$210+ Cheap flights from Durham, NC to Cusco (CUZ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CUZ
Mar 14 — Mar 211
1 adult, Economy
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Cheapest flights from Durham to CuzcoExplore the most affordable flight options available from Durham to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from Durham to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:51 pm
RDU
- CUZ
2 stops18h 29m
Avianca
Mon 11/165:10 pm
CUZ
- RDU
2 stops18h 45m
Avianca
Deal found 2/11![Avianca logo]()
$584
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:27 am
RDU
- CUZ
2 stops19h 58m
American Airlines
Thu 5/2811:25 am
CUZ
- RDU
2 stops28h 25m
American Airlines
Deal found 2/10![American Airlines logo]()
$738
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:36 pm
RDU
- CUZ
3 stops55h 09m
LATAM Airlines
Fri 3/135:00 am
CUZ
- RDU
2 stops17h 10m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$746
This BusinessClass deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:20 am
RDU
- CUZ
2 stops27h 25m
LATAM Airlines
Mon 6/229:30 pm
CUZ
- RDU
3 stops34h 20m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$747
This KAYAK deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:35 am
RDU
- CUZ
3 stops19h 05m
LATAM Airlines
Thu 6/188:25 am
CUZ
- RDU
2 stops15h 01m
LATAM Airlines
Deal found 2/12![LATAM Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:04 am
RDU
- CUZ
2 stops25h 21m
Delta
Tue 5/2610:05 am
CUZ
- RDU
2 stops27h 35m
Delta
Deal found 2/10![Delta logo]()
$770
This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:18 pm
RDU
- CUZ
2 stops20h 22m
LATAM Airlines
Wed 3/48:10 pm
CUZ
- RDU
2 stops20h 37m
LATAM Airlines
Deal found 2/11![LATAM Airlines logo]()
$781
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:59 pm
RDU
- CUZ
3 stops55h 41m
LATAM Airlines
Sat 5/305:00 am
CUZ
- RDU
3 stops18h 08m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$790
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 am
RDU
- CUZ
2 stops24h 55m
American Airlines
Mon 5/2510:30 pm
CUZ
- RDU
2 stops24h 29m
American Airlines
Deal found 2/10![American Airlines logo]()
$821
Best flights from Durham to CuzcoDiscover carefully curated flight deals from Durham to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from Durham to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This LATAM Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:54 pm
RDU
- CUZ
2 stops15h 06m
LATAM Airlines
Wed 3/47:50 pm
CUZ
- RDU
2 stops14h 05m
LATAM Airlines
Deal found 2/8![LATAM Airlines logo]()
$738
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 am
RDU
- CUZ
2 stops24h 55m
American Airlines
Tue 5/2610:50 am
CUZ
- RDU
2 stops29h 00m
American Airlines
Deal found 2/10![American Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:04 am
RDU
- CUZ
2 stops41h 36m
Delta
Wed 5/277:30 am
CUZ
- RDU
2 stops27h 20m
Delta
Deal found 2/10![Delta logo]()
$747
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:27 am
RDU
- CUZ
2 stops19h 58m
American Airlines
Wed 5/2711:55 am
CUZ
- RDU
2 stops27h 55m
American Airlines
Deal found 2/10![American Airlines logo]()
$738
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:36 pm
RDU
- CUZ
3 stops55h 09m
LATAM Airlines
Fri 3/135:00 am
CUZ
- RDU
2 stops17h 10m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$746
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:04 am
RDU
- CUZ
2 stops41h 36m
Delta
Thu 5/285:00 am
CUZ
- RDU
2 stops14h 45m
Delta
Deal found 2/10![Delta logo]()
$747
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:20 am
RDU
- CUZ
2 stops27h 25m
LATAM Airlines
Mon 6/225:00 am
CUZ
- RDU
3 stops26h 50m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$747
This KAYAK deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:35 am
RDU
- CUZ
3 stops19h 05m
LATAM Airlines
Thu 6/188:25 am
CUZ
- RDU
2 stops15h 01m
LATAM Airlines
Deal found 2/12![LATAM Airlines logo]()
$760
Last-minute flights from Durham to CuzcoDiscover last-minute flight deals from Durham to Cuzco. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to Cuzco. Data last updated February 12, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:54 pm
RDU
- CUZ
2 stops15h 06m
LATAM Airlines
Wed 3/47:50 pm
CUZ
- RDU
2 stops14h 05m
LATAM Airlines
Deal found 2/8![LATAM Airlines logo]()
$738
This Gurufare deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:36 pm
RDU
- CUZ
3 stops55h 09m
LATAM Airlines
Fri 3/135:00 am
CUZ
- RDU
2 stops17h 10m
LATAM Airlines
Deal found 2/9![LATAM Airlines logo]()
$746
This Mytrip deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:30 am
RDU
- CUZ
3 stops26h 50m
Multiple Airlines
Fri 3/1311:02 am
CUZ
- RDU
3 stops29h 27m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$922
This Gurufare deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:46 pm
RDU
- CUZ
2 stops21h 14m
LATAM Airlines
Fri 4/38:25 am
CUZ
- RDU
2 stops14h 56m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$878
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:05 am
RDU
- CUZ
2 stops24h 35m
LATAM Airlines
Thu 4/25:00 am
CUZ
- RDU
3 stops27h 06m
LATAM Airlines
Deal found 2/10![LATAM Airlines logo]()
$1,047
This BusinessClass deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:25 pm
RDU
- CUZ
3 stops31h 15m
LATAM Airlines
Sun 4/57:50 pm
CUZ
- RDU
2 stops23h 06m
LATAM Airlines
Deal found 2/11![LATAM Airlines logo]()
$1,012
This CheapOair deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:53 pm
RDU
- CUZ
3 stops36h 42m
Multiple Airlines
Sun 4/58:15 pm
CUZ
- RDU
3 stops20h 14m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$1,550
One-way flights from Durham to CuzcoSearch for one-way flight options from Durham to Cuzco. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from Durham to Cuzco. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Trip.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:17 pm
RDU
- CUZ
2 stops33h 08m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:07 pm
RDU
- CUZ
3 stops39h 03m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:32 pm
RDU
- CUZ
2 stops14h 38m
American Airlines
Deal found 2/11![American Airlines logo]()
$402
Find flight deals from Durham to Cuzco
Keep the following information in mind while searching for Durham to Cuzco flight deals. Data was last updated February 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $738 (American Airlines) |
One-way from | $210 (Trip.com) |
Popular in | December |
Cheapest in | March |
Average price | $886 |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Durham to Cusco that are best for you.
