$258+ Cheap flights from Harrisburg (MDT) to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GCM
Nov 11 — Nov 181
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to Cayman Islands with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Cayman Islands
Cheapest
Best
Last-minute
One-way
Cheapest flights from Harrisburg to Cayman IslandsExplore the most affordable flight options available from Harrisburg to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
Explore the most affordable flight options available from Harrisburg to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:05 pm -
2 stops19h 40m
Thu 11/198:23 am -
2 stops15h 50m
Deal found 10/8![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:45 am -
2 stops12h 08m
Sat 11/211:00 pm -
2 stops10h 03m
Deal found 10/10![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:59 am -
1 stop9h 08m
Sat 12/1212:16 pm -
1 stop10h 33m
Deal found 10/8![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:20 pm -
1 stop20h 25m
Mon 12/2112:31 pm -
1 stop10h 18m
Deal found 10/8![American Airlines logo]()
$450
Best flights from Harrisburg to Cayman IslandsDiscover carefully curated flight deals from Harrisburg to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
Discover carefully curated flight deals from Harrisburg to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/28:27 pm -
1 stop17h 45m
Wed 3/103:20 pm -
1 stop9h 04m
Deal found 10/8![American Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/206:00 am -
2 stops10h 15m
Sat 2/275:45 pm -
2 stops15h 50m
Deal found 10/11![United Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:12 am -
1 stop25h 11m
Thu 11/191:00 pm -
1 stop20h 23m
Deal found 10/8![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:45 am -
2 stops12h 08m
Sat 11/211:00 pm -
1 stop20h 23m
Deal found 10/10![American Airlines logo]()
$430
Last-minute flights from Harrisburg to Cayman IslandsDiscover last-minute flight deals from Harrisburg to Cayman Islands. Data last updated October 12, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Cayman Islands. Data last updated October 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am -
1 stop7h 30m
Wed 11/412:18 pm -
2 stops10h 40m
Deal found 10/11![American Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:30 am -
1 stop7h 15m
Wed 11/45:45 pm -
2 stops25h 12m
Deal found 10/7![United Airlines logo]()
$525
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:05 pm -
2 stops19h 40m
Thu 11/198:23 am -
2 stops15h 50m
Deal found 10/8![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:45 am -
2 stops12h 08m
Sat 11/211:00 pm -
2 stops10h 03m
Deal found 10/10![American Airlines logo]()
$422
One-way flights from Harrisburg to Cayman IslandsSearch for one-way flight options from Harrisburg to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated October 12, 2026.
Search for one-way flight options from Harrisburg to Cayman Islands. Find affordable one-way fares based on user searches. Data last updated October 12, 2026.
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:54 pm -
2 stops22h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:53 am -
3 stops50h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:00 am -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![American Airlines logo]()
$685
Find flight deals from Harrisburg to Cayman Islands
Keep the following information in mind while searching for Harrisburg to Cayman Islands flight deals. Data was last updated October 12, 2026.
Round-trip from | $391 (American Airlines) |
|---|---|
One-way from | $258 (United Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $906 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
Use the filters below to find and compare flights from Harrisburg to the Cayman Islands that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgGeorge Town
MDT Harrisburg - GCM George Town Owen Roberts Intl
MDTGCM
Harrisburg
Sat 10/24
5:54 pm-3:30 pm
2 stops22h 36m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$258
HarrisburgGeorge Town
MDT Harrisburg - GCM George Town Owen Roberts Intl
MDTGCM
Harrisburg
Tue 3/2
8:27 pm-2:12 pm
1 stop17h 45m
George Town Owen Roberts Intl
Wed 3/10
3:20 pm-12:24 am
1 stop9h 04m
$391
HarrisburgGeorge Town
MDT Harrisburg - GCM George Town Owen Roberts Intl
MDTGCM
Harrisburg
Thu 11/12
10:12 am-11:23 am
1 stop25h 11m
George Town Owen Roberts Intl
Thu 11/19
1:00 pm-9:23 am
1 stop20h 23m
$405
HarrisburgGeorge Town
MDT Harrisburg - GCM George Town Owen Roberts Intl
MDTGCM
Harrisburg
Sat 11/14
7:45 am-7:53 pm
2 stops12h 08m
George Town Owen Roberts Intl
Sat 11/21
1:00 pm-9:23 am
1 stop20h 23m
$430
HarrisburgGeorge Town
MDT Harrisburg - GCM George Town Owen Roberts Intl
MDTGCM
Harrisburg
Sat 2/20
6:00 am-4:15 pm
2 stops10h 15m
George Town Owen Roberts Intl
Sat 2/27
5:45 pm-9:35 am
2 stops15h 50m
$442
Quickest round-trip
HarrisburgGeorge Town
MDT Harrisburg - GCM George Town Owen Roberts Intl
MDTGCM
Harrisburg
Sat 10/24
5:00 am-11:30 am
1 stop7h 30m
George Town Owen Roberts Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$685
Sorted by cheapest first
Best time to book a flight from Harrisburg to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Harrisburg with our price prediction graph.
MDT-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to the Cayman Islands
MDT-KY0
MDT-GCM
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Cayman Islands
Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated October 12, 2026.
Get a feel of what it's like to fly with American Airlines from Harrisburg to the Cayman Islands by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Crew
7.9
Entertainment
6.8
Overall
7.0
Comfort
7.2
Boarding
7.4
Reviews
1 / 20
8.0
ExcellentAnonymous,May 2025
PHL - LHR
Food
6.4
Crew
7.9
Entertainment
6.8
Overall
7.0
Comfort
7.2
Boarding
7.4
Reviews
1 / 20
8.0
ExcellentAnonymous,May 2025
PHL - LHR
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Harrisburg to Cayman Islands
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Complete your trip
Complete your trip to Cayman Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Harrisburg and Cayman Islands flights
Browse other Harrisburg and Cayman Islands flight options. Last updated on October 12, 2026.
Popular flight searches
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Fly to Cayman Islands regions
Consider these flights traveling to Cayman Islands regions.
Top airline flying from Harrisburg to Cayman Islands
Discover the top airline that operate flights from Harrisburg to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$363 | Average$605 | FlexibilityNo cancel fee | On-time71% |