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$323+ Cheap flights from Denver (DEN) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CUZ
Nov 1 — Nov 81
Sat 11/1
Sat 11/8
1 adult, Economy
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Cheap flight deals from Denver to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$660
(FlightHub)

One-way from

$358
(American Airlines)

Popular in

July

Cheapest in

February

Average price

$807
Provider with most accurate pricing for Denver Intl-Cusco Velazco Astete flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Cusco Velazco Astete flights.
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From Denver Intl to Cusco Velazco Astete
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One-way flight from Denver Intl to Cusco Velazco Astete
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Highest demand for flights based on searches. 17% potential increase in price ($184 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Denver to Cuzco

Cheapest flights from Denver to Cuzco
Explore the most affordable flight options available from Denver to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2025.

This FlightHub deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/153:14 pmDEN - CUZ
2 stops16h 11mLATAM Airlines
Tue 11/257:30 amCUZ - DEN
2 stops17h 29mLATAM Airlines
Deal found 9/30$660
This LATAM Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:05 amDEN - CUZ
2 stops23h 35mLATAM Airlines
Wed 10/297:35 amCUZ - DEN
2 stops26h 46mLATAM Airlines
Deal found 9/29$673
This LATAM Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:05 amDEN - CUZ
2 stops21h 40mLATAM Airlines
Sat 11/225:05 amCUZ - DEN
2 stops19h 54mLATAM Airlines
Deal found 9/30$677
This LATAM Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/306:25 amDEN - CUZ
2 stops22h 30mLATAM Airlines
Sat 12/611:20 pmCUZ - DEN
2 stops27h 04mLATAM Airlines
Deal found 9/30$699
This FlightHub deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:15 amDEN - CUZ
2 stops24h 10mLATAM Airlines
Sun 11/165:05 amCUZ - DEN
2 stops21h 08mLATAM Airlines
Deal found 10/1$742
This SmartFares deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:38 pmDEN - CUZ
2 stops39h 37mLATAM Airlines
Thu 11/2012:05 amCUZ - DEN
2 stops26h 08mLATAM Airlines
Deal found 9/29$752
This LATAM Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/27:05 amDEN - CUZ
2 stops15h 40mLATAM Airlines
Sun 11/2310:45 pmCUZ - DEN
2 stops26h 14mLATAM Airlines
Deal found 9/30$758

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Denver to Cusco that are best for you.

Fly from

Denver

Fly to

Cuzco

Route

Depart

Return

Price

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Sat 11/15

3:14 pm-9:25 am

2 stops16h 11m

Cusco Velazco Astete

Tue 11/25

7:30 am-10:59 pm

2 stops17h 29m

$660

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Tue 10/21

7:05 am-6:35 am

2 stops22h 30m

Cusco Velazco Astete

Tue 10/28

12:05 am-9:21 am

2 stops34h 16m

$673

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Tue 11/11

3:14 pm-12:35 pm

2 stops19h 21m

Cusco Velazco Astete

Fri 11/21

12:05 am-10:59 pm

2 stops24h 54m

$673

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Sun 11/30

6:25 am-6:15 am

2 stops21h 50m

Cusco Velazco Astete

Sat 12/6

11:20 pm-12:24 am

2 stops27h 04m

$699

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Sun 10/19

10:46 pm-5:55 am

2 stops30h 09m

$323

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Thu 12/11

8:30 am-6:26 am

2 stops19h 56m

$358

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Wed 12/10

12:51 am-8:26 pm

3 stops41h 35m

$360

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Thu 10/16

1:23 pm-5:40 pm

2 stops27h 17m

$369

DenverCusco

DEN - CUZ

DENCUZ

Denver Intl

Mon 10/20

7:05 am-5:55 am

2 stops21h 50m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/29

Compare providers for flights from Denver to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Cuzco in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Cusco

How far ahead should I book a flight from Denver to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Cuzco. Price data was last updated on September 26, 2025.

To ensure you get the cheapest price possible for a flight from Denver to Cusco, you should look to book at least 84 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Denver to Cusco?

Currently, February is the cheapest month in which you can book a flight from Denver to Cusco (average of $789). Flying from Denver to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to CUZ?

Find hourly flight availability from Denver to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 2, 2025.

It’s optimal to fly from Denver to Cusco in the evening. By choosing this option you can save up to 44% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated October 2, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Denver to Cusco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,858 reviews
Delta
8.0
Very good
7,961 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
11,030 reviews
Delta
8.0
Very good
7,961 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Cusco?

    For as low as $660, LATAM Airlines can have you in Cusco from Denver in 16h 11m. There are 4243 mi between Denver and Cusco.

  • What are the cheapest airlines flying from Denver to Cusco round-trip?

    According to our current data, Delta ($535), LATAM Airlines ($592), and American Airlines ($675) offers the cheapest pricing from Denver to Cusco. Delta is currently priced 38% below the average price you’ll pay for this route.

  • Where are the most common layover locations when flying from Denver to Cusco?

    The most popular layover on flights from Denver to Cusco is Lima.

  • What are some popular things to do or see while on a layover in Lima?

    Plaza Mayor, Historic Centre of Lima, and Huaca Pucllana are the most popular attractions in Lima if you're in need of something to do during your layover. Plaza Mayor, Historic Centre of Lima, and Huaca Pucllana can be visited by traveling about 5.9 mi, 5.9 mi, and 8.2 mi respectively from Lima J Chavez Intl. Travelers can rent a car at Lima J Chavez Intl for an average daily rate of $26 to make sightseeing during their layover a little easier.

  • Where are the least popular layover locations for Denver to Cusco flights?

    Denver to Cusco flights have a layover in Atlanta the least frequently.

  • Can I find deals for flights from Denver to Cuzco that include hotel bookings?

    Yes. In addition to deals on Denver to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Cuzco.

  • Can I find deals for business class flights from Denver to Cuzco?

    Yes. Cheapflights offers flight deals from Denver to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Cusco?

    Currently, February is the cheapest month in which you can book a flight from Denver to Cusco (average of $789). Flying from Denver to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Denver to Cuzco

Discover the top 3 airlines that operate flights from Denver to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$535Average$814FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$592Average$904FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$675Average$936FlexibilityNo cancel feeOn-time71%

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