How long is the flight from San Francisco to Cusco?

A quick flight from San Francisco to Cusco can take about 17h 05m. Avianca provides one of the quickest options available for as low as $875. San Francisco and Cusco are separated by a distance of 4810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from San Francisco to Cusco round-trip?

Cheapflights users have booked flights from San Francisco to Cusco round-trip from $549. Other airlines that can offer you cheap pricing are LATAM Airlines, from $743, and Delta, from $763. You may be able to fly from San Francisco to Cusco for 40% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in Cusco ranges from 0.0 - 5.5 inches per month. January is typically the wettest month, when rainfall can reach 5.5 in. May is typically the driest time to visit Cusco when rainfall is around 0.0 in.

If weather is an important factor for your trip to Cusco, use this chart to help with planning. For those seeking warmer temperatures, October is the ideal time of year to visit, when temperatures reach an average of 55.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

What are the most popular airlines that fly from San Francisco to Cusco?

LATAM Airlines, Avianca and Delta are the most popular airlines when flying from San Francisco to Cusco.

Where are the most common layover locations when flying from San Francisco to Cusco?

Of the flights from San Francisco to Cusco that have layovers, most of them stop in Lima.

Where are the least popular layover locations for San Francisco to Cusco flights?

Of the flights from San Francisco to Cusco that have layovers, the fewest flights stop in Los Angeles.

What are some popular things to do or see while on a layover in Lima?

Plaza Mayor, Historic Centre of Lima, and Huaca Pucllana are currently the most popular points of interest in Lima at the moment. Plaza Mayor, Historic Centre of Lima and Huaca Pucllana are located about 5.9 mi, 5.9 mi, and 8.2 mi, respectively from Lima J Chavez Intl if you are interested in checking them out. Travelers can rent a car at Lima J Chavez Intl for an average daily rate of $39 to make sightseeing during their layover a little easier.

Most accurate provider : When it comes to deals on San Francisco-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Cusco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Francisco-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from San Francisco to Cuzco that include hotel bookings?

Yes. In addition to deals on San Francisco to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Francisco to Cuzco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Cuzco.

Can I find deals for business class flights from San Francisco to Cuzco?

Yes. Cheapflights offers flight deals from San Francisco to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$345+ Flights from San Francisco to Cusco

Q: How much does it cost to fly round-trip from San Francisco to Cusco?

Airfare is below average for this route at the moment. San Francisco to Cusco flights typically cost between $802 and $1,400 in February. The cheapest round-trip price found within the last 3 days was $688 on Avianca (Feb 13-Feb 20).

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Find flight deals from San Francisco to Cuzco

Cheapest flights from San Francisco to Cuzco
Explore the most affordable flight options available from San Francisco to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Thu 11/278:00 amSFO - CUZ

2 stops23h 26mAmerican Airlines

Sat 12/611:02 amCUZ - SFO

2 stops27h 04mAmerican Airlines

Deal found 10/26

$744

Sun 12/71:20 pmSFO - CUZ

2 stops14h 36mMultiple Airlines

Sun 12/148:47 pmCUZ - SFO

3 stops28h 03mMultiple Airlines

Deal found 10/25

$762

Thu 11/61:20 pmSFO - CUZ

3 stops28h 36mMultiple Airlines

Sun 11/96:30 pmCUZ - SFO

2 stops31h 47mMultiple Airlines

Deal found 10/25

$769

Tue 11/1111:10 pmSFO - CUZ

2 stops33h 10mMultiple Airlines

Sun 11/1610:30 pmCUZ - SFO

2 stops27h 53mMultiple Airlines

Deal found 10/25

$778

Fri 12/51:20 pmSFO - CUZ

2 stops19h 00mAvianca

Tue 2/35:10 pmCUZ - SFO

2 stops31h 40mAvianca

Deal found 10/25

$788

Tue 12/91:20 pmSFO - CUZ

3 stops28h 01mMultiple Airlines

Tue 12/1610:02 pmCUZ - SFO

2 stops16h 58mMultiple Airlines

Deal found 10/25

$855

Mon 11/248:00 amSFO - CUZ

2 stops20h 26mAmerican Airlines

Tue 12/25:02 pmCUZ - SFO

2 stops31h 00mAmerican Airlines

Deal found 10/25

$859

Mon 12/83:35 pmSFO - CUZ

2 stops17h 05mLATAM Airlines

Mon 12/229:50 pmCUZ - SFO

2 stops16h 41mLATAM Airlines

Deal found 10/24

$875

Best flights from San Francisco to Cuzco
Discover carefully curated flight deals from San Francisco to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2025.

