What are the cheapest airlines flying from Santiago to Cusco round-trip?

Currently priced at $233, Sky Airline will fly you from Santiago to Cusco and back. In addition to Sky Airline, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $269. Sky Airline is priced at 16% lower than the current average price of a flight leaving 3 months from now.

What is the cheapest day to fly from Santiago to Cusco?

Travelers seeking maximum savings on their Santiago to Cusco flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Cusco ranges from 0.0 - 5.5 inches per month. January is typically the wettest month, when rainfall can reach 5.5 in. May is typically the driest time to visit Cusco when rainfall is around 0.0 in.

If weather is an important factor for your trip to Cusco, use this chart to help with planning. For those seeking warmer temperatures, October is the ideal time of year to visit, when temperatures reach an average of 55.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

What are the cheapest flights from Santiago to Cusco?

Looking at all options, your cheapest flight can be booked for $147. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $221 on average our data indicates $158 when flying from Santiago to Cusco.

What is the cheapest day to fly round-trip from Santiago to Cusco?

Friday is generally a great day to depart. Flying on this day could help you save up to 34%.

What is the cheapest month to fly from Santiago to Cusco?

March can be a great time to fly to Cusco from Santiago with a flight ticket averaging about $278. Cheapflights users have found deals in the month of March for as cheap as $176. The most expensive prices can be found in the month of January.

Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to Cuzco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

Can I find deals for business class flights from Santiago to Cuzco?

Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$31+ Cheap Flights from Santiago to Cusco

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Find cheap flights from Santiago to Cuzco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Cusco Velazco Astete are usually found in March or November, booked 82 days in advance, depart on a Saturday or Tuesday and return on a Monday

Cheap flight deals from Santiago to Cuzco

Round-trip from	$235 (Mytrip)
One-way from	$31 (FlightHub)
Popular in	January
Cheapest in	March
Average price	$266
Good one-way deal	$150 or less

From Santiago Arturo Merino Benitez to Cusco Velazco Astete

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One-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($12 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Cusco Velazco Astete.

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Find flight deals from Santiago to Cuzco

Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Tue 9/212:35 amSCL - CUZ

2 stops19h 55mMultiple Airlines

Thu 9/44:42 pmCUZ - SCL

1 stop10h 19mMultiple Airlines

Deal found 8/13

$235

Tue 9/231:35 amSCL - CUZ

2 stops19h 30mSky Airline

Sun 9/286:25 pmCUZ - SCL

1 stop18h 20mSky Airline

Deal found 8/13

$236

Sun 9/289:15 pmSCL - CUZ

1 stop24h 40mSky Airline

Sun 10/512:05 pmCUZ - SCL

1 stop24h 40mSky Airline

Deal found 8/13

$237

Mon 9/18:15 pmSCL - CUZ

2 stops13h 55mSky Airline

Fri 9/58:20 pmCUZ - SCL

1 stop16h 25mSky Airline

Deal found 8/12

$238

Thu 10/91:35 amSCL - CUZ

2 stops20h 20mSky Airline

Wed 10/157:10 amCUZ - SCL

1 stop13h 00mSky Airline

Deal found 8/11

$239

Mon 10/271:30 amSCL - CUZ

2 stops20h 30mSky Airline

Sun 11/212:10 pmCUZ - SCL

2 stops22h 05mSky Airline

Deal found 8/14

$240

Thu 11/61:35 amSCL - CUZ

2 stops16h 30mSky Airline

Fri 11/1412:10 pmCUZ - SCL

2 stops22h 05mSky Airline

Deal found 8/14

$242

Mon 8/2512:45 amSCL - CUZ

2 stops16h 15mSky Airline

Tue 9/27:30 pmCUZ - SCL

2 stops14h 50mSky Airline

Deal found 8/12

$244

Sat 11/2212:30 pmSCL - CUZ

1 stop9h 30mSky Airline

Sun 11/305:55 pmCUZ - SCL

2 stops16h 20mSky Airline

Deal found 8/11

$246

Best flights from Santiago to Cuzco
Discover carefully curated flight deals from Santiago to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Mon 9/291:45 amSCL - CUZ

