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Cuzco

$345+ Cheap flights from San Francisco (SFO) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CUZ
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from San Francisco to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$693
(FlightHub)

One-way from

$345
(Avianca)

Popular in

December

Cheapest in

February

Average price

$815
From San Francisco to Cusco Velazco Astete
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One-way flight from San Francisco to Cusco Velazco Astete
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Highest demand for flights based on searches. 8% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco to Cuzco

Cheapest flights from San Francisco to Cuzco
Explore the most affordable flight options available from San Francisco to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Gotogate deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/92:20 pmSFO - CUZ
2 stops18h 40mAvianca
Wed 10/2212:15 pmCUZ - SFO
2 stops26h 20mAvianca
Deal found 9/9$699
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:33 pmSFO - CUZ
2 stops17h 52mLATAM Airlines
Tue 2/37:50 pmCUZ - SFO
2 stops19h 11mLATAM Airlines
Deal found 9/10$733
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/252:20 pmSFO - CUZ
3 stops27h 56mMultiple Airlines
Sat 11/19:42 pmCUZ - SFO
2 stops17h 18mMultiple Airlines
Deal found 9/9$734
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/252:35 amSFO - CUZ
3 stops26h 21mMultiple Airlines
Sun 11/27:02 amCUZ - SFO
3 stops31h 58mMultiple Airlines
Deal found 9/11$738
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:30 pmSFO - CUZ
2 stops17h 05mLATAM Airlines
Sun 10/1911:55 pmCUZ - SFO
2 stops26h 10mLATAM Airlines
Deal found 9/9$753
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:20 pmSFO - CUZ
3 stops29h 04mMultiple Airlines
Sat 10/257:12 amCUZ - SFO
3 stops31h 48mMultiple Airlines
Deal found 9/9$754
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:10 amSFO - CUZ
2 stops33h 10mAvianca
Sun 11/212:25 pmCUZ - SFO
2 stops26h 35mAvianca
Deal found 9/11$759

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from San Francisco to Cusco that are best for you.

Fly from

San Francisco

Fly to

Cuzco

Route

Depart

Return

Price

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 10/26

2:20 pm-11:20 am

2 stops19h 00m

Cusco Velazco Astete

Sun 11/2

12:25 pm-12:00 pm

2 stops26h 35m

$699

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Thu 10/9

2:20 pm-11:00 am

2 stops18h 40m

Cusco Velazco Astete

Wed 10/22

12:15 pm-12:35 pm

2 stops26h 20m

$699

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Fri 12/5

12:33 pm-11:10 am

2 stops19h 37m

Cusco Velazco Astete

Tue 2/3

7:35 am-10:11 pm

2 stops17h 36m

$733

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 10/26

2:20 pm-8:50 pm

3 stops28h 30m

Cusco Velazco Astete

Sat 11/1

12:05 am-1:00 pm

2 stops14h 55m

$747

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Thu 10/9

3:30 pm-10:35 am

2 stops17h 05m

Cusco Velazco Astete

Sun 10/19

11:55 pm-12:05 am

2 stops26h 10m

$753

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Tue 10/14

12:05 am-6:14 am

3 stops28h 09m

Cusco Velazco Astete

Sat 10/25

7:12 am-1:00 pm

3 stops31h 48m

$763

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sat 11/1

1:45 pm-5:00 pm

2 stops25h 15m

Cusco Velazco Astete

Sat 11/8

7:35 am-9:57 pm

2 stops17h 22m

$773

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 9/21

12:05 am-11:00 am

2 stops32h 55m

Cusco Velazco Astete

Wed 10/8

12:15 pm-12:35 pm

2 stops26h 20m

$787

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Thu 9/18

2:20 pm-11:00 am

2 stops18h 40m

$345

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 10/5

2:20 pm-11:00 am

2 stops18h 40m

$345

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/8

Showing 1-10 of 12 results
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Best time to book a flight from San Francisco to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Cusco

How far ahead should I book a flight from San Francisco to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Cuzco. Price data was last updated on August 29, 2025.

The best time to book flights from San Francisco to Cusco is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Cusco?

Currently, February is the cheapest month in which you can book a flight from San Francisco to Cusco (average of $789). Flying from San Francisco to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to CUZ?

Find hourly flight availability from San Francisco to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from San Francisco to Cusco is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 12% on airfare.

What is the cheapest day to fly from San Francisco to Cusco?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Cuzco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Cusco flight should consider departing on Sunday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from San Francisco to Cusco?

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from San Francisco to Cusco, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,436 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Cusco?

    A quick flight from San Francisco to Cusco can take about 19h. Avianca provides one of the quickest options available for as low as $699. San Francisco and Cusco are separated by a distance of 4810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Francisco to Cusco round-trip?

    Cheapflights users have booked flights from San Francisco to Cusco round-trip from $571. Other airlines that can offer you cheap pricing are Delta, from $723, and LATAM Airlines, from $726. You may be able to fly from San Francisco to Cusco for 38% less than the average price by searching for these airlines.

  • Where are the most common layover locations when flying from San Francisco to Cusco?

    Of the flights from San Francisco to Cusco that have layovers, most of them stop in Lima.

  • What are some popular things to do or see while on a layover in Lima?

    Plaza Mayor, Historic Centre of Lima, and Huaca Pucllana are currently the most popular points of interest in Lima at the moment. Plaza Mayor, Historic Centre of Lima and Huaca Pucllana are located about 5.9 mi, 5.9 mi, and 8.2 mi, respectively from Lima J Chavez Intl if you are interested in checking them out. Travelers can rent a car at Lima J Chavez Intl for an average daily rate of $43 to make sightseeing during their layover a little easier.

  • Where are the least popular layover locations for San Francisco to Cusco flights?

    Of the flights from San Francisco to Cusco that have layovers, the fewest flights stop in Los Angeles.

  • Can I find deals for flights from San Francisco to Cuzco that include hotel bookings?

    Yes. In addition to deals on San Francisco to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Cuzco.

  • Can I find deals for business class flights from San Francisco to Cuzco?

    Yes. Cheapflights offers flight deals from San Francisco to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Cusco?

    Currently, February is the cheapest month in which you can book a flight from San Francisco to Cusco (average of $789). Flying from San Francisco to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from San Francisco to Cuzco

Discover the top 4 airlines that operate flights from San Francisco to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$571Average$717FlexibilityNo cancel feeOn-time71%
DeltaCheapest$723Average$886FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$726Average$1,005FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$913Average$1,202FlexibilityNo cancel feeOn-time71%

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