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Cuzco

$589+ Cheap flights from Charleston (CHS) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Mar 3 — Mar 101
Tue 3/3
Tue 3/10
1 adult, Economy
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Cheap flight deals from Charleston to Cuzco

Cheapest flights from Charleston to Cuzco
Explore the most affordable flight options available from Charleston to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 1, 2026.

This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:07 am
CHS
-
CUZ
2 stops24h 13m
Multiple Airlines
Wed 3/259:32 pm
CUZ
-
CHS
3 stops23h 41m
Multiple Airlines
Deal found 1/31$589
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:08 pm
CHS
-
CUZ
2 stops15h 57m
GOL
Sat 4/184:15 pm
CUZ
-
CHS
2 stops17h 09m
GOL
Deal found 1/30$960
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:08 pm
CHS
-
CUZ
2 stops35h 17m
GOL
Fri 4/1710:25 pm
CUZ
-
CHS
2 stops20h 12m
GOL
Deal found 1/30$994
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:08 pm
CHS
-
CUZ
2 stops36h 12m
GOL
Sat 4/187:45 pm
CUZ
-
CHS
2 stops13h 39m
GOL
Deal found 1/30$995
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:08 pm
CHS
-
CUZ
2 stops21h 23m
American Airlines
Wed 3/258:57 pm
CUZ
-
CHS
2 stops21h 25m
American Airlines
Deal found 1/31$1,001
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:09 pm
CHS
-
CUZ
2 stops15h 16m
LATAM Airlines
Fri 4/175:00 am
CUZ
-
CHS
2 stops18h 22m
LATAM Airlines
Deal found 1/30$1,057
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:40 pm
CHS
-
CUZ
2 stops35h 30m
Multiple Airlines
Sat 4/182:15 pm
CUZ
-
CHS
3 stops43h 08m
Multiple Airlines
Deal found 1/30$1,091
This LATAM Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/110:31 am
CHS
-
CUZ
2 stops19h 44m
LATAM Airlines
Tue 3/107:30 am
CUZ
-
CHS
2 stops15h 25m
LATAM Airlines
Deal found 1/30$1,120
This LATAM Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/17:00 pm
CHS
-
CUZ
2 stops15h 05m
LATAM Airlines
Thu 2/59:40 pm
CUZ
-
CHS
2 stops26h 15m
LATAM Airlines
Deal found 1/30$1,363
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:12 pm
CHS
-
CUZ
2 stops19h 08m
Multiple Airlines
Fri 4/1011:35 am
CUZ
-
CHS
3 stops45h 48m
Multiple Airlines
Deal found 2/1$1,393
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:40 am
CHS
-
CUZ
2 stops26h 05m
Multiple Airlines
Sat 4/182:15 pm
CUZ
-
CHS
3 stops43h 08m
Multiple Airlines
Deal found 1/30$1,423

Find flight deals from Charleston to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 1, 2026.

Round-trip from

$589
(Mytrip)
From Charleston to Cusco Velazco Astete
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
Use the filters below to find and compare flights from Charleston to Cusco that are best for you.

Fly from

Charleston

Fly to

Cuzco

Route

Depart

Return

Price

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Wed 3/18

8:07 am-7:20 am

2 stops24h 13m

Cusco Velazco Astete

Wed 3/25

9:32 pm-10:13 pm

3 stops23h 41m

$589

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Mon 4/6

8:08 pm-7:20 am

2 stops12h 12m

Cusco Velazco Astete

Fri 4/17

12:45 pm-10:24 am

2 stops20h 39m

$960

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Mon 4/6

8:08 pm-11:05 am

2 stops15h 57m

Cusco Velazco Astete

Sat 4/18

4:15 pm-10:24 am

2 stops17h 09m

$960

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Mon 4/6

8:08 pm-4:25 pm

2 stops21h 17m

Cusco Velazco Astete

Fri 4/10

5:15 pm-10:34 am

2 stops16h 19m

$960

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 4/5

8:08 pm-6:25 am

2 stops35h 17m

Cusco Velazco Astete

Fri 4/17

10:25 pm-7:37 pm

2 stops20h 12m

$994

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 4/5

8:08 pm-7:20 am

2 stops36h 12m

Cusco Velazco Astete

Sat 4/18

7:45 pm-10:24 am

2 stops13h 39m

$995

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Wed 3/18

8:08 pm-4:31 pm

2 stops21h 23m

Cusco Velazco Astete

Wed 3/25

8:57 pm-7:22 pm

2 stops21h 25m

$1,001

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 4/5

6:09 pm-8:25 am

2 stops15h 16m

Cusco Velazco Astete

Fri 4/17

5:00 am-12:22 am

2 stops18h 22m

$1,057

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 4/5

4:51 pm-8:25 am

2 stops16h 34m

Cusco Velazco Astete

Sat 4/18

5:00 am-11:50 pm

2 stops17h 50m

$1,057

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Mon 4/6

7:40 pm-6:10 am

2 stops35h 30m

Cusco Velazco Astete

Sat 4/18

2:15 pm-10:23 am

3 stops43h 08m

$1,091

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/31

Showing 1-10 of 11 results
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Best time to book a flight from Charleston to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Cusco?

    Airlines like GOL fly from Charleston to Cusco in about 12h 12m. The time it takes to get you to your destination can typically vary by up to . Charleston and Cusco are separated by a distance of 3250 mi.

  • Can I find deals for flights from Charleston to Cuzco that include hotel bookings?

    Yes. In addition to deals on Charleston to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Cuzco.

  • Can I find deals for business class flights from Charleston to Cuzco?

    Yes. Cheapflights offers flight deals from Charleston to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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