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Cayman Islands

$398+ Cheap flights from Mississippi to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — GCM
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Mississippi to Cayman Islands

Keep the following information in mind while searching for Mississippi to Cayman Islands flight deals. Data was last updated November 26, 2025.

Round-trip from

$398
(Delta)
From Mississippi to Cayman Islands
Search Deals

Find flight deals from Mississippi to Cayman Islands

Cheapest flights from Mississippi to Cayman Islands
Explore the most affordable flight options available from Mississippi to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Mytrip deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:17 pmMEM - GCM
2 stops19h 38mMultiple Airlines
Tue 12/234:45 pmGCM - MEM
3 stops27h 37mMultiple Airlines
Deal found 11/25$479
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amMEM - GCM
1 stop5h 36mDelta
Mon 12/293:42 pmGCM - MEM
1 stop6h 43mDelta
Deal found 11/25$500
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:32 pmMEM - GCM
1 stop16h 18mAmerican Airlines
Tue 12/2312:55 pmGCM - MEM
1 stop7h 44mAmerican Airlines
Deal found 11/24$532
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:00 amMEM - GCM
2 stops14h 18mAmerican Airlines
Mon 12/2912:55 pmGCM - MEM
1 stop7h 44mAmerican Airlines
Deal found 11/25$606
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:38 pmGPT - GCM
2 stops18h 12mAmerican Airlines
Tue 12/237:30 amGCM - GPT
2 stops17h 42mAmerican Airlines
Deal found 11/25$690
This Mytrip deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:17 pmMEM - GCM
3 stops23h 58mMultiple Airlines
Mon 12/292:50 pmGCM - MEM
2 stops29h 32mMultiple Airlines
Deal found 11/25$954

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Mississippi to the Cayman Islands that are best for you.

Fly from

Mississippi

Fly to

Cayman Islands

Route

Depart

Return

Price

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Sun 1/25

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Thu 1/29

2:05 pm-7:28 pm

1 stop6h 23m

$398

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Mon 1/12

1:21 pm-4:05 pm

3 stops25h 44m

George Town Owen Roberts Intl

Sat 1/17

2:34 pm-10:19 am

2 stops20h 45m

$450

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Mon 1/12

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Sat 1/17

3:25 pm-8:51 pm

1 stop6h 26m

$475

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Fri 1/9

5:50 am-2:40 pm

1 stop7h 50m

George Town Owen Roberts Intl

Fri 1/16

2:05 pm-9:51 pm

1 stop8h 46m

$475

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Thu 1/8

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Tue 1/13

2:05 pm-8:51 pm

1 stop7h 46m

$475

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Fri 12/19

8:17 pm-4:55 pm

2 stops19h 38m

George Town Owen Roberts Intl

Tue 12/23

4:45 pm-7:22 pm

3 stops27h 37m

$479

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Thu 1/8

8:37 am-8:20 pm

2 stops10h 43m

George Town Owen Roberts Intl

Tue 1/13

8:50 am-11:53 pm

1 stop16h 03m

$480

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Fri 1/9

8:37 am-8:20 pm

2 stops10h 43m

George Town Owen Roberts Intl

Fri 1/16

8:50 am-11:53 pm

1 stop16h 03m

$480

MemphisGeorge Town

MEM - GCM

MEMGCM

Memphis

Sun 1/25

5:54 pm-11:50 am

2 stops16h 56m

George Town Owen Roberts Intl

Thu 1/29

12:50 pm-8:32 pm

2 stops8h 42m

$485

AlexandriaGeorge Town

AEX - GCM

AEXGCM

Alexandria

Tue 1/27

6:06 am-8:20 pm

2 stops13h 14m

George Town Owen Roberts Intl

Thu 1/29

12:50 pm-10:59 pm

2 stops11h 09m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 13 results
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Best time to book a flight from Mississippi to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to the Cayman Islands
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Cayman Islands?

    Delta and American Airlines can get you from Mississippi to Cayman Islands in just under 5h 40m. Your travel time can differ by up to 7h 34m. The distance from Mississippi to Cayman Islands is about 1208 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mississippi to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Mississippi to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Cayman Islands.

  • Can I find deals for business class flights from Mississippi to Cayman Islands?

    Yes. Cheapflights offers flight deals from Mississippi to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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