Thu 1/81:20 pmSFO - CUZ

2 stops19h 00mAvianca

Thu 1/295:10 pmCUZ - SFO

2 stops31h 40mAvianca

Deal found 10/27

$761

Sun 12/71:20 pmSFO - CUZ

2 stops14h 36mMultiple Airlines

Sun 12/148:47 pmCUZ - SFO

3 stops28h 03mMultiple Airlines

Deal found 10/25

$762

Mon 12/83:35 pmSFO - CUZ

2 stops17h 05mLATAM Airlines

Mon 12/229:50 pmCUZ - SFO

2 stops16h 41mLATAM Airlines

Deal found 10/24

$875

Sat 12/68:02 amSFO - CUZ

2 stops33h 24mAmerican Airlines

Wed 12/1010:07 pmCUZ - SFO

2 stops39h 59mAmerican Airlines

Deal found 10/24

$885

Sun 11/239:30 pmSFO - CUZ

2 stops24h 15mDelta

Mon 12/17:50 pmCUZ - SFO

2 stops18h 39mDelta

Deal found 10/25

$974

Thu 11/61:20 pmSFO - CUZ

3 stops29h 00mMultiple Airlines

Sat 11/812:05 amCUZ - SFO

2 stops26h 12mMultiple Airlines

Deal found 10/25

$798

Sat 12/61:35 amSFO - CUZ

2 stops30h 45mAvianca

Sun 12/1412:25 pmCUZ - SFO

2 stops26h 35mAvianca

Deal found 10/25

$926

Tue 12/91:20 pmSFO - CUZ

3 stops28h 01mMultiple Airlines

Tue 12/1610:02 pmCUZ - SFO

2 stops16h 58mMultiple Airlines

Deal found 10/25

$855

Sun 11/239:30 pmSFO - CUZ

2 stops24h 15mDelta

Wed 11/269:35 pmCUZ - SFO

2 stops16h 55mDelta

Deal found 10/25

$974

Tue 11/254:10 pmSFO - CUZ

2 stops16h 10mMultiple Airlines

Tue 12/25:10 pmCUZ - SFO

2 stops27h 36mMultiple Airlines

Deal found 10/25

$883

Mon 11/241:20 pmSFO - CUZ

2 stops19h 00mMultiple Airlines

Tue 12/25:10 pmCUZ - SFO

2 stops18h 59mMultiple Airlines

Deal found 10/25

$914

Last-minute flights from San Francisco to Cuzco
Discover last-minute flight deals from San Francisco to Cuzco. Data last updated October 27, 2025 and is based on user searches.

Thu 11/61:20 pmSFO - CUZ

3 stops28h 36mMultiple Airlines

Sun 11/96:30 pmCUZ - SFO

2 stops31h 47mMultiple Airlines

Deal found 10/25

$769

Tue 11/1111:10 pmSFO - CUZ

2 stops33h 10mMultiple Airlines

Sun 11/1610:30 pmCUZ - SFO

2 stops27h 53mMultiple Airlines

Deal found 10/25

$778

Mon 11/248:00 amSFO - CUZ

2 stops20h 26mAmerican Airlines

Tue 12/25:02 pmCUZ - SFO

2 stops31h 00mAmerican Airlines

Deal found 10/25

$859

Mon 11/241:20 pmSFO - CUZ

2 stops19h 00mMultiple Airlines

Tue 12/25:10 pmCUZ - SFO

2 stops18h 59mMultiple Airlines

Deal found 10/25

$914

Tue 11/254:10 pmSFO - CUZ

2 stops16h 10mMultiple Airlines

Tue 12/25:10 pmCUZ - SFO

2 stops27h 36mMultiple Airlines

Deal found 10/25

$883

Thu 11/278:00 amSFO - CUZ

2 stops23h 26mAmerican Airlines

Sat 12/611:02 amCUZ - SFO

2 stops27h 04mAmerican Airlines

Deal found 10/26

$744

Thu 11/271:20 pmSFO - CUZ

2 stops19h 00mMultiple Airlines

Fri 12/512:05 amCUZ - SFO

2 stops27h 15mMultiple Airlines

Deal found 10/26

$887

One-way flights from San Francisco to Cuzco
Search for one-way flight options from San Francisco to Cuzco. Find affordable one-way fares based on user searches. Data last updated October 27, 2025.

