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Cayman Islands

$92+ Cheap flights from Durham, NC to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GCM
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Durham to Cayman Islands

Cheapest flights from Durham to Cayman Islands
Explore the most affordable flight options available from Durham to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:17 pmRDU - GCM
1 stop15h 40mAmerican Airlines
Fri 12/263:45 pmGCM - RDU
1 stop8h 48mAmerican Airlines
Deal found 12/20$288
This Delta deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:05 amRDU - GCM
1 stop6h 22mDelta
Sun 12/283:42 pmGCM - RDU
1 stop7h 07mDelta
Deal found 12/18$300
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amRDU - GCM
1 stop10h 35mUnited Airlines
Sun 12/285:45 pmGCM - RDU
1 stop17h 36mUnited Airlines
Deal found 12/20$319
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:38 amRDU - GCM
1 stop8h 47mAmerican Airlines
Sat 12/2712:47 pmGCM - RDU
1 stop9h 01mAmerican Airlines
Deal found 12/20$338
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:00 amRDU - GCM
1 stop4h 57mAmerican Airlines
Mon 12/2212:50 pmGCM - RDU
1 stop11h 43mAmerican Airlines
Deal found 12/19$363
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:31 amRDU - GCM
1 stop7h 14mUnited Airlines
Sun 12/285:45 pmGCM - RDU
1 stop17h 36mUnited Airlines
Deal found 12/19$373
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:17 pmRDU - GCM
1 stop15h 40mAmerican Airlines
Thu 1/13:45 pmGCM - RDU
1 stop8h 48mAmerican Airlines
Deal found 12/20$388
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:25 amRDU - GCM
2 stops8h 53mAmerican Airlines
Sun 12/2812:55 pmGCM - RDU
1 stop8h 53mAmerican Airlines
Deal found 12/20$398
This Kiwi.com deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:50 pmRDU - GCM
1 stop19h 55mMultiple Airlines
Sun 1/42:40 pmGCM - RDU
2 stops21h 40mMultiple Airlines
Deal found 12/18$420
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:16 pmRDU - GCM
2 stops19h 45mAmerican Airlines
Sun 12/283:11 pmGCM - RDU
1 stop8h 45mAmerican Airlines
Deal found 12/18$431

Find flight deals from Durham to Cayman Islands

Keep the following information in mind while searching for Durham to Cayman Islands flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$286
(American Airlines)

One-way from

$92
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$553
Provider with most accurate pricing for Raleigh-Durham-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-George Town Owen Roberts Intl flights.
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From Durham to Cayman Islands
Search Deals
One-way flight from Durham to Cayman Islands
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Durham to the Cayman Islands that are best for you.

Fly from

Durham

Fly to

Cayman Islands

Route

Depart

Return

Price

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Fri 2/6

6:00 am-11:26 am

1 stop5h 26m

George Town Owen Roberts Intl

Tue 2/10

3:45 pm-9:39 pm

1 stop5h 54m

$286

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Sun 1/25

6:15 am-1:45 pm

1 stop7h 30m

George Town Owen Roberts Intl

Sat 1/31

5:30 pm-11:44 pm

1 stop6h 14m

$288

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Fri 1/23

7:35 pm-11:26 am

1 stop15h 51m

George Town Owen Roberts Intl

Wed 1/28

3:45 pm-9:39 pm

1 stop5h 54m

$288

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Sat 1/3

8:48 pm-11:57 am

1 stop15h 09m

George Town Owen Roberts Intl

Sat 1/10

12:35 pm-8:22 pm

1 stop7h 47m

$288

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Thu 1/22

7:35 pm-11:26 am

1 stop15h 51m

George Town Owen Roberts Intl

Tue 1/27

1:05 pm-9:39 pm

1 stop8h 34m

$288

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Wed 1/21

8:04 am-8:20 pm

2 stops12h 16m

$92

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Tue 12/30

10:45 am-4:35 pm

1 stop5h 50m

$92

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Wed 12/31

5:00 am-12:01 pm

1 stop7h 01m

$92

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Sun 3/29

4:20 pm-1:25 pm

2 stops22h 05m

$128

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Sat 3/28

1:13 pm-2:25 pm

2 stops26h 12m

$128

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 12 results
1
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Best time to book a flight from Durham to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to the Cayman Islands

What is the cheapest month to book a flight from Durham to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Durham to Cayman Islands (average of $282). Flying from Durham to Cayman Islands in November is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to KY?

Find hourly flight availability from Durham to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2025.

It’s typically best to fly out from Durham to Cayman Islands in the evening. Doing so could potentially save you 22% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated December 21, 2025.
Read through reviews of airlines operating flights from Durham to the Cayman Islands, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,021 reviews

Boarding

8.1

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,021 reviews
Delta
7.9
Good
8,021 reviews

Boarding

8.1

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,099 reviews
Delta
7.9
Good
8,021 reviews

Boarding

8.1

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,021 reviews

Boarding

8.1

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to Cayman Islands?

    Departing from Durham to Cayman Islands will take you 5h 26m. Airlines will cover a distance of 1156 mi.

  • Can I find deals for flights from Durham to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Durham to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Cayman Islands.

  • Can I find deals for business class flights from Durham to Cayman Islands?

    Yes. Cheapflights offers flight deals from Durham to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Durham to Cayman Islands (average of $282). Flying from Durham to Cayman Islands in November is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Durham to Cayman Islands

Discover the top 3 airlines that operate flights from Durham to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$256Average$478FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$362Average$481FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$391Average$597FlexibilityNo cancel feeOn-time71%

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