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$128+ Cheap flights from Santiago (SCL) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CUZ
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Cusco Velazco Astete are usually found in November or March, booked 80 days in advance, depart on a Tuesday or Saturday and return on a Monday

Cheap flight deals from Santiago to Cuzco

Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This JetSMART deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:29 pmSCL - CUZ
1 stop10h 57mJetSMART
Wed 1/148:57 pmCUZ - SCL
1 stop21h 47mJetSMART
Deal found 12/28$503
This Sky Airline deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:10 pmSCL - CUZ
1 stop11h 20mSky Airline
Tue 3/319:45 pmCUZ - SCL
2 stops12h 15mSky Airline
Deal found 12/28$558

Find flight deals from Santiago to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$263
(Sky Airline)

One-way from

$128
(FlightHub)

Popular in

January

Cheapest in

November

Average price

$290

Good round-trip deal

$458 or less

Good one-way deal

$150 or less
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Cusco Velazco Astete flight deals.
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Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Cusco Velazco Astete flights.
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From Santiago Arturo Merino Benitez to Cusco Velazco Astete
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One-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete
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Highest demand for flights based on searches. 6% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Santiago

Fly to

Cuzco

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 4/26

12:35 am-8:40 pm

2 stops21h 05m

Cusco Velazco Astete

Sat 5/2

7:05 am-9:10 pm

1 stop13h 05m

$262

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 4/17

11:30 am-8:40 pm

1 stop10h 10m

Cusco Velazco Astete

Fri 4/24

9:20 pm-11:00 am

2 stops12h 40m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 4/6

12:55 am-4:15 pm

2 stops16h 20m

Cusco Velazco Astete

Mon 4/13

6:30 pm-11:00 am

2 stops15h 30m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 4/23

12:35 am-8:40 pm

2 stops21h 05m

Cusco Velazco Astete

Fri 5/1

9:20 pm-1:45 pm

1 stop15h 25m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 4/14

12:35 am-4:15 pm

2 stops16h 40m

Cusco Velazco Astete

Sat 4/18

9:20 pm-1:45 pm

1 stop15h 25m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 4/7

12:35 am-11:25 am

2 stops11h 50m

Cusco Velazco Astete

Wed 4/15

6:30 pm-11:00 am

2 stops15h 30m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 3/17

1:35 am-5:10 pm

2 stops17h 35m

Cusco Velazco Astete

Wed 3/25

7:05 am-10:15 pm

1 stop13h 10m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 4/7

12:35 am-11:25 am

2 stops11h 50m

Cusco Velazco Astete

Sun 4/12

4:50 pm-11:00 am

2 stops17h 10m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 3/8

1:35 am-9:05 pm

2 stops21h 30m

Cusco Velazco Astete

Mon 3/16

9:45 pm-12:00 pm

2 stops12h 15m

$263

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 3/17

1:35 am-5:10 pm

2 stops17h 35m

Cusco Velazco Astete

Mon 3/23

9:45 pm-2:40 pm

1 stop14h 55m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 18 results
1
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Compare providers for flights from Santiago to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Cuzco in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-Cusco flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Santiago-Cusco flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Santiago-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Cusco flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Cuzco. Price data was last updated on December 26, 2025.

The price you pay for your flight from Santiago to Cusco may vary depending on when you book. For the best chance of a lower fare, look to book 80 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of $165). Flying from Santiago to Cusco in September is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Find hourly flight availability from Santiago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 30, 2025.

When flying from Santiago to Cusco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santiago to Cusco?

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated December 30, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,896 reviews

Crew

8.0

Food

6.7

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,896 reviews
LATAM Airlines
7.5
Good
1,896 reviews

Crew

8.0

Food

6.7

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Santiago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Cusco?

    Airlines like Sky Airline fly from Santiago to Cusco in about 21h 05m. The time it takes to get you to your destination can typically vary by up to . The distance between Santiago and Cusco is about 1373 mi.

  • What are the cheapest airlines flying from Santiago to Cusco round-trip?

    Currently priced at $192, Sky Airline will fly you from Santiago to Cusco and back. In addition to Sky Airline, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $207. Sky Airline is priced at 31% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Santiago to Cusco one-way?

    The cheapest airline one-way is JetSMART, with whom users have recently found tickets for as low as $31. However, be on the lookout for offers from Sky Airline and LATAM Airlines, as they are both options that can get you from Santiago to Cusco for a low price.

  • What are the cheapest flights from Santiago to Cusco?

    Looking at all options, your cheapest flight can be booked for $121. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $280 on average, our data indicates $349 when flying from Santiago to Cusco.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of $165). Flying from Santiago to Cusco in September is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Cuzco

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Santiago to Lima flights

Top 2 airlines flying from Santiago to Cuzco

Discover the top 2 airlines that operate flights from Santiago to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Sky AirlineCheapest$192Average$256FlexibilityNo cancel feeOn-time73%
LATAM AirlinesCheapest$207Average$332FlexibilityNo cancel feeOn-time81%

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