16

10:15 am-12:35 pm

2 stops25h 20m

George Town Owen Roberts Intl

Wed 2/25

2:00 pm-9:30 am

2 stops20h 30m

$580

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Wed 3/11

6:56 am-6:51 pm

2 stops11h 55m

George Town Owen Roberts Intl

Wed 3/18

8:30 am-10:50 pm

2 stops14h 20m

$580

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Tue 2/17

12:00 pm-12:35 pm

2 stops23h 35m

George Town Owen Roberts Intl

Wed 2/25

2:00 pm-10:28 pm

1 stop9h 28m

$580

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 3/15

6:20 pm-10:45 am

2 stops16h 25m

$289

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 3/15

6:45 pm-12:45 pm

1 stop18h 00m

$297

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 3/15

7:30 am-12:44 pm

3 stops29h 14m

$830

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Des Moines to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Grand Cayman

What is the cheapest month to book a flight from Des Moines to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Grand Cayman (average of $467). Flying from Des Moines to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LAW?

Find hourly flight availability from Des Moines to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Des Moines to Grand Cayman, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Grand Cayman. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Grand Cayman?

    If you book a flight to Grand Cayman from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Des Moines to Grand Cayman?

    Departing from Des Moines to Grand Cayman will take you 8h 07m. The distance from Des Moines to Grand Cayman is about 1697 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Des Moines to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Grand Cayman.

  • Can I find deals for business class flights from Des Moines to Grand Cayman?

    Yes. Cheapflights offers flight deals from Des Moines to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Grand Cayman (average of $467). Flying from Des Moines to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Grand Cayman

Discover the top 3 airlines that operate flights from Des Moines to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$507Average$634FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$555Average$605FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$575Average$671FlexibilityNo cancel feeOn-time71%

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