Sun 11/21:20 pmSFO - CUZ

2 stops19h 00mAvianca

Deal found 10/25

$345

Mon 11/241:20 pmSFO - CUZ

2 stops19h 00mAvianca

Deal found 10/26

$363

Thu 11/2710:17 pmSFO - CUZ

3 stops30h 09mMultiple Airlines

Deal found 10/26

$365

Mon 12/111:10 pmSFO - CUZ

3 stops28h 21mMultiple Airlines

Deal found 10/24

$378

Sun 11/211:10 pmSFO - CUZ

3 stops28h 20mMultiple Airlines

Deal found 10/25

$381

Fri 11/282:54 pmSFO - CUZ

3 stops22h 37mMultiple Airlines

Deal found 10/26

$392

Mon 11/243:12 pmSFO - CUZ

3 stops49h 33mMultiple Airlines

Deal found 10/26

$394

Mon 12/158:48 amSFO - CUZ

3 stops33h 33mMultiple Airlines

Deal found 10/26

$395

Wed 11/266:00 amSFO - CUZ

2 stops21h 26mMultiple Airlines

Deal found 10/26

$396

Fri 11/2812:36 amSFO - CUZ

2 stops17h 30mMultiple Airlines

Deal found 10/26

$414

Sun 11/3011:10 pmSFO - CUZ

3 stops28h 15mMultiple Airlines

Deal found 10/26

$420

Cheap flight deals from San Francisco to Cuzco

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$688 (FlightHub)
One-way from	$345 (FlightHub)
Popular in	December
Cheapest in	February
Average price	$955

Provider with most accurate pricing for San Francisco-Cusco Velazco Astete flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Francisco-Cusco Velazco Astete flights.

Search Deals

From San Francisco to Cusco Velazco Astete

Search Deals

One-way flight from San Francisco to Cusco Velazco Astete

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($51 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Thu 1/8

1:20 pm-11:20 am

2 stops19h 00m

Cusco Velazco Astete

Thu 1/29

5:10 pm-9:50 pm

2 stops31h 40m

$761

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 12/7

1:20 pm-6:56 am

2 stops14h 36m

Cusco Velazco Astete

Sun 12/14

8:47 pm-9:50 pm

3 stops28h 03m

$762

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Thu 11/6

1:20 pm-9:20 pm

3 stops29h 00m

Cusco Velazco Astete

Sat 11/8

12:05 am-11:17 pm

2 stops26h 12m

$798

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Tue 12/9

1:20 pm-8:21 pm

3 stops28h 01m

Cusco Velazco Astete

Tue 12/16

10:02 pm-12:00 pm

2 stops16h 58m

$855

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Mon 12/8

3:35 pm-11:40 am

2 stops17h 05m

Cusco Velazco Astete

Mon 12/22

9:50 pm-11:31 am

2 stops16h 41m

$875

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Tue 11/25

4:10 pm-11:20 am

2 stops16h 10m

Cusco Velazco Astete

Tue 12/2

5:10 pm-5:46 pm

2 stops27h 36m

$883

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sat 12/6

8:02 am-8:26 pm

2 stops33h 24m

Cusco Velazco Astete

Wed 12/10

10:07 pm-11:06 am

2 stops39h 59m

$885

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Mon 11/24

1:20 pm-11:20 am

2 stops19h 00m

Cusco Velazco Astete

Tue 12/2

5:10 pm-9:09 am

2 stops18h 59m

$914

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sat 12/6

1:35 am-11:20 am

2 stops30h 45m

Cusco Velazco Astete

Sun 12/14

12:25 pm-12:00 pm

2 stops26h 35m

$926

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 11/23

9:30 pm-12:45 am

2 stops24h 15m

Cusco Velazco Astete

Mon 12/1

7:50 pm-11:29 am

2 stops18h 39m

$974

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Showing 1-10 of 22 results

Compare providers for flights from San Francisco to Cuzco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Cuzco in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Francisco-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Cusco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Francisco-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Cusco

How far ahead should I book a flight from San Francisco to Cusco?

The best time to book flights from San Francisco to Cusco is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Cusco?

