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Florida Keys

$432+ Cheap flights from La Crosse (LSE) to Florida Keys

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — EYW
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from La Crosse to Florida Keys

Keep the following information in mind while searching for La Crosse to Florida Keys flight deals. Data was last updated September 17, 2025.

Round-trip from

$432
(American Airlines)
From La Crosse to Florida Keys
Search Deals

Find flight deals from La Crosse to Florida Keys

Cheapest flights from La Crosse to Florida Keys
Explore the most affordable flight options available from La Crosse to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amLSE - MIA
1 stop7h 50mAmerican Airlines
Sat 10/42:16 pmMIA - LSE
1 stop8h 48mAmerican Airlines
Deal found 9/14$432
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amLSE - EYW
2 stops10h 46mAmerican Airlines
Tue 9/2312:24 pmEYW - LSE
2 stops10h 44mAmerican Airlines
Deal found 9/16$441
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amLSE - EYW
1 stop6h 20mAmerican Airlines
Sat 12/134:20 pmEYW - LSE
2 stops8h 32mAmerican Airlines
Deal found 9/14$496
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:00 amLSE - EYW
2 stops10h 46mAmerican Airlines
Tue 9/2312:24 pmEYW - LSE
2 stops10h 44mAmerican Airlines
Deal found 9/16$500
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amLSE - MIA
1 stop5h 13mAmerican Airlines
Sun 10/55:16 pmMIA - LSE
1 stop7h 01mAmerican Airlines
Deal found 9/16$517
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amLSE - EYW
2 stops9h 07mAmerican Airlines
Mon 10/201:38 pmEYW - LSE
2 stops10h 48mAmerican Airlines
Deal found 9/16$654
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:00 amLSE - EYW
2 stops9h 17mAmerican Airlines
Mon 10/61:25 pmEYW - LSE
2 stops11h 01mAmerican Airlines
Deal found 9/17$716
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:21 pmLSE - EYW
2 stops22h 25mAmerican Airlines
Tue 9/236:17 pmEYW - LSE
2 stops16h 02mAmerican Airlines
Deal found 9/16$755

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from La Crosse to Florida Keys that are best for you.

Fly from

La Crosse

Fly to

Florida Keys

Route

Depart

Return

Price

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Tue 9/30

6:00 am-2:50 pm

1 stop7h 50m

Miami

Sat 10/4

2:16 pm-10:04 pm

1 stop8h 48m

$432

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Sat 1/10

11:37 am-7:14 pm

1 stop6h 37m

Miami

Sun 1/18

6:30 am-11:02 am

1 stop5h 32m

$451

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Thu 1/15

11:37 am-6:10 pm

1 stop5h 33m

Miami

Sun 1/18

6:30 am-11:02 am

1 stop5h 32m

$484

La CrosseKey West

LSE - EYW

LSEEYW

La Crosse

Tue 12/9

6:00 am-1:20 pm

1 stop6h 20m

Key West

Sat 12/13

4:20 pm-11:52 pm

2 stops8h 32m

$496

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Wed 10/1

6:00 am-12:13 pm

1 stop5h 13m

Miami

Sun 10/5

5:16 pm-11:17 pm

1 stop7h 01m

$517

La CrosseKey West

LSE - EYW

LSEEYW

La Crosse

Wed 10/15

6:00 am-4:07 pm

2 stops9h 07m

Key West

Mon 10/20

1:38 pm-11:26 pm

2 stops10h 48m

$654

La CrosseKey West

LSE - EYW

LSEEYW

La Crosse

Thu 10/2

6:39 pm-10:54 am

3 stops15h 15m

Key West

Mon 10/6

4:57 pm-11:26 pm

2 stops7h 29m

$1,021

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from La Crosse to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to Florida Keys
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated September 17, 2025.
See what other customers who have flown with American Airlines from La Crosse to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to Florida Keys?

    La Crosse (LSE) is the airport you will fly out of if you book a flight from La Crosse to Florida Keys. It is only a 5.4 mi journey to La Crosse (LSE) from La Crosse’s city center.

  • How long is the flight from La Crosse to Florida Keys?

    For as low as $432, American Airlines can have you in Florida Keys from La Crosse in 7h 50m. Airlines will cover a distance of 1392 mi.

  • Can I find deals for flights from La Crosse to Florida Keys that include hotel bookings?

    Yes. In addition to deals on La Crosse to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Florida Keys.

  • Can I find deals for business class flights from La Crosse to Florida Keys?

    Yes. Cheapflights offers flight deals from La Crosse to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from La Crosse to Florida Keys (average of $328). Flying from La Crosse to Florida Keys in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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