2 stops20h 10mSky Airline

Mon 10/612:05 pmCUZ - SCL

1 stop15h 55mSky Airline

Deal found 8/14

$235

Tue 9/212:35 amSCL - CUZ

2 stops19h 55mMultiple Airlines

Thu 9/44:42 pmCUZ - SCL

1 stop10h 19mMultiple Airlines

Deal found 8/13

$235

Mon 10/205:55 amSCL - CUZ

1 stop16h 00mSky Airline

Mon 10/278:45 pmCUZ - SCL

1 stop15h 55mSky Airline

Deal found 8/13

$235

Tue 9/231:35 amSCL - CUZ

2 stops19h 30mSky Airline

Sun 9/286:25 pmCUZ - SCL

1 stop18h 20mSky Airline

Deal found 8/13

$236

Sun 9/289:15 pmSCL - CUZ

1 stop24h 40mSky Airline

Sun 10/512:05 pmCUZ - SCL

1 stop24h 40mSky Airline

Deal found 8/13

$237

Sat 9/279:15 pmSCL - CUZ

1 stop11h 25mSky Airline

Sat 10/45:50 pmCUZ - SCL

1 stop10h 10mSky Airline

Deal found 8/13

$237

Fri 10/245:55 amSCL - CUZ

1 stop16h 00mSky Airline

Fri 10/318:45 pmCUZ - SCL

1 stop15h 55mSky Airline

Deal found 8/13

$237

Wed 10/151:40 amSCL - CUZ

2 stops17h 25mSky Airline

Mon 10/208:40 pmCUZ - SCL

1 stop12h 40mSky Airline

Deal found 8/13

$237

Mon 10/61:45 amSCL - CUZ

2 stops20h 10mSky Airline

Tue 10/145:50 pmCUZ - SCL

1 stop10h 10mSky Airline

Deal found 8/12

$238

Wed 10/291:30 amSCL - CUZ

2 stops20h 30mSky Airline

Tue 11/412:10 pmCUZ - SCL

2 stops22h 05mSky Airline

Deal found 8/12

$238

Last-minute flights from Santiago to Cuzco
Discover last-minute flight deals from Santiago to Cuzco. Data last updated August 14, 2025 and is based on user searches.

Tue 8/198:15 pmSCL - CUZ

1 stop13h 55mSky Airline

Mon 8/254:45 pmCUZ - SCL

2 stops15h 40mSky Airline

Deal found 8/13

$266

Tue 8/194:55 amSCL - CUZ

1 stop12h 05mSky Airline

Sat 8/239:55 amCUZ - SCL

1 stop10h 20mSky Airline

Deal found 8/14

$267

Wed 8/202:40 pmSCL - CUZ

Nonstop3h 35mLATAM Airlines

Wed 8/271:05 pmCUZ - SCL

1 stop6h 50mLATAM Airlines

Deal found 8/13

$258

Wed 8/208:15 pmSCL - CUZ

1 stop12h 20mSky Airline

Thu 8/285:10 pmCUZ - SCL

2 stops15h 15mSky Airline

Deal found 8/12

$263

Wed 8/2012:40 amSCL - CUZ

2 stops16h 45mSky Airline

Wed 8/275:15 pmCUZ - SCL

2 stops15h 10mSky Airline

Deal found 8/13

$269

Wed 8/209:40 pmSCL - CUZ

1 stop10h 40mMultiple Airlines

Wed 8/279:55 amCUZ - SCL

2 stops22h 30mMultiple Airlines

Deal found 8/13

$272

Fri 8/228:15 pmSCL - CUZ

2 stops13h 55mSky Airline

Fri 8/2910:25 pmCUZ - SCL

1 stop14h 20mSky Airline

Deal found 8/14

$274

Mon 8/2512:45 amSCL - CUZ

2 stops16h 15mSky Airline

Tue 9/27:30 pmCUZ - SCL

1 stop8h 30mSky Airline

Deal found 8/12

$244

Thu 8/2812:35 amSCL - CUZ

2 stops31h 05mSky Airline

Wed 9/39:55 amCUZ - SCL

1 stop10h 20mSky Airline

Deal found 8/14

$239

Mon 9/18:15 pmSCL - CUZ

2 stops13h 55mSky Airline

Fri 9/58:20 pmCUZ - SCL

1 stop16h 25mSky Airline

Deal found 8/12

$238

Tue 9/212:35 amSCL - CUZ

2 stops19h 55mMultiple Airlines

Thu 9/44:42 pmCUZ - SCL

1 stop10h 19mMultiple Airlines

Deal found 8/13

$235

Mon 9/81:45 amSCL - CUZ

1 stop31h 50mSky Airline

Tue 9/167:25 amCUZ - SCL

1 stop12h 50mSky Airline

Deal found 8/11

$240

One-way flights from Santiago to Cuzco
Search for one-way flight options from Santiago to Cuzco. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Mon 10/65:51 amSCL - CUZ