Currently, December is the cheapest month in which you can book a flight from San Francisco to Cusco (average of $351). Flying from San Francisco to Cusco in January is currently the most expensive (average of $773). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to CUZ?

One of the essential ways to save on airfare from San Francisco to Cusco is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 11% on airfare.

What is the cheapest day to fly from San Francisco to Cusco?

Travelers seeking maximum savings on their San Francisco to Cusco flight should consider departing on Sunday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from San Francisco to Cusco?

Reviews of airlines servicing Cuzco

Read through reviews of airlines operating flights from San Francisco to Cusco, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

7.9

Good

7,994 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,872 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

11,031 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca

6.6

Okay

2,464 reviews

Delta

7.9

Good

7,994 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

How long is the flight from San Francisco to Cusco?
A quick flight from San Francisco to Cusco can take about 17h 05m. Avianca provides one of the quickest options available for as low as $875. San Francisco and Cusco are separated by a distance of 4810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from San Francisco to Cusco round-trip?
Cheapflights users have booked flights from San Francisco to Cusco round-trip from $549. Other airlines that can offer you cheap pricing are LATAM Airlines, from $743, and Delta, from $763. You may be able to fly from San Francisco to Cusco for 40% less than the average price by searching for these airlines.
Where are the most common layover locations when flying from San Francisco to Cusco?
Of the flights from San Francisco to Cusco that have layovers, most of them stop in Lima.
What are some popular things to do or see while on a layover in Lima?
Plaza Mayor, Historic Centre of Lima, and Huaca Pucllana are currently the most popular points of interest in Lima at the moment. Plaza Mayor, Historic Centre of Lima and Huaca Pucllana are located about 5.9 mi, 5.9 mi, and 8.2 mi, respectively from Lima J Chavez Intl if you are interested in checking them out. Travelers can rent a car at Lima J Chavez Intl for an average daily rate of $39 to make sightseeing during their layover a little easier.
Where are the least popular layover locations for San Francisco to Cusco flights?
Of the flights from San Francisco to Cusco that have layovers, the fewest flights stop in Los Angeles.
Can I find deals for flights from San Francisco to Cuzco that include hotel bookings?
Yes. In addition to deals on San Francisco to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Cuzco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Cuzco.
Can I find deals for business class flights from San Francisco to Cuzco?
Yes. Cheapflights offers flight deals from San Francisco to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Cusco?
Currently, December is the cheapest month in which you can book a flight from San Francisco to Cusco (average of $351). Flying from San Francisco to Cusco in January is currently the most expensive (average of $773). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from San Francisco to Cuzco

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$549	Average$721	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$743	Average$1,018	FlexibilityNo cancel fee	On-time81%
Delta	Cheapest$763	Average$808	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$911	Average$1,202	FlexibilityNo cancel fee	On-time71%

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$345+ Cheap flights from San Francisco (SFO) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Cuzco with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Find flight deals from San Francisco to Cuzco

Cheapest flights from San Francisco to CuzcoExplore the most affordable flight options available from San Francisco to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Explore the most affordable flight options available from San Francisco to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Cheap flight deals from San Francisco to Cuzco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Cusco that are best for you.

Compare providers for flights from San Francisco to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Cuzco in October.

Best time to book a flight from San Francisco to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Cusco

How far ahead should I book a flight from San Francisco to Cusco?

What is the cheapest month to book a flight from San Francisco to Cusco?

What is the cheapest time of day to fly from SFO to CUZ?

What is the cheapest day to fly from San Francisco to Cusco?

How much does it cost to fly round-trip from San Francisco to Cusco?

Reviews of airlines servicing Cuzco

Read through reviews of airlines operating flights from San Francisco to Cusco, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from San Francisco to Cusco?

What are the cheapest airlines flying from San Francisco to Cusco round-trip?

Where are the most common layover locations when flying from San Francisco to Cusco?

What are some popular things to do or see while on a layover in Lima?

Where are the least popular layover locations for San Francisco to Cusco flights?

Can I find deals for flights from San Francisco to Cuzco that include hotel bookings?

How can I find direct flights from San Francisco to Cuzco?

Can I find deals for business class flights from San Francisco to Cuzco?

What is the cheapest month to book a flight from San Francisco to Cusco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from San Francisco to Cuzco

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Cheapest flights from San Francisco to Cuzco
Explore the most affordable flight options available from San Francisco to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.