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$865+ Cheap flights from Charleston (CHS) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Charleston to Cuzco

Cheapest flights from Charleston to Cuzco
Explore the most affordable flight options available from Charleston to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:00 am
CHS
-
CUZ
3 stops39h 05m
Multiple Airlines
Sun 5/104:50 pm
CUZ
-
CHS
3 stops20h 50m
Multiple Airlines
Deal found 1/20$865
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:09 pm
CHS
-
CUZ
2 stops20h 16m
American Airlines
Sun 5/109:00 pm
CUZ
-
CHS
2 stops21h 41m
American Airlines
Deal found 1/20$915
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/218:59 pm
CHS
-
CUZ
2 stops15h 21m
Multiple Airlines
Tue 3/311:40 pm
CUZ
-
CHS
2 stops20h 44m
Multiple Airlines
Deal found 1/21$975
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1011:04 am
CHS
-
CUZ
2 stops20h 26m
American Airlines
Sat 4/1812:50 pm
CUZ
-
CHS
2 stops20h 34m
American Airlines
Deal found 1/21$1,009
This KAYAK deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2912:53 pm
CHS
-
CUZ
2 stops20h 37m
LATAM Airlines
Mon 2/236:50 am
CUZ
-
CHS
2 stops17h 04m
LATAM Airlines
Deal found 1/21$1,111
This LATAM Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/17:00 pm
CHS
-
CUZ
2 stops15h 05m
LATAM Airlines
Thu 2/55:00 am
CUZ
-
CHS
2 stops18h 55m
LATAM Airlines
Deal found 1/19$1,170
This KAYAK deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:27 pm
CHS
-
CUZ
3 stops24h 43m
Multiple Airlines
Sat 4/188:15 pm
CUZ
-
CHS
2 stops19h 42m
Multiple Airlines
Deal found 1/21$3,172

Find flight deals from Charleston to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Round-trip from

$865
(Mytrip)
From Charleston to Cusco Velazco Astete
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Charleston to Cusco that are best for you.

Fly from

Charleston

Fly to

Cuzco

Route

Depart

Return

Price

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 5/1

7:00 am-9:05 pm

3 stops39h 05m

Cusco Velazco Astete

Sun 5/10

4:50 pm-2:40 pm

3 stops20h 50m

$865

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 5/1

8:09 pm-3:25 pm

2 stops20h 16m

Cusco Velazco Astete

Sun 5/10

9:00 pm-7:41 pm

2 stops21h 41m

$915

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 3/21

8:59 pm-11:20 am

2 stops15h 21m

Cusco Velazco Astete

Tue 3/31

1:40 pm-11:24 am

2 stops20h 44m

$975

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/10

11:04 am-6:30 am

2 stops20h 26m

Cusco Velazco Astete

Sat 4/18

12:50 pm-10:24 am

2 stops20h 34m

$1,009

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 2/1

7:00 pm-10:05 am

2 stops15h 05m

Cusco Velazco Astete

Thu 2/5

5:00 am-11:55 pm

2 stops18h 55m

$1,170

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/10

5:27 pm-5:10 pm

3 stops24h 43m

Cusco Velazco Astete

Sat 4/18

8:15 pm-4:57 pm

2 stops19h 42m

$3,172

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Best time to book a flight from Charleston to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Cusco?

    Airlines like American Airlines and LATAM Airlines fly from Charleston to Cusco in about 15h 05m. The time it takes to get you to your destination can typically vary by up to 5h 11m. Charleston and Cusco are separated by a distance of 3250 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Charleston to Cuzco that include hotel bookings?

    Yes. In addition to deals on Charleston to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Cuzco.

  • Can I find deals for business class flights from Charleston to Cuzco?

    Yes. Cheapflights offers flight deals from Charleston to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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