$570+ Cheap flights from Panama City (PTY) to Frankfurt am Main
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — FRA
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Cheapest flights from Panama City to Frankfurt am MainExplore the most affordable flight options available from Panama City to Frankfurt am Main. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Panama City to Frankfurt am Main. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This KLM deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:45 pm -
1 stop12h 50m
Tue 2/210:15 am -
2 stops26h 08m
Deal found 11/1![Multiple Airlines logo]()
$1,021
This KLM deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop12h 50m
Mon 11/307:05 am -
2 stops19h 15m
Deal found 11/2![Multiple Airlines logo]()
$1,023
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:55 pm -
1 stop18h 30m
Mon 1/1810:20 am -
2 stops16h 00m
Deal found 10/30![KLM logo]()
$1,044
This KLM deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop12h 50m
Mon 11/2310:15 am -
2 stops16h 05m
Deal found 11/4![KLM logo]()
$1,045
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:55 am -
2 stops21h 05m
Mon 1/1811:05 am -
2 stops36h 07m
Deal found 10/30![United Airlines logo]()
$1,050
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:55 am -
2 stops22h 50m
Wed 12/91:30 pm -
2 stops31h 15m
Deal found 11/2![United Airlines logo]()
$1,051
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2211:55 pm -
2 stops25h 30m
Thu 1/71:30 pm -
1 stop36h 32m
Deal found 11/4![United Airlines logo]()
$1,053
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:00 am -
1 stop17h 10m
Thu 12/318:40 am -
2 stops36h 05m
Deal found 11/1![United Airlines logo]()
$1,057
This KLM deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:45 pm -
1 stop12h 50m
Wed 12/212:00 pm -
1 stop14h 20m
Deal found 11/3![Multiple Airlines logo]()
$1,060
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:00 am -
2 stops20h 20m
Sat 1/95:00 pm -
2 stops33h 02m
Deal found 11/4![United Airlines logo]()
$1,069
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2211:55 pm -
2 stops25h 30m
Tue 1/126:50 am -
2 stops19h 12m
Deal found 11/4![United Airlines logo]()
$1,071
Best flights from Panama City to Frankfurt am MainDiscover carefully curated flight deals from Panama City to Frankfurt am Main that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Panama City to Frankfurt am Main that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Turkish Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/110:00 pm -
1 stop36h 50m
Mon 2/1510:55 am -
2 stops36h 15m
Deal found 11/3![Turkish Airlines logo]()
$1,001
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:00 am -
1 stop17h 10m
Thu 12/318:40 am -
2 stops36h 05m
Deal found 11/1![United Airlines logo]()
$1,057
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1111:35 am -
1 stop18h 05m
Mon 1/259:45 am -
2 stops40h 17m
Deal found 11/3![United Airlines logo]()
$1,064
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:55 pm -
2 stops30h 05m
Wed 1/271:30 pm -
2 stops31h 15m
Deal found 11/3![United Airlines logo]()
$1,133
Last-minute flights from Panama City to Frankfurt am MainDiscover last-minute flight deals from Panama City to Frankfurt am Main. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Frankfurt am Main. Data last updated November 4, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:45 pm -
1 stop12h 50m
Tue 2/210:15 am -
2 stops26h 08m
Deal found 11/1![Multiple Airlines logo]()
$1,021
This KLM deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop12h 50m
Mon 11/307:05 am -
2 stops19h 15m
Deal found 11/2![Multiple Airlines logo]()
$1,023
This KLM deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 pm -
1 stop12h 50m
Mon 11/2310:15 am -
2 stops16h 05m
Deal found 11/4![KLM logo]()
$1,045
This KLM deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:45 pm -
1 stop12h 50m
Wed 12/212:00 pm -
1 stop14h 20m
Deal found 11/3![Multiple Airlines logo]()
$1,060
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:35 am -
1 stop18h 05m
Wed 12/911:05 am -
2 stops33h 40m
Deal found 11/2![United Airlines logo]()
$1,051
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:00 am -
2 stops19h 25m
Tue 1/121:50 pm -
1 stop30h 55m
Deal found 11/4![United Airlines logo]()
$1,069
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2211:55 pm -
2 stops25h 30m
Thu 1/71:30 pm -
1 stop36h 32m
Deal found 11/4![United Airlines logo]()
$1,053
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2211:55 pm -
2 stops25h 30m
Tue 1/126:50 am -
2 stops19h 12m
Deal found 11/4![United Airlines logo]()
$1,071
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:00 am -
2 stops20h 00m
Thu 12/318:40 am -
2 stops36h 05m
Deal found 11/1![United Airlines logo]()
$1,057
This KLM deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:55 pm -
1 stop18h 30m
Mon 1/1810:20 am -
2 stops16h 00m
Deal found 10/30![KLM logo]()
$1,044
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:55 am -
2 stops21h 05m
Mon 1/1811:05 am -
2 stops36h 07m
Deal found 10/30![United Airlines logo]()
$1,050
One-way flights from Panama City to Frankfurt am MainSearch for one-way flight options from Panama City to Frankfurt am Main. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Panama City to Frankfurt am Main. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:30 pm -
1 stop14h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Air Europa logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:30 pm -
2 stops52h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$574
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:30 pm -
2 stops28h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$599
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:30 pm -
2 stops52h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$602
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:30 pm -
2 stops52h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:30 pm -
2 stops28h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$626
This Air France deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:30 pm -
1 stop17h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Air France logo]()
$686
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:50 pm -
1 stop37h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Turkish Airlines logo]()
$750
Find flight deals from Panama City to Frankfurt am Main
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Frankfurt am Main (FK0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Round-trip from | $980 (Turkish Airlines) |
|---|---|
One-way from | $570 (Mytrip) |
Popular in | January |
Cheapest in | November |
Average price | $833 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Frankfurt am Main that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Panama City to Frankfurt am Main that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Tue 12/1
9:30 pm-8:20 am
2 stops28h 50m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$599
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Wed 12/2
9:30 pm-8:20 am
3 stops28h 50m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$641
Quickest round-trip
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Wed 12/2
6:45 pm-1:35 pm
1 stop12h 50m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$686
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Tue 12/22
6:50 pm-1:55 pm
1 stop37h 05m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$750
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Thu 3/18
6:45 pm-6:00 pm
1 stop17h 15m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$758
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Fri 3/12
6:45 pm-5:55 pm
1 stop17h 10m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$758
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Wed 3/17
10:30 pm-10:25 pm
2 stops17h 55m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$790
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Mon 12/14
10:00 pm-9:30 am
1 stop29h 30m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$813
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Fri 12/18
10:00 pm-4:50 pm
1 stop36h 50m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$813
Panama CityFrankfurt am Main
PTY Panama City Tocumen Intl - FRA Frankfurt am Main
PTYFRA
Panama City Tocumen Intl
Sat 12/19
6:50 pm-1:55 pm
1 stop37h 05m
Frankfurt am Main
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$856
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Panama City to Frankfurt am Main
Have a flexible travel schedule? Discover the best time to fly to Frankfurt am Main from Panama City with our price prediction graph.
PTY-FK0
PTY-FRA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Frankfurt am Main
PTY-FK0
PTY-FRA
What is the cheapest month to book a flight from Panama City to Frankfurt am Main?
Currently, November is the cheapest month in which you can book a flight from Panama City to Frankfurt am Main (average of $833). Flying from Panama City to Frankfurt am Main in January is currently the most expensive (average of $1,341). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City to Frankfurt am Main?
Airfare is typical for this route at the moment.
Panama City to Frankfurt am Main flights typically cost between $676 and $1,251 in February.The cheapest round-trip price found within the last 5 days was $980 on Turkish Airlines (Feb 1-Feb 15).
How often are flights from Panama City to Frankfurt am Main delayed?
About 8% of weekly flights between Panama City and Frankfurt am Main have experienced delays in the past year, with the average delay time being 149 minutes.
What is the most punctual flight time for Panama City to Frankfurt am Main flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Frankfurt am Main flights?
Over the last year, Condor have had the lowest number of delays on this route, with just 8% of flights being delayed.
How far ahead should I book a flight from Panama City to Frankfurt am Main?
The best time to book flights from Panama City to Frankfurt am Main is 34 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Frankfurt am Main
Get insights into the airlines that provide service to Frankfurt am Main. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Frankfurt am Main. Reviews last updated November 4, 2026.
Read reviews from past customers who have flown KLM,Turkish Airlines, andAir Europa from Panama City to Frankfurt am Main. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Crew
8.4
Comfort
7.7
Entertainment
7.2
Overall
7.8
Food
7.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Boarding
7.8
Crew
8.4
Comfort
7.7
Entertainment
7.2
Overall
7.8
Food
7.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Boarding
7.8
Crew
8.4
Comfort
7.7
Entertainment
7.2
Overall
7.8
Food
7.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Boarding
7.8
Crew
8.4
Comfort
7.7
Entertainment
7.2
Overall
7.8
Food
7.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Related info for your journey
Find useful and relevant information for your journey from Panama City to Frankfurt am Main. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Frankfurt am Main
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Complete your trip
Complete your trip to Frankfurt am Main by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama City to Frankfurt am Main, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Frankfurt am Main flights
Browse other Panama City and Frankfurt am Main flight options. Last updated on November 4, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama City to Frankfurt am Main
Discover the top 3 airlines that operate flights from Panama City to Frankfurt am Main. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$820 | Average$920 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$824 | Average$880 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$877 | Average$1,259 | FlexibilityNo cancel fee | On-time83% |