HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$108+ Cheap flights from Durham, NC to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — GCM
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Durham to Cayman Islands

Cheapest flights from Durham to Cayman Islands
Explore the most affordable flight options available from Durham to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 amRDU - GCM
1 stop7h 06mDelta
Mon 12/293:42 pmGCM - RDU
1 stop7h 07mDelta
Deal found 12/3$320
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:38 amRDU - GCM
1 stop8h 47mAmerican Airlines
Thu 12/251:03 pmGCM - RDU
2 stops21h 31mAmerican Airlines
Deal found 12/2$338
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:15 amRDU - GCM
1 stop7h 20mDelta
Wed 12/101:50 pmGCM - RDU
1 stop8h 25mDelta
Deal found 12/2$340
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:21 pmRDU - GCM
2 stops16h 49mAmerican Airlines
Wed 12/101:25 pmGCM - RDU
2 stops18h 41mAmerican Airlines
Deal found 12/2$345
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:50 pmRDU - GCM
1 stop19h 55mMultiple Airlines
Sun 12/282:40 pmGCM - RDU
2 stops21h 40mMultiple Airlines
Deal found 12/2$380
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:18 pmRDU - GCM
2 stops20h 27mMultiple Airlines
Thu 12/257:00 amGCM - RDU
1 stop9h 58mMultiple Airlines
Deal found 12/2$388
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:21 pmRDU - GCM
2 stops17h 03mAmerican Airlines
Sat 12/133:19 pmGCM - RDU
1 stop6h 30mAmerican Airlines
Deal found 12/1$405
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:14 pmRDU - GCM
1 stop17h 21mMultiple Airlines
Thu 12/252:40 pmGCM - RDU
2 stops9h 33mMultiple Airlines
Deal found 12/2$409
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:05 pmRDU - GCM
2 stops22h 30mMultiple Airlines
Sun 12/282:40 pmGCM - RDU
1 stop26h 15mMultiple Airlines
Deal found 12/3$411
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:30 amRDU - GCM
1 stop6h 57mDelta
Tue 12/233:42 pmGCM - RDU
1 stop7h 07mDelta
Deal found 12/2$417
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:14 pmRDU - GCM
2 stops17h 31mMultiple Airlines
Tue 12/237:00 amGCM - RDU
1 stop10h 19mMultiple Airlines
Deal found 12/2$420

Find flight deals from Durham to Cayman Islands

Keep the following information in mind while searching for Durham to Cayman Islands flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$295
(JetBlue)

One-way from

$108
(American Airlines)

Popular in

October

Cheapest in

September

Average price

$582
Provider with most accurate pricing for Raleigh-Durham-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-George Town Owen Roberts Intl flights.
Search Deals
From Durham to Cayman Islands
Search Deals
One-way flight from Durham to Cayman Islands
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Durham to the Cayman Islands that are best for you.

Fly from

Durham

Fly to

Cayman Islands

Route

Depart

Return

Price

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Sat 1/24

7:00 am-1:55 pm

1 stop6h 55m

George Town Owen Roberts Intl

Sat 1/31

2:55 pm-10:59 pm

1 stop8h 04m

$295

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Tue 1/20

7:00 am-1:55 pm

1 stop6h 55m

George Town Owen Roberts Intl

Sat 1/31

2:55 pm-10:59 pm

1 stop8h 04m

$302

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Tue 1/13

5:15 am-12:40 pm

1 stop7h 25m

George Town Owen Roberts Intl

Sat 1/17

2:05 pm-12:15 am

1 stop10h 10m

$312

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Fri 1/23

6:59 pm-12:50 pm

1 stop17h 51m

George Town Owen Roberts Intl

Tue 1/27

2:05 pm-12:15 am

1 stop10h 10m

$312

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Sat 1/24

5:15 am-10:57 am

1 stop5h 42m

George Town Owen Roberts Intl

Tue 1/27

2:05 pm-12:15 am

1 stop10h 10m

$312

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Fri 1/23

7:50 pm-10:57 am

1 stop15h 07m

George Town Owen Roberts Intl

Mon 1/26

2:05 pm-8:40 pm

1 stop6h 35m

$312

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Mon 2/2

5:15 am-12:40 pm

1 stop7h 25m

George Town Owen Roberts Intl

Sat 2/7

2:05 pm-9:35 pm

1 stop7h 30m

$312

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Mon 1/26

5:15 am-12:40 pm

1 stop7h 25m

George Town Owen Roberts Intl

Sat 1/31

3:25 pm-9:35 pm

1 stop6h 10m

$313

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Thu 1/22

5:15 am-12:40 pm

1 stop7h 25m

George Town Owen Roberts Intl

Mon 1/26

2:05 pm-8:40 pm

1 stop6h 35m

$320

RaleighGeorge Town

RDU - GCM

RDUGCM

Raleigh-Durham

Wed 12/24

8:05 am-2:27 pm

1 stop6h 22m

George Town Owen Roberts Intl

Mon 12/29

1:52 pm-11:57 pm

1 stop10h 05m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 15 results
1
2

Best time to book a flight from Durham to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to the Cayman Islands

What is the cheapest month to book a flight from Durham to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Durham to Cayman Islands (average of $320). Flying from Durham to Cayman Islands in August is currently the most expensive (average of $427). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to KY?

Find hourly flight availability from Durham to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s typically best to fly out from Durham to Cayman Islands in the evening. Doing so could potentially save you 22% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Durham to the Cayman Islands, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to Cayman Islands?

    Departing from Durham to Cayman Islands will take you 6h 55m. Airlines will cover a distance of 1156 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Durham to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Durham to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Cayman Islands.

  • Can I find deals for business class flights from Durham to Cayman Islands?

    Yes. Cheapflights offers flight deals from Durham to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Durham to Cayman Islands (average of $320). Flying from Durham to Cayman Islands in August is currently the most expensive (average of $427). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
Raleigh to Luis Munoz Marin Intl flights
Charlotte to Luis Munoz Marin Intl flights
Charlotte to Punta Cana flights
Norfolk to Luis Munoz Marin Intl flights
Raleigh to Punta Cana flights
Charlotte to Montego Bay flights
Charlotte to Saint Thomas Island flights
Charlotte to Willemstad flights
Charlotte to Providenciales flights
Charlotte to Oranjestad flights
Charlotte to Nassau flights
Raleigh to Saint Thomas Island flights
Raleigh to Nassau flights
Raleigh to Montego Bay flights
Charlotte to Castries flights
Raleigh to Oranjestad flights
Greensboro to Luis Munoz Marin Intl flights
Charlotte to Bridgetown flights
Charlotte to Simpson Bay flights
Charlotte to Santo Domingo flights
Norfolk to Punta Cana flights
Asheville to Luis Munoz Marin Intl flights
Raleigh to Providenciales flights
Charlotte to George Town flights
Charlotte to Puerto Plata flights
Charlotte to Christiansted flights
Raleigh to Santo Domingo flights
Raleigh to Castries flights
Raleigh to Simpson Bay flights
Norfolk to Montego Bay flights
Greensboro to Punta Cana flights
Charlotte to St. John's flights
Norfolk to Saint Thomas Island flights
Raleigh to St. John's flights
Raleigh to Kingston flights
Myrtle Beach to Punta Cana flights
Wilmington to Luis Munoz Marin Intl flights
Raleigh to Willemstad flights
Charlotte to Gregory Town flights
Charlotte to Marsh Harbour flights
Myrtle Beach to Luis Munoz Marin Intl flights
Knoxville to Luis Munoz Marin Intl flights
Greensboro to Saint Thomas Island flights
Wilmington to Punta Cana flights
Raleigh to George Town flights
Raleigh to Puerto Plata flights
Raleigh to Christiansted flights
Norfolk to Bridgetown flights
Knoxville to Oranjestad flights
Charlotte to Road Town flights

Top 3 airlines flying from Durham to Cayman Islands

Discover the top 3 airlines that operate flights from Durham to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$360Average$478FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$362Average$481FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$371Average$594FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.