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$221+ Cheap flights from Biloxi, MS to Columbus

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — CMH
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Biloxi to Columbus

Cheapest flights from Biloxi to Columbus
Explore the most affordable flight options available from Biloxi to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:36 am
GPT
-
CMH
1 stop7h 13m
American Airlines
Tue 7/285:25 pm
CMH
-
GPT
1 stop7h 32m
American Airlines
Deal found 1/28$271
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/111:57 pm
GPT
-
CMH
2 stops8h 47m
United Airlines
Sun 2/156:10 am
CMH
-
GPT
1 stop8h 10m
United Airlines
Deal found 1/26$314
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/121:58 pm
GPT
-
CMH
1 stop7h 14m
United Airlines
Mon 2/166:10 am
CMH
-
GPT
1 stop8h 10m
United Airlines
Deal found 1/28$339
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:00 am
GPT
-
CMH
1 stop6h 02m
Delta
Sun 5/246:30 am
CMH
-
GPT
1 stop4h 07m
Delta
Deal found 1/28$407
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:00 am
GPT
-
CMH
1 stop7h 56m
United Airlines
Mon 2/166:10 am
CMH
-
GPT
1 stop8h 10m
United Airlines
Deal found 1/28$409
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/113:00 pm
GPT
-
CMH
1 stop6h 16m
Delta
Sun 2/155:02 pm
CMH
-
GPT
1 stop5h 52m
Delta
Deal found 1/26$435
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/141:58 pm
GPT
-
CMH
1 stop7h 14m
United Airlines
Wed 2/186:10 am
CMH
-
GPT
1 stop8h 10m
United Airlines
Deal found 1/26$517

Find flight deals from Biloxi to Columbus

Keep the following information in mind while searching for Biloxi to Columbus flight deals. Data was last updated January 29, 2026.

Round-trip from

$271
(American Airlines)

One-way from

$221
(Delta)

Popular in

September

Cheapest in

May

Average price

$348
From Biloxi to Columbus
Search Deals
One-way flight from Biloxi to Columbus
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Biloxi to Columbus that are best for you.

Fly from

Biloxi

Fly to

Columbus

Route

Depart

Return

Price

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Wed 7/22

5:36 am-1:49 pm

1 stop7h 13m

Columbus

Tue 7/28

2:39 pm-7:17 pm

1 stop5h 38m

$271

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Wed 2/11

1:57 pm-11:44 pm

2 stops8h 47m

Columbus

Sun 2/15

6:10 am-1:20 pm

1 stop8h 10m

$314

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Thu 2/12

1:58 pm-10:12 pm

1 stop7h 14m

Columbus

Mon 2/16

6:10 am-1:20 pm

1 stop8h 10m

$339

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Thu 5/21

6:00 am-1:02 pm

1 stop6h 02m

Columbus

Sun 5/24

6:30 am-9:37 am

1 stop4h 07m

$407

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Sat 3/28

6:00 am-12:00 pm

1 stop5h 00m

$221

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Wed 2/11

6:05 am-11:38 am

1 stop4h 33m

$291

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Wed 2/11

1:57 pm-11:44 pm

2 stops8h 47m

$296

GulfportColumbus

GPT - CMH

GPTCMH

Gulfport Biloxi Regional

Sat 3/28

6:00 am-6:15 pm

2 stops11h 15m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Biloxi to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Columbus

What is the cheapest month to book a flight from Biloxi to Columbus?

Currently, May is the cheapest month in which you can book a flight from Biloxi to Columbus (average of $54). Flying from Biloxi to Columbus in November is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated January 29, 2026.
See what other customers who have flown with Delta and American Airlines from Biloxi to Columbus have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Biloxi to Columbus?

    Airlines like American Airlines and United Airlines fly from Biloxi to Columbus in about 7h 13m. The time it takes to get you to your destination can typically vary by up to 1h 34m. There are 748 mi between Biloxi and Columbus. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Biloxi to Columbus that include hotel bookings?

    Yes. In addition to deals on Biloxi to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Columbus.

  • Can I find deals for business class flights from Biloxi to Columbus?

    Yes. Cheapflights offers flight deals from Biloxi to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Columbus?

    Currently, May is the cheapest month in which you can book a flight from Biloxi to Columbus (average of $54). Flying from Biloxi to Columbus in November is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Biloxi to Columbus

Discover the top 5 airlines that operate flights from Biloxi to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$61Average$167FlexibilityNo cancel feeOn-time65%
DeltaCheapest$189Average$374FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$413FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$278Average$369FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$292Average$386FlexibilityNo cancel feeOn-time63%

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