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$863+ Cheap flights from Charleston (CHS) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Cheap flight deals from Charleston to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 17, 2025.

Round-trip from

$863
(American Airlines)
From Charleston to Cusco Velazco Astete
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Find flight deals from Charleston to Cuzco

Cheapest flights from Charleston to Cuzco
Explore the most affordable flight options available from Charleston to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This LATAM Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:15 amCHS - CUZ
2 stops21h 50mLATAM Airlines
Tue 12/97:30 amCUZ - CHS
2 stops16h 20mLATAM Airlines
Deal found 11/15$1,094
This Orbitz deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:35 amCHS - CUZ
2 stops17h 05mLATAM Airlines
Sat 12/2710:50 pmCUZ - CHS
2 stops42h 23mLATAM Airlines
Deal found 11/16$1,276
This Mytrip deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:49 pmCHS - CUZ
3 stops33h 37mMultiple Airlines
Sat 12/279:42 pmCUZ - CHS
3 stops23h 41mMultiple Airlines
Deal found 11/16$1,303
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:31 pmCHS - CUZ
3 stops16h 45mAmerican Airlines
Sat 12/279:42 pmCUZ - CHS
2 stops21h 45mAmerican Airlines
Deal found 11/16$2,447

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Charleston to Cusco that are best for you.

Fly from

Charleston

Fly to

Cuzco

Route

Depart

Return

Price

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Mon 2/16

8:15 pm-3:51 pm

2 stops19h 36m

Cusco Velazco Astete

Sun 3/1

9:02 pm-10:16 am

2 stops13h 14m

$863

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Mon 2/2

7:20 pm-10:26 am

2 stops15h 06m

Cusco Velazco Astete

Wed 2/4

12:52 pm-8:47 am

2 stops19h 55m

$1,041

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 12/6

11:15 am-9:05 am

2 stops21h 50m

Cusco Velazco Astete

Tue 12/9

7:30 am-11:50 pm

2 stops16h 20m

$1,094

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 12/14

7:35 am-12:40 am

2 stops17h 05m

Cusco Velazco Astete

Sat 12/27

10:50 pm-5:13 pm

2 stops42h 23m

$1,276

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 12/14

9:49 pm-7:26 am

3 stops33h 37m

Cusco Velazco Astete

Sat 12/27

9:42 pm-9:23 pm

3 stops23h 41m

$1,303

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 12/14

6:31 pm-11:16 am

3 stops16h 45m

Cusco Velazco Astete

Sat 12/27

9:42 pm-7:27 pm

2 stops21h 45m

$2,447

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Best time to book a flight from Charleston to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Cusco?

    Airlines like American Airlines and LATAM Airlines fly from Charleston to Cusco in about 19h 36m. The time it takes to get you to your destination can typically vary by up to 2h 14m. Charleston and Cusco are separated by a distance of 3250 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Charleston to Cuzco that include hotel bookings?

    Yes. In addition to deals on Charleston to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Cuzco.

  • Can I find deals for business class flights from Charleston to Cuzco?

    Yes. Cheapflights offers flight deals from Charleston to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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