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Cuzco

$760+ Cheap flights from Charleston (CHS) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Mar 17 — Mar 241
Tue 3/17
Tue 3/24
1 adult, Economy
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Cheap flight deals from Charleston to Cuzco

Cheapest flights from Charleston to Cuzco
Explore the most affordable flight options available from Charleston to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 15, 2026.

This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:07 am
CHS
-
CUZ
2 stops23h 18m
Multiple Airlines
Sun 3/227:02 am
CUZ
-
CHS
3 stops38h 11m
Multiple Airlines
Deal found 2/13$760
This KAYAK deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:03 am
CHS
-
CUZ
2 stops25h 17m
Avianca
Tue 7/215:10 pm
CUZ
-
CHS
2 stops19h 52m
Avianca
Deal found 2/13$865
This KAYAK deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:10 pm
CHS
-
CUZ
2 stops11h 16m
GOL
Thu 9/2411:02 am
CUZ
-
CHS
2 stops22h 18m
GOL
Deal found 2/13$869
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:39 am
CHS
-
CUZ
2 stops13h 42m
American Airlines
Thu 9/2412:02 pm
CUZ
-
CHS
2 stops21h 18m
American Airlines
Deal found 2/13$890
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
CHS
-
CUZ
2 stops26h 02m
American Airlines
Sun 6/710:05 pm
CUZ
-
CHS
2 stops20h 23m
American Airlines
Deal found 2/11$916
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
CHS
-
CUZ
2 stops26h 02m
American Airlines
Fri 6/510:25 pm
CUZ
-
CHS
2 stops24h 30m
American Airlines
Deal found 2/11$942
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
CHS
-
CUZ
2 stops26h 02m
GOL
Sat 6/69:40 pm
CUZ
-
CHS
2 stops25h 15m
GOL
Deal found 2/11$945
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
CHS
-
CUZ
2 stops24h 02m
American Airlines
Sun 6/78:50 pm
CUZ
-
CHS
2 stops21h 38m
American Airlines
Deal found 2/12$950
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
CHS
-
CUZ
2 stops12h 12m
GOL
Sun 6/79:00 pm
CUZ
-
CHS
2 stops21h 28m
GOL
Deal found 2/11$959
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
CHS
-
CUZ
2 stops15h 47m
American Airlines
Fri 6/510:25 pm
CUZ
-
CHS
2 stops20h 03m
American Airlines
Deal found 2/11$976
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
CHS
-
CUZ
2 stops12h 12m
GOL
Sat 6/67:45 pm
CUZ
-
CHS
2 stops22h 43m
GOL
Deal found 2/11$1,016

Find flight deals from Charleston to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 15, 2026.

Round-trip from

$760
(Mytrip)
From Charleston to Cusco Velazco Astete
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 15, 2026.
Use the filters below to find and compare flights from Charleston to Cusco that are best for you.

Fly from

Charleston

Fly to

Cuzco

Route

Depart

Return

Price

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 3/15

8:07 am-6:25 am

2 stops23h 18m

Cusco Velazco Astete

Sun 3/22

7:02 am-10:13 pm

3 stops38h 11m

$760

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Tue 7/14

11:03 am-11:20 am

2 stops25h 17m

Cusco Velazco Astete

Tue 7/21

5:10 pm-2:02 pm

2 stops19h 52m

$865

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 5/24

8:08 pm-9:05 pm

2 stops25h 57m

Cusco Velazco Astete

Sun 6/7

10:05 pm-7:28 pm

2 stops20h 23m

$916

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 5/23

8:08 pm-9:10 pm

2 stops26h 02m

Cusco Velazco Astete

Fri 6/5

10:25 pm-11:55 pm

2 stops24h 30m

$942

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 5/24

8:08 pm-9:05 pm

2 stops25h 57m

Cusco Velazco Astete

Fri 6/5

10:48 am-7:28 pm

2 stops31h 40m

$942

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 5/23

8:08 pm-9:10 pm

2 stops26h 02m

Cusco Velazco Astete

Sat 6/6

9:40 pm-11:55 pm

2 stops25h 15m

$945

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 5/22

8:08 pm-7:10 pm

2 stops24h 02m

Cusco Velazco Astete

Sun 6/7

8:50 pm-7:28 pm

2 stops21h 38m

$950

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 5/22

8:08 pm-7:20 am

2 stops12h 12m

Cusco Velazco Astete

Sun 6/7

9:00 pm-7:28 pm

2 stops21h 28m

$959

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 5/23

8:08 pm-8:20 pm

2 stops25h 12m

Cusco Velazco Astete

Sat 6/6

9:40 pm-11:55 pm

2 stops25h 15m

$976

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 5/22

8:08 pm-10:55 am

2 stops15h 47m

Cusco Velazco Astete

Fri 6/5

10:25 pm-7:28 pm

2 stops20h 03m

$976

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/13

Best time to book a flight from Charleston to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Cusco?

    Airlines like Avianca and American Airlines fly from Charleston to Cusco in about 25h 17m. The time it takes to get you to your destination can typically vary by up to 40m. Charleston and Cusco are separated by a distance of 3250 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Charleston to Cuzco that include hotel bookings?

    Yes. In addition to deals on Charleston to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Cuzco.

  • Can I find deals for business class flights from Charleston to Cuzco?

    Yes. Cheapflights offers flight deals from Charleston to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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