Fly from
Durham
Fly to
Cuzco
Route
Depart
Return
Price
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Mon 3/2
5:54 pm-9:00 am
2 stops15h 06m
Cusco Velazco Astete
Wed 3/4
7:50 pm-9:55 am
2 stops14h 05m
$738
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Wed 5/20
6:30 am-6:25 am
2 stops24h 55m
Cusco Velazco Astete
Tue 5/26
10:50 am-4:50 pm
2 stops29h 00m
$738
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Wed 5/20
11:27 am-6:25 am
2 stops19h 58m
Cusco Velazco Astete
Wed 5/27
11:55 am-4:50 pm
2 stops27h 55m
$738
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Sun 3/8
6:36 pm-12:45 am
3 stops55h 09m
Cusco Velazco Astete
Fri 3/13
5:00 am-11:10 pm
2 stops17h 10m
$746
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Sun 5/24
8:04 am-12:40 am
2 stops41h 36m
Cusco Velazco Astete
Wed 5/27
7:30 am-11:50 am
2 stops27h 20m
$747
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Sun 5/24
8:04 am-12:40 am
2 stops41h 36m
Cusco Velazco Astete
Thu 5/28
5:00 am-8:45 pm
2 stops14h 45m
$747
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Thu 6/18
8:20 am-10:45 am
2 stops27h 25m
Cusco Velazco Astete
Mon 6/22
5:00 am-8:50 am
3 stops26h 50m
$747
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Tue 6/9
6:35 am-12:40 am
3 stops19h 05m
Cusco Velazco Astete
Thu 6/18
8:25 am-12:26 am
2 stops15h 01m
$760
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Sun 3/15
10:17 pm-6:25 am
2 stops33h 08m
$210
RaleighCusco
RDU - CUZ
RDUCUZ
Raleigh-Durham
Wed 4/29
4:07 pm-6:10 am
3 stops39h 03m
$306
Showing 1-10 of 11 results
Best time to book a flight from Durham to Cuzco
Have a flexible travel schedule? Discover the best time to fly to Cuzco from Durham with our price prediction graph.
RDU-CUZ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to Cusco
DU8-CUZ
RDU-CUZ
What is the cheapest month to book a flight from Durham to Cusco?
Currently, October is the cheapest month in which you can book a flight from Durham to Cusco (average of $563). Flying from Durham to Cusco in December is currently the most expensive (average of $1,890). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Cuzco
Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated February 12, 2026.
Read through reviews of airlines operating flights from Durham to Cusco, such as LATAM Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Comfort
7.3
Food
6.7
Crew
8.0
Overall
7.5
Entertainment
7.0
Reviews
1 / 20
8.0
ExcellentLUIS JOSE,Oct 2025
LIM - AEP
Boarding
7.5
Comfort
7.3
Food
6.7
Crew
8.0
Overall
7.5
Entertainment
7.0
Reviews
1 / 20
8.0
ExcellentLUIS JOSE,Oct 2025
LIM - AEP
Boarding
7.5
Comfort
7.3
Food
6.7
Crew
8.0
Overall
7.5
Entertainment
7.0
Reviews
1 / 20
8.0
ExcellentLUIS JOSE,Oct 2025
LIM - AEP
Related info for your journey
Find useful and relevant information for your journey from Durham to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Other flights to Cuzco
Explore flights to Cuzco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 12, 2026.
Search flights from Durham to Cuzco by cabin class
Find flights from Durham to Cuzco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and Cuzco flights
Browse other Durham and Cuzco flight options. Last updated on February 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Durham to Cuzco flights
Consider these flights traveling from Durham to Cuzco.
Top 2 airlines flying from Durham to Cuzco
Discover the top 2 airlines that operate flights from Durham to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$563 | Average$776 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$659 | Average$903 | FlexibilityNo cancel fee | On-time71% |