1 stop16h 28mJetSMART

Deal found 8/13

$31

Tue 10/75:51 amSCL - CUZ

1 stop17h 13mJetSMART

Deal found 8/13

$33

Sun 11/91:35 amSCL - CUZ

2 stops17h 35mSky Airline

Deal found 8/14

$115

Sun 9/71:35 amSCL - CUZ

2 stops20h 20mSky Airline

Deal found 8/13

$116

Mon 10/612:40 pmSCL - CUZ

1 stop10h 50mLATAM Airlines

Deal found 8/14

$117

Wed 9/102:35 pmSCL - CUZ

1 stop8h 20mLATAM Airlines

Deal found 8/11

$124

Tue 8/2612:35 amSCL - CUZ

2 stops16h 55mSky Airline

Deal found 8/13

$131

Sun 10/51:35 amSCL - CUZ

2 stops30h 50mSky Airline

Deal found 8/14

$136

Sun 8/318:15 pmSCL - CUZ

1 stop11h 25mSky Airline

Deal found 8/14

$141

Sat 10/41:35 amSCL - CUZ

2 stops20h 20mSky Airline

Deal found 8/14

$142

Fly from

Fly to

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 9/29

1:45 am-7:55 pm

2 stops20h 10m

Cusco Velazco Astete

Mon 10/6

12:05 pm-6:00 am

1 stop15h 55m

$235

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 9/2

12:35 am-7:30 pm

2 stops19h 55m

Cusco Velazco Astete

Thu 9/4

4:42 pm-4:01 am

1 stop10h 19m

$235

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 10/20

5:55 am-7:55 pm

1 stop16h 00m

Cusco Velazco Astete

Mon 10/27

8:45 pm-2:40 pm

1 stop15h 55m

$235

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 9/23

1:35 am-7:05 pm

2 stops19h 30m

Cusco Velazco Astete

Sun 9/28

6:25 pm-2:45 pm

1 stop18h 20m

$236

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 9/28

9:15 pm-7:55 pm

1 stop24h 40m

Cusco Velazco Astete

Sun 10/5

12:05 pm-2:45 pm

1 stop24h 40m

$237

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 9/27

9:15 pm-6:40 am

1 stop11h 25m

Cusco Velazco Astete

Sat 10/4

5:50 pm-6:00 am

1 stop10h 10m

$237

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 10/24

5:55 am-7:55 pm

1 stop16h 00m

Cusco Velazco Astete

Fri 10/31

8:45 pm-2:40 pm

1 stop15h 55m

$237

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 10/15

1:40 am-5:05 pm

2 stops17h 25m

Cusco Velazco Astete

Mon 10/20

8:40 pm-11:20 am

1 stop12h 40m

$237

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 10/6

1:45 am-7:55 pm

2 stops20h 10m

Cusco Velazco Astete

Tue 10/14

5:50 pm-6:00 am

1 stop10h 10m

$238

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 10/29

1:30 am-8:00 pm

2 stops20h 30m

Cusco Velazco Astete

Tue 11/4

12:10 pm-12:15 pm

2 stops22h 05m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 15 results

Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

The price you pay for your flight from Santiago to Cusco may vary depending on when you book. For the best chance of a lower fare, look to book 82 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, February is the cheapest month in which you can book a flight from Santiago to Cusco (average of $789). Flying from Santiago to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

One of the essential ways to save on airfare from Santiago to Cusco is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 25% on airfare.

Reviews of airlines servicing Cuzco

Peruse reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

LATAM Airlines

7.5

Good

1,840 reviews

Reviews

1 / 20

4.0

Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

LATAM Airlines

7.5

Good

1,840 reviews

LATAM Airlines

7.5

Good

1,840 reviews

Reviews

1 / 20

4.0

Okay

Murilo,Jun 2025

SFO - LAX

Related info for your journey

What are the cheapest airlines flying from Santiago to Cusco round-trip?
Currently priced at $233, Sky Airline will fly you from Santiago to Cusco and back. In addition to Sky Airline, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $269. Sky Airline is priced at 16% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest flights from Santiago to Cusco?
Looking at all options, your cheapest flight can be booked for $147. While the most popular route (Santiago Arturo Merino Benitez - Cusco Velazco Astete) can be booked for $221 on average our data indicates $158 when flying from Santiago to Cusco.
Can I find deals for flights from Santiago to Cuzco that include hotel bookings?
Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to Cuzco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.
Can I find deals for business class flights from Santiago to Cuzco?
Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to Cusco?
Currently, February is the cheapest month in which you can book a flight from Santiago to Cusco (average of $789). Flying from Santiago to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

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Top 2 airlines flying from Santiago to Cuzco

Airline	Cheapest	Average	Flexibility	On-time
Sky Airline	Cheapest$233	Average$286	FlexibilityNo cancel fee	On-time73%
LATAM Airlines	Cheapest$269	Average$344	FlexibilityNo cancel fee	On-time81%

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$31+ Cheap flights from Santiago (SCL) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago to Cuzco with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Cusco Velazco Astete are usually found in March or November, booked 82 days in advance, depart on a Saturday or Tuesday and return on a Monday

Cheap flight deals from Santiago to Cuzco

Round-trip from

One-way from

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Cheapest in

Average price

Good one-way deal

Find flight deals from Santiago to Cuzco

Cheapest flights from Santiago to CuzcoExplore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Cuzco. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Santiago to Cusco?

What is the cheapest time of day to fly from SCL to CUZ?

Find hourly flight availability from Santiago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated August 14, 2025.

Peruse reviews from past customers who have flown with LATAM Airlines from Santiago to Cusco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santiago to Cusco round-trip?

What are the cheapest flights from Santiago to Cusco?

Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

How can I find direct flights from Santiago to Cuzco?

Can I find deals for business class flights from Santiago to Cuzco?

What is the cheapest month to book a flight from Santiago to Cusco?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Cuzco

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Top 2 airlines flying from Santiago to Cuzco

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Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.