HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Grand Cayman

$605+ Cheap flights from Des Moines (DSM) to Grand Cayman

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
Jul 1 — Jul 81
Tue 7/1
Tue 7/8
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Grand Cayman with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Grand Cayman

Keep the following information in mind while searching for Des Moines to Grand Cayman flight deals. Data was last updated June 26, 2025.

Round-trip from

$605
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$667
From Des Moines to Grand Cayman
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Des Moines to Grand Cayman

Cheapest flights from Des Moines to Grand Cayman
Explore the most affordable flight options available from Des Moines to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2025.

This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:09 pmDSM - GCM
2 stops16h 56mAmerican Airlines
Sat 10/1812:45 pmGCM - DSM
1 stop8h 59mAmerican Airlines
Deal found 6/25$605

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2025.
Use the filters below to find and compare flights from Des Moines to Grand Cayman that are best for you.

Fly from

Des Moines

Fly to

Grand Cayman

Route

Depart

Return

Price

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 10/12

6:09 pm-11:05 am

2 stops16h 56m

George Town Owen Roberts Intl

Sat 10/18

12:45 pm-9:44 pm

1 stop8h 59m

$605

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/25

Best time to book a flight from Des Moines to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Grand Cayman

What is the cheapest time of day to fly from DSM to LAW?

Find hourly flight availability from Des Moines to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 26, 2025.

When flying from Des Moines to Grand Cayman, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated June 26, 2025.
Read reviews from past customers who have flown American Airlines from Des Moines to Grand Cayman. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
10.0
Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Grand Cayman?

    If you book a flight to Grand Cayman from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • Can I find deals for flights from Des Moines to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Des Moines to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Grand Cayman.

  • Can I find deals for business class flights from Des Moines to Grand Cayman?

    Yes. Cheapflights offers flight deals from Des Moines to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Grand Cayman (average of $467). Flying from Des Moines to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to George Town flights
Omaha to George Town flights
Moline to George Town flights

Top 2 airlines flying from Des Moines to Grand Cayman

Discover the top 2 airlines that operate flights from Des Moines to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$457Average$605FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$542Average$636FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.