HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cuzco

$381+ Cheap flights from Durham, NC to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CUZ
Dec 21 — Dec 281
Sun 12/21
Sun 12/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to Cuzco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Durham to Cuzco

Keep the following information in mind while searching for Durham to Cuzco flight deals. Data was last updated November 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$717
(American Airlines)

One-way from

$425
(Ovago)

Popular in

December

Cheapest in

September

Average price

$720
Provider with most accurate pricing for Raleigh-Durham-Cusco Velazco Astete flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Cusco Velazco Astete flights.
Search Deals
From Durham to Cusco Velazco Astete
Search Deals
One-way flight from Durham to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($252 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($95 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Durham to Cuzco

Cheapest flights from Durham to Cuzco
Explore the most affordable flight options available from Durham to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2025.

This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/228:05 amRDU - CUZ
2 stops16h 35mDelta
Mon 12/89:05 pmCUZ - RDU
2 stops23h 20mDelta
Deal found 11/19$802
This Mytrip deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:30 amRDU - CUZ
3 stops30h 25mMultiple Airlines
Wed 1/1411:07 amCUZ - RDU
2 stops27h 06mMultiple Airlines
Deal found 11/21$987
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:32 pmRDU - CUZ
2 stops19h 14mAmerican Airlines
Wed 1/148:57 pmCUZ - RDU
2 stops14h 04mAmerican Airlines
Deal found 11/21$1,024
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:00 amRDU - CUZ
2 stops27h 20mMultiple Airlines
Sun 1/116:30 pmCUZ - RDU
2 stops19h 43mMultiple Airlines
Deal found 11/19$1,260
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2212:15 pmRDU - CUZ
3 stops23h 05mMultiple Airlines
Mon 12/85:10 pmCUZ - RDU
2 stops20h 29mMultiple Airlines
Deal found 11/19$1,318
This Air Canada deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:25 pmRDU - CUZ
2 stops21h 55mMultiple Airlines
Thu 11/275:10 pmCUZ - RDU
2 stops44h 58mMultiple Airlines
Deal found 11/19$1,388
This Expedia deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:15 amRDU - CUZ
2 stops24h 10mLATAM Airlines
Tue 1/1312:05 amCUZ - RDU
2 stops22h 37mLATAM Airlines
Deal found 11/21$1,438

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Durham to Cusco that are best for you.

Fly from

Durham

Fly to

Cuzco

Route

Depart

Return

Price

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Wed 4/1

12:28 pm-4:09 pm

2 stops28h 41m

Cusco Velazco Astete

Mon 4/6

6:57 am-10:43 am

2 stops26h 46m

$717

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Thu 1/22

11:51 am-6:26 am

2 stops18h 35m

Cusco Velazco Astete

Mon 1/26

8:57 pm-4:39 pm

2 stops19h 42m

$717

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Tue 3/31

12:28 pm-6:24 am

2 stops18h 56m

Cusco Velazco Astete

Mon 4/6

11:57 am-10:43 am

2 stops21h 46m

$717

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Thu 4/30

6:10 pm-7:19 am

2 stops14h 09m

Cusco Velazco Astete

Thu 5/14

3:57 pm-10:43 am

2 stops17h 46m

$717

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Mon 3/30

6:32 pm-7:26 am

2 stops13h 54m

Cusco Velazco Astete

Tue 4/7

3:47 pm-7:37 pm

2 stops26h 50m

$717

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Fri 5/8

7:40 pm-7:24 am

2 stops12h 44m

Cusco Velazco Astete

Tue 5/19

4:42 pm-9:22 am

2 stops15h 40m

$717

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Wed 4/1

7:47 pm-4:44 pm

2 stops21h 57m

Cusco Velazco Astete

Wed 4/8

11:12 am-9:45 pm

2 stops33h 33m

$726

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Mon 3/30

7:47 pm-7:26 am

2 stops12h 39m

Cusco Velazco Astete

Wed 4/8

8:02 am-9:45 pm

2 stops36h 43m

$726

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Wed 12/24

5:50 pm-7:15 pm

3 stops49h 25m

$381

RaleighCusco

RDU - CUZ

RDUCUZ

Raleigh-Durham

Wed 11/26

2:12 pm-5:20 pm

2 stops27h 08m

$425

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 11 results
1
2

Best time to book a flight from Durham to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Cusco

What is the cheapest month to book a flight from Durham to Cusco?

Currently, August is the cheapest month in which you can book a flight from Durham to Cusco (average of $563). Flying from Durham to Cusco in December is currently the most expensive (average of $987). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to CUZ?

Find hourly flight availability from Durham to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 17% on flights from Durham to Cusco by exploring options for tickets in the evening.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated November 21, 2025.
Read through reviews of airlines operating flights from Durham to Cusco, such as LATAM Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,884 reviews

Comfort

7.3

Entertainment

7.0

Food

6.7

Crew

8.0

Boarding

7.6

Overall

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,884 reviews
LATAM Airlines
7.5
Good
1,884 reviews

Comfort

7.3

Entertainment

7.0

Food

6.7

Crew

8.0

Boarding

7.6

Overall

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
American Airlines
7.2
Good
11,047 reviews
LATAM Airlines
7.5
Good
1,884 reviews

Comfort

7.3

Entertainment

7.0

Food

6.7

Crew

8.0

Boarding

7.6

Overall

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Durham to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cusco from Durham?

    Located just 1.7 mi from the city center, Cusco Velazco Astete is the airport most travelers will use when flying to Cusco from Durham. Booking flights from Durham to Velazco Astete (CUZ) should be relatively easy as there are 0 daily inbound flights from Durham from 2 different airlines.

  • How long is the flight from Durham to Cusco?

    A quick flight from Durham to Cusco can take about 28h 41m. American Airlines provides one of the quickest options available for as low as $717. Durham and Cusco are separated by a distance of 3441 mi.

  • Can I find deals for flights from Durham to Cuzco that include hotel bookings?

    Yes. In addition to deals on Durham to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Cuzco.

  • Can I find deals for business class flights from Durham to Cuzco?

    Yes. Cheapflights offers flight deals from Durham to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Cusco?

    Currently, August is the cheapest month in which you can book a flight from Durham to Cusco (average of $563). Flying from Durham to Cusco in December is currently the most expensive (average of $987). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Durham to Cuzco

Discover the top 2 airlines that operate flights from Durham to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$563Average$714FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$659Average$1,079FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.