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Florida Keys

$418+ Cheap flights from La Crosse (LSE) to Florida Keys

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — EYW
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheap flight deals from La Crosse to Florida Keys

Keep the following information in mind while searching for La Crosse to Florida Keys flight deals. Data was last updated January 7, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$418
(American Airlines)
Provider with most accurate pricing for La Crosse-Miami flight deals.
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Provider most trusted by Cheapflights users for La Crosse-Miami flights.
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From La Crosse to Florida Keys
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Find flight deals from La Crosse to Florida Keys

Cheapest flights from La Crosse to Florida Keys
Explore the most affordable flight options available from La Crosse to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:20 amLSE - MIA
1 stop6h 35mAmerican Airlines
Tue 2/243:53 pmMIA - LSE
1 stop8h 43mAmerican Airlines
Deal found 1/6$418
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:00 amLSE - EYW
1 stop8h 25mAmerican Airlines
Tue 2/176:54 pmEYW - LSE
1 stop5h 42mAmerican Airlines
Deal found 1/5$440
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:08 pmLSE - MIA
1 stop5h 35mAmerican Airlines
Tue 2/104:50 pmMIA - LSE
1 stop6h 26mAmerican Airlines
Deal found 1/6$445
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1311:31 amLSE - MIA
1 stop6h 34mAmerican Airlines
Mon 2/166:19 amMIA - LSE
1 stop5h 42mAmerican Airlines
Deal found 1/6$484
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:31 amLSE - MIA
1 stop6h 34mAmerican Airlines
Sat 3/146:19 amMIA - LSE
1 stop5h 43mAmerican Airlines
Deal found 1/5$488
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/105:08 pmLSE - MIA
1 stop5h 35mAmerican Airlines
Sun 1/188:39 amMIA - LSE
1 stop8h 37mAmerican Airlines
Deal found 1/7$515
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:09 amLSE - MIA
1 stop6h 46mAmerican Airlines
Sat 3/216:19 amMIA - LSE
1 stop5h 43mAmerican Airlines
Deal found 1/7$518
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/216:00 amLSE - EYW
2 stops9h 49mAmerican Airlines
Sun 1/256:06 amEYW - LSE
2 stops11h 10mAmerican Airlines
Deal found 1/6$623
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:35 amLSE - EYW
1 stop5h 44mAmerican Airlines
Sat 3/286:49 pmEYW - LSE
1 stop5h 47mAmerican Airlines
Deal found 1/5$782

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from La Crosse to Florida Keys that are best for you.

Fly from

La Crosse

Fly to

Florida Keys

Route

Depart

Return

Price

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Sat 4/11

10:05 am-4:35 pm

1 stop5h 30m

Miami

Wed 4/15

3:53 pm-11:54 pm

1 stop9h 01m

$418

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Sat 2/21

5:20 am-12:55 pm

1 stop6h 35m

Miami

Tue 2/24

3:53 pm-11:36 pm

1 stop8h 43m

$418

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Wed 3/11

5:09 am-12:55 pm

1 stop6h 46m

Miami

Wed 3/18

6:19 am-11:01 am

1 stop5h 42m

$418

La CrosseKey West

LSE - EYW

LSEEYW

La Crosse

Tue 2/10

6:00 am-3:25 pm

1 stop8h 25m

Key West

Tue 2/17

6:54 pm-11:36 pm

1 stop5h 42m

$440

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Wed 2/4

5:08 pm-11:43 pm

1 stop5h 35m

Miami

Tue 2/10

4:50 pm-10:16 pm

1 stop6h 26m

$445

La CrosseKey West

LSE - EYW

LSEEYW

La Crosse

Wed 1/21

6:00 am-4:49 pm

2 stops9h 49m

Key West

Sun 1/25

6:06 am-4:16 pm

2 stops11h 10m

$623

La CrosseKey West

LSE - EYW

LSEEYW

La Crosse

Sat 3/21

11:35 am-6:19 pm

1 stop5h 44m

Key West

Sat 3/28

6:49 pm-11:36 pm

1 stop5h 47m

$782

La CrosseMiami

LSE - MIA

LSEMIA

La Crosse

Sat 4/4

11:35 am-7:08 pm

1 stop6h 33m

$433

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Best time to book a flight from La Crosse to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to Florida Keys
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 7, 2026.
See what other customers who have flown with American Airlines from La Crosse to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,088 reviews

Overall

7.2

Food

6.4

Crew

8.0

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
11,088 reviews
American Airlines
7.2
Good
11,088 reviews

Overall

7.2

Food

6.4

Crew

8.0

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to Florida Keys?

    La Crosse (LSE) is the airport you will fly out of if you book a flight from La Crosse to Florida Keys. It is only a 5.4 mi journey to La Crosse (LSE) from La Crosse’s city center.

  • How long is the flight from La Crosse to Florida Keys?

    For as low as $418, American Airlines can have you in Florida Keys from La Crosse in 5h 30m. Airlines will cover a distance of 1392 mi.

  • Can I find deals for flights from La Crosse to Florida Keys that include hotel bookings?

    Yes. In addition to deals on La Crosse to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Florida Keys.

  • Can I find deals for business class flights from La Crosse to Florida Keys?

    Yes. Cheapflights offers flight deals from La Crosse to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for La Crosse to Florida Keys

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Top airline flying from La Crosse to Florida Keys

Discover the top airline that operate flights from La Crosse to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$415Average$519FlexibilityNo cancel feeOn-